A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.... NEWS MEDICAL · 2 months
Researchers develop new method to boost efficiency of CRISPR gene editing in DMD  NEWS MEDICAL · 2 weeks
Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study... more
Using more-specific 'genetic scissors' may avoid problems associated with gene editing  SCIENCE DAILY · 17 hours
A new study suggests that there could be a way to bypass barriers to making CRISPR gene-editing treatments a viable option. Researchers found that using more-precise... more
CRISPR gene editing: Why we need Slow Science  PHYS.ORG · 3 days
In a newly published article in Nature, a group of prominent scientists and ethicists have called for a moratorium on clinical research using CRISPR/Cas9 gene editing. more
Manipulating gene expression in neurons with CRISPR  SCIENCE DAILY · 4 weeks
Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. This technique paves the way for researchers to probe genetic influences on brain health and disease in model organisms that... more
Scientists find method to boost CRISPR efficiency  SCIENCE DAILY · 2 weeks
Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases. more
Scientists find method to boost CRISPR efficiency  PHYS.ORG · 2 weeks
Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases. more
CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells  Science Magazine · 2 weeks
Mutations in the dystrophin gene cause Duchenne muscular dystrophy (DMD), which is characterized by lethal degeneration of cardiac and skeletal... more
Using more-specific 'genetic scissors' may avoid problems associated with gene editing  PHYS.ORG · 1 day
Recent studies have suggested a potential barrier to making CRISPR gene-editing treatments a viable option for inherited blood-related disorders such as sickle cell anemia, thalassemia, and... more
Distorted, stretched DNA may increase risk of off-target changes with CRISPR-Cas9  PHYS.ORG · 3 weeks
Distortions to DNA, which occur routinely during gene expression and other cellular processes, could lead to off-target changes to the genome when using CRISPR-Cas9, a new... more
New strategy improves efficiency of CRISPR-Cas9 genome editing  PHYS.ORG · 4 weeks
The efficiency of CRISPR genome editing tools targeted to the site of interest by Cas9 nucleases varies considerably and a new CMP-fusion strategy, called CRISPR-chrom, enhances the activity up to several-fold. CRISPR-chrom... more
Boyce Thompson Institute launches new Plant Genome Editing Database  PHYS.ORG · 3 weeks
Recently developed gene editing tools like CRISPR/Cas enable plant scientists to figure out the functions of myriad plant genes. While these studies could eventually lead to the creation of crops... more
Scientists sharpen their molecular scissors and expand the gene editing toolbox  SCIENCE DAILY · 4 weeks
Scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the editor proteins in the cells in what... more
Gene editing regulations to be tightened  NEWS MEDICAL · 2 days
Last week a group of scientists from across the globe came together to sign a moratorium on gene editing in humans. more
Scientists sharpen their molecular scissors and expand the gene editing toolbox  PHYS.ORG · 4 weeks
Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the... more
China tightens its regulation of some human gene editing, labeling it ‘high-risk’  Science Magazine · 3 weeks
Response to babies created used genome editor CRISPR is “reasonable,” some scientists say, though concerns remain more
Experts call for halt to gene editing that results in 'designer babies'  REUTERS · 1 week
Top scientists and ethicists from seven countries on Wednesday called for a global moratorium on gene editing of human eggs, sperm or embryos that... more
Call for halt to human gene editing and designer babies experiments  NEWS MEDICAL · 5 days
Powerful gene editing tools could soon face a global regulations on their use on human embryos, sperms or eggs. more
Checking DNA base editor's mistakes and tricks to reduce them  nanowerk · 3 weeks
Digenome-seq technique reveals the accuracy of CRISPR-based editing tool that changes DNA letter A to G. more
Gene editing and designer babies experiments face global moratorium  NEWS MEDICAL · 2 days
Powerful gene editing tools could soon face a global regulations on their use on human embryos, sperms or eggs. more
Turning off HSF5 gene leads to less and poorer quality sperm  PHYS.ORG · 3 weeks
In research on zebrafish, Örebro researchers have identified a gene that is essential for producing sperm. Results show that fewer and poorer quality sperm are produced... more
WHO panel calls for registry of all human gene editing research  REUTERS · 3 days
It would be irresponsible for any scientist to conduct human gene-editing studies in people,... more
With nanotubes, genetic engineering in plants is easy-peasy  nanowerk · 4 weeks
Inserting or tweaking genes in plants is more art than science, but with a new technique, scientists could make genetically engineering any type of plant - in particular, gene editing with CRISPR-Cas9... more
Using CRISPR to regulate genes in the rat brain  NEWS MEDICAL · 4 weeks
Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. Described in eNeuro, this technique paves the way for researchers to probe genetic influences on brain... more
A CRISPR spin-off causes unintended typos in DNA  SCIENCE-NEWS · 2 weeks
One type of CRISPR gene editor makes frequent and widespread mistakes, studies in mice and rice reveal. more
Robust and specific gene regulation tool developed for primary brain neurons  SCIENCE DAILY · 4 weeks
A powerful neuroscience tool is available to investigate brain development, mechanisms of memory and learning, and brain dysregulation in neuropsychiatric diseases like addiction, depression, schizophrenia and... more
Illuminating the genome  PHYS.ORG · 2 weeks
The CRISPR/Cas9 system has been causing ripples in the scientific community ever since its mechanisms were reported in 2012. Commonly referred to as a genome editing tool, many scientists have found different applications for the scissor-like properties of the Cas9-protein.... more
With nanotubes, genetic engineering in plants is easy-peasy  PHYS.ORG · 4 weeks
Inserting or tweaking genes in plants is more art than science, but a new technique developed by University of California, Berkeley, scientists could make genetically engineering any type of plant—in particular, gene... more
Researchers discover a new mechanism used by bacteria to evade antibiotics  PHYS.ORG · 2 weeks
As bacteria continue to demonstrate powerful resilience to antibiotic treatments—posing a rising public health crisis involving a variety of infections—scientists continue to seek a better understanding... more
The gene-edited twins born in China may have altered cognition and memory  NEWS MEDICAL · 4 weeks
A new study has fuelled further concerns over the controversial gene-editing experiment that was performed in China last year. more
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