Science Magazine
Human DNA-PK activates a STING-independent DNA sensing pathway  Science Magazine · 7 hours
Detection of intracellular DNA by the cGAS-STING pathway activates a type I interferon-mediated innate immune response that protects from virus infection. Whether there are additional DNA sensing pathways, and how such pathways... more
Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation  Science Magazine · 7 hours
T follicular helper cells (TFH) participate in germinal center (GC) development and are necessary for B cell production of high-affinity, isotype-switched antibodies. In a... more
The global-scale distributions of soil protists and their contributions to belowground systems  Science Magazine · 7 hours
Protists are ubiquitous in soil, where they are key contributors to nutrient cycling and energy transfer. However, protists have received far less attention than... more
Direct observation of glucose fingerprint using in vivo Raman spectroscopy  Science Magazine · 7 hours
Noninvasive blood glucose monitoring has been a long-standing dream in diabetes management. The use of Raman spectroscopy, with its molecular specificity, has been investigated in this regard over... more
Structural and spectral dynamics of single-crystalline Ruddlesden-Popper phase halide perovskite blue light-emitting diodes  Science Magazine · 7 hours
Achieving perovskite-based high–color purity blue-emitting light-emitting diodes (LEDs) is still challenging. Here, we report successful synthesis of a series of blue-emissive two-dimensional... more
Weak-field induced nonmagnetic state in a Co-based honeycomb  Science Magazine · 7 hours
Layered honeycomb magnets are of interest as potential realizations of the Kitaev quantum spin liquid (KQSL), a quantum state with long-range spin entanglement and an exactly solvable Hamiltonian. Conventional magnetically ordered states... more
Community detection in networks without observing edges  Science Magazine · 7 hours
We develop a Bayesian hierarchical model to identify communities of time series. Fitting the model provides an end-to-end community detection algorithm that does not extract information as a sequence of point estimates but propagates... more
On the design of precision nanomedicines  Science Magazine · 7 hours
Tight control on the selectivity of nanoparticles’ interaction with biological systems is paramount for the development of targeted therapies. However, the large number of tunable parameters makes it difficult to identify optimal design "sweet spots" without... more
Large-scale synthesis of crystalline g-C3N4 nanosheets and high-temperature H2 sieving from assembled films  Science Magazine · 7 hours
Poly(triazine imide) (PTI), a crystalline g-C3N4, hosting two-dimensional nanoporous structure with an electron density gap of 0.34 nm, is highly promising for... more
Cargo capture and transport by colloidal swarms  Science Magazine · 7 hours
Controlling active colloidal particle swarms could enable useful microscopic functions in emerging applications at the interface of nanotechnology and robotics. Here, we present a computational study of controlling self-propelled colloidal particle propulsion speeds to... more
Small-scale universality in the spectral structure of transitional pipe flows  Science Magazine · 7 hours
Turbulent flows are not only everywhere, but every turbulent flow is the same at small scales. The extraordinary simplification engendered by this "small-scale universality" is a hallmark of... more
Can polarity-inverted membranes self-assemble on Titan?  Science Magazine · 7 hours
The environmental and chemical limits of life are two of the most central questions in astrobiology. Our understanding of life’s boundaries has implications on the efficacy of biosignature identification in exoplanet atmospheres and in the solar... more
Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli  Science Magazine · 7 hours
Plasmids are key vehicles of horizontal gene transfer (HGT), mobilizing antibiotic resistance, virulence, and other traits among bacterial populations. The environmental and genetic forces that drive... more
Bioinspired structural color patch with anisotropic surface adhesion  Science Magazine · 7 hours
Patch plays an important role in clinical medicine for its broad applications in tissue repair and regeneration. Here, inspired by the diverse adhesion, anti-adhesion, and responsive structural color phenomena in biological interfaces,... more
A highly scalable dielectric metamaterial with superior capacitor performance over a broad temperature  Science Magazine · 7 hours
Although many polymers exhibit excellent dielectric performance including high energy density with high efficiency at room temperature, their electric and dielectric performance... more
Multidimensional entanglement transport through single-mode fiber  Science Magazine · 7 hours
The global quantum network requires the distribution of entangled states over long distances, with substantial advances already demonstrated using polarization. While Hilbert spaces with higher dimensionality, e.g., spatial modes of light, allow higher information capacity per... more
WHO says no need—yet—to declare spread of novel virus is an international emergency  Science Magazine · 1 day
Critics of decision see global threat from a coronavirus that emerged in China last month and has jumped to several countries more
To replace controversial plastic additive BPA, a chemical company teams up with unlikely allies  Science Magazine · 1 day
To test its new compound, Sherwin-Williams sought help from scientists and environmental groups critical of bisphenol A more
Lineage tracing on transcriptional landscapes links state to fate during differentiation  Science Magazine · 1 day
A challenge in biology is to associate molecular differences among progenitor cells with their capacity to generate mature cell types. Here, we use expressed DNA barcodes... more
Quantum anomalous Hall effect in intrinsic magnetic topological insulator MnBi2Te4  Science Magazine · 1 day
In a magnetic topological insulator, nontrivial band topology conspires with magnetic order to produce exotic states of matter such as quantum anomalous Hall (QAH) insulators and axion insulators.... more
Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in C. elegans  Science Magazine · 1 day
The ability of the nervous system to sense cellular stress and coordinate protein homeostasis is essential for organismal... more
Rational construction of a scalable heterostructured nanorod megalibrary  Science Magazine · 1 day
Integrating multiple materials in arbitrary arrangements within nanoparticles is a prerequisite for advancing many applications. Strategies to synthesize heterostructured nanoparticles are emerging, but they are limited in complexity, scope, and scalability. We... more
Chromatin accessibility dynamics in a model of human forebrain development  Science Magazine · 1 day
Forebrain development is characterized by highly synchronized cellular processes, which, if perturbed, can cause disease. To chart the regulatory activity underlying these events, we generated a map of... more
Phase separation provides a mechanism to reduce noise in cells  Science Magazine · 1 day
Expression of proteins inside cells is noisy, causing variability in protein concentration among identical cells. A central problem in cellular control is how cells cope with this inherent... more
A tensile ring drives tissue flows to shape the gastrulating amniote embryo  Science Magazine · 1 day
Tissue morphogenesis is driven by local cellular deformations that are powered by contractile actomyosin networks. How localized forces are transmitted across tissues to shape... more
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