Pharmaceuticals
New molecular mechanism that regulates the sentinel cells of the immune system  NEWS MEDICAL · 1 hour
A study suggests that it may be possible to regulate macrophages with drugs that modulate the nuclear receptor RXR. more
The Latest: France warding off shortages of essential drugs  ABC NEWS · 3 hours
France’s prime minister says he and his government colleagues are “fighting hour by hour” to ward off shortages of essential drugs used to keep COVID-19 patients alive in intensive care more
Robots can play a major role in COVID-19 battle  NEWS MEDICAL · 7 hours
Robots can significantly help in the fight against the coronavirus disease (COVID-19) that is spreading across the globe. As the number of cases tops one million, and the death toll... more
Who should be taking antimalarial drugs as treatment against COVID-19?  NEWS MEDICAL · 8 hours
Researchers provide a guideline regarding who should be actually taking antimalarial drugs as prophylaxis to prevent getting COVID-19. They say health professionals who are being exposed to COVID-19... more
Drugs considered for COVID-19 can increase risk for dangerous arrhythmias  NEWS MEDICAL · 9 hours
As some consider treating coronavirus patients with a combination of the malaria drug hydroxychloroquine and the antibiotic azithromycin, cardiologists are advising caution because both medications can increase the... more
Promising vaccine patch candidate for COVID-19  NEWS MEDICAL · 10 hours
In a breath of fresh air, scientists from the University of Pittsburgh School of Medicine reported that they had developed a potential new vaccine against the SARS-CoV-2 virus, which is causing the current COVID-19 pandemic. The... more
Magnetic stimulation of rectal nerves could help treat fecal incontinence  NEWS MEDICAL · 11 hours
An ongoing study by the Medical College of Georgia on the role of magnetic stimulation of the rectal nerves to achieve better bowel control in patients with fecal... more
Trial drug could potentially inhibit COVID-19, study shows  NEWS MEDICAL · 11 hours
A drug already tested against lung disease could potentially inhibit COVID-19 by reducing the coronavirus load that enters the lungs and other organs. more
Studies shed light on the link between obesity and use of prescription opioids  NEWS MEDICAL · 12 hours
Two new studies from the Boston University School of Public Health shed light on the relationship between obesity and the use of... more
Potential of using psychedelic drugs in psychiatry  SCIENCE DAILY · 14 hours
Before they were banned about a half century ago, psychedelic drugs like LSD and psilocybin showed promise for treating conditions including alcoholism and some psychiatric disorders. Researchers say it's time for regulators, scientists, and... more
COVID-19 vaccine candidate shows promise, research shows  SCIENCE DAILY · 15 hours
Scientists have announced a potential vaccine against SARS-CoV-2, the new coronavirus causing the COVID-19 pandemic. When tested in mice, the vaccine -- delivered through a fingertip-sized patch -- produces antibodies specific to SARS-CoV-2 at... more
COVID-19 vaccine candidate shows promise in first peer-reviewed research  SCIENCE DAILY · 15 hours
A potential COVID-19 vaccine, delivered by microscopic needles, produces antibodies specific to the virus when tested in mice. This is the first peer-reviewed paper describing a COVID-19 vaccine candidate. The... more
Trial drug can significantly block early stages of COVID-19 in engineered human tissues  SCIENCE DAILY · 15 hours
An international team has found a trial drug that effectively blocks the cellular door SARS-CoV-2 uses to infect its hosts. more
COVID-19 Candidate Vaccine Shows Promise in Mouse Study  SCI-NEWS.COM · 15 hours
A team of researchers at the University of Pittsburgh and Erasmus Medical Center Rotterdam has developed a potential vaccine against... more
Newly discovered biostability in DNA structures may lead to enhanced design of therapeutics  nanowerk · 17 hours
Researchers discovered an already existing biostable DNA motif applicable to the design of new drug carriers and diagnostics. more
These drugs don’t target the coronavirus—they target us  Science Magazine · 19 hours
Scientists are testing dozens of compounds that might inhibit infection by blocking a human protein more
Study shows efficacy of parent-based treatment for childhood anxiety  NEWS MEDICAL · 20 hours
A study in the Journal of the American Academy of Child and Adolescent Psychiatry, published by Elsevier, reports that an entirely parent-based treatment, SPACE (Supportive Parenting for Anxious Childhood Emotions),... more
Biogazelle initiates large-scale testing of patient samples for SARS-CoV-2  NEWS MEDICAL · 20 hours
