Pharmaceuticals
Geneticists continue to unravel how genes impact drug use and addiction  SCIENCE DAILY · 3 hours
Research is revealing new insights into how genes impact drug use and addiction through a novel study of susceptibility to the effects of cocaine and methamphetamine... more
Potential breakthrough in understanding tumor dormancy  SCIENCE DAILY · 3 hours
Scientists may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a... more
Vermont attorney general sues owners of opioid manufacturer  ABC NEWS · 4 hours
Vermont Attorney General T.J. Donovan says he's filed suit against eight members of the family that owns the drug company that manufactures OxyContin, one of the drugs believed to be part of... more
CBD and CBD Oil: What Is It and Does It Really Work?  LIVE SCIENCE · 4 hours
CBD has become remarkably popular in recent years. But is it the cure-all people think it is? more
CBD May Reduce Drug Cravings in People with Heroin Addiction, Small Study Finds  LIVE SCIENCE · 6 hours
A small study suggests that the marijuana compound cannabidiol (CBD) may reduce cravings in those with heroin addiction. more
Study suggests exercise as new primary prescription for psychiatric patients  NEWS MEDICAL · 7 hours
When it comes to inpatient treatment of a range of mental health and mood disorders -- from anxiety and depression to schizophrenia, suicidality and acute psychotic episodes -- a new... more
Cancer: Using 3D to test personalized treatments in five days  SCIENCE DAILY · 10 hours
Researchers have devised a cell co-culture platform that reproduces a patient's tumor structure in 3D. The scientists can use it to test several drugs or their combinations at... more
Virtual clinical trial: Improving methadone dosage for drug users with TB to prevent withdrawal symptoms  NEWS MEDICAL · 12 hours
Drug users on methadone programs who contract tuberculosis should receive effective treatment while maintaining the correct level of... more
Dead cells disrupt how immune cells respond to wounds and patrol for infection  SCIENCE DAILY · 12 hours
Immune cells prioritize the clearance of dead cells overriding their normal migration to sites of injury. A research paves the way for... more
Owlstone Medical announces strategic collaboration with Actelion to improve lives of people with pulmonary hypertension  NEWS MEDICAL · 13 hours
Owlstone Medical, the global leader in Breath Biopsy® for applications in early disease detection and precision medicine today... more
Directed Systems awarded InnovateUK funding to develop clinical decision support software  NEWS MEDICAL · 13 hours
Pioneering software that enables anesthetists to make better decisions for high risk patients during surgery has been awarded InnovateUK funding. more
Plant discovery opens frontiers  PHYS.ORG · 13 hours
University of Adelaide researchers have discovered a biochemical mechanism fundamental to plant life that could have far-reaching implications for the multibillion dollar biomedical, pharmaceutical, chemical and biotechnology industries. more
Small molecule drug could be an effective strategy to treat glioblastoma  NEWS MEDICAL · 17 hours
A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be... more
Why Missouri’s the last holdout on a statewide Rx monitoring program  NEWS MEDICAL · 18 hours
Missouri retained its lonely title as the only state without a statewide prescription drug monitoring program — for the seventh year in a row — after... more
Opioid prescriptions drop sharply among state workers  NEWS MEDICAL · 19 hours
The agency that manages health care for California's massive state workforce is reporting a major reduction in opioid prescriptions, reflecting a national trend of physicians cutting back on the addictive drugs. more
People with benign skin condition willing to trade time, money to cure disorder  SCIENCE DAILY · 1 day
People with benign hyperpigmentation (the darkening or increase in the natural color of the skin), are willing to pay (WTP) nearly 14... more
Medical News Today: What to know about mood stabilizers  MNT · 1 day
Mood stabilizers, such as lithium, can help treat a range of conditions, including bipolar disorder. These drugs are often effective, but there are also some risks. Learn more here. more
What to know about mood stabilizers  MNT · 1 day
Mood stabilizers, such as lithium, can help treat a range of conditions, including bipolar disorder. These drugs are often effective, but there are also some risks. Learn more here. more
Benralizumab not effective reducing exacerbations in moderate to very severe COPD  SCIENCE DAILY · 1 day
New research shows that the asthma drug benralizumab failed to decrease annual COPD exacerbation rates for patients with moderate to very severe COPD, a history of... more
