Does Parkinson's disease (PD) start in the brain or the gut? In a new contribution, scientists hypothesize that PD can be divided into two subtypes: gut-first, originating in the peripheral nervous system (PNS) of the gut and spreading to the brain; and brain-first, originating in the brain, or entering the brain via the olfactory system, and spreading to the brainstem and peripheral nervous system.... SCIENCE DAILY · 2 weeks
Does Parkinson's disease start in the brain or gut?  NEWS MEDICAL · 2 weeks
Does Parkinson's disease start in the brain or the gut? In a new contribution published in the Journal of Parkinson's Disease, scientists hypothesize that PD can be divided into two... more
What do we know about the gut microbiota in Parkinson's disease?  SCIENCE DAILY · 1 week
Since the discovery that the gut microbiome may play a role in the development of Parkinson's disease (PD), this fresh scientific approach has produced varying results.... more
New recommendations aim to improve outcomes of Parkinson's disease patients  NEWS MEDICAL · 1 week
Since the discovery that the gut microbiome may play a role in the development of Parkinson's disease (PD), this fresh scientific approach has produced varying results. In this... more
Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease  NEWS MEDICAL · 1 week
In neurodegenerative conditions like Parkinson's disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists... more
New insights into how immune system and inflammation play a role in PD  NEWS MEDICAL · 5 days
Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction... more
Targeting the formation of alpha-synuclein aggregates may slow Parkinson's progression  NEWS MEDICAL · 5 days
Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease. more
Could improving the brain’s waste disposal system help prevent Parkinson’s and Alzheimer’s?  NEWS MEDICAL · 2 weeks
A new partnership between two leading medical research charities has launched today to explore how improving the brain’s waste disposal system could be the... more
The pathway to Parkinson's takes a surprising twist  SCIENCE DAILY · 1 week
A new study finds that neurons affected in Parkinson's disease can shut down without fully dying, allowing them to also switch off neighboring cells. The findings might give scientists a better understanding... more
Gut instincts: Researchers discover first clues on how gut health influences brain health  SCIENCE DAILY · 4 weeks
New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time. more
Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning  NEWS MEDICAL · 4 weeks
A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the... more
SleepFit app can help monitor motor symptoms in patients with Parkinson's disease  NEWS MEDICAL · 7 days
In order to optimally treat motor symptoms in patients with Parkinson's disease (PD), it is necessary to have a good understanding of their severity... more
Scientists propose new theory of Parkinson's disease  MNT · 7 days
In a new review of the evidence, scientists propose two main types of Parkinson's, depending on which part of the nervous system the disease originates in. more
Parkinson's Foundation and Parkinson's UK form new partnership  NEWS MEDICAL · 7 days
Each year, Parkinson's UK, their supporters and partners invest more than £4 million into the Parkinson's Virtual Biotech to rapidly develop and test the most promising research findings with the aim of... more
Medical News Today: Scientists propose new theory of Parkinson's disease  MNT · 7 days
In a new review of the evidence, scientists propose two main types of Parkinson's, depending on which part of the nervous system the disease originates in. more
Researchers evaluate potential of FMT, pre- and probiotics to treat Parkinson's patients  NEWS MEDICAL · 4 days
Constipation is a common complaint in patients with Parkinson's disease. Fecal microbiome transplantation and pre- and probiotics are potential options for treating constipation and... more
A possible gut-brain connection to 'chemo brain'  SCIENCE DAILY · 4 weeks
To test the possible relationship between the gut and chemo brain, a lab is examining chemo's effects on mice whose guts have been manipulated before treatment. One experiment involves feeding the mice antibiotics. The... more
Scientists identify new mechanism for the development of Parkinson's disease  NEWS MEDICAL · 7 days
An international research team including scientists from the University of Cologne have identified a new mechanism for the development of Parkinson's disease, which could prove to be the... more
New home-based app to better monitor Parkinson's disease  SCIENCE DAILY · 7 days
In order to optimally treat motor symptoms in patients with Parkinson's disease (PD), it is necessary to have a good understanding of their severity and daily fluctuations. A report describes how a... more
Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases  NEWS MEDICAL · 4 weeks
DJ-1 is well known as an important target for the treatment of a number of diseases such as Parkinson's disease. Cantabio has been developing novel small... more
Sugar-coating proteins can help us understand brain disease  SCIENCE DAILY · 2 weeks
Researchers have developed a new way to tag proteins in human cells with a small sugar molecule called O-GlcNAc. The exact role played by O-GlcNAc remains a mystery but the molecule is... more
New approach holds great potential to track tremor severity in Parkinson's patients  NEWS MEDICAL · 3 weeks
One of the hallmarks of Parkinson's disease (PD) is tremors. This involuntary movement disorder reduces quality of life by interrupting patients' activities such as... more
Targeting one gut bacterium may treat alcoholic liver disease  MNT · 3 days
Scientists have successfully eradicated alcoholic liver disease in mice using a combination of viruses that target a certain toxin-releasing gut bacterium. more
Medical News Today: Targeting one gut bacterium may treat alcoholic liver disease  MNT · 4 days
Scientists have successfully eradicated alcoholic liver disease in mice using a combination of viruses that target a certain toxin-releasing gut bacterium. more
Sleep protects the brain against Alzheimer’s by washing it  NEWS MEDICAL · 3 weeks
Researchers have found that when in deep sleep, the brain waves within can start off a cleaning system within the brain that can protect it against Alzheimer’s and other neurodegenerative... more
Starvation halts brain development, but hungry cells jump-start growth when food becomes available  SCIENCE DAILY · 4 weeks
In tadpole research that holds potential for prenatal health and brain injury, scientists identify cellular workings that stop and restart early brain... more
Unique brain changes in people with Huntington's disease  SCIENCE DAILY · 4 weeks
The part of the brain that selectively degenerates in people with Huntington's disease (HD), called the striatum, is almost entirely destroyed in the late stages of the disease. Brain samples from mutant... more
Discovery may help derail Parkinson's 'runaway train'  SCIENCE DAILY · 3 weeks
Researchers have discovered a new enzyme that inhibits the LRRK2 pathway. Mutations of the LRRK2 gene are the most common cause of genetic Parkinson's disease. The enzyme they found - called PPM1H - has... more
Molecular processes underlying communication between gut microbes and brain cells revealed  NEWS MEDICAL · 4 weeks
New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine... more
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