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Fear of losing heritage drives Cherokee Nation opioid case
ABC NEWS Cherokee Nation officials say fear of losing the tribe's heritage is driving a lawsuit that alleges distributors and retailers of opioid medications have contributed to prescription opioid abuse within the... 11 hours
Study prompts new ideas on cancers’ origins
SCIENCE DAILY Cancer therapies often target cells that grow and divide rapidly, such as stem cells, but in studying how stomach cancers occur, researchers found that even when the stomach isn't able to make stem cells,... 1 day
Medical News Today: Ketamine 'rapid and effective' for reducing suicidal thoughts
MNT The anesthetic ketamine has shown promise as a rapid treatment for reducing suicidal thoughts in people with depression, a new study reveals. 2 days
Ketamine 'rapid and effective' for reducing suicidal thoughts
MNT The anesthetic ketamine has shown promise as a rapid treatment for reducing suicidal thoughts in people with depression, a new study reveals. 2 days
HKBU experts develop new generation of smart anti-cancer drug molecules
NEWS MEDICAL The toxic nature of chemotherapy poses a great challenge to clinical treatment of cancer. A team of scholars from the School of Chinese Medicine of Hong Kong Baptist... 2 days
Scientists use nanoparticles to fight Mucoviscidosis
NEWS MEDICAL Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination. 2 days
Survey: Experts consider hazards of antibiotic resistances to be high
NEWS MEDICAL According to a survey among researchers, it is difficult to quantify the true extent of the hazards of antibiotic resistances to humankind. 2 days
Rejected antibiotic candidate could be worth a second look, research finds
NEWS MEDICAL An antibiotic candidate compound shelved in the 1970s in favour of more worthwhile drugs could be worth a second look, new research has found. 2 days
Medical News Today: Hemophilia cure? Gene therapy trial shows dramatic results
MNT A year after gene therapy treatment, people with hemophilia A are showing normal levels of clotting factor and big reductions in bleeding. 2 days
Nanoparticles as a solution against antibiotic resistance?
SCIENCE DAILY Scientists have succeeded in developing an efficient method to treat mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination. First of all, the active particles need to have a certain... 2 days
To fight the catastrophic fires of the future, we need to look beyond prescribed burning
PHYS.ORG California is burning – a sentence we've heard far too often this year. Sydney is currently on bushfire... 3 days
Garlic and fluorine combination shows promise as drug therapy
PHYS.ORG There's a lot more to garlic than its distinctive odor and strong, pungent taste. 3 days
Researchers examine link between tumor mutational burden and response to immune checkpoint therapy
NEWS MEDICAL Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome. 3 days
Nanoparticles as a possible solution to antibiotic resistance
PHYS.ORG Around one in 3,300 children in Germany is born with mucoviscidosis. A characteristic of this illness is that one channel albumen on the cell surface is disturbed by mutations. Thus, the amount... 3 days
Researchers explore patient-doctor conversations, best practices linked to opioid tapering
NEWS MEDICAL Increased scrutiny of opioid prescribing for patients with chronic pain has led providers and healthcare organizations to consider opioid-dose reductions, known as tapering. 3 days
Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics
NEWS MEDICAL Cancer molecular testing can drive clinical decision making and help a clinician determine if a patient is a good candidate for a targeted therapeutic drug. 3 days
'Bet hedging' explains the efficacy of many combination cancer therapies
SCIENCE DAILY The efficacy of many FDA-approved cancer drug combinations is not due to synergistic interactions between drugs, but rather to a form of "bet hedging," according to a new... 3 days
Simulation model finds Cure Violence program and targeted policing curb urban violence
SCIENCE DAILY When communities and police work together to deter urban violence, they can achieve better outcomes with fewer resources than when each works in isolation,... 3 days
Genetic variations may help identify people at high-risk for chronic pain after surgery
NEWS MEDICAL Genetics may play a role in determining whether patients experience chronic pain after surgery, suggests a study published today in the Online... 3 days
Computational strategies overcome obstacles in peptide therapeutics development
PHYS.ORG New computational strategies reported this week in Science might help realize the promise of peptide-based drugs. Peptides are similar to protein molecules, but differ in their smaller size, structure and functions. 3 days