Key acid-activated protein channel identified  PHYS.ORG · 1 day
Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart attack, cancer and inflammation. The researchers believe the discovery... more
New method simplifies the search for protein receptor complexes, speeding drug development  PHYS.ORG · 1 day
For a drug to intervene in cells or entire organs that are not behaving normally it must first bind to specific protein receptors in... more
Cancer drug could be repurposed to provide treatment for brain aneurysms  SCIENCE DAILY · 1 day
An important class of drug used to treat cancer patients could be used to treat brain aneurysms, according to new research. more
Supreme Court sends dispute over Fosamax back to lower court  ABC NEWS · 1 day
The Supreme Court is sending a dispute between drugmaker Merck and patients who used its bone-strengthening drug Fosamax back to a lower court more
Stroke, cancer and heart disease: Key acid-activated protein channel  SCIENCE DAILY · 2 days
Researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart attack, cancer and... more
New drug could alleviate symptoms of rare musculoskeletal condition  NEWS MEDICAL · 2 days
A new study shows a drug developed in conjunction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than... more
Magnetically propelled MOFBOTs perform microrobotic drug delivery (w/video)  nanowerk · 2 days
By applying concepts developed in micro- and nanorobotics, researcherss demonstrate the controlled motion and delivery of cargo payloads embedded in metal-organic frameworks (MOFs). The helical MOF-based micromachine, propelled by artificial bacterial flagella... more
Researchers examine the protocol for treating aggressive prostate cancer  NEWS MEDICAL · 2 days
Treating an aggressive disease is always challenging but improving the way therapies are applied can benefit patients by giving them a better outcome. more
New project involves understanding link between opioid crisis and cancer  NEWS MEDICAL · 2 days
Jennifer Havens, Ph.D., professor of behavioral science in the University of Kentucky College of Medicine, faculty member in the Center on Drug and Alcohol Research and member of... more
Cancer drug could be used to treat brain aneurysms, shows research  NEWS MEDICAL · 2 days
An important class of drug used to treat cancer patients could be used to treat brain aneurysms, according to new research published this week. more
Study examines potential advantages and disadvantages of blister packaging for nursing homes  NEWS MEDICAL · 2 days
In blister packaging, a pharmacy (or a service provider commissioned by it) portions and packs the prescribed drugs of a patient according to weekdays... more
New tool provides standards for describing characteristics and use of cell therapies  NEWS MEDICAL · 3 days
Cell therapies including so-called "stem cells" are increasingly being marketed and used for the treatment of musculoskeletal disorders - despite questions about these treatments... more
Can Touching Fentanyl Really Kill You?  LIVE SCIENCE · 4 days
Myths about mere exposure to the drug don't match with what doctors know about opioid toxicity. more
Medical News Today: Augmentin (Amoxicillin/clavulanate potassium)  MNT · 4 days
Augmentin (amoxicillin/clavulanate potassium) is a prescription medication that’s used to treat infections caused by bacteria. It belongs to a class of drugs called penicillin antibiotics. Augmentin comes as an oral tablet and an oral liquid suspension.... more
Clinical trial improves treatment of genetic rickets  SCIENCE DAILY · 4 days
A new study shows a drug to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies. more
A new approach to targeting cancer cells  SCIENCE DAILY · 4 days
A research team has come up with a new approach to targeting cancer cells that circumvents a challenge faced by currently available cancer drugs. more
Dangerous pathogens use this sophisticated machinery to infect hosts  SCIENCE DAILY · 4 days
A detailed new model of a bacterial secretion system provides directions for developing precisely targeted antibiotics. more
Medical News Today: What to know about nitroglycerin  MNT · 4 days
Nitroglycerin is a drug that primarily treats a specific chest pain that doctors call angina. Learn about when they prescribe it, how it works to relieve angina, safe dosages, risks, and side... more
Dangerous pathogens use this sophisticated machinery to infect hosts  PHYS.ORG · 4 days
Gastric cancer, Q fever, Legionnaires' disease, whooping cough—though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.... more
'Smart' insulin could prevent hypoglycemia during diabetes treatment  SCIENCE DAILY · 4 days
