A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality.... PHYS.ORG · 1 month
Insulin signaling suppressed by decoys  SCIENCE DAILY · 1 day
The discovery of an insulin 'decoy' molecule shakes up understanding of insulin signaling, with implications for diabetes, longevity and aging research. more
New tool probes gene regulation  PHYS.ORG · 3 weeks
DNA methylation (DNAme) is a modification of the genome—an epigenetic "mark"—that is required for proper cellular differentiation. It has been implicated in the regulation of gene expression, but its role in this stepwise process is poorly understood. more
Random pulsing of gene expression contributes to pattern formation during development  NEWS MEDICAL · 7 days
A team of Cambridge scientists working on the intersection between biology and computation has found that random gene activity helps patterns form during development of a... more
Engineered symbionts activate honey bee immunity and limit pathogens  Science Magazine · 4 weeks
Honey bees are essential pollinators threatened by colony losses linked to the spread of parasites and pathogens. Here, we report a new approach for manipulating bee gene expression and protecting... more
One in five operations with in-network surgeons and facilities could result in surprise bills  NEWS MEDICAL · 2 weeks
As if recovering from surgery wasn't hard enough, a new study shows that one in five operations could result in... more
When your doctor is also a lobbyist: Inside the war over surprise medical bills  NEWS MEDICAL · 2 weeks
When Carol Pak-Teng, an emergency room doctor in New Jersey, hosted a fundraiser in December for Democratic freshman Rep. Tom... more
Solving the riddle of strigolactone biosynthesis in plants  SCIENCE DAILY · 4 weeks
Researchers have discovered the orobanchol synthase responsible for converting the strigolactone (SL) carlactonoic acid, which promotes symbiotic relationships with fungi, into the SL orobanchol, which causes root parasitic weeds to germinate. By... more
A fundamental discovery about how gene activity is regulated  PHYS.ORG · 3 weeks
Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a fundamental mechanism that regulates gene activity in cells. The newly discovered mechanism targets RNA, or ribonucleic acid, a... more
Engineering light-controllable CAR T cells for cancer immunotherapy  Science Magazine · 7 days
T cells engineered to express chimeric antigen receptors (CARs) can recognize and engage with target cancer cells with redirected specificity for cancer immunotherapy. However, there is a lack of ideal CARs for... more
Scientists explore how females shut off their second X chromosome  PHYS.ORG · 3 weeks
Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Institut Curie in Paris have shown that the protein SPEN plays a crucial role in the process... more
How too much fluoride causes defects in tooth enamel  SCIENCE DAILY · 7 days
Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel -- a novel explanation for how dental fluorosis, a condition caused... more
Research provides new insights into molecular basis of X-chromosome inactivation  NEWS MEDICAL · 3 weeks
Researchers at the European Molecular Biology Laboratory in Heidelberg and Institut Curie in Paris have shown that the protein SPEN plays a crucial role in the process of... more
Accumulated brain protein affects genes in Alzheimer's disease  NEWS MEDICAL · 2 weeks
A new study published in February 2020 in the journal Cell Reports shows how the build-up of specific brain cell proteins are linked to altered gene expression that causes the symptoms of... more
Study reveals how overexposure to fluoride causes defects in tooth enamel  NEWS MEDICAL · 1 week
Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel- a novel explanation for how dental fluorosis,... more
Researchers discover new mechanism involved in the expression of Down syndrome  NEWS MEDICAL · 5 days
Researchers at CHU Sainte-Justine and Université de Montréal have discovered a new mechanism involved in the expression of Down syndrome, one of the main causes of... more
Marine bacteria genes can help track environmental changes caused by humans  NEWS MEDICAL · 2 weeks
The gene expression of marine bacteria can be a valuable sensor for discovering environmental changes caused by humans. Furthermore, bacteria help to clean our oceans and... more
