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Researchers working towards developing computer model for predicting heart health
NEWS MEDICAL Picture this: you're battling heart failure and meeting with your doctor to discuss treatment. Before prescribing anything, the doctor pulls up a virtual model of your heart on... 2 hours
New study shows possibility of battling opioid addiction in primary care
NEWS MEDICAL For many of the 2 million Americans addicted to opioids, getting good treatment and getting off prescription painkillers or heroin may seem like a far-off dream. 3 hours
Resolving traffic jams in human ALS motor neurons
SCIENCE DAILY A team of researchers used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic... 5 hours
New examination of occupational licensing contradicts decades of research
SCIENCE DAILY From doctors to engineers to carpet layers to massage therapists, more than one in three Americans is required to hold a license to work in their occupation. Broad consensus among researchers... 6 hours
Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients
NEWS MEDICAL From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in... 6 hours
New examination of occupational licensing contradicts decades of research
PHYS.ORG From doctors to engineers to carpet layers to massage therapists, more than one in three Americans is required to hold a license to work in their occupation. Broad consensus among researchers... 10 hours
Scientists receive critical funding to study treatments for three deadly cancers
NEWS MEDICAL Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of... 10 hours
HIV infection, even with antiretroviral therapy, appears to damage a growing child's brain
SCIENCE DAILY One of the largest and best-documented trials of children receiving early antiretroviral therapy -- the CHER clinical trial in South Africa --... 10 hours
Study could pave way for more effective cancer therapies
NEWS MEDICAL Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism, which normally prevent an excessive immune response.... 10 hours
Medical News Today: Type 2 diabetes: Blood sugar pill shows promise
MNT In a 26-week phase II clinical trial for type 2 diabetes patients, glycemic control using semaglutide in pill form was better than using a placebo. 13 hours
Novel mechanism of resistance to anti-cancer drugs
SCIENCE DAILY Investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings suggest a strategy for overcoming this resistance. 15 hours
On back roads of Appalachia’s coal country, mental health services are as rare as jobs
NEWS MEDICAL Every other month, Tanya Nelson travels 32 miles from the heart of Appalachia's coal country for an appointment... 16 hours
Mixed ad appeals lead to high medication empowerment among patients, study reveals
NEWS MEDICAL Autumn is flu season and that means it is high season for pharmacies selling over-the-counter cold and flu remedies. Those who aren't reminded by... 16 hours
The importance of asymmetry in bacteria
PHYS.ORG New research published in Nature Microbiology has highlighted a protein that functions as a membrane vacuum cleaner and which could be a potential new target for antibiotics. 17 hours
Researchers identify strategies to mitigate disturbed axonal transport in ALS patients
NEWS MEDICAL A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found... 17 hours
Cascade of costs could push new gene therapy above $1 million per patient
NEWS MEDICAL Outrage over the high cost of cancer care has focused on skyrocketing drug prices, including the $475,000 price tag for the country's... 18 hours
Clues to the innate drug resistance of a cocoa-fermenting pathogen
PHYS.ORG At first glance, the yeast Candida krusei seems as innocuous as microbes come: it's used for fermenting cocoa beans and gives chocolate its pleasant aroma. But it's increasingly... 19 hours
Using AFM to study cell mechanics and function
NEWS MEDICAL My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering... 20 hours
Scientists discover new non-genetic cause of resistance to anti-cancer therapies
NEWS MEDICAL The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States. 1 day
Wake Forest Baptist scientists win grant to develop more effective treatments for brain cancer
NEWS MEDICAL Glioblastoma is the most aggressive cancer that originates in the brain. Current therapies can slow the disease, but more often... 1 day
Magic mushrooms chemical Psilocybin for treatment of hard-to treat depression