Bioengineers have developed a new type of insulin that could help prevent hypoglycemia in people who use the drug to manage diabetes. more
Toy transformers and real-life whales inspire biohybrid robot  SCIENCE DAILY · 4 days
Researchers create a remote-controlled soft robot that can transform itself to conduct targeted drug delivery against cancer cells. more
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection  Science Magazine · 4 days
Infection with chikungunya virus (CHIKV) causes an acute illness characterized by fever, rash, and arthralgia. However, CHIKV infection can sometimes... more
B cells engineered to express pathogen-specific antibodies protect against infection  Science Magazine · 4 days
Effective vaccines inducing lifelong protection against many important infections such as respiratory syncytial virus (RSV), HIV, influenza virus, and Epstein-Barr virus (EBV) are not yet available despite decades... more
AI-powered 'knowledge engine' a game-changer for antibiotic resistance  PHYS.ORG · 5 days
A groundbreaking project to tackle one of the world's most pressing and complex health challenges—antimicrobial resistance (AMR)—has secured a $1 million boost. UTS will lead a consortium of 26 researchers from 14... more
‘Sham’ sharing ministries test faith of patients and insurance regulators  NEWS MEDICAL · 5 days
Sheri Lewis, 59, of Seattle, needed a hip transplant. Bradley Fuller, 63, of nearby Kirkland, needed chemotherapy and radiation when the pain in his jaw turned out to... more
Electron microscopy project could revolutionize the search for new drugs  NEWS MEDICAL · 5 days
The search for new drugs to combat diseases more effectively could be revolutionized through a new £30 million electron microscopy project. more
University of Virginia chemist identifies potential addiction-free pain reliever  NEWS MEDICAL · 5 days
An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse. more
Study may help identify patients at relapse risk after treatment for cocaine use disorder  NEWS MEDICAL · 5 days
A study conducted at the University of São Paulo in Brazil and described in an article published in the journal... more
Naturally occurring human antibody reveals hidden weakness in influenza virus  NEWS MEDICAL · 5 days
The ever-changing "head" of an influenza virus protein has an unexpected Achilles heel, report scientists funded by the National Institute of Allergy and Infectious Diseases, one of the... more
Dems push bill on health care, drug prices through House  ABC NEWS · 5 days
Democrats have pushed legislation buttressing the 2010 health care law and curbing prescription drug prices through the House more
The Latest: House Democrats OK bill boosting health care law  ABC NEWS · 5 days
Democrats have pushed legislation through the House that would buttress the 2010 health care law and curb prescription drug prices more
Dems push bill on Obamacare, drug prices toward House OK  ABC NEWS · 5 days
Democrats are pushing legislation buttressing the 2010 health care law and curbing prescription drug prices toward House passage more
Understanding neurotoxic side effects of CAR T-cell therapy  NEWS MEDICAL · 5 days
The recent advent of chimeric antigen receptor (CAR) T-cell therapy has revolutionized the clinical treatment of cancer. more
Medical News Today: What are the side effects of Adderall?  MNT · 5 days
Adderall is a stimulant drug that people with ADHD can take to relieve their symptoms. Adderall can have mild to severe side effects. Learn more here. more
Designing biological movement on the nanometer scale  SCIENCE DAILY · 5 days
Synthetic proteins have now been created that can move in response to their environment in predictable and tunable ways. These proteins can use their movement to disrupt lipid membranes in cells. They show promise... more
Could better tests help reverse the rise of drug-resistant infections?  SCIENCE DAILY · 5 days
Faster, more accurate tests for drug-resistant infections are hailed as a promising tool in the fight against antibiotic resistance, so much so that the US and Britain are... more
Constrained sialic acid donors enable selective synthesis of {alpha}-glycosides  Science Magazine · 5 days
Sialic acid is a sugar residue present in many biologically significant glycans of mammals, commonly as a terminal α-glycoside. The chemical structure of sialic acid, which features an anomeric center... more
Electron diffraction determines molecular absolute configuration in a pharmaceutical nanocrystal  Science Magazine · 5 days
Determination of the absolute configuration of organic molecules is essential in drug development and the subsequent approval process. We show that this determination is possible through electron diffraction... more
Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors  Science Magazine · 5 days
The ATP-binding cassette subfamily B member 1 (ABCB1) multidrug transporter P-glycoprotein plays a central role in clearance of xenobiotics in humans and is implicated in cancer... more
When science and politics collide: Support for enhancing FDA independence  PHYS.ORG · 5 days
Earlier this year, twin papers authored by seven former Food and Drug Administration commissioners, published by Health Affairs and the Aspen Institute on the same day, suggested that... more
Could better tests help reverse the rise of drug-resistant infections?  PHYS.ORG · 5 days
A growing number of infections—such as pneumonia, gonorrhea and tuberculosis—are becoming harder to treat, as bacteria evolve defenses against antibiotics faster than we can develop new drugs to... more
Recombinant insulin could potentially address key concerns about the lifesaving drug  NEWS MEDICAL · 5 days
A researcher from the University of Houston has created a form of recombinant insulin that could potentially address some of the biggest concerns about the lifesaving... more
Human antibody reveals hidden vulnerability in influenza virus  SCIENCE DAILY · 5 days
The ever-changing 'head' of an influenza virus protein has an unexpected Achilles heel, report scientists. The team discovered the structure of a naturally occurring human antibody that recognizes and disrupts a portion... more
Antibody responses vs. Ebola keep evolving in survivors, months after recovery  SCIENCE DAILY · 5 days
Antiviral antibodies produced by survivors of Ebola infection continue to evolve and improve after recovery, according to a study of immune responses in four people who... more
Chemists ID possible addiction-free pain reliever  PHYS.ORG · 5 days
An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse. This causes an economic burden of more than $78 billion per... more
Surprising research result: All immature cells can develop into stem cells  SCIENCE DAILY · 5 days
A new study challenges traditional knowledge of stem cell development. The study reveals that the destiny of intestinal cells is not predetermined, but instead determined by... more
Antibiotic treatment alleviates Alzheimer's disease symptoms in male mice  SCIENCE DAILY · 5 days
Researchers have demonstrated that the type of bacteria living in the gut can influence the development of Alzheimer's disease symptoms in mice. The study shows that, by altering the gut... more
Neurological Side Effects of CAR T-Cell Therapy Revealed  NEWS MEDICAL · 5 days
Researchers at Brigham and Women’s Hospital quantified the neurological symptoms associated with CAR T-cell therapy and found that 77 percent of patients receiving the treatment experienced at least one neurological side effect. more
Cancer drugs promote stem cell properties of colorectal cancer  SCIENCE DAILY · 5 days
Scientists have now discovered that a certain group of cancer drugs (MEK Inhibitors) activates the cancer-promoting Wnt signalling pathway in colorectal cancer cells. This can lead to the accumulation of... more
Notorious astrology doctors' 400-year-old case notes transcribed and released online  PHYS.ORG · 6 days
Simon Forman and his protégé Richard Napier were infamous in early 17th-century England for their apparent ability to diagnose and even cure all kinds of ailments – from... more
CRISPR catches out critical cancer changes: New drug target for multiple cancers  SCIENCE DAILY · 6 days
In the first large-scale analysis of cancer gene fusions, researchers used CRISPR to uncover which gene fusions are critical for the growth of cancer... more
Activation of gene promoters: Scientists discover basis of regulatory specificity  PHYS.ORG · 6 days
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could... more
Longer-acting, injectable HIV treatments on the horizon  NEWS MEDICAL · 6 days
An HIV diagnosis was once a death sentence, but now people who receive treatment survive for decades with the disease. Keeping the virus at bay usually requires taking a pill every day, which aside... more
Blood test can assess effectiveness of treatment in patients with skin cancer  NEWS MEDICAL · 6 days
Blood tests that track the amount of tumor DNA can - after only one month of drug therapy - detect how well treatment is... more
Repetitive transcranial magnetic stimulation improves working memory, study shows  NEWS MEDICAL · 6 days
Magnetic stimulation of the brain improves working memory, offering a new potential avenue of therapy for individuals living with Alzheimer's disease and other forms of dementia, according to new research... more
Researchers identify why lymphoma patients may become resistant to specific drug  NEWS MEDICAL · 6 days