Biogazelle NV, a CRO specialized in RNA analytics, has announced the initiation of large-scale testing of patient samples for SARS-CoV-2. Biogazelle is providing one of the multiple testing sites in... more
A map of reactions helps control molecular properties  PHYS.ORG · 21 hours
Chemical reactions are used to produce all kinds of important molecules such as drugs, agrochemicals and materials. more
Majority of patients with mantle cell lymphoma may benefit from CAR T-cell therapy KTE-X19  NEWS MEDICAL · 1 day
A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with... more
Duke to lead PCORI-funded study of COVID-19 prevention in healthcare workers  NEWS MEDICAL · 1 day
The Patient-Centered Outcomes Research Institute has funded up to $50 million to evaluate hydroxychloroquine (HCQ) as a preventive drug for the novel coronavirus. more
Judge dismisses pharmacies' lawsuit against physicians  ABC NEWS · 2 days
A federal judge in Cleveland has dismissed an effort by pharmacy chains to shift their liability for the opioid crisis to unnamed Ohio physicians and practitioners who wrote the painkiller prescriptions pharmacists filled more
On Mars or Earth, biohybrid can turn carbon dioxide into new products  SCIENCE DAILY · 2 days
Chemists have created a hybrid system of bacteria and nanowires that captures energy from sunlight and transfers it to the bacteria to turn carbon... more
Remdesivir Has Therapeutic Potential against SARS-CoV-2 Coronavirus, Scientists Say  SCI-NEWS.COM · 2 days
Two new papers published in the journal Antimicrobial Agents and Chemotherapy provide a summary of therapeutic compounds that... more
Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide  Science Magazine · 2 days
Low oral bioavailability of peptide drugs has limited their application to parenteral administration, which suffers from poor patient compliance. Here, we show that molecular targeting of... more
Epitope-directed antibody selection by site-specific photocrosslinking  Science Magazine · 2 days
Currently, there are no methods available offering solutions to select and identify antibodies binding to a specific conformational epitope of an antigen. Here, we developed a method to allow epitope-directed antibody selection from a phage display... more
A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application  Science Magazine · 2 days
Although growth factors have great therapeutic potential because of their regenerative functions, they often have intrinsic drawbacks, such as low... more
Pretargeted delivery of PI3K/mTOR small-molecule inhibitor-loaded nanoparticles for treatment of non-Hodgkins lymphoma  Science Magazine · 2 days
Overactivation of the PI3K/mTOR signaling has been identified in non-Hodgkin’s lymphoma. BEZ235 is an effective dual PI3K/mTOR inhibitor, but it was withdrawn from early-phase... more
Designer, injectable gels to prevent transplanted Schwann cell loss during spinal cord injury therapy  Science Magazine · 2 days
Transplantation of patient-derived Schwann cells is a promising regenerative medicine therapy for spinal cord injuries; however, therapeutic efficacy is compromised... more
Blocking the iron transport could stop tuberculosis  SCIENCE DAILY · 2 days
The bacteria that cause tuberculosis need iron to survive. Researchers have now solved the first detailed structure of the transport protein responsible for the iron supply. When the iron transport into the bacteria is... more
[Research Articles] Spontaneous reversal of stenosis in tissue-engineered vascular grafts  Science Magazine · 2 days
We developed a tissue-engineered vascular graft (TEVG) for use in children and present results of a U.S. Food and Drug Administration (FDA)–approved clinical trial evaluating this graft in... more
New 3-D cultured cells mimic the progress of NASH  PHYS.ORG · 2 days
A research team led by scientists from Tokyo University of Agriculture and Technology (TUAT), Japan, has successfully established 3-D cultured tissue that mimics liver fibrosis, a key characteristic of non-alcoholic... more
Virus outbreak creates new challenges for addiction recovery  ABC NEWS · 2 days
The coronavirus pandemic is testing the resilience of millions who struggle with drug and alcohol addiction more
FDA wants heartburn meds off the market due to contamination  ABC NEWS · 2 days
The U.S. Food and Drug Administration is telling drugmakers to immediately pull a type of heartburn drug off the market due to contamination with a chemical that may... more
The discovery of new compounds for acting on the circadian clock  PHYS.ORG · 2 days
The circadian clock controls a variety of biological phenomena that occur during the course of the day, such as sleeping and waking. Perturbation of the circadian... more