NEWS MEDICAL A new study from UK has found efficacy of psilocybin – a chemical found in “magic mushrooms”, in severe depression. The study involved 19 patients with severe depression.... 1 day
Clues to the Innate Drug Resistance of a Cocoa-Fermenting Pathogen
SCIENCE DAILY At first glance, the yeast Candida krusei seems as innocuous as microbes come: it’s used for fermenting cocoa beans and gives chocolate its pleasant aroma. But it’s increasingly... 1 day
New online tool offers opioid prescribing recommendations after surgery
NEWS MEDICAL How many prescription pain pills should a patient receive after breast cancer surgery? Or a hernia repair? Or a gallbladder removal? 1 day
Researchers Uncover New Antibiotic Resistance Genes
SCI-NEWS.COM Chalmers University of Technology Professor Erik Kristiansson and co-authors have identified over 70 new metallo-β-lactamase genes that make bacteria resistant to last-resort antibiotics. “Metallo-β-lactamases... 1 day
Report sheds light on global market for infectious disease immunoassays
NEWS MEDICAL Kalorama Information says that infectious disease immunoassays beat the IVD market and the overall IVD market in terms of revenue growth. Immunoassays are tests that are based on... 1 day
How many opioid painkillers do surgery patients need? New prescribing recommendations unveiled
SCIENCE DAILY Surgeons performing 11 common operations can turn to a free new prescribing tool based on data about how many opioid painkillers patients across Michigan... 2 days
Neutrons observe vitamin B6-dependent enzyme activity useful for drug development
SCIENCE DAILY Scientists have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria and... 2 days
Scientists identify biomarker for progression, drug response in brain cancer
SCIENCE DAILY Scientists have reported results from a glioblastoma study in which they validated a biomarker indicative of a patient's prognosis and likely response to specific therapies. 2 days
Medical News Today: Dietary supplement may help to prevent seizures
MNT Researchers suggest that glucosamine, a dietary supplement, may help to reduce brain cell excitability, bringing us closer to a new therapy for epilepsy. 2 days
Neutrons observe vitamin B6-dependent enzyme activity useful for drug development
PHYS.ORG Scientists at the Department of Energy's Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs... 2 days
Dietary supplement may help to prevent seizures
MNT Researchers suggest that glucosamine, a dietary supplement, may help to reduce brain cell excitability, bringing us closer to a new therapy for epilepsy. 2 days
Endogenous infection marker can help guide antibiotic use
NEWS MEDICAL The endogenous infection marker procalcitonin can help to guide the use of antibiotics when treating infections. The course of antibiotic therapy is shortened, and its side effects and mortality rate also decrease,... 2 days
Stunner on birth control: Trump’s moral exemption is geared to just 2 groups
NEWS MEDICAL Few people were surprised last week when the Trump administration issued a rule to make it easier for some religious employers to... 2 days
Investigating new cancer therapy candidates with live-cell imaging
NEWS MEDICAL There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs... 2 days
Researchers to investigate cellular changes leading to development of glioblastoma
NEWS MEDICAL Glioblastoma is the most common of malign brain tumors in adults, and it currently has no cure. Now a research team led by Dr Claudia Barros, from the... 2 days
New antibiotic resistance genes found
SCIENCE DAILY Researchers have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA. 2 days
A range of substances with antitumor properties synthesized
PHYS.ORG Scientists from RUDN University have synthesized a number of new cytotoxic substances that can damage cells. The results of the study could be used in cancer therapy. The compounds were obtained by... 2 days
Wildlife in the ditches need a detox cure
PHYS.ORG When it's raining on the roads, slopes of road dust and contaminants drain into the trenches. What impact does it have on wildlife living by the road? 2 days
Mindfulness Apps Aim To Help People Disconnect From Stress
NPR Finding inner calm hard to come by? Some people use their device obsession to help them disconnect. The apps aren't a quick fix, therapists say, but might help you stick... 2 days
Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response
NEWS MEDICAL Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions including Colorado State University and Fred Hutchinson Cancer Center reported... 2 days
