Using "Trojan horses" to combat cancer from within the tumor cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada, the Institute of Nanoscience of Aragon, the University of Zaragoza, and the Cancer Research UK Edinburgh Centre at the University of Edinburgh.... NEWS MEDICAL · 4 weeks
Scientists use catalysts to destroy cancerous cells from within  PHYS.ORG · 4 weeks
Using "Trojan horses" to combat cancer from within the tumour cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of... more
Encouraging normal liver cells to fight cancer  SCIENCE DAILY · 3 weeks
A study discovered that healthy liver tissue surrounding a tumor activates a defense mechanism that restrains tumor growth. Remarkably, the researchers found that hyperactivation of this mechanism above levels normally present in the liver,... more
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Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by... more
A new pathway to 'reprogram' killer cells  SCIENCE DAILY · 3 weeks
Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers have now discovered that the mechanism by which certain immune cells kill their target cells can also be used... more
Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor  NEWS MEDICAL · 4 weeks
Subpopulations of tumor cells may exhibit diverging behaviors from the bulk tumor due to an alternate stress response that diverts tumor cells from apoptotic death. more
[Editors' Choice] Myeloid cells: The Trojan horse for T cell invasion into the brain  Science Magazine · 2 weeks
C-type lectin receptors on myeloid cells regulate the activation and infiltration of T cells into the central nervous system in... more
Common antibiotic appears to boost the effect of radiation on tumor cells  NEWS MEDICAL · 5 days
The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after... more
What protects killer T cells from accidental death?  NEWS MEDICAL · 3 weeks
White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists from... more
Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy  Science Magazine · 2 weeks
In both human and murine systems, we have developed an adoptive cellular therapy platform against medulloblastoma and glioblastoma that uses dendritic cells pulsed with a tumor... more
IFN-{gamma}: The T cells license to kill stem cells in the inflamed intestine  Science Magazine · 1 week
IFN- produced by T cells directly induces intestinal stem cell death upon inflammation-induced intestinal injury (see the related Research Article by Takashima... more
New screening method identifies potential anticancer compounds that reawaken T cells  SCIENCE DAILY · 1 week
Scientists have developed a method for rapidly discovering potential cancer-treating compounds that work by resurrecting anti-tumor activity in immune cells called T cells. Cancerous tumors often... more
Metabolic adaptation ensures survival of colon cancer cells  SCIENCE DAILY · 2 days
Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the... more
Chemists' calculations may advance cancer prediction  SCIENCE DAILY · 2 days
A computational study by chemists showed the dynamics of tumor formation don't necessarily correlate with clinical data on lifetime cancer risks. It suggests biomarkers may someday be able to help predict when mutations in cells will... more
Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist  NEWS MEDICAL · 3 weeks
Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape. more
Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation  NEWS MEDICAL · 2 days
Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to... more
New model can help study the mechanisms of bone metastasis, tumor immune response  NEWS MEDICAL · 1 week
The Research Team reports the establishment of B6Ca P, an allograft tumor line from a Hi-Myc transgenic mouse that had been backcrossed... more
Researchers discover novel strategy to fight against liver cancer  NEWS MEDICAL · 3 weeks
A study conducted at the VIB-KU Leuven Center for Cancer Biology discovered that healthy liver tissue surrounding a tumor activates a defence mechanism that restrains tumor growth. more
Embryonal precursors of Wilms tumor  Science Magazine · 1 week
Adult cancers often arise from premalignant clonal expansions. Whether the same is true of childhood tumors has been unclear. To investigate whether Wilms tumor (nephroblastoma; a childhood kidney cancer) develops from a premalignant background, we examined the phylogenetic... more
New antimicrobial polymer can kill bacteria resistant to common antibiotics  NEWS MEDICAL · 2 days
Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, and Nanyang Technological University have designed an antimicrobial polymer that can kill bacteria resistant to... more
Researchers design polymer that can kill drug-resistant bacteria  PHYS.ORG · 2 days
Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, and Nanyang Technological University (NTU) have designed an antimicrobial polymer that can kill bacteria resistant to commonly used... more
UN says armed attacks in eastern Congo kill Ebola responders  ABC NEWS · 2 weeks
UN says attacks by armed groups in eastern Congo kill Ebola outbreak responders more
Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice  Science Magazine · 3 weeks
The Hippo signaling pathway and its two downstream effectors, the YAP and TAZ transcriptional coactivators, are drivers of... more
Researchers reprogram T cells to improve cancer immunotherapy  PHYS.ORG · 3 days
St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in... more
The Placenta 'Invades' the Uterus in the Same Way Cancer Invades the Body  LIVE SCIENCE · 2 weeks
The way human pregnancy works may make us more prone to malignant cancer than cows or horses. more
Dozens of potential new antibiotics discovered with free online app  PHYS.ORG · 4 weeks
A new web tool speeds the discovery of drugs to kill Gram-negative bacteria, which are responsible for the overwhelming majority of antibiotic-resistant infections and deaths. The tool also... more
Technique identifies T cells primed for certain allergies or infections  SCIENCE DAILY · 4 weeks
Researchers can now identify T cells reactive to a particular target from a patient's cells, and to perform high-throughput single-cell RNA sequencing of those cells. more
Transitional T cells could help improve cancer immunotherapy  NEWS MEDICAL · 1 week
In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted,... more
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