Blocking iron transport could stop tuberculosis  PHYS.ORG · 2 days
One of the most devastating pathogens that lives inside human cells is Mycobacterium tuberculosis, the bacillus that causes tuberculosis. According to the World Health Organization, 1.5 million people died in 2019 from this disease that generally... more
Chinese scientists seeking potential COVID-19 treatment find 'effective' antibodies  REUTERS · 2 days
A team of Chinese scientists has isolated several antibodies that it says are "extremely effective" at blocking the... more
Stem cells used to combat COVID-19 pneumonia  NEWS MEDICAL · 2 days
The novel coronavirus first emerged in December 2019, and since then, it rippled across 180 countries, affecting hundreds of thousands of people. Amid the coronavirus disease (COVID-19) pandemic, many people are looking for answers.... more
New collaboration may lead to future clinical trials to test treatment for leukemia  NEWS MEDICAL · 2 days
In a new pre-clinical study published this week in the journal Leukemia, the research team of Children's Hospital Los Angeles investigator Hisham... more
Study: Medical product companies with female directors issue recalls more quickly  NEWS MEDICAL · 2 days
Medical product companies, such as those that make pharmaceuticals and medical devices, make recall decisions quite differently as women are added to their board of directors,... more
Pancreatitis drug Nafamostat shows promise for coronavirus  NEWS MEDICAL · 2 days
With the increasing number of infections across the globe, scientists have resorted to studying existing drugs in the hope of discovering a cure for the coronavirus disease (COVID-19). A team of researchers has found... more
Purdue scientists working to speed up diagnostic, therapeutic solutions for COVID-19  NEWS MEDICAL · 2 days
As the coronavirus pandemic spreads across the U.S. and the world, Purdue University scientists are working to move solutions to diagnose and treat the virus to... more
Researchers say that NSAIDs, JAK inhibitors and TNF blockers are safe to use in COVID-19  NEWS MEDICAL · 2 days
Amid the coronavirus disease (COVID-19) pandemic, many theories have emerged about the disease and the treatments that can... more
Researchers identify new therapeutic strategies against cancer  NEWS MEDICAL · 2 days
New findings open up to new therapeutic strategies against cancer.IGC researchers identify signals emitted by the tumor environment, which controls the migrating capacity of cancer cells. more
Antihypertensive drugs may protect against COVID-19 in heart patients  NEWS MEDICAL · 2 days
Common drugs used in high blood pressure, heart failure, and diabetic patients with kidney damage, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), could be protective in patients... more
FDA to trial malaria drugs Chloroquine and Hydroxychloroquine for COVID-19  NEWS MEDICAL · 2 days
The U.S. Food and Drug Administration (FDA) this week provided the necessary authorization for clinical trials of chloroquine and hydroxychloroquine for the treatment of the novel coronavirus. These... more
Total-body PET provides suitable images of antibodies up to 30 days after injection  NEWS MEDICAL · 2 days
Combining 89Zr-labeled antibodies with total-body positron emission tomography (PET) has extended the utility of novel total-body PET scanners, providing suitable images up... more
FDA nod for first experimental plasma therapy for COVID-19 in the U.S.  NEWS MEDICAL · 2 days
The coronavirus disease (COVID-19) global pandemic has rapidly spread across the globe, now affecting 180 countries and territories. The United States is the front... more
Stellenbosch University and AzarGen Biotechnologies join forces to tackle COVID-19  NEWS MEDICAL · 2 days
Stellenbosch University in South Africa and AzarGen Biotechnologies (Pty) Ltd, a South African biotechnology company focused on developing human therapeutic proteins using advanced genetic engineering and synthetic biology... more
Amyloid plaque formation causes brain tissue loss in animals  NEWS MEDICAL · 2 days
Amyloid plaque formation directly causes brain tissue loss in animals, but a drug called lithium reduces the life-shortening effects of this loss, shows a study published today in eLife. more
Combination of exercise and cell-aging drug could help people with chronic inflammatory myopathy  NEWS MEDICAL · 2 days
Exercise can only improve strength in muscle-degenerating diseases when a specific type of muscle cell ages, report a Hokkaido University researcher and... more
Wearable delivery device allows adults with type 2 diabetes to safely use affordable insulin therapy  NEWS MEDICAL · 2 days
Adults with type 2 diabetes requiring insulin therapy can safely achieve good blood sugar control using regular human... more
