Toxoplasma gondii is best known as the parasite that may lurk in a cat's litter box. Nearly a third of the world's population is believed to live with a chronic Toxoplasma infection.... NEWS MEDICAL · 1 month
New technique may yield insights on the immune response to intestinal parasite infections  NEWS MEDICAL · 2 weeks
A new technique may help scientists study the body's immune response to intestinal parasite infections one gut cell at a time, according... more
[Research Articles] Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses  Science Magazine · 2 weeks
Solid tumors elicit a detectable immune response including the infiltration of tumor-associated macrophages (TAMs). Unfortunately, this... more
Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2  Science Magazine · 1 day
Malaria parasites suppress host immune responses to facilitate their survival, but the underlying mechanism remains elusive. Here, we found that blood-stage malaria... more
How the malaria virus evades the body’s immune response  NEWS MEDICAL · 1 week
Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. In 2018, there were over 200 million cases of... more
Targeting turncoat immune cells to treat cancer  SCIENCE DAILY · 1 week
A new study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. more
[Research Articles] Distinct immune phenotypes in infants developing asthma during childhood  Science Magazine · 3 weeks
Early exposure to environmental triggers may elicit trajectories to chronic inflammatory disease through deregulated immune responses. To address relations between early immune competence and development of... more
The pan-genome effector-triggered immunity landscape of a host-pathogen interaction  Science Magazine · 2 weeks
Effector-triggered immunity (ETI), induced by host immune receptors in response to microbial effectors, protects plants against virulent pathogens. However, a systematic study of ETI prevalence against species-wide pathogen diversity is... more
Tumor neoantigenicity assessment with CSiN score incorporates clonality and immunogenicity to predict immunotherapy outcomes  Science Magazine · 6 days
Lack of responsiveness to checkpoint inhibitors is a central problem in the modern era of cancer immunotherapy. Tumor neoantigens are... more
New technique allows scientists to study parasitic infections one cell at a time  SCIENCE DAILY · 2 weeks
A new technique may help scientists study the body's immune response to intestinal parasite infections one gut cell at a time. more
Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers  NEWS MEDICAL · 2 hours
A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide... more
Study may suggest new therapeutic approaches to control immune responses  NEWS MEDICAL · 3 weeks
Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response. more
New study shows how tumors disable the immune system to survive and spread  NEWS MEDICAL · 2 weeks
The goal of most cancers is to grow and take over the host's body. The immune system has long been in the... more
How the malaria parasite grows and multiplies  SCIENCE DAILY · 2 weeks
Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital clue in discovering how it has... more
Targeting regulatory T cells could boost the effects of cancer immunotherapy  NEWS MEDICAL · 1 week
A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh... more
Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice  NEWS MEDICAL · 4 weeks
An international research team which includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying... more
Grooves hold promise for sophisticated healing  PHYS.ORG · 3 weeks
Who ever said bioengineers can't get their groove on? The Rice University team led by Antonios Mikos says otherwise with its development of a groovy method to seed sophisticated, 3-D-printed tissue-engineering scaffolds with living cells to... more
Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics  Science Magazine · 6 days
Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the capacity to suppress adaptive immune responses during cancer. It remains elusive... more
Scientists create listeriosis-immune mice by turning off gene in myeloid cells  PHYS.ORG · 4 weeks
An international research team that includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying... more
Simple blood test measures the body's immune response to improve ovarian cancer diagnosis  NEWS MEDICAL · 1 week
Researchers have developed a simple blood test that measures the body's own immune response to improve diagnosis of ovarian cancer. more
New research shows how the malaria parasite grows and multiplies  PHYS.ORG · 2 weeks
Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital... more
Cheap nanoparticles stimulate immune response to cancer in the lab  PHYS.ORG · 4 weeks
University of Wisconsin-Madison researchers have developed nanoparticles that, in the lab, can activate immune responses to cancer cells. If they are shown to work as well in the... more
Cheap nanoparticles stimulate immune response to cancer in the lab  nanowerk · 4 weeks
Researchers have developed nanoparticles that, in the lab, can activate immune responses to cancer cells. If they are shown to work as well in the body as they... more
Individual response to Ebola predicted by new method  NEWS MEDICAL · 2 weeks
The Ebola virus produces widely varying reactions, from asymptomatic illness to death, in people depending on the individual's susceptibility. But what drives this difference in response? A new study published in the... more
New combination treatment could help fight advanced melanoma  NEWS MEDICAL · 4 weeks
A study by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that using an immunotherapy drug called NKTR-214, also known as bempegaldesleukin, in combination with an infusion of anti-tumor immune cells,... more
Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells  PHYS.ORG · 1 day
Patients with autoimmune diseases like multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis have an imbalance between two types of immune system T cells.... more
A host's genes likely influence the spread of antibiotic resistance  SCIENCE DAILY · 4 weeks
New findings in mSphere suggest that the genetic makeup of the host organism can influence the transfer of plasmids. By identifying the host factors that facilitate or stop... more
Major breakthrough in understanding how malaria parasite grows and multiplies  NEWS MEDICAL · 2 weeks
Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital... more
Sophisticated Soviet spy radio discovered buried in former forest in Germany  LIVE SCIENCE · 1 week
Archaeologists have found a sophisticated Soviet spy radio that was buried in a former forest in Germany shortly before the fall of the Iron Curtain. more
New target protein linked to regulation, movement of tumor-associated macrophages  NEWS MEDICAL · 4 weeks
Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells... more
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