New antibiotic resistance genes found
PHYS.ORG Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA and the... 2 days
Researchers identify several previously unknown antibiotic resistance genes
NEWS MEDICAL Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. 2 days
FDA advisory committee vote 16-0 for first even gene therapy for rare blindness
NEWS MEDICAL A panel of advisors to the United States Food and Drug Administration (FDA) has voted unanimously in favor of an experimental gene... 2 days
Doctor's research could buy time for snake bite victims
ABC NEWS A researcher at the University of Arizona is experimenting with a new therapy to help treat rattlesnake bites 2 days
A dietary supplement dampens the brain hyperexcitability seen in seizures or epilepsy
SCIENCE DAILY Researchers have found that inducing a biochemical alteration in brain proteins via the dietary supplement glucosamine was able to rapidly dampen that pathological hyperexcitability... 4 days
Research aims to raise awareness of higher rate of testicular cancer in patients with DS
NEWS MEDICAL Research by Jue Wang, MD, at the University of Arizona Cancer Center at Dignity Health St. Joseph's Hospital... 4 days
Dietary supplement could be promising therapeutic target for seizure disorders
NEWS MEDICAL Seizure disorders -- including epilepsy -- are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability. 4 days
Researchers develop new ‘visual biofeedback’ system for speech therapy
NEWS MEDICAL A team of researchers in the GIPSA-Lab and at INRIA Grenoble Rhône-Alpes has developed a system that can display the movements of our own tongues in real time. 4 days
MTSA expands efforts to fight against national opioid epidemic
NEWS MEDICAL Middle Tennessee School of Anesthesia announced it is expanding efforts to educate Certified Registered Nurse Anesthetists on treatment options that reduce or eliminate the need for opioids during and after... 4 days
Augmented tongue ultrasound for speech therapy
SCIENCE DAILY Researchers have developed a system that can display the movements of our own tongues in real time. These movements are processed by a machine learning algorithm that controls an 'articulatory talking head.' This avatar shows the... 5 days
Cold therapy may be effective at controlling cancer treatment side effects
SCIENCE DAILY A new study finds that cryotherapy, specifically having chemotherapy patients wear frozen gloves and socks for 90-minute periods, is useful for preventing symptoms of neuropathy. 5 days
Uncovering origins of developmental brain disorders could eventually help treat seizures
SCIENCE DAILY New research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some children with autism. 5 days
Wildlife in the ditches need a detox cure
SCIENCE DAILY When it's raining on the roads, slops of road dust and contaminants drain into the road trenches. What does it do to wildlife living by the road? 5 days
FDA experts offer a unanimous endorsement for pioneering gene therapy for blindness
Science Magazine Agency expected to announce its verdict on company’s gene therapy by early 2018 5 days
Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome
NEWS MEDICAL Rettsyndrome.org is pleased to share that Neuren Pharmaceuticals, today, after meeting with the FDA, will conduct a Phase 3 clinical... 5 days
Local anesthesia before inserting venous cannula clearly reduces sensation of pain
NEWS MEDICAL Patients who are given a local anesthetic before having a venous cannula inserted have a clearly reduced sensation of pain when larger gauge cannulas are used.... 5 days
augmented tongue ultrasound for speech therapy Augmented tongue ultrasound for speech therapy
PHYS.ORG VIDEO A team of researchers in the GIPSA-Lab (CNRS/Université Grenoble Alpes/Grenoble INP) and at INRIA Grenoble Rhône-Alpes has developed a system that can display the movements of tongues in real time. Captured using an ultrasound probe placed... 5 days
How molecular riboswitches work in bacteria
PHYS.ORG Many bacteria have molecular control elements via which they can switch genes on and off. These riboswitches also open up new options in the development of antibiotics or the detection and decomposition of environmental toxins. Researchers... 5 days
AAPM&R endorses Perioperative Surgical Home model of care
NEWS MEDICAL The American Society of Anesthesiologists' Perioperative Surgical Home model of care's ability to significantly improve patient care, quality and reduce costs, has been endorsed by the American Academy of Physical Medicine and... 5 days