With more targeted therapies being approved each year for cancer, the development of drug resistance to these agents is a growing concern. more
Judge orders FDA to speed up review of e-cigarettes  ABC NEWS · 6 days
A federal judge is ordering the Food and Drug Administration to begin reviewing e-cigarettes more
New drug could help treat neonatal seizures  SCIENCE DAILY · 6 days
A new drug that inhibits neonatal seizures in rodent models could open up new avenues for the treatment of epilepsy in human newborns. more
How cancer drug inhibits DNA repair in cancer cells  SCIENCE DAILY · 6 days
A cancer drug thought to be of limited use possesses a superpower of sorts: It is able to stop certain cancer cells from repairing their DNA in order to survive. more
Why lymphoma patients may become resistant to specific therapy  SCIENCE DAILY · 6 days
Researchers have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid leukemia. Their... more
New strategy of reprogramming regulatory T cells may improve cancer therapies  SCIENCE DAILY · 6 days
Therapies that harness the power of the immune system against cancer have made remarkable progress against certain tumors but still remain ineffective in most cancer patients.... more
Enzyme PHLPP2 could be a viable drug target for treating prostate cancer  SCIENCE DAILY · 6 days
Researchers propose a new druggable target that can put a damper on the spread of prostate cancer. Containing the threat at its origin organ... more
New drug could open up avenues for treatment of neonatal epilepsy  NEWS MEDICAL · 6 days
A new drug that inhibits neonatal seizures in rodent models could open up new avenues for the treatment of epilepsy in human newborns. more
New approach to identify faster, more effective TB drug treatment regimens  NEWS MEDICAL · 6 days
Tuberculosis is a potentially deadly though curable disease. Each year about 10 million people develop active cases, and 1.6 million people die. In addition, about 1.7... more
Jawless fish take a bite out of the blood-brain barrier  SCIENCE DAILY · 6 days
A jawless parasitic fish could help lead the way to more effective treatments for multiple brain ailments, including cancer, trauma and stroke. Researchers borrowed molecules from the immune... more
Prescribing fitness apps to help cancer survivors increase their physical activity levels  NEWS MEDICAL · 6 days
Fitness apps could be prescribed by clinicians to help patients recovering from cancer increase their physical activity levels, new research in the Journal of... more
[Research Articles] Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina  Science Magazine · 6 days
Retinal gene therapy with adeno-associated viral (AAV) vectors holds promises for treating inherited and noninherited diseases of the eye. Although clinical data... more
[Reviews] Advances in therapeutic applications of extracellular vesicles  Science Magazine · 6 days
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of the source cell. EVs act as important... more
'Striking' differences in rates of HIV/AIDS within African nations  SCIENCE DAILY · 6 days
Despite the rapid scale-up of antiretroviral therapy (ART) since 2000, HIV/AIDS is still the most common cause of death in sub-Saharan Africa, according to data from the Global Burden of... more
Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix  Science Magazine · 6 days
Diseases that lead to blood-brain barrier (BBB) disruption will pathologically expose normally inaccessible brain extracellular matrix (ECM) to... more
Multiplexed single-cell RNA-seq via transient barcoding for simultaneous expression profiling of various drug perturbations  Science Magazine · 6 days
The development of high-throughput single-cell RNA sequencing (scRNA-seq) has enabled access to information about gene expression in individual cells and... more
Medical News Today: Novel Alzheimer's drug passes first phase of human testing  MNT · 6 days
A drug that tackles toxic protein buildup in Alzheimer's disease in a novel way has passed phase 1 of clinical trials, which tests safety... more
Brain stimulation improves working memory in adults  SCIENCE DAILY · 6 days
Magnetic stimulation of the brain improves working memory, offering a new potential avenue of therapy for individuals living with Alzheimer's disease and other forms of dementia. more
Why Missouri’s the last holdout on a statewide Rx monitoring program
NEWS MEDICAL
AI-powered 'knowledge engine' a game-changer for antibiotic resistance
PHYS.ORG
DNA folds into a smart nanocapsule for drug delivery
PHYS.ORG
Bridge over coupled waters: Scientists 3-D-print all-liquid 'lab on a chip'
PHYS.ORG
Synthesizing Modified and Pharmaceutically Relevant Peptides
NEWS MEDICAL
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