Hypothyroidism patients cite effectiveness of desiccated thyroid extract over standard therapy  NEWS MEDICAL · 3 days
Three in four hypothyroidism patients who chose desiccated thyroid extract (DTE) over the standard therapy said this option was more effective than other thyroid hormone medications,... more
Investigational oral form of treatment offers hope for adults with acromegaly  NEWS MEDICAL · 3 days
Adults who need medical maintenance treatment of the growth hormone disorder acromegaly respond well to an investigational oral form of the drug octreotide, investigators of the... more
New viable therapeutic strategy found for ER+ breast cancer  NEWS MEDICAL · 3 days
Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments. more
Thyroid hormone replacement therapy linked to higher risk of death in older adults  NEWS MEDICAL · 3 days
Thyroid hormone replacement therapy in older adults is associated with a higher risk of death compared with no treatment, a large study... more
FDA changes boost alcohol for sanitizer from ethanol makers  ABC NEWS · 3 days
The Food and Drug Administration has relaxed regulations on the types of alcohol that can be used for hand sanitizer during a shortage caused by high demand from the coronavirus... more
Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19  NEWS MEDICAL · 3 days
Cobra Biologics, an international CDMO for biologics and pharmaceuticals, and the Karolinska Institutet, one of the world’s leading medical universities, today announced... more
On Mars or Earth, biohybrid can turn carbon dioxide into new products  PHYS.ORG · 3 days
If humans ever hope to colonize Mars, the settlers will need to manufacture on-planet a huge range of organic compounds, from fuels to drugs,... more
Potential new method of breast cancer treatment using androgen receptor  NEWS MEDICAL · 3 days
Scientists may have discovered a new therapeutic approach to treat ER+ breast cancer using androgen receptor-stimulating drugs. more
Researchers reveal mechanism of trimming longer RNA transcripts to become micro RNA  PHYS.ORG · 3 days
A particular group of non-coding RNAs (ncRNAs) known as microRNAs (miRNAs) are ~22 nucleotide (nt) in length and play vital roles in diverse physiological... more
Wearable device lets patients with type 2 diabetes safely use affordable insulin option  SCIENCE DAILY · 3 days
Adults with type 2 diabetes requiring insulin therapy can safely achieve good blood sugar control using regular human insulin (RHI) in a... more
The placebo effect and psychedelic drugs: Tripping on nothing?  SCIENCE DAILY · 3 days
A new study suggests that, in the right context, some people may experience psychedelic-like effects from placebos alone. The researchers reported some of the strongest placebo effects on consciousness in... more
How to quickly and efficiently identify huge gene data sets to help coronavirus research  PHYS.ORG · 3 days
Thanks to the advancement of sequencing technology, it's possible to produce massive amounts of genome sequence data on various species.... more
Researchers discover molecule's unusual cell-killing mechanism  PHYS.ORG · 3 days
Soon after Jake Eaton joined the lab of Stuart Schreiber at the Broad Institute of MIT and Harvard in 2015, the postdoctoral researcher became intrigued by some wild theories being debated by his colleagues. The theories... more
Biochemists trap and visualize an enzyme as it becomes active  PHYS.ORG · 3 days
How do you capture a cellular process that transpires in the blink of an eye? Biochemists at MIT have devised a way to trap and visualize a vital... more
Phage capsid against influenza: Perfectly fitting inhibitor prevents viral infection  PHYS.ORG · 3 days
A new approach brings the hope of new therapeutic options for suppressing seasonal influenza and avian flu. On the basis of an empty and therefore non-infectious shell of... more
Understanding the novel coronavirus genome  NEWS MEDICAL · 3 days
The novel coronavirus emerged in December 2019 in Wuhan City, Hubei Province, in China, and since then, it has rapidly spread to over 170 countries across the globe. Our knowledge of the virus, now officially named severe acute... more
Ticagrelor therapy, without aspirin, can benefit patients with acute coronary syndrome  NEWS MEDICAL · 3 days
Patients with acute coronary syndrome (ACS) who stopped taking aspirin three months after the insertion of a coronary stent and then took the anti-platelet medication ticagrelor... more
Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder  NEWS MEDICAL · 3 days
The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first... more
New study helps identify drugs that are safe for treating COVID-19  NEWS MEDICAL · 3 days
