A team headed by ICREA researchers Salvador Aznar Benitah and Fran Supek concludes that care should be taken with drugs that inhibit epigenetic factors.... NEWS MEDICAL · 3 months
New approach identifies epigenetic changes in leukemia cells for patients undergoing ibrutinib treatment  NEWS MEDICAL · 4 weeks
Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy... more
Finding second hits to knock out leukemia  SCIENCE DAILY · 4 weeks
Targeted drugs are a cornerstone of personalized medicine, yet come with important drawbacks. They restrain disease progression -- but rarely eradicate the cancer. Patients therefore need to take the drugs essentially forever, exposing them... more
Novel autism mouse model based on an epigenetic gene developed  SCIENCE DAILY · 3 weeks
In a new study, researchers describe how, in a novel mouse model, epigenetic regulation negatively impacts a downstream gene specifically involved in neurodevelopment and associated behaviors. more
New welfare tool to help improve the lives of elephants in human care  SCIENCE DAILY · 2 weeks
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New welfare tool to help improve the lives of elephants in human care  PHYS.ORG · 2 weeks
Zoos and safari parks in the UK are using a special new tool to help them more successfully monitor the wellbeing of... more
New eHealth tool shows potential to improve quality of asthma care  NEWS MEDICAL · 1 week
A new electronic decision support tool for managing asthma has the potential to improve the quality of asthma care in primary care settings, suggests a study... more
Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer's  NEWS MEDICAL · 3 days
Researchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of... more
Electronic tool has potential to improve asthma care  SCIENCE DAILY · 1 week
A new electronic decision support tool for managing asthma has the potential to improve the quality of asthma care in primary care settings, suggests a new study. more
Study shows why America needs more primary care doctors  NEWS MEDICAL · 4 weeks
The United States health care system is generally centered around hospitals and specialty care. The value of primary care, however, has remained unclear and debated, in part due to limited... more
Study shows how neuroactive steroids inhibit activity of pro-inflammatory proteins  NEWS MEDICAL · 1 week
For the first time, scientists discovered how neuroactive steroids naturally found in the brain and bloodstream inhibit the activity of a specific kind of protein called Toll-like receptors,... more
Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs  NEWS MEDICAL · 4 hours
Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide. They are... more
Future changes in human well-being to depend more on social factors than economic factors  PHYS.ORG · 4 weeks
The changes in the perception of personal well-being that could take place in the next three decades, on a global... more
Researchers conduct extensive comparison of drugs used in treating neuroendocrine tumors  NEWS MEDICAL · 1 week
An increasing number of new anti-cancer drugs are made available each year. During the authorization process, such new drugs usually undergo comparisons to one, but only... more
Study finds early home and family factors linked to development of obesity  NEWS MEDICAL · 2 weeks
A new 21-year longitudinal study identified multiple risk factors related to the family and home environment associated with the timing and faster increase in... more
NIH researchers discover that anti-flu antibodies can inhibit two different viral proteins  NEWS MEDICAL · 4 weeks
Researchers from the National Institutes of Health have discovered that antibodies that may form the basis of a universal flu vaccine inhibit a second... more
Study: Freestanding emergency departments charge more than urgent care centers  NEWS MEDICAL · 4 weeks
Freestanding emergency departments may charge more than urgent care centers (UCCs) to provide care for fewer patients who have similar characteristics and conditions, according to a study released... more
New study estimates prevalence and risk factors for misuse of prescribed opioids  NEWS MEDICAL · 2 weeks
A new Pharmacoepidemiology & Drug Safety study estimates the prevalence and risk factors for self-reported misuse of prescribed opioids in the general adult population. more
More primary care physicians leads to longer life spans  SCIENCE DAILY · 5 days
New research shows us just how important primary care physicians are in prolonging our lives. Every 10 additional primary care physicians per 100,000 people in the United States was associated... more
Study reveals how glioblastomas resist the effects of antiangiogenic drugs  NEWS MEDICAL · 3 weeks
A study led by investigators from Massachusetts General Hospital (MGH) and the University of Cyprus reveals details of a way the dangerous brain tumors called glioblastomas resist the... more
Complex interplay of two growth factors key to fast-acting antidepressant actions  NEWS MEDICAL · 3 weeks
A study by researchers at Yale University reveals a complex interplay of two different growth factors in the rapid and long-lasting antidepressant effects of ketamine. more
Cannabinoid compounds may inhibit growth of colon cancer cells  SCIENCE DAILY · 2 weeks
Medical marijuana has gained attention in recent years for its potential to relieve pain and short-term anxiety and depression. Now, researchers say some cannabinoid compounds may actually inhibit the growth... more
Future changes in human well-being to depend more on social factors than economic factors  SCIENCE DAILY · 4 weeks
The changes in the perception of personal well-being that could take place in the next three decades, on a global... more
'More unites us than divides us' say researchers  PHYS.ORG · 4 weeks
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Hens that lay human proteins in eggs offer cost-effective method of producing new drugs  NEWS MEDICAL · 4 weeks
Chickens that are genetically modified to produce human proteins in their eggs can offer a cost-effective method of producing certain... more
Study examines link between supply of primary care physicians and life expectancy  NEWS MEDICAL · 5 days
This study used U.S. population data to identify changes in the supply of primary care physicians across counties from 2005 to 2015 and the... more
Hens that lay human proteins in eggs offer future therapy hope  SCIENCE DAILY · 4 weeks
Chickens that are genetically modified to produce human proteins in their eggs can offer a cost-effective method of producing certain types of drugs, research suggests. Researchers... more
Study may explain why once-promising cancer drugs failed  SCIENCE DAILY · 4 weeks
Nearly two decades ago, a class of once-promising cancer drugs called MMP inhibitors mysteriously failed in clinical trials. Now scientists think they may have an explanation. A new study shows that when... more
Few primary care physicians lack enough knowledge of cancer treatment options  NEWS MEDICAL · 1 week
The idea of team-based cancer care most often focuses on involving primary care physicians in the care of cancer survivors. But research has shown patients are... more
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