Scientists have zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older. These findings provide a more expanded and in-depth picture of the genetic contributions to AMD, and they present new pathways for treatment development.... SCIENCE DAILY · 7 days
Researchers identify new genes linked with age-related macular degeneration  NEWS MEDICAL · 4 weeks
A new study, published in Clinical Epigenetics, identifies genes associated with Age-related Macular Degeneration that could represent new targets for future drug development. more
Defective molecular master switch could lead to age-related macular degeneration  NEWS MEDICAL · 4 weeks
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration. more
New genes associated with the leading cause of blindness  SCIENCE DAILY · 4 weeks
A new study identifies genes associated with Age-related Macular Degeneration (AMD) that could represent new targets for future drug development. more
NIH scientists zero in on genes associated with AMD  NEWS MEDICAL · 6 days
National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration, a leading cause of vision loss and blindness among people age 65... more
Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration  Science Magazine · 5 days
Choriocapillary loss is a major cause of neovascular age-related macular degeneration (NV-AMD). Although vascular endothelial growth factor (VEGF) blockade for NV-AMD has shown beneficial outcomes, unmet... more
Faulty molecular master switch may contribute to AMD  SCIENCE DAILY · 4 weeks
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD). more
NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms  NEWS MEDICAL · 3 weeks
Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI)... more
Obstructive sleep apnea linked to inflammation, organ dysfunction  SCIENCE DAILY · 6 days
Voyagers no longer embark in search of the storied Fountain of Youth, but the quest for longevity is still very much alive for researchers. Chronological age -- the passing of time one... more
Big data opens door for characterizing immunity-related genome in Japanese population  NEWS MEDICAL · 3 weeks
Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called... more
HIV drug could treat Alzheimer's, age-associated disorders  SCIENCE DAILY · 2 weeks
Researchers have found that blocking retrotransposon activity with a generic HIV/AIDS medication significantly reduces age-related inflammation in old mice and senescent human cells, providing hope for treating age-associated disorders. more
Study reveals new genes and biological pathways linked to osteoarthritis  NEWS MEDICAL · 4 weeks
In the largest genetic study of osteoarthritis, an international team of scientists including researchers from the University of Sheffield, have uncovered 52 new genetic changes linked to the... more
Study finds early home and family factors linked to development of obesity  NEWS MEDICAL · 6 days
A new 21-year longitudinal study identified multiple risk factors related to the family and home environment associated with the timing and faster increase in... more
Blood-brain barrier disruption could lead to age-related cognitive decline  NEWS MEDICAL · 3 days
As our brains age, we become more forgetful, more tired and less able to do the cognitive gymnastics of our youth. more
Rapid progression of age-related diseases may result from formation of vicious cycles  NEWS MEDICAL · 6 days
Biologist Aleksey Belikov from the Moscow Institute of Physics and Technology has proposed that rapid progression of age-related diseases may result from the formation... more
Genetic study reveals possible new routes to treating osteoarthritis  SCIENCE DAILY · 4 weeks
In the largest genetic study of osteoarthritis to date, scientists have uncovered 52 new genetic changes linked to the disease, which doubles the number of genetic regions associated with the... more
Overlapping genomic regions underlie canine fearfulness and human mental disorders  SCIENCE DAILY · 4 weeks
Researchers have identified two novel anxiety-related genomic regions in German Shepherd dogs. The region associated with fearfulness corresponds with the locus of human chromosome 18, which is associated... more
USC researchers use AI to identify blood-based markers of Alzheimer's disease  NEWS MEDICAL · 3 weeks
Nearly 50 million people worldwide have Alzheimer's disease or another form of dementia. While age is the greatest risk factor for developing the disease, researchers believe... more
Scientists find genes with large effects on head and brain size  SCIENCE DAILY · 4 weeks
The size of children's heads is not only related to the growth of their skull, but also their brain. A genome-wide analysis now reports the largest... more
Obesity-related cancers are rising rapidly among adolescents in the US  NEWS MEDICAL · 2 weeks
A new study has found that the incidence of obesity-related cancers in the US is rising faster among millennials than it is among older age groups. more
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration  Science Magazine · 5 days
Injured axons undergo a controlled, self-destruction process, known as Wallerian degeneration. However, the underlying mechanism remains elusive. Using the Drosophila wing nerve... more
The interplay between relationships, stress, and sleep  SCIENCE DAILY · 2 weeks
A new study documents how the quality of a person's romantic relationship and the life stress he or she experiences at two key points in early adulthood (at age 23 and 32) are related... more
Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis  NEWS MEDICAL · 3 weeks
The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is... more
Study shows how relationships, stress affect sleep  NEWS MEDICAL · 2 weeks
A new Personal Relationships study documents how the quality of a person's romantic relationship and the life stress he or she experiences at two key points in early adulthood (at age 23 and 32)... more
Researchers describe first case of patient affected by dysfunctions in SLC28 gene family  NEWS MEDICAL · 2 weeks
A research team has described the first case of a patient affected by dysfunctions in a nucleoside transporter of the SLC28 gene... more
Onset of migraine with aura before age of 50 not linked to risk of ischemic stroke  NEWS MEDICAL · 4 weeks
Migraine with aura was associated with an increased risk of ischemic stroke in the Atherosclerosis Risk... more
What's age got to do with it?  SCIENCE DAILY · 4 days
It's often said: it's not how old you are, it's how old you feel. New research shows that physiological age is a better predictor of survival than chronological age. more
Researchers gain new insights into aging-related changes in upper lip  NEWS MEDICAL · 3 weeks
Plastic surgeons have long debated the mechanisms aging-related changes in the face: Are they related more to "deflation" or "sagging"? A new study helps settle the debate, showing... more
Childhood lead exposure linked to poor adult mental health  SCIENCE DAILY · 4 weeks
Lead exposure in childhood appears to have long-lasting negative effects on mental health and personality in adulthood, according to a study of people who grew up in the era of... more
DDT exposure linked to increased breast cancer risk for all women through age 54  NEWS MEDICAL · 5 days
All women exposed to high levels of DDT are at increased risk for breast cancer through age 54, but the... more
Researchers identify genes that make Staphyloccocus bacteria resistant to treatment  NEWS MEDICAL · 1 week
A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent. more
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