In a new study published in Nature Communications, researchers at Karolinska Institutet show that MAIT cells (mucosa-associated invariant T cells), part of the human immune system, respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection.... NEWS MEDICAL · 5 days
A New Discovery about MAIT Cells Sheds Light on Early-Phase HIV Infection  NEWS MEDICAL · 5 days
Researchers at the Karolinska Institutet, Sweden, have made an important discovery about a poorly understood group of immune cells (mucosa-associated invariant T [MAIT]cells) that... more
New Yorkers are being treated sooner after HIV infection, study shows  NEWS MEDICAL · 2 weeks
The most effective way to reduce HIV-related deaths and prevent onward transmission is to diagnose and treat all persons as soon as possible after HIV infection.... more
Intervention for hospitalized HIV patients reduces infection rates and increases engagement in care  NEWS MEDICAL · 2 weeks
Providing multidisciplinary team consults for HIV patients while they are hospitalized to help address social and medical barriers reduces future infection rates... more
Smoking dormant HIV virus out into the open to develop a cure  NEWS MEDICAL · 1 week
Ever since antiretroviral treatments against HIV infection were introduced in 1996, scientists have eagerly been hunting for a cure for the disease. more
Intervention for patients hospitalized with HIV improved reengagement and outcomes of care  SCIENCE DAILY · 1 week
Providing multidisciplinary team consults for HIV patients while they are hospitalized to help address social and medical barriers reduces future infection rates and boosts... more
New HIV infections among gay and bisexual men in the UK fall by 71 percent  NEWS MEDICAL · 2 days
The Human Immunodeficiency Virus (HIV) is a highly contagious infection usually transmitted through body fluids during sexual contact,... more
Timing is key: preventing infant SHIV infection by PEP  NEWS MEDICAL · 1 week
Researchers tested methods to prevent development of SHIV, an infection similar to HIV, in infant macaque monkeys. more
Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion  Science Magazine · 4 days
Microglia and infiltrating macrophages are thought to orchestrate the central nervous system (CNS) response to injury; however, the similarities between these cells make it... more
How the rice blast fungus 'eats' its own cell wall to launch an attack  PHYS.ORG · 2 weeks
All living organisms respond and adapt to changes in their environment. These responses are sometimes so significant that they cause... more
Single dose of antibodies can knock out HIV in newborns  SCIENCE DAILY · 1 week
A single dose of an antibody-based treatment can prevent HIV transmission from mother to baby, new nonhuman primate research suggests for the first time. This is the first... more
ART may not be completely effective in restoring immune protection, study suggests  NEWS MEDICAL · 2 weeks
A study led by researchers from SUNY Downstate Health Sciences University and Oregon Health & Science University, published in the Journal of Infectious Diseases,... more
B-cell enrichment predictive of immunotherapy response in melanoma, sarcoma and kidney cancer  SCIENCE DAILY · 4 days
Multiple studies out indicate that a patient's response to immune checkpoint blockade may depend on B cells located in special structures within the tumor. more
Radical procedures to treat oral infections are not necessary before stem cell transplantation  NEWS MEDICAL · 2 weeks
A recently published study indicates that oral infections seem to have no association with the risk of stem cell transplantation patients dying... more
Study provides insights into how viral infection can continue to affect immunity  NEWS MEDICAL · 5 days
The strength of the immune system in response to respiratory infections is constantly changing, depending on the history of previous, unrelated infections, according to... more
[Research Articles] Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy  Science Magazine · 2 weeks
The exocrine pancreas expresses the highest concentrations of fibroblast growth factor 21 (FGF21) in the body, where it maintains acinar cell proteostasis.... more
Scientists develop way to track salmonella infection in real time  PHYS.ORG · 2 weeks
When bacteria like salmonella infect and sicken people, they hijack a person's cell proteins to develop a defense against an immune response. Understanding how that works and developing... more
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance  Science Magazine · 3 days
Negative checkpoint regulators (NCRs) temper the T cell immune response to self-antigens and limit the development of autoimmunity. Unlike all other NCRs... more
Taking one for the team: How bacteria self-destruct to fight viral infections  PHYS.ORG · 1 week
Researchers at University of California San Diego School of Medicine have discovered how a new immune system works to protect bacteria from bacteriophages (phages),... more
Pregnant women with HIV do not always receive recommended antiretroviral medications  NEWS MEDICAL · 4 weeks
Pregnant women living with HIV don't always receive antiretroviral medications recommended for use in pregnancy, according to a recent study published in Jama Network Open this... more
B cell count tells how certain cancers will respond to immunotherapy  NEWS MEDICAL · 3 days
Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the... more
Scaling up use of opioid agonist therapies could help combat Ukraine’s HIV epidemic  NEWS MEDICAL · 2 weeks
A new study led by Yale University researchers finds that scaling up use of methadone and buprenorphine -- medications for treating opioid... more
Study uncovers how rice blast fungus uses its own cell wall to launch an attack  NEWS MEDICAL · 5 days
In response to environmental changes and nutrient starvation, cells are known to undergo extreme alterations. This includes switching... more
Effort to control opioids in an ER leaves some sickle cell patients in pain  NEWS MEDICAL · 2 weeks
India Hardy has lived with pain since she was a toddler — ranging from dull persistent aches to acute flare-ups... more
Harmful genetic mutations in healthy donors' stem cells may create problems in AML patients  NEWS MEDICAL · 3 days
A stem cell transplant - also called a bone marrow transplant - is a common treatment for blood cancers, such... more
HIV 'hotspots' do not necessarily fuel the epidemic  NEWS MEDICAL · 4 days
Areas of high HIV prevalence, known as 'hotspots', do not necessarily fuel the epidemic in the wider population, say researchers. more
One dose of HPV vaccine may prevent infection from cancer-causing virus, study reveals  NEWS MEDICAL · 3 weeks
A new study revealed that one dose of the HPV vaccine may prevent infection from the potential cancer-causing virus, according to research... more
Single dose of antibody-based treatment can beat HIV in newborn babies  NEWS MEDICAL · 2 weeks
A single dose of an antibody-based treatment can prevent HIV transmission from mother to baby, new nonhuman primate research suggests for the first time. The findings... more
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