A recent study has found that there is no evidence for or against the use of non-steroidal anti-inflammatory drugs such as ibuprofen for patients with COVID-19. more
Researchers develop chemically modified phage capsid that “stifles” influenza viruses  NEWS MEDICAL · 3 days
A new approach brings the hope of new therapeutic options for suppressing seasonal influenza and avian flu: On the basis of an empty - and therefore non-infectious -... more
UDCA treatment affects C. diff life cycle, reduces inflammatory response in mice  NEWS MEDICAL · 3 days
Researchers from North Carolina State University have found that a commonly used drug made from secondary bile acids can affect the life cycle of... more
Higher serum EPA levels from prescription fish oil associated with lower cardiovascular events  NEWS MEDICAL · 3 days
Higher levels of the omega-3 fatty acid eicosapentaenoic acid (EPA) found in the blood—and not a decrease in triglyceride levels as originally... more
Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal  NEWS MEDICAL · 3 days
An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following... more
TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients  NEWS MEDICAL · 3 days
Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk... more
'Living drug factories' could be used to achieve long-term treatment of chronic diseases  NEWS MEDICAL · 3 days
One promising way to treat diabetes is with transplanted islet cells that produce insulin when blood sugar levels get too low. more
Investigational drug vericiguat benefits patients with worsening heart failure  NEWS MEDICAL · 3 days
Patients with worsening heart failure and reduced ejection fraction who received the investigational drug vericiguat had a significantly lower rate of cardiovascular death or heart failure hospitalization compared with those... more
Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH  NEWS MEDICAL · 3 days
The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical... more
Trial delayed for Ohio doctor charged in deaths at hospital  ABC NEWS · 4 days
The murder trial of an Ohio doctor accused of ordering excessive painkiller doses for dozens of patients will be delayed due to coronavirus concerns more
Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma  NEWS MEDICAL · 4 days
Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year. more
Study helps to identify medications which are safe to use in treatment of COVID-19  SCIENCE DAILY · 4 days
A recent study has found that there is no evidence for or against the use of non-steroidal anti-inflammatory drugs such... more
Newly discovered enzyme “square dance” helps generate DNA building blocks  MIT · 4 days
MIT biochemists can trap and visualize an enzyme as it becomes active — an important development that may aid in future drug development. more
Artificial Intelligence Identifies Potential Anti-COVID-19 Drugs  SCI-NEWS.COM · 4 days
Scientists from Gero Pte. Ltd., Singapore, have used a deep neural network to search for host-target acting antivirals among experimental and approved drugs with... more
Research could open up new therapeutic strategies for some lung and kidney cancers  NEWS MEDICAL · 4 days
New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose... more
Revita DMR therapy has potential to transform lives of patients with poorly controlled type 2 diabetes  NEWS MEDICAL · 4 days
Patients with poorly controlled type 2 diabetes who underwent a novel, minimally invasive, endoscopic procedure called... more
Experimental drug could offer new treatment for people with chronic heart failure  NEWS MEDICAL · 4 days
An experimental drug recently concluded a successful third-phase clinical trial and could potentially offer a new treatment for about 300,000 Canadians who have worsening... more
“Living drug factories” might treat diabetes and other diseases  MIT · 4 days
Chemical engineers have developed a way to protect transplanted drug-producing cells from immune system rejection. more
Weakness in lung and kidney cancer cells could serve as therapeutic target  NEWS MEDICAL · 4 days
An important discovery about how some cancers rely on glucose to survive could lead to development of tumor-specific treatments. more
Pandemic bonds: The financial cure we need for COVID-19?  PHYS.ORG · 4 days
Countries around the world are taking unprecedented action to stem financial collapse due to COVID-19. Governments are acting as insurers of last resort, providing liquidity to both individuals and corporations... more
What takes so long? A behind-the-scenes look at the steps involved in COVID-19 testing  NEWS MEDICAL · 4 days
After a slow start, testing for COVID-19 has ramped up in recent weeks, with giant commercial labs jumping into the... more
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