After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center investigated why the complication occurred, performing a molecular analysis of the disease's pathology and mining data to determine the incidence of similar occurrences.... NEWS MEDICAL · 4 weeks
Encephalitis identified as rare toxicity of immunotherapy treatment  SCIENCE DAILY · 4 weeks
Researchers chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies. more
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New lipid signaling target may improve T cell immunotherapy  SCIENCE DAILY · 2 days
T cell immunotherapy uses the immune system to kill cancer cells. To increase the efficacy of this new treatment, researchers aimed to discover a master regulator of T cell fate.... more
CAR-T cells used to target glioblastoma  NEWS MEDICAL · 4 weeks
Immunotherapy is the new weapon against cancers and building upon existing research, a team of researchers from the Massachusetts General Hospital have devised a way to make immunotherapy more effective in a deadly and common form... more
Humic substances extracted from coal can help fight viruses  NEWS MEDICAL · 2 days
Scientists from Russia demonstrated a novel approach leveraging the combination of high-resolution mass spectrometry and chemoinformatics to identify biologically active molecular components of humic substances extracted from coal, and discovered... more
A substance found in brown coal can help combat viruses  PHYS.ORG · 2 days
Scientists from Russia have demonstrated a novel approach leveraging high-resolution mass spectrometry and chemoinformatics to identify biologically active molecular components of humic substances extracted from coal, and discovered... more
Scientists find way to cut nanoparticle toxicity levels  PHYS.ORG · 13 hours
Bioengineers and biophysicists from the National Research Nuclear University MEPhI, the Sechenov First Moscow State Medical University, the Universite de Reims Champagne-Ardenne in France, and the University of Tubingen in Germany have... more
An unexpected developmental hierarchy in a rare disease affecting young children  NEWS MEDICAL · 4 weeks
Langerhans cell histiocytosis is a rare disease affecting primarily young children. While LCH may heal by itself without treatment in some patients, others require intensive chemotherapy... more
Researchers develop new gene editing system that could be used for anticancer immunotherapy  NEWS MEDICAL · 24 hours
Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they... more
New research explains why some cancers don't respond to immunotherapy  NEWS MEDICAL · 2 weeks
New research has uncovered a mechanism thought to explain why some cancers don't respond to a widely used form of immunotherapy called "checkpoint inhibitors" or anti-PD-1. more
Scientists identify new way to target bottleneck for cancer cell growth  NEWS MEDICAL · 4 weeks
The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide... more
Scientists identify propranolol's target in treating rare condition and hemangiomas  SCIENCE DAILY · 3 weeks
The discovery of a new target for the blood-pressure medication propranolol may lead to the development of new and safer therapies for vascular diseases, according to new findings. more
Research using mechanics and physics could predict diseases that 'stress out' cells  nanowerk · 2 days
In new research on the physical behavior of cells undergoing allostatic changes due to local stress, researchers identify patterns that could lead to diagnosis... more
Study finds attractive therapeutic target for treatment of Kennedy's disease and prostrate cancer  NEWS MEDICAL · 2 weeks
A study led by scientists at the Institute for Research in Biomedicine and published in Nature Communications proposes chaperone protein Hps70 as... more
Internet may help diagnose people with rare disorders  NEWS MEDICAL · 2 weeks
A team of researchers at the Wake Forest Baptist Medical Center found that information found on the internet can serve as good means to diagnose individuals who suspect they have a rare... more
Better tools, better cancer immunotherapy  SCIENCE DAILY · 2 weeks
Researchers have developed an important new tool towards producing therapies for cancer patients using the patient's own cells more
Machine learning models help clinicians identify people who need advanced depression care  SCIENCE DAILY · 11 hours
Researchers have created decision models capable of predicting which patients might need more treatment for their depression than what their primary care provider can... more
Finding a cause of neurodevelopmental disorders  SCIENCE DAILY · 3 weeks
Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a mutation in a complex of proteins could... more
Scientists identify hereditary pancreatic cancer risk mutation  NEWS MEDICAL · 1 week
Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers. more
Novel imaging approach has potential to identify patients with CAD  SCIENCE DAILY · 4 weeks
Researchers have developed a novel imaging approach that has the potential to identify patients with coronary disease without administration of drugs or contrast dye and within a short... more
Researchers advocate for using local norms instead of national standards to identify academically gifted students  PHYS.ORG · 1 week
"Who are the highest-performing students in my school?" This is the question K-12 school administrators should be asking... more
Medical News Today: Everything you need to know about broken ribs  MNT · 5 hours
Broken ribs are a common injury following an accident or fall. In this article, learn about how to identify the symptoms and what to expect from... more
Cyborg organoids offer rare view into early stages of development  SCIENCE DAILY · 2 weeks
Researchers have grown simplified organs known as organoids with fully integrated sensors. These so-called cyborg organoids offer a rare glimpse into the early stages of organ development. more
Largest genomic analysis could help improve treatment for Merkel cell carcinoma patients  NEWS MEDICAL · 12 hours
Merkel cell carcinoma is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each year in the United States. more
Antibiotic treatment can slow down skin lymphoma  NEWS MEDICAL · 4 weeks
New research from the LEO Foundation Skin Immunology Research Center at the University of Copenhagen shows, surprisingly, that antibiotics inhibit cancer in the skin in patients with rare type of lymphoma. more
Advanced tools could lead to better cancer immunotherapy  NEWS MEDICAL · 1 week
In the journal Science Immunology, researchers from DTU Health Technology and Jacobs University in Bremen have just published their cutting-edge research demonstrating advancement in detection of a certain type of immune cells,... more
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