A Michigan State University researcher has received a $2.8 million federal grant to develop a gene therapy that could reduce and possibly eliminate a frustrating side effect of a drug commonly prescribed to Parkinson's patients.... NEWS MEDICAL · 4 days
New study describes various gene therapy strategies for treating Parkinson's disease  NEWS MEDICAL · 3 weeks
Parkinson's disease is a neurodegenerative disorder characterized by motor and nonmotor deficits majorly caused by the loss of dopaminergic cells in the Substantia Nigra pars compacta... more
New leukemia drug is more effective and easier to use  SCIENCE DAILY · 4 days
Oncologists have found that a newer targeted drug is significantly more effective than standard therapy for treating elderly patients with chronic lymphocytic leukemia (CLL). The drug is taken... more
Study investigates role of miRNAs in anesthetic-induced myocardial conditioning  NEWS MEDICAL · 3 weeks
Many studies have shown that the mechanism of drug-induced myocardial conditioning is enzyme-mediated through messenger RNA and miRNA regulation. In this study Orriach et al. investigated the role that miRNAs... more
Experts in Parkinson's research propose roadmap for drug trials targeting alpha-synuclein  NEWS MEDICAL · 4 weeks
A recently discovered protein, alpha-synuclein, has become one of the most attractive targets for developing new drugs with the potential to slow down or arrest the... more
Real-time neurofeedback controls Parkinson’s brainwaves  NEWS MEDICAL · 4 weeks
A neurofeedback system enables Parkinson’s disease patients to voluntarily control brainwaves associated with symptoms of the disorder, according to new research published in eNeuro. It remains to be determined whether such a system can provide symptom relief. more
UC San Diego to conduct first U.S. clinical trial of intravenously administered bacteriophage therapy  NEWS MEDICAL · 7 days
The U.S. Food and Drug Administration has accepted an Investigational New Drug application by physician-scientists at University of California San... more
Drug combination has added benefit for patients with melanoma  NEWS MEDICAL · 7 days
The German Institute for Quality and Efficiency in Health Care investigated whether the drug combinations of dabrafenib plus trametinib and of encorafenib plus binimetinib have an added benefit in comparison... more
Surge protector: A novel approach to suppressing therapy-induced tumor growth and recurrence  SCIENCE DAILY · 13 minutes
Dead and dying cancer cells killed by conventional cancer treatments paradoxically trigger inflammation that promotes tumor growth and metastasis. Researchers now describe a novel... more
Study provides information about chemotherapeutic drugs binding to plasma proteins  NEWS MEDICAL · 4 weeks
Chemotherapy is use of drugs to cure a disease but more specifically, it refers to drug therapy for cancer. Cancer chemotherapy can be done with a single drug... more
Edging closer to personalized medicine for patients with irregular heartbeat  SCIENCE DAILY · 4 weeks
Biomedical engineers have