Bacteria genes help researchers keep track of human environmental impact in oceans  PHYS.ORG · 2 weeks
The gene expression of marine bacteria can be a valuable sensor for discovering environmental changes caused by humans. Furthermore, bacteria help to clean our... more
Scientists create virus-resistant tomato plants  PHYS.ORG · 4 hours
Researchers of Valencia's Polytechnic University (UPV) and the Spanish National Research Council (CSIC) have used tools that regulate gene expression in order to produce tomato plants that are resistant to the spotted wilt virus (TSWV), thus proving the... more
Researchers discover a genetic mechanism that affects birth defects, some cancers  PHYS.ORG · 4 weeks
Scientists have understood for some time that proper embryonic development depends in large part on transcriptional repressors, proteins that prevent genes from being expressed at inappropriate... more
New understanding of neurovascular coupling  NEWS MEDICAL · 7 days
A new study published in the journal Nature in February 2020 reports the discovery of a control mechanism in mouse brains, which makes it possible to sensitively regulate the flow of blood to different areas of the brain,... more
Study reveals similarities between bee brains and human brains  PHYS.ORG · 5 hours
In a discovery that could open new avenues for understanding of the brain, researchers have found similarities between the brain activity of honey bees and humans. more
Intrinsic disorder controls two functionally distinct dimers of the master transcription factor PU.1  Science Magazine · 5 days
Transcription factors comprise a major reservoir of conformational disorder in the eukaryotic proteome. The hematopoietic master regulator PU.1 presents a well-defined model... more
Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458  Science Magazine · 3 weeks
During endoderm formation, cell identity and tissue morphogenesis are tightly controlled by cell-intrinsic and cell-extrinsic factors such as biochemical and... more
Tiny prehistoric lizard sheds light on reptile evolution  PHYS.ORG · 6 days
The discovery of a new species of prehistoric reptile from Germany is reported this week in Scientific Reports. The anatomical features of the species, named Vellbergia bartholomaei, add to our understanding of... more
Increased risk of uterine cancer linked to 24 gene variants  NEWS MEDICAL · 1 week
The risk of uterine endometrial cancer is increased by 24 gene variants that code for different cellular processes such as cell growth and death, gene regulation, and estrogen... more
Insulin signaling suppressed by decoys  PHYS.ORG · 1 day
In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. Their study, involving the roundworm C. elegans, reveals that a "decoy" receptor... more
Researchers locate specific mutation in the gene responsible for Chédiak-Higashi syndrome  NEWS MEDICAL · 4 weeks
Humans and animals are made up of trillions of cells, and each cell contains DNA specific to that individual. Therefore, identifying DNA that causes genetic disorders... more
Scientists discover new biological mechanism of insulin signaling  NEWS MEDICAL · 16 hours
In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. more
MORE SCIENCE VIDEO
Discovery of entirely new class of RNA caps in bacteria
PHYS.ORG
Generativity: Young activists are motivated by concern for future generations
PHYS.ORG
Aerosol optical tweezers advance understanding of airborne particles
PHYS.ORG
First genetic evidence of resistance in some bats to white-nose syndrome, a devastating fungal disease
PHYS.ORG
How genetic testing is helping scientists save animals from disease and illegal hunting
PHYS.ORG
Creating custom light using 2-D materials
PHYS.ORG
New all-sky search reveals potential neutrino sources
PHYS.ORG
Painting of deity found inside 3,000-year-old coffin
PHYS.ORG
Physically producing computer-generated artificial genomes to understand DNA
PHYS.ORG
Study uncovers new electronic state of matter
PHYS.ORG
Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease
NEWS MEDICAL
When your doctor is also a lobbyist: Inside the war over surprise medical bills
NEWS MEDICAL
Web tool offers instant access to global climate data
PHYS.ORG
A less-contentious alternative to biodiversity offsetting
PHYS.ORG
Astroscale wins first half of JAXA debris-removal mission 
SPACE NEWS
FRESH SCIENCE