Coloring books make you feel better, but real art therapy much more potent
SCIENCE DAILY Many adult coloring books claim to be art therapy and can reduce negative feelings, but art therapists are significantly more impactful, a... 3 days
Forty years after first Ebola outbreak, survivors show signs they can stave off new infection
SCIENCE DAILY Survivors of the first known Ebola outbreak, which occurred in the Democratic Republic of the Congo in 1976,... 3 days
Comprehensive computational design of ordered peptide macrocycles
Science Magazine Mixed-chirality peptide macrocycles such as cyclosporine are among the most potent therapeutics identified to date, but there is currently no way to systematically search the structural space spanned by such compounds. Natural proteins do... 3 days
Single-stranded DNA and RNA origami
Science Magazine Self-folding of an information-carrying polymer into a defined structure is foundational to biology and offers attractive potential as a synthetic strategy. Although multicomponent self-assembly has produced complex synthetic nanostructures, unimolecular folding has seen limited progress. We describe a... 3 days
Out-of-sync brain waves may explain why we get forgetful as we age
Science Magazine Work suggests potential therapies for memory loss 3 days
Synthetic protein packages its own genetic material and evolves
SCIENCE DAILY Scientists have created computationally designed protein assemblies, that display some functions normally associated with living things, in the search for ways to transport therapeutic cargo into specific types of cells... 3 days
Scientists develop new, rapid pipeline for antimicrobials
SCIENCE DAILY Antibodies are proteins produced by the human immune system to ward off foreign invaders. Our bodies mount this defense rapidly, especially if they have seen the invader before, producing the needed antibody within days... 3 days
Deadly heart rhythm halted by noninvasive radiation therapy
SCIENCE DAILY Radiation therapy often is used to treat cancer patients. Now, doctors have shown that radiation therapy -- aimed directly at the heart -- can be used to treat patients with a life-threatening... 3 days
Research points to second chance for rejected antibiotic candidate
PHYS.ORG An antibiotic candidate compound shelved in the 1970s in favour of more promising drugs could be worth a second look, new research has found. 4 days
Lab-grown meat could let humanity ignore a serious moral failing
PHYS.ORG Lab-grown meat is being hailed as the solution to the factory farming of animals. The downside of factory farming for the cows, chickens and pigs themselves is obvious... 4 days
Groundbreaking gene therapy trial set to cure hemophilia
SCIENCE DAILY A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial. 4 days
Steroid study sheds light on long term side effects of medicines
SCIENCE DAILY Fresh insights into key hormones found in commonly prescribed medicines have been discovered, providing further understanding of the medicines' side effects. 4 days
Israeli drugmaker Teva to cut quarter of global work force
PHYS.ORG Teva Pharmaceutical Industries Ltd., the world's largest generic drugmaker, on Thursday said it would lay off 14,000 workers as part of a global restructuring meant to salvage its... 4 days
A new way to deliver mRNA genomes: Nucleocapsids with evolutionary properties
PHYS.ORG (Phys.org)—A team of researchers at the University of Washington has created microscopic assemblies for packaging genetic material that they call synthetic nucleocapsids. The team hopes the... 4 days
Designer proteins that package genetic material could help deliver gene therapy
PHYS.ORG If you've ever bought a new iPhone, you've experienced good packaging. 4 days
Telemedicine for addiction treatment? Picture remains fuzzy
NEWS MEDICAL When President Donald Trump declared the opioid epidemic a public health emergency, it came with a regulatory change intended to make it easier for people to get care. The declaration allows for doctors to... 4 days
Radiation therapy can be used to treat patients with life-threatening heart rhythm
NEWS MEDICAL Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation... 4 days
Scientists develop new, rapid pipeline for antimicrobials
PHYS.ORG With hospitals more often reaching for antibiotics of last resort to fight infections and recent Ebola and Zika outbreaks crossing borders like never before, the worldwide scientific community has been challenged with developing new... 4 days
FDA announces new approach for sharing updates on antibiotics, antifungal drugs to physicians
