A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide long-term benefit for patients.... NEWS MEDICAL · 1 month
A previously unknown mechanism could be new therapeutic target for cancer immunotherapy  NEWS MEDICAL · 3 weeks
Researchers at UC have discovered a previously unknown mechanism that could explain the reason behind decreased immune function in cancer patients and could be... more
Potential breakthrough in cancer immunotherapy with gasdermin E  NEWS MEDICAL · 2 weeks
A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present. more
Immunotherapy using 'young cells' offers promising option against cancer  SCIENCE DAILY · 4 days
A new study suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells -- natural killer (NK) cells --... more
Immunotherapy treatment shows promise for some patients with advanced rare cancers  NEWS MEDICAL · 1 week
A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of... more
Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients  NEWS MEDICAL · 6 days
Immunotherapy that involves treating cancer with the body's own immune cells, or those of a matched donor, shows promise in clinical trials... more
Combination of radiation and immunotherapy shows promise for advanced head and neck cancers  NEWS MEDICAL · 1 month
A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity... more
Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests  NEWS MEDICAL · 3 weeks
Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor? more
How to boost immune response to vaccines in older people  SCIENCE DAILY · 1 day
Identifying interventions that improve vaccine efficacy in older persons is vital to deliver healthy aging for an aging population. Immunologists have identified a route for counteracting the age-related... more
New type of adoptive cell therapy could target prostate and pancreatic cancers in humans  NEWS MEDICAL · 3 weeks
In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted... more
NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists  Science Magazine · 1 week
Several immunotherapy approaches that mobilize CD8+ T cell responses stimulate tumor rejection, and some, such as checkpoint blockade, have been... more
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses  Science Magazine · 3 weeks
Currently, there is a huge demand to develop chemoimmunotherapy with reduced systemic toxicity and potent efficacy to combat late-stage cancers... more
YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma  Science Magazine · 1 week
Head-and-neck squamous cell carcinoma (HNSCC) is the sixth most common group of cancers in the world, and patients... more
Inhibiting energy production in immune T-cells allows some tumors to escape treatment  NEWS MEDICAL · 4 weeks
A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says... more
Immunology: Tonsils as a testbed  SCIENCE DAILY · 4 weeks
Biomedical researchers have isolated immune cells from human tonsils obtained following routine surgery, and used them to analyze aspects of the immune response and test the effects of anti-inflammatory agents at the cellular level. more
Scientists find link between immune system and high blood pressure in patients with CKD  NEWS MEDICAL · 4 weeks
Detecting threats, sending out response molecules, and altering gene expression--our immune system works tirelessly day and night to protect us... more
Australian researchers map immune response to coronavirus  REUTERS · 2 weeks
Australian researchers said on Tuesday they have mapped the immune responses from one of country's first coronavirus patients, findings the health minister... more
A high salt intake impairs immune response, study suggests  NEWS MEDICAL · 3 days
A study has shown that a high salt intake inhibits the immune system’s ability to combat bacteria. more
Commonly used mouthwash could make saliva significantly more acidic, change microbes  SCIENCE DAILY · 4 days
The first study looking at the effect of chlorhexidine mouthwash on the entire oral microbiome has found its use significantly increases the abundance of lactate-producing bacteria... more
Immunotherapy combination can shrink viral reservoir in HIV model  NEWS MEDICAL · 2 weeks
Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded. more
Two sides of a coin: Our own immune cells damage the integrity of the blood-brain barrier  SCIENCE DAILY · 4 weeks
Researchers have shown that microglia, a class of immune cells in the brain, regulate the permeability... more
A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer  Science Magazine · 1 week
Neoantigen vaccines have been enthusiastically pursued for personalized cancer immunotherapy while vast majority of neoantigens have no or low immunogenicity.... more
Cumulative doses of oral steroids associated with increased hypertension  NEWS MEDICAL · 6 days
Cumulative doses of oral steroids in patients with chronic inflammatory diseases are associated with increased hypertension (blood pressure) for those who take them regularly, found new research in CMAJ. more
Tapping pre-existing immunity to enhance therapeutic cancer treatment  NEWS MEDICAL · 4 weeks
A new research from the University of Helsinki showed for the first time how the pre-immunization acquired through common childhood vaccines can be used to enhance therapeutic cancer treatment. more
Damaging the tumor blood vessels could be new strategy to treat oral cancer  NEWS MEDICAL · 2 weeks
Researchers at Okayama University have recently published a study in Cells in which they reduced the size of oral cancer tumors by... more
Cancer could potentially be treated with new immunotherapy approach, say researchers  NEWS MEDICAL · 3 days
Researchers have made a discovery about EGR4 that could instigate a new immunotherapy approach to treating cancer. more
Wasan lab develops novel oral formulation to treat systemic fungal infections  NEWS MEDICAL · 5 days
The Wasan Laboratory in the Faculty of Pharmaceutical Sciences at the University of British Columbia in partnership with iCo Therapeutics Inc. (Vancouver BC, Canada) have developed... more
CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea  NEWS MEDICAL · 1 week
Up to $2.86M has been awarded to a research team including Penn State scientists to develop a new oral antibiotic to treat multidrug-resistant gonorrhea,... more
Researchers pinpoint mechanism controlling cell protein traffic  PHYS.ORG · 3 weeks
Cells depend on signaling to regulate most life processes, including cell growth and differentiation, immune response and reactions to various stresses. more
New dug could help significantly improve success rate of cancer immunotherapy  NEWS MEDICAL · 4 weeks
A study led by the University of Southampton, funded by Cancer Research UK, has shown a new drug - originally developed to tackle the scarring of... more
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