USC discovery may one day lead to new therapies for liver cancer
NEWS MEDICAL A Keck School of Medicine of USC research team has identified how cancer stem cells survive. This finding may one day lead to new... 5 days
How switches work in bacteria
SCIENCE DAILY Many bacteria have molecular control elements, via which they can switch on and off genes. These riboswitches also open up new options in the development of antibiotics or for the detection and decomposition of environmental toxins. Researchers have... 5 days
Millions die suffering amid global opioid gap, report says
ABC NEWS Report finds millions die suffering in part because of a global disparity that leaves many poor countries without opioid painkillers 5 days
Research findings could pave way to new therapies for treating seizures and autism
NEWS MEDICAL Recent research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some... 5 days
FDA Panel Endorses Gene Therapy For A Form Of Childhood Blindness
NPR Food and Drug Administration advisers unanimously recommended that the agency approve the first gene therapy for an inherited disease — a rare defect that causes blindness... 5 days
Life, death, and antibodies
Science Magazine 5 days
In a first for wearable optics, researchers develop stretchy fiber to capture body motion
PHYS.ORG The exciting applications of wearable sensors have sparked a tremendous amount of research and business investment in recent years. Sensors... 6 days
Studies advance methods to avert toxicity that can accompany immunotherapy
SCIENCE DAILY Two new papers provide the most comprehensive data yet reported on side effects of the emerging cancer immunotherapy strategy known as CAR T-cell therapy. 6 days
Researchers explore ways to remove antibiotics polluting lakes and rivers
PHYS.ORG Pharmaceuticals, including antibiotics, are an increasingly common pollutant in water systems, said Catherine Hui Niu, associate professor in the Department of Chemical and Biological Engineering at the University... 6 days
A method to screen unknown molecules of coral reefs for their therapeutic potential
PHYS.ORG Coral reefs harbor an incredible diversity of life, both sea creatures we can see and microbial life that we cannot. These organisms... 6 days
Discovery of peripheral neuropathy cause suggests potential preventive measures
SCIENCE DAILY In discovering how certain chemotherapy drugs cause the nerve damage known as peripheral neuropathy, researchers have found a potential approach to preventing this common and troublesome side effect of cancer... 6 days
Study provides detailed characterization of neurotoxicity arising from CD19 CAR T-cell therapy
NEWS MEDICAL New potential biomarkers and a novel algorithm could help identify patients at increased risk of suffering from severe neurotoxicity after receiving CD19 CAR T-cell... 6 days
Researchers find potential approach to prevent peripheral neuropathy
NEWS MEDICAL In discovering how certain chemotherapy drugs cause the nerve damage known as peripheral neuropathy, researchers at Dana-Farber Cancer Institute have found a potential approach to preventing this common and troublesome side effect... 6 days
Fundamental discovery may open potential for new types of cancer drugs
NEWS MEDICAL Many approved cancer therapies target a protein called epidermal growth factor receptor (EGFR) that regulates many crucial cellular processes and can speed the proliferation of tumor... 6 days
CUMC researchers discover ‘cell of origin’ for esophageal cancer
NEWS MEDICAL Columbia University Medical Center researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin"... 6 days
New Gene Therapy for Blindness: How Does It Work?
LIVE SCIENCE A new gene therapy may soon be approved to treat a rare genetic form of vision loss and blindness. But how does it work? 6 days
An engineer's guide to the embryo
PHYS.ORG In roughly 48 hours, the single cell of the fertilized frog egg will undergo dramatic change to develop vital body parts like muscles, a skeleton, eyes, a heart, and a tadpole tail. Scientists have been studying... 6 days
Epidurals don’t slow labor, study shows
SCIENCE DAILY Research has demonstrated that epidural medication had no effect on the duration of the second stage of labor, normal vaginal delivery rate, incidence of episiotomy, the position of the fetus at birth or any other measure... 6 days
Despite effectiveness women remain skeptical of hormones at menopause -- what's the problem?
