Researchers successfully performed targeted gene mutation in the zoonotic pathogen Chlamydia caviae.... SCIENCE DAILY · 2 weeks
Targeted gene modification in animal pathogenic chlamydia  PHYS.ORG · 2 weeks
Researchers at Umeå University (Sweden), in collaboration with researchers at the University of Maryland and Duke University (U.S.), now for the first time successfully performed targeted gene mutation in the zoonotic pathogen Chlamydia caviae. more
Researchers join forces to adapt novel genetic tool for zoonotic Chlamydia  NEWS MEDICAL · 2 weeks
The human pathogenic bacterium Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen worldwide. more
Study shows how Chlamydia bacteria enter human cells  NEWS MEDICAL · 3 weeks
Chlamydia are bacteria that can infect human and animal cells. Human health is particularly affected by Chlamydia pneumoniae (Cpn) and Chlamydia trachomatis. more
How Chlamydia gain access to human cells  SCIENCE DAILY · 3 weeks
Infection biologists have found out how the LIPP protein helps Chlamydia to infect human cells. These insights could provide the basis for prevention of chlamydial infections. more
Horizon Discovery announces divestment of animal models business to Envigo  NEWS MEDICAL · 1 week
Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announces an agreement to divest the Group’s animal research models... more
New gene therapy for epilepsy provides on-demand release of endogenous substance  SCIENCE DAILY · 3 weeks
Scientists have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site... more
Cooperative research center at LLNL aims to develop vaccines for chlamydia  NEWS MEDICAL · 4 weeks
A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory. more
Why targeted immuno-oncology drugs sometimes fail  SCIENCE DAILY · 4 weeks
Researchers report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies. more
How the SETD1A gene produces schizophrenia in mice  NEWS MEDICAL · 3 weeks
A new study published in the journal Neuron on October 9, 2019 reports that scientists have unlocked part of the secrets of the SETD1A gene – how mutations in the gene put... more
Discovery reveals why newer PD-1 targeted therapies sometimes fail  NEWS MEDICAL · 4 weeks
Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute report a discovery that helps scientists understand why some... more
Using CRISPR for dose-dependent activation of gene expressions  PHYS.ORG · 7 days
A team of researchers affiliated with several institutions in the U.S. has developed a way to use the CRISPR gene editing technique for dose-dependent activation of gene expressions. In their paper published... more
CRISPR: More than just for gene editing?  PHYS.ORG · 1 week
The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human gene pool," an ethically... more
For the first time: A method for measuring animal personality  SCIENCE DAILY · 1 week
A study on mice shows animal research may need to take into account the connection between genes, behavior and personality. more
Deleting a liver enzyme lowers the health risk of sweet treats (at least in mice)  SCIENCE DAILY · 4 weeks
Hepatic insulin resistance, caused by diets high in sugar and fat, can lead to type 2 diabetes. Researchers... more
Scientists invent animal-free testing of lethal neurotoxins  PHYS.ORG · 3 weeks
Animal testing will no longer be required to assess a group of deadly neurotoxins, thanks to University of Queensland-led research. more
Are humans changing animal genetic diversity worldwide?  PHYS.ORG · 4 weeks
Human population density and land use is causing changes in animal genetic diversity, according to researchers at McGill University. more
By cutting out one gene, researchers remove a tadpole's ability to regenerate  SCIENCE DAILY · 4 weeks
Tadpoles that can typically regrow amputated tails or limbs lost their ability to regenerate after researchers blocked the expression of a newly identified gene... more
Cell signalling breakthrough opens up new avenues for research  SCIENCE DAILY · 2 weeks
Researchers have shown that the phenomenon of protein modification (phosphorylation) in cell signalling is far more diverse and complex than previously thought. more
Adaptive mutability of colorectal cancers in response to targeted therapies  Science Magazine · 2 weeks
The emergence of drug resistance limits the efficacy of targeted therapies in human tumors. The prevalent view is that resistance is a fait accompli: when treatment is initiated,... more
Genetic mutation of APOE gene may provide protection against Alzheimer's disease  NEWS MEDICAL · 2 weeks
A team of researchers has identified that a genetic mutation of the APOE gene, the major susceptibility gene for late-onset Alzheimer's disease, may provide protection against... more
Gene therapy: Development of new DNA transporters  nanowerk · 24 hours
Scientists have developed new delivery vehicles for future gene therapies. They are using artificial fats to transport DNA into cells. more
By cutting out one gene, researchers remove a tadpole's ability to regenerate  PHYS.ORG · 4 weeks
Tadpoles of frogs that can typically regrow amputated tails or limbs lost their ability to regenerate after researchers blocked the expression of a newly... more
Genomic architecture and introgression shape a butterfly radiation  Science Magazine · 3 weeks
We used 20 de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate... more
GenBank can be trusted, study shows  SCIENCE DAILY · 4 weeks
Scientists working to identify coral reef organisms analyzed more than 4.7 million animal DNA sequences from GenBank, the most commonly used tool used to identify environmental DNA, and discovered that animal identification errors are surprisingly rare... more
The Link Between Animal Behavior and Neuroscience  NEWS MEDICAL · 7 days
News-Medical Life Sciences caught up with Zantiks at Neuroscience 2019 to have a chat about their animal behavior research solutions and their link to neuroscience. more
Gene deletion study identifies many new targets in malaria pathogen  PHYS.ORG · 5 days
Despite great efforts in medicine and science, more than 400,000 people worldwide are still dying of malaria. The infectious disease is transmitted by the bite of mosquitoes infected... more
How gene expression noise shapes cell fate  SCIENCE DAILY · 14 hours
Researcher develops a method for measuring gene expression noise across single cells in complex tissue. more
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