NEWS MEDICAL Today the U.S. Food and Drug Administration is announcing a new approach to get critical updates regarding antibiotics and antifungal drugs to... 4 days
Study: Living Lyme disease bacteria found months after antibiotic treatment
NEWS MEDICAL Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the US, today announced results of two papers published in the peer-reviewed journals PLOS ONE and... 4 days
Groundbreaking gene therapy trial brings cure for hemophilia closer
NEWS MEDICAL A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial led by the NHS in London. 4 days
Forty years later, Ebola survivors are still making antibodies to the lethal virus
Science Magazine Study of people who lived after 1976 outbreak may provide hope for combatting the disease 4 days
A metallopeptide targets and disrupts mitochondrial function in breast cancer stem cells
SCIENCE DAILY Killing malignant mitochondria is one of the most promising approaches in the development of new anticancer drugs. Scientists have now synthesized a copper-containing peptide... 4 days
Tailor-made protein combats several kinds of pathogenic bacteria
NEWS MEDICAL As resistance to existing antibiotics increases, new approaches to serious bacterial infections are needed. Now researchers at Lund University in Sweden, together with colleagues at the University of Massachusetts Medical School in the US,... 4 days
Steroid study provides new insights into medicines' side effects
NEWS MEDICAL Fresh insights into key hormones found in commonly prescribed medicines have been discovered, providing further understanding of the medicines' side effects. 4 days
Belgian researchers create transplantable artificial ovary prototype
NEWS MEDICAL Belgian researchers have taken important steps towards creating transplantable artificial ovaries. Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy. 4 days
Survey shows prevalence of diarrhea in people living with HIV
NEWS MEDICAL Napo Pharmaceuticals, Inc., a human health company developing and commercializing novel gastrointestinal prescription products from plants used traditionally in rainforest areas, and a wholly-owned subsidiary of Jaguar Health,... 4 days
Genetic study defies 'one-size-fits-all' approach to prescribing opioids for chronic pain
SCIENCE DAILY Researchers are assessing clinical and genetic characteristics of a large patient cohort suffering from chronic musculoskeletal pain and receiving prescription opioids. With this information, the multidisciplinary... 4 days
[Editors' Choice] Running interference on hemorrhagic fever
Science Magazine A siRNA-based therapy for Marburg viruses shows promise. 4 days
[Editors' Choice] A diet pill for critical illness weakness?
Science Magazine The serotoninergic drug Lorcaserin rescued motor neuron electrophysiological abnormalities in an animal model of critical illness–induced weakness. 4 days
[Research Articles] Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis
Science Magazine Persistent myofibroblast activation distinguishes pathological fibrosis from physiological wound healing, suggesting that therapies selectively inducing myofibroblast apoptosis could prevent progression... 4 days
Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies
NEWS MEDICAL A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer... 4 days
Autism therapy: Social behavior restored via brain stimulation
SCIENCE DAILY Scientists are examining the feasibility of treating autistic children with neuromodulation after a new study showed social impairments can be corrected by brain stimulation. 4 days
Few California retailers offer pharmacist-prescribed birth control, despite law
SCIENCE DAILY A new law took effect in California last year allowing pharmacists to prescribe birth control, but few of the state's pharmacies are actually offering this service, according to new research. 4 days
Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups
NEWS MEDICAL A study by researchers at Mayo Clinic's campus in Jacksonville, Florida has found that barriers to patients receiving... 4 days
Scientists develop new artificial ovary prototype
SCIENCE DAILY Researchers have taken important steps towards creating transplantable artificial ovaries. Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy. The research team... 4 days
Specially designed protein fights several species of bacteria
SCIENCE DAILY As resistance to existing antibiotics increases, new approaches to serious bacterial infections are needed. Now researchers have investigated one such alternative. 4 days
Reprogramming bacteria instead of killing them could be the answer to antibiotic resistance
PHYS.ORG Changing someone's genetic programming is easier than you might think. While techniques for altering DNA at the molecular level are becoming more... 4 days