SCIENCE DAILY Women today have more options than ever before for treating their menopause symptoms, although hormone therapy still ranks as the most effective... 6 days
Confusion about long-term treatment of osteoporosis clarified
SCIENCE DAILY Osteoporosis is a common disorder among postmenopausal women which results in an increased risk of fractures. While several therapies improve bone strength and reduce the risk of spine and hip fracture, there is no... 6 days
Hormone therapy may benefit migraine sufferers without increased risk of heart disease
SCIENCE DAILY Migraine headaches are common among women, but due to various health risks can be challenging to treat in the elderly. While hormone therapy is... 6 days
Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis
Science Magazine Combinations of three or more drugs are used to treat many diseases, including tuberculosis. Thus, it is important to understand how synergistic or antagonistic drug interactions... 6 days
Increased weight gain by C-section: Functional significance of the primordial microbiome
Science Magazine Epidemiological evidence supports a direct association between early microbiota impact—including C-section—and obesity. We performed antibiotic-free, fostered C-sections and determined the impact on the early microbiota and... 6 days
[Editors' Choice] Less is more for anticancer therapy combinations
Science Magazine Withdrawal of MAPK inhibition sensitizes cancer cells to DNA repair–targeting drugs. 6 days
[Research Articles] High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice
Science Magazine Protecting the heart after an acute coronary syndrome is a key therapeutic goal to support cardiac... 6 days
[Research Articles] Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1
Science Magazine Targeted genome editing in hematopoietic stem/progenitor cells (HSPCs) is an attractive strategy... 6 days
[Research Articles] An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target
Science Magazine Interleukin (IL)–36α, IL-36β, and IL-36 are... 6 days
New Therapy Halts Rare Brain Disease Depicted in 'Lorenzo's Oil'
LIVE SCIENCE Doctors have successfully suppressed a rare brain disease that typically strikes young boys, by using a novel type of therapy that alters a patient's genes. 7 days
Web-based therapies increase likelihood of people with severe mental illness finding work
NEWS MEDICAL Patients living with severe mental illness are being helped to return to work courtesy of new research from Sydney's Westmead Institute for Medical Research. 7 days
Predatory bacteria: The quest for a new class of antibiotics
SCIENCE DAILY Researchers take one step forward toward understanding and genetically manipulating B. bacteriovorus, a type of bacteria with promising potential use as a living antibiotic. 7 days
Doctors need a nudge to reduce antibiotic prescriptions, study finds
SCIENCE DAILY An update to a behavioral economics study on clinicians' prescriptions of antibiotics showed that the clinicians may, without long-term interventions, return to bad prescription habits. 7 days
Gel to fight rheumatoid arthritis
SCIENCE DAILY A new potentially therapeutic gel has been developed, which detects nitric oxide, absorbs excess fluids and delivers drugs. 7 days
A specific protein regulates the burning of body fat to generate heat
SCIENCE DAILY Scientists have identified a protein that holds promise as a target for therapies to reduce obesity. They have demonstrated that MKK6 controls the conversion... 7 days
Scientists develop machine-learning method to predict the behavior of molecules
SCIENCE DAILY A team of scientists has come up with a machine-learning method that predicts molecular behavior, a breakthrough that can aid in the development of pharmaceuticals and the design... 7 days
Scientists develop potentially therapeutic gel, which detects nitric oxide, absorbs excess fluids and delivers drugs
PHYS.ORG IBS scientists at the Center for Self-Assembly and Complexity, within the Institute for Basic Science (IBS), invented a... 7 days
Predatory bacteria—the quest for a new class of antibiotics
PHYS.ORG In 2016, the World Health Organization named antibiotic resistance as "one of the biggest threats to global health, food security, and development today." The announcement cited a growing list of... 7 days
Scientists identify protein as potential therapeutic target to fight against obesity
NEWS MEDICAL Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified a protein that holds promise as a target for therapies to reduce obesity. 7 days
Beyond Birth Control: 5 Conditions 'The Pill' Can Help Treat
LIVE SCIENCE Birth control medications are used for reasons that go far beyond simply preventing pregnancy. 7 days
Study examines effects of removing behavioral interventions on inappropriate antibiotic prescribing
NEWS MEDICAL In the 12 months after removing behavioral interventions, inappropriate antibiotic prescribing for acute respiratory infections increased relative to control practices, according to a study published by... 7 days
Scientists develop machine-learning method to predict the behavior of molecules
PHYS.ORG An international, interdisciplinary research team of scientists has come up with a machine-learning method that predicts molecular behavior, a breakthrough that can aid in the development of pharmaceuticals... 7 days
Novel midday bright light therapy decreases symptoms of depression in bipolar patients
NEWS MEDICAL Daily exposure to bright white light at midday significantly decreased symptoms of depression and increased functioning in people with bipolar disorder, a recent Northwestern... 7 days
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Augmented tongue ultrasound for speech therapy
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