Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations.... NEWS MEDICAL · 2 months
DNA as you've never seen it before, thanks to a new nanotechnology imaging method  nanowerk · 15 hours
Nanochannel technology allows scientists to conduct an experiment never attempted before: map all the locations where DNA replication begins simultaneously... more
Principles of genome folding into topologically associating domains  Science Magazine · 2 weeks
Understanding the mechanisms that underlie chromosome folding within cell nuclei is essential to determine the relationship between genome structure and function. The recent application of "chromosome conformation capture" techniques has revealed that... more
Digging ancient signals out of modern human genomes  SCIENCE DAILY · 3 weeks
Trying to find ancient DNA, let alone prove that the ancient DNA is ancestral to a population living today, is extremely challenging. A new study adds to this understanding by reconstructing artificial... more
Researchers aim to demystify complex ag water requirements for Produce Safety Rule  SCIENCE DAILY · 4 weeks
In an effort to ensure the safety of fresh fruits and vegetables for consumers, researchers are helping to explain complex federal food safety rules... more
Pediatric Cell Atlas needed for better understanding of children’s health and illnesses  NEWS MEDICAL · 4 weeks
Research efforts to comprehensively map adult human cells are in progress. But in a Perspective publishing March 28 in the journal Developmental Cell, researchers... more
DNA copying machine a master of resource recycling  PHYS.ORG · 3 weeks
Researchers at the University of Wollongong's (UOW) Molecular Horizons initiative have shed new light on how an important but not well understood protein goes about its vital role of reducing errors and... more
Unjamming the genome after DNA damage  SCIENCE DAILY · 3 weeks
A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the... more
Scientists identify two, extremely rare genetic variants linked to Alzheimer disease  NEWS MEDICAL · 4 weeks
Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time. more
Injected DNA nanodevice as light-activated remote control for cells  nanowerk · 1 week
Researchers used near-infrared light and an injected DNA nanodevice to guide stem cells to an injury, which helped muscle tissue regrow in mice. more
DNA rearrangement may predict poor outcomes in multiple myeloma  NEWS MEDICAL · 2 days
A certain type of DNA marker predicts poor outcomes in multiple myeloma, researchers at Winship Cancer Institute, Emory University have found. more
Clear sight in the data fog with PAGA  SCIENCE DAILY · 2 weeks
Experimental molecular assays with single-cell resolution generate big and complex data. Researchers are now presenting their computer algorithm PAGA. They create data-driven, easily interpretable maps that reveal cellular processes and fates in... more
'Longevity gene' responsible for more efficient DNA repair  SCIENCE DAILY · 2 days
Researchers found that the gene sirtuin 6 (SIRT6) is responsible for more efficient DNA repair in species with longer lifespans. The research illuminates new targets for anti-aging interventions and could help prevent... more
Medical News Today: Benefits and uses of B-complex vitamins  MNT · 3 weeks
Vitamin B complex refers to the eight B vitamins. In this article, we take a closer look at each of these vitamins, the benefits of B-complex supplements, who should use... more
Novel strategy to ameliorate symptoms of mitochondrial disease  NEWS MEDICAL · 3 weeks
Diseases affecting mitochondria, the powerhouses of our cells, are often caused by mutations in the mitochondrial DNA. Symptoms of such mitochondrial diseases in mice can be ameliorated by increasing their levels of... more
Mechanistic insights into the SNARE complex disassembly  Science Magazine · 2 weeks
NSF (N-ethylmaleimide–sensitive factor) and α-SNAP (α–soluble NSF attachment protein) bind to the SNARE (soluble NSF attachment protein receptor) complex, the minimum machinery to mediate membrane fusion, to form a 20S complex, which disassembles the... more
Programmable 'Legos' of DNA and protein building blocks create novel 3D cages  nanowerk · 3 weeks
DNA nanotechnology uses DNA molecules as programmable 'Legos' to assemble structures with a control not possible with other molecules. more
Indian satellite destruction created 400 pieces of debris, endangering ISS: NASA  PHYS.ORG · 3 weeks
The head of NASA on Monday branded India's destruction of one of its satellites a "terrible thing" that had created 400 pieces of orbital debris and... more
Shifting Brexit date gives map-makers a headache  PHYS.ORG · 2 weeks
In or out? The repeated delays to Brexit are a nightmare for map makers and guidebook printers who have to decide how to depict Britain's relationship with the European Union. more
Researchers aim to demystify complex ag water requirements for Produce Safety Rule  PHYS.ORG · 4 weeks
In an effort to ensure the safety of fresh fruits and vegetables for consumers, Cornell University's Produce Safety Alliance is helping to explain complex... more
Researchers create molecular-scale Rubik's Cube  PHYS.ORG · 4 weeks
Ever since Ernő Rubik invented the Rubik's Cube in 1974, the mathematical puzzle has tested the brains and patience of people of all ages. Two researchers working on molecular manipulation at the Laboratory of Atomic Materials (LAM) set... more
Unjamming the genome after DNA damage: A gene regulatory multi-tool has yet another function  PHYS.ORG · 3 weeks
A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has... more
Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies  Science Magazine · 2 weeks
While poly(ADP-ribosyl)ation (PARylation) plays an important role in DNA repair, the role of dePARylation in DNA repair remains elusive. Here, we report that a novel small molecule identified... more
How jackdaws remember what they did where and when  PHYS.ORG · 1 week
Corvids are capable of cognitive feats that almost resemble those of humans. Neuroscientists at Ruhr-Universität Bochum (RUB) intend to find out how their brain manages to fulfill such complex tasks... more
Scientists release most detailed map of Teton quake fault  PHYS.ORG · 3 weeks
Scientists have completed the most detailed map yet of one of North America's most spectacular geologic faults with the hope of providing a better understanding of the earthquake risk at... more
Interactive heat map shows childhood asthma burden due to traffic-related air pollution across the U.S.  NEWS MEDICAL · 3 weeks
A team of air quality and health researchers led by the Texas A&M Transportation Institute has created a... more
Research uncovers critical RNA processing aberrations in ALS and FTD  NEWS MEDICAL · 4 days
Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontal temporal dementia was published in the April issue of Acta Neuropathologica. more
Clear sight in the data fog with PAGA  PHYS.ORG · 2 weeks
Experimental molecular assays with single-cell resolution generate big and complex data. Researchers at Helmholtz Zentrum München and the Technical University of Munich are now presenting their computer algorithm PAGA. They create data-driven,... more
A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage  NEWS MEDICAL · 3 weeks
A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has... more
Protein complex may help prevent neurodegenerative diseases  PHYS.ORG · 2 weeks
Researchers from the Universities of Konstanz (Germany), Leeds (U.K.) and Stanford (U.S.) have discovered that the nascent polypeptide-associated complex (NAC) prevents the aggregation of proteins associated with several neurodegenerative diseases. The study, "Dual role... more
Ancient DNA reveals new branches of the Denisovan family tree  PHYS.ORG · 2 weeks
It's widely accepted that anatomically modern humans interbred with their close relatives, the Neanderthals and Denisovans, as they dispersed out of Africa. But a study examining DNA fragments... more
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Meteoroid strikes eject precious water from moon
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Attention skills in a nonhuman cooperative breeding species
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