Approval of gene therapies for two blood cancers led to an ‘explosion of interest’ in 2017
SCIENCE-NEWS The first gene therapies approved in the United States are treating patients with certain types of... 5 days
Discovery of new protein shape could impact cancer and neurodegenerative disease therapies
PHYS.ORG A Virginia Commonwealth University researcher has discovered a new conformation of a common protein group with links to cancer metastasis and neurodegenerative diseases. 5 days
A metallopeptide targets and disrupts mitochondrial function in breast cancer stem cells
PHYS.ORG Killing malignant mitochondria is one of the most promising approaches in the development of new anticancer drugs. Scientists from the UK have now synthesized... 5 days
Experts call for rigorous clinical trials in use of experimental fetal therapy
NEWS MEDICAL Citing uncertainties about the risks and benefits of an experimental therapy for fetuses whose kidneys do not develop, bioethicists at Johns Hopkins and a... 5 days
Children's Colorado and RxRevu partner to help prescribers better meet needs of pediatric patients
NEWS MEDICAL Children's Hospital Colorado (Children's Colorado) and RxRevu, the leader in prescription-decision support, are collaborating to help prescribers better meet the... 5 days
Faster, more accurate cancer detection using nanoparticles
SCIENCE DAILY Using light-emitting nanoparticles, scientists have invented a highly effective method to detect tiny tumors and track their spread, potentially leading to earlier cancer detection and more precise treatment. The technology could improve patient cure... 5 days
Epigenetic orchestrator of pancreatic cancer cells
SCIENCE DAILY Genetech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin. The study suggests that targeting this enzyme could make pancreatic cancer cells more... 5 days
A new weapon against bone metastasis?
SCIENCE DAILY A new antibody fights bone metastasis by undermining cancer's defense strategy and allowing chemotherapy to work. 5 days
Enhancing chemotherapy's efficiency against leukemia
SCIENCE DAILY Researchers have found a mechanism through which certain types of leukemia resist chemotherapy, revealing novel molecular targets to improve this therapy's efficiency. 5 days
Using 3D cell cultures to fight anti-cancer therapy resistance
SCIENCE DAILY An international research team has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer.... 5 days
Study reveals novel molecular targets to improve chemotherapy’s efficiency against leukemia
NEWS MEDICAL Researchers from Instituto de Medicina Molecular João Lobo Antunes have found a mechanism through which certain types of leukemia resist chemotherapy, thus revealing novel molecular targets... 5 days
Risks of manipulating the global thermostat
PHYS.ORG If someone offered you a magic pill that claimed to cure all health ailments, would you take it? Let's say you did. Perhaps you'd start eating pizza and ice cream for every meal, since proper nutrition... 5 days
Teaching antibiotics to be more effective killers
SCIENCE DAILY Research suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth. 5 days
New therapy can help schizophrenia sufferers re-engage socially
SCIENCE DAILY A new therapy aimed at helping young people suffering from schizophrenia to reconnect and engage with the world around them has had promising results, according to a new study. 5 days
Cystic fibrosis: Discovery of a key molecule for improving treatments
SCIENCE DAILY Researchers identify a promising avenue for improving treatments for people with cystic fibrosis. They found that adding molecules called quorum-sensing inhibitors to current drugs not only reduces bacterial... 5 days
WATCH: Family fights to find a cure after 2 children are diagnosed with fatal genetic disease
ABC NEWS A New York couple is calling on the pubic's help to raise awareness and funding for... 6 days
Experts tell Congress how to cut drug prices
NEWS MEDICAL The nation's most influential science advisory group will tell Congress today that the U.S. pharmaceutical market is not sustainable and needs to change. 6 days
Teaching antibiotics to be more effective killers
PHYS.ORG Research from the University of Illinois at Chicago suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth. 6 days
An overlooked epidemic: Older Americans taking too many unneeded drugs
NEWS MEDICAL Consider it America’s other prescription drug epidemic. For decades, experts have warned that older Americans are taking too many unnecessary drugs, often prescribed by multiple doctors, for dubious... 6 days
Novel compound inhibits mycomembrane biosynthesis and kills tuberculosis bacteria
