Researchers at The University of Texas MD Anderson Cancer Center have discovered that malignant rhabdoid tumors, a rare pediatric cancer without effective treatments, may be sensitive to drugs that block the cancer cell's ability to dispose of misfolded proteins.... NEWS MEDICAL · 6 days
Researchers uncover novel mechanism and potential new therapeutic target for Alzheimer’s  NEWS MEDICAL · 6 days
Researchers at Wake Forest Baptist Health have identified a novel mechanism and potential new therapeutic target for Alzheimer's disease. more
FSU study breaks new ground in the battle against malignant pediatric brain cancers  NEWS MEDICAL · 3 weeks
Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new... more
Researchers identify marker protein that offers both diagnostic and therapeutic function  NEWS MEDICAL · 4 weeks
Of all gastrointestinal cancers, pancreatic cancer is one of the most aggressive. Because of this, it has a very low 5-year survival rate of just 5%... more
New findings could provide novel approach to target and destroy cancer cells  NEWS MEDICAL · 1 week
An unexpected finding in pre-clinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing... more
New therapeutic target for graft-vs-host disease could make bone marrow transplant safer  SCIENCE DAILY · 3 weeks
Graft-versus-host disease (GVHD) is a major complication of bone marrow transplant, a potentially curative treatment for patients with blood-borne cancers such as leukemia and... more
Drug compound could be next-generation treatment for aggressive form of leukemia  SCIENCE DAILY · 3 weeks
Researchers are developing a series of drug compounds that have shown promise in treating acute myeloid leukemia, an aggressive blood cancer that is one of the... more
Rare stem cell may be the root of all metastatic cancers  NEWS MEDICAL · 2 weeks
Researchers have discovered a rogue stem cell that could be the cause of all metastatic cancers. The breakthrough could affect all future research projects. more
Targeted treatment shrinks deadly pediatric brain tumors  SCIENCE DAILY · 4 weeks
For children -- whose tiny bodies are still growing -- chemotherapy and radiation treatments can cause lifelong damage. Now, scientists have reported that a targeted therapy that blocks a protein called LSD1 was able... more
Medical News Today: New drug shows promise against several aggressive cancers  MNT · 5 days
Initial trials in humans find that a new drug, tisotumab vedotin, shows significant promise in treating stubborn tumors in several late-stage cancers. more
Immunotherapy appears better than chemotherapy for aggressive type of skin cancer  SCIENCE DAILY · 2 weeks
The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel... more
Researchers discover immune regulator that appears to dictate glioblastoma  NEWS MEDICAL · 3 weeks
Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma progression by shutting down immune surveillance, indicating a potential new... more
Researchers find anti-microRNAs as potential new therapeutic target for type 2 diabetes  NEWS MEDICAL · 1 week
Researchers have shown that targeted silencing of microRNA-132, which is over-expressed in type 2 diabetes, can result in improved insulin secretion and reduced blood... more
Medical News Today: How skin cancer becomes invasive  MNT · 2 weeks
A new study has finally identified a mechanism that allows skin cancer to become aggressive. The discovery also suggests a novel therapeutic approach. more
High-dose radiation therapy improves long-term survival in patients with stage-IV cancers, trial finds  SCIENCE DAILY · 3 weeks
The first report from a phase II, multi-center clinical trial indicates that a newer, more aggressive form of radiation therapy -- stereotactic... more
New drug compounds show promise in treating acute myeloid leukemia  NEWS MEDICAL · 3 weeks
Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one... more
New 3D imaging technique reveals how pancreatic cancers start  SCIENCE DAILY · 3 weeks
A new technique to study tissue samples in 3D has revealed that pancreatic cancers can start and grow in two distinct ways, solving a decades-old mystery of how tumors form.... more
Study shows blindfolds could improve doctors’ leadership in pediatric resuscitation  NEWS MEDICAL · 5 days
Doctors’ leadership in pediatric resuscitation improved most when they wore a blindfold during simulation training more
Blindfolded training could help doctors save young lives  SCIENCE DAILY · 4 days
Doctors have found that pediatric team leaders improve more during resuscitation training if they wear a blindfold. Their findings demonstrate a promising tool for improving training and outcomes in pediatric resuscitation. more
Study outlines research priorities for improving pediatric patient care and safety  NEWS MEDICAL · 4 weeks
In the first study to comprehensively evaluate research priorities for patient safety in pediatrics, St. Jude Children's Research Hospital researchers and collaborators from other children's hospitals... more
A weakness in a rare cancer that could be exploited with drugs  SCIENCE DAILY · 3 days
Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able... more
Watchful waiting in prostate cancer becoming more popular  NEWS MEDICAL · 6 days
In 2010, the US National Comprehensive Cancer Network guidelines suggested that patients with stable and low-risk prostate cancers could be managed with active surveillance or watchful waiting (AS/WW). AS/WW was considered to... more
Method to 'turn off' mutated melanoma  SCIENCE DAILY · 3 weeks
Melanoma is the deadliest form of skin cancer and notorious for its resistance to conventional chemotherapy. Approximately 25 percent of melanoma is driven by oncogenic mutations in the NRAS gene, making it a very attractive therapeutic... more
Shared genetic marker offers new promise in targeting specific ovarian and lung cancers  SCIENCE DAILY · 2 weeks
Two new articles offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two... more
New therapy for aggressive blood cancer discovered  SCIENCE DAILY · 5 days
Acute myeloid leukemia (AML) is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells. Only twenty-five percent of... more
Immunotherapy may be better than chemotherapy for Merkel cell carcinoma  NEWS MEDICAL · 1 week
The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma... more
Breaking new ground in study of malignant pediatric brain tumor  SCIENCE DAILY · 3 weeks
Researchers identified a series of cancer-causing driver gene mutations and discovered that medulloblastoma is perhaps an even more dynamic and variable tumor than expected. more
New footage released of rare giant pangolins in Africa  PHYS.ORG · 5 days
Researchers from a British Zoo on Wednesday released rare footage revealing the secret lives of giant pangolins, considered one of the world's most trafficked mammals. more
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