A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.... NEWS MEDICAL · 4 days
Gene-editing tool CRISPR repurposed to develop better antibiotics  SCIENCE DAILY · 4 days
Scientists have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones. more
Gene-editing tool CRISPR repurposed to develop better antibiotics  PHYS.ORG · 4 days
A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues... more
Researchers overcome hurdle in CRISPR gene editing for muscular dystrophy  SCIENCE DAILY · 1 week
The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic... more
Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy  NEWS MEDICAL · 7 days
The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be... more
Researchers develop CRISPR-based method to control pests with precision-guided genetics  NEWS MEDICAL · 1 week
Using the CRISPR gene editing tool, Nikolay Kandul, Omar Akbari and their colleagues at UC San Diego and UC Berkeley devised a method of altering key genes that... more
Giving Cas9 an 'on' switch for better control of CRISPR gene editing  PHYS.ORG · 5 days
CRISPR-Cas9 is a revolutionary tool in part because of its versatility: created by bacteria to chew up viruses, it works equally well in human... more
Gene-editing tool CRISPR/Cas9 shown to limit impact of certain parasitic diseases  SCIENCE DAILY · 38 minutes
Researchers have successfully used CRISPR/Cas9 to limit the impact of schistosomiasis and liver fluke infection, which affects more than a quarter of a billion people in... more
CRISPR study reveals new immune system regulators  SCIENCE DAILY · 5 days
Scientists have created the first retroviral CRISPR-Cas9 gene editing library to explore the regulation of mouse T cells, which are key cells in the immune system. Researchers mapped the most important genes for controlling... more
New CRISPR-based technology developed to control pests with precision-guided genetics  PHYS.ORG · 1 week
Using the CRISPR gene editing tool, Nikolay Kandul, Omar Akbari and their colleagues at UC San Diego and UC Berkeley devised a method of altering key genes that... more
Leveraging the power of CRISPR-Cas9 to awaken antibiotics from their silent gene clusters  PHYS.ORG · 4 weeks
The bacterium Streptomyces roseosporus is the source of many common antibiotics such as daptomycin, which is active against methicillin-resistant Staphylococcus aureus (MRSA)... more
CRISPR may restore effectiveness of chemotherapies used to treat lung cancer  NEWS MEDICAL · 4 weeks
The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a... more
New CRISPR-based technology developed to control pests with precision-guided genetics  SCIENCE DAILY · 1 week
Using the CRISPR gene editing tool, researchers have developed a new way to control and suppress populations of insects, potentially including those that ravage agricultural crops and transmit... more
Using CRISPR technology for conditional gene regulation  SCIENCE DAILY · 4 weeks
CRISPR allows scientists to precisely target and edit DNA within living cells, which could help them correct anomalies that cause inherited diseases. A team has now developed a method to use CRISPR/Cas9 technology to... more
Giving Cas9 an 'on' switch for better control of CRISPR gene editing  SCIENCE DAILY · 5 days
Scientists have created an 'on' switch for CRISPR-Cas9 that allows it to be turned on in select cells only, specifically those that have a... more
NYSCF announce partnership with Ngene to develop new disease treatments  NEWS MEDICAL · 6 days
The New York Stem Cell Foundation Research Institute today announced a partnership with Ngene Therapeutics Inc. to develop new disease treatments that leverage human stem cell research and... more
Should researchers engineer a spicy tomato?  SCIENCE DAILY · 1 week
With the latest gene-editing techniques, it could be possible, although challenging, to make a tomato produce capsaicinoids (the compounds that make peppers spicy), researchers argue. Their objective isn't to start a hot, new culinary fad --... more
CRISPR-Cas9 circular permutants can sense and respond to viral proteases  NEWS MEDICAL · 5 days
Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of... more
[Editors' Choice] After the CRISPR-Cas9 cut: Predicting generated mutations  Science Magazine · 4 weeks
Analysis of synthetic guide RNA targets yields prediction algorithms for expected mutations following genome editing. more
New CRISPR-Cas9 variants can respond to viral proteases  PHYS.ORG · 5 days
Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse... more
Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets  NEWS MEDICAL · 4 weeks
Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announces that it has entered into... more
Unmuting large silent genes lets bacteria produce new molecules, potential drug candidates  SCIENCE DAILY · 2 weeks
By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the have unlocked several large gene clusters for new natural... more
News of the first gene-edited babies ignited a firestorm  SCIENCE-NEWS · 4 weeks
A researcher in China announced he created two babies using CRISPR. Many scientists questioned the study’s ethics and medical necessity. more
Researchers uncover new mechanism of gene regulation involved in tumor progression  SCIENCE DAILY · 1 week
Researchers have discovered a new mechanism controlling the expression of a set of genes important for cell proliferation and tumor progression. Their research responds to a... more
Novel gene therapy could dampen drug-induced side effect in Parkinson's patients  NEWS MEDICAL · 4 days
A Michigan State University researcher has received a $2.8 million federal grant to develop a gene therapy that could reduce and possibly eliminate a frustrating side... more
Is Anyone Out There? New SETI Tool Keeps Track of Alien Searches  LIVE SCIENCE · 2 days
With research on extraterrestrial life continuing across the world, a noted researcher from the SETI Institute launched a new tool to help researchers keep... more
Is Anyone Out There? New SETI Tool Keeps Track of Alien Searches  SPACE.COM · 5 days
With research on extraterrestrial life continuing across the world, a noted researcher from the SETI Institute launched a new tool to help researchers keep... more
Researchers launch clinical trial to develop breath test for multiple cancers  NEWS MEDICAL · 2 weeks
Researchers have launched a clinical trial to develop a breath test, analyzing molecules that could indicate the presence of cancer at an early stage. more
Scientists provide new insight on how gene expression is controlled  PHYS.ORG · 1 week
Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife. more
Scientists provide new insight on how gene expression is controlled  SCIENCE DAILY · 1 week
Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a new study. more
Researchers uncover new mechanism of gene regulation involved in tumor progression  PHYS.ORG · 6 days
Genes contain all the information needed for the functioning of cells, tissues and organs. Gene expression, meaning when and how the genes are read and executed,... more
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