While it has long been recognized that mutated gene NPM1 plays an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.... NEWS MEDICAL · 3 months
New drug compounds show promise in treating acute myeloid leukemia  NEWS MEDICAL · 4 weeks
Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one... more
Study discovers new therapy for aggressive blood cancer  NEWS MEDICAL · 1 week
Acute myeloid leukemia is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells. more
New therapy for aggressive blood cancer discovered  SCIENCE DAILY · 1 week
Acute myeloid leukemia (AML) is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells. Only twenty-five percent of... more
Drug compound could be next-generation treatment for aggressive form of leukemia  SCIENCE DAILY · 4 weeks
Researchers are developing a series of drug compounds that have shown promise in treating acute myeloid leukemia, an aggressive blood cancer that is one of the... more
Novel therapeutic approach for treatment of leukemia  NEWS MEDICAL · 4 weeks
The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia. more
Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children  SCIENCE DAILY · 1 week
Progress reported on understanding why Hispanic children are more likely to develop acute lymphoblastic leukemia and to die of the... more
Study: Prolonged presence of precursor cells in thymus may give rise to leukemia  NEWS MEDICAL · 4 weeks
Acute T-cell lymphoblastic leukemia is a rare type of blood cancer that affects mostly children. This blood cancer appears from the precursor... more
It's all in the code: Protein production efficiency can be predicted by gene sequence  SCIENCE DAILY · 3 weeks
Scientists explored mRNA and protein public databases to unravel hidden meanings of the genetic code. Using a metric derived from... more
Molecular Velcro helps illuminate DNA repair  PHYS.ORG · 2 weeks
Using a piece of molecular "Velcro" to attach a light-emitting probe to a protein molecule, University of Wollongong (UOW) researchers have unlocked the mystery of how an important protein goes about repairing damaged DNA in bacteria,... more
Alzheimer's: How do tau tangles grow?  MNT · 2 weeks
Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length. more
Medical News Today: Alzheimer's: How do tau tangles grow?  MNT · 2 weeks
Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length. more
PET/CT imaging agent shows promise for better diagnosis of acute venous thromboembolism  SCIENCE DAILY · 7 days
Researchers report that a new nuclear medicine tracer may allow better diagnosis of acute venous thromboembolism (VTE). Acute VTE is a disease that includes... more
Myeloid cells in the central nervous system: So similar, yet so different  Science Magazine · 2 weeks
Dissection of the heterogeneity of CNS myeloid cells reveals functionally distinct subsets that govern encephalitogenic T cells. more
Cells in the intestines play key role in inducing acute inflammatory episodes  NEWS MEDICAL · 4 weeks
Medical researchers discover a type of cell which induces acute inflammatory episodes in bowel diseases. more
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation  Science Magazine · 4 weeks
The innate immune cell compartment is highly diverse in the healthy central nervous system (CNS), including parenchymal and non-parenchymal macrophages. However, this complexity is increased in... more
How rapeseed could be used as a protein source for human nutrition  SCIENCE DAILY · 3 weeks
Rapeseed doesn't just contain oil but high-quality protein, too. However, protein extracts from rapeseed have an intense, bitter off-taste. Researchers have now identified the... more
Protein production efficiency can be predicted by gene sequence  PHYS.ORG · 3 weeks
Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact quantities... more
Medical News Today: What to know about acute respiratory failure  MNT · 12 hours
Symptoms of acute respiratory failure include shortness of breath and confusion. Causes include lung-related conditions and chest trauma. Learn more about acute respiratory failure here. more
Predicting sequence from structure  MIT · 1 week
Researchers have devised a faster, more efficient way to design custom peptides and perturb protein-protein interactions. more
New approach identifies epigenetic changes in leukemia cells for patients undergoing ibrutinib treatment  NEWS MEDICAL · 4 weeks
Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy... more
Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children  NEWS MEDICAL · 1 week
St. Jude Children's Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased... more
Researchers uncover mechanism of protein transport in mitochondria  PHYS.ORG · 2 weeks
The research labs of Dr. Thomas Becker and Dr. Nikolaus Pfanner from the Institute for Biochemistry and Molecular Biology at the University of Freiburg have reported a function of the metabolite channel... more
Opposite effect: Protein widely known to fight tumors also boosts cancer growth  SCIENCE DAILY · 3 weeks
Researchers studying p53, the heralded cancer-fighting 'guardian of the genome,' found that the human protein also plays a role in promoting tumors, in addition... more
Leukemia promotes premature aging in the bone marrow  NEWS MEDICAL · 3 weeks
Leukemia promotes premature aging in healthy bone marrow cells - according to new research from the University of East Anglia. more
Researchers link protein clusterin to many facets of cardiometabolic syndrome risk  NEWS MEDICAL · 3 weeks
During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have... more
New study uncovers key protein in the production of insulin  NEWS MEDICAL · 4 weeks
The crucial hormone insulin needs help acquiring the right structure. A protein that assists in the process of insulin folding has just been discovered in a new study... more
New acute porphyria treatment shows promising results in clinical study  NEWS MEDICAL · 2 weeks
Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only... more
Over 1 in 3 adults miss the mark on protein, finds study  NEWS MEDICAL · 2 days
Walk into any grocery store and you'll find high-protein products dominating shelf space throughout the aisles. The benefits of protein are well established, and... more
Medical News Today: These immune cells renew themselves after acute kidney injury  MNT · 4 weeks
A new study in mice finds that after acute kidney injury, kidney-resident macrophages reprogram to a state that is similar to those in newborn... more
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