A sophisticated chip the size of a coin in which cartilage can be cultivated and which can later be subjected to mechanical stress such that it generates the effects of Osteoarthrosis.... NEWS MEDICAL · 3 weeks
Retina-on-a-chip provides powerful tool for studying eye disease  nanowerk · 3 weeks
This cutting-edge tool may provide a useful alternative to existing models for studying eye disease and allow scientists to test the effects of drugs on the retina more efficiently. more
Lab-on-a-chip drives search for new drugs to prevent blood clots  PHYS.ORG · 4 weeks
A tiny lab the size of a postage stamp could be the next big thing in the search for safer anti-clotting drugs to prevent heart attacks and strokes. more
New gold-based molecules more effective at killing cancer cells with fewer toxic side effects  NEWS MEDICAL · 2 weeks
Researchers have engineered gold-based molecules that target cancer cells and leave healthy cells unharmed, in a critical step towards precision... more
Lab-on-a-chip drives search for new drugs to prevent blood clots  SCIENCE DAILY · 4 weeks
The effectiveness of current anti-clotting medication can be limited due to the risk of complications. This is driving a need for alternatives that can both prevent the formation... more
Simple computational models can help predict post-traumatic osteoarthritis  SCIENCE DAILY · 4 weeks
Researchers have developed a method to predict post-traumatic osteoarthritis in patients with ligament ruptures using a simplified computational model. The researchers also verified the model predictions against measured structural and compositional changes... more
Study reveals link between popular pain medication and greater risk of hypoglycemia  NEWS MEDICAL · 3 weeks
Since its approval in 1995, the opioid tramadol (marketed as ConZip and Ultram) has become a widely prescribed remedy for osteoarthritis and other painful... more
Predicting post-traumatic osteoarthritis using simplified computational models  NEWS MEDICAL · 4 weeks
Knee joint injuries, such as ligament rupture, are common in athletes. As the intact joint ligaments offer a precondition for joint stability, ligament injuries are often surgically reconstructed. However, in many cases these injuries... more
Researchers develop new cocktail of drugs that shrink pancreatic tumors  NEWS MEDICAL · 1 week
Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save... more
Pancreas on a chip: Organ-on-a-chip and stem-cell tech combined  SCIENCE DAILY · 3 weeks
'Islet-on-a-chip' offers continuous monitoring of insulin-producing cells, indicating whether they have therapeutic value and are suitable for transplant. Miniature, automated, easy-to-use device improves decision making for clinicians. New method streamlines... more
Retina-on-a-chip provides powerful tool for studying eye disease  SCIENCE DAILY · 3 weeks
The development of a retina-on-a-chip, which combines living human cells with an artificial tissue-like system, has been described. more
Drug tolerant Tuberculosis could soon be tracked using genes  NEWS MEDICAL · 1 week
A team of researchers from the Rutgers New Jersey Medical School have found genetic foot prints of tuberculosis bacteria that are resistant to the commonly used anti-tubercular drugs. This could... more
Developing a richer understanding of natural sciences critical to making better policy decisions  PHYS.ORG · 2 weeks
To fully understand the challenges of progressive environmental transformation requires that policy makers develop a more sophisticated and nuanced relationship with the... more
Retina-on-a-chip may provide useful alternative to existing models for studying eye disease  NEWS MEDICAL · 3 weeks
The development of a retina-on-a-chip, which combines living human cells with an artificial tissue-like system, has been described today in the open-access journal eLife. more
New lab-on-a-chip could help development of novel anti-clotting therapies  NEWS MEDICAL · 4 weeks
A tiny lab the size of a postage stamp could be the next big thing in the search for safer anti-clotting drugs to prevent heart attacks and strokes. more
[Research Articles] Topographic modeling of early human osteoarthritis in sheep  Science Magazine · 2 weeks
Articular cartilage damage occurring during early osteoarthritis (OA) is a key event marking the development of the disease. Here, we modeled early human OA by gathering detailed spatiotemporal... more
More targeted, less toxic: The golden future of cancer treatment  SCIENCE DAILY · 2 weeks
New synthetic molecules are up to 24 times more effective at killing cancer cells than a widely-used cancer drug and they're built with resistance-fighting features to keep them... more
Organ-on-e-chip: Three-dimensional self-rolled biosensor array for electrical interrogations of human electrogenic spheroids  Science Magazine · 4 weeks
Cell-cell communication plays a pivotal role in coordination and function of biological systems. Three-dimensional (3D) spheroids provide venues to explore cellular communication for tissue... more
Lab-on-a-chip may help identify new treatments for liver disease  SCIENCE DAILY · 3 weeks
Investigators have developed a 'lab on a chip' technology that can simulate different levels of Non-alcoholic Fatty Liver Disease progression. more
Pancreas on a chip: Scientists combine organ-on-a-chip and stem-cell technologies  PHYS.ORG · 3 weeks
By combining two powerful technologies, scientists are taking diabetes research to a whole new level. In a study led by Harvard University's Kevin Kit Parker, microfluidics and human,... more
Remora-inspired suction disk mimics fish's adhesion ability, offers evolutionary insight  SCIENCE DAILY · 2 weeks
Researchers offer new insight into the evolution of the suction ability of remora fishes, showcasing a bioinspired suction disk that mimics, and can exceed, the fish's uncanny powers... more
Scientists find psychiatric drugs affect gut contents  SCIENCE DAILY · 1 week
Scientists have found that antidepressants and other psychiatric drugs can change the quantity and composition of gut bacteria in rats. These results raise questions about the specificity of psychoactive drug action, and if confirmed... more
Nanotherapy: Controlled delivery of chemotherapeutics to fight cancer stem cells  PHYS.ORG · 1 week
Chemotherapy is one of the most used treatments against cancer, along with surgery and radiotherapy. In a chemotherapy treatment, one or several drugs are administered to the patient... more
Islet-on-a-Chip to study the fundamental biology of diabetes  NEWS MEDICAL · 3 weeks
By combining two powerful technologies, scientists are taking diabetes research to a whole new level. In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have... more
Researchers develop more efficient method to produce building blocks needed for drugs  NEWS MEDICAL · 5 days
Researchers at Tokyo University of Agriculture and Technology in Japan and Mount Allison University in Canada have developed a more efficient method to produce... more
Optical vacuum cleaner can manipulate nanoparticles  PHYS.ORG · 1 week
Scientists at Tomsk Polytechnic University jointly with Russian and international colleagues developed the concept for constructing an "optical vacuum cleaner." Due to its optical properties, it can trap nanoparticles from the environment. Currently, there are no... more
High-tech gel aids delivery of drugs  PHYS.ORG · 3 weeks
Drugs that help prevent the formation of unwanted or harmful proteins are currently being developed to treat a number of diseases, including cancer. The drugs are based on small interfering RNA, or siRNA, which are pieces... more
Targeting cell division in pancreatic cancer  SCIENCE DAILY · 4 weeks
Study provides new evidence of synergistic effects of drugs that inhibit cell division and support for further clinical trials. more
Polypill holds promise for tackling cardiovascular disease  SCIENCE DAILY · 2 weeks
A team of researchers evaluated whether it would be cost-effective to combine several medications into a single 'cardiovascular polypill' for patients who have had a previous heart attack or stroke, instead of prescribing the... more
Researchers explore remodeling of cardiac tissues post-aortic valve replacement  NEWS MEDICAL · 5 days
University of Colorado Boulder engineers and faculty from the Consortium for Fibrosis Research & Translation at the University of Colorado Anschutz Medical Campus have teamed up to develop biomaterial-based "mimics"... more
High-tech gel aids delivery of drugs  SCIENCE DAILY · 3 weeks
Drugs that help prevent the formation of unwanted or harmful proteins are currently being developed to treat a number of diseases, including cancer. The drugs are based on small interfering RNA, or siRNA, which are pieces... more
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