NEWS MEDICAL Tuberculosis is one of the most widespread life-threatening infectious diseases. Not only does antibiotic resistance make treatment increasingly difficult, but the bacteria’s relatively impermeable mycomembrane also limits the effectiveness of... 6 days
Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease
NEWS MEDICAL Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To... 6 days
Anesthetics have the same effects on plants as they have on animals and humans
SCIENCE DAILY A new study has shown that plants react to anesthetics similarly to the way animals and humans do, suggesting plants... 6 days
Huntington's disease drug clears initial hurdles - raising hopes
NEWS MEDICAL Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the... 6 days
Study: Combination targeted therapy has high response rates in AML patients
NEWS MEDICAL Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response... 6 days
Anesthetics cause similar reaction in plants as they do in animals and humans
NEWS MEDICAL A new study published in Annals of Botany shows that plants react to anesthetics similarly to the way animals and humans do,... 6 days
Study provides new insights into mechanism of tumor survival in glioblastoma
NEWS MEDICAL A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting... 6 days
AML study reports high response rates with combination targeted therapy
SCIENCE DAILY Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up... 6 days
Researchers invent novel RNA nanotech to decorate exosomes for effective cancer therapy
PHYS.ORG A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA (siRNA) specifically to... 6 days
New method for more effective photothermal tumor therapy with infrared light
PHYS.ORG Nanorods made of bismuth sulfide kill tumor cells with heat when they are irradiated with near-infrared light (NIR). Chinese scientists are now making these weapons more... 6 days
Researchers ‘Paint’ World’s Smallest Mona Lisa
SCI-NEWS.COM A team of scientists at Caltech has created the smallest version of the Mona Lisa ever — out of DNA. The work is described... 6 days
Managing concerning behaviors when opioids are taken for chronic pain
SCIENCE DAILY Patients receiving long-term opioid therapy for chronic pain sometimes demonstrate challenging and concerning behaviors, such as using more opioid medication than prescribed or concomitant alcohol or drug use.... 6 days
Bacteria development marks new era in cellular design
SCIENCE DAILY Scientists have built a miniature scaffold inside bacteria that can be used to bolster cellular productivity, with implications for the next generation of biofuel production. Because there is a growing need for... 6 days
Does prescription opioid use by one household member increase risk of prescribed use in others?
SCIENCE DAILY Living in a household with a prescription opioid user may be associated with increased risk of prescription opioid... 6 days
Powerful new method for microbiome analysis developed
SCIENCE DAILY A new approach can identify antibiotic resistance and virulence markers missed by conventional techniques, report scientists. 6 days
Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer
NEWS MEDICAL An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures... 6 days
Yeast can be engineered to create protein pharmaceuticals
SCIENCE DAILY It took several years, but a research team has finally succeeded in mapping out the complex metabolism of yeast cells. The breakthrough means a huge step forward in the potential to more... 6 days
New, more easily administered therapies offer benefits for bleeding and clotting disorders
NEWS MEDICAL In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits... 6 days
Use of chemotherapy for early stage breast cancer declining, study says
SCIENCE DAILY A study of nearly 3,000 women with early stage breast cancer indicates a recent, significant decline in the use of chemotherapy despite the lack of any... 6 days
Global CAR T therapy trial shows high rates of durable remission for non-Hodgkin's lymphoma
SCIENCE DAILY In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah™... 6 days
Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia
NEWS MEDICAL University of North Carolina Lineberger Comprehensive Cancer Center researchers report that pairing an immunotherapy drug with chemotherapy proved beneficial for some patients with acute... 6 days
Study indicates decline in use of chemotherapy for early stage breast cancer patients
NEWS MEDICAL A study of nearly 3,000 women with early stage breast cancer indicates a recent, significant decline in the use of chemotherapy despite... 6 days
Could Probiotics Protect Kids From A Downside Of Antibiotics?
NPR
New way to form bioactive spider silk for medical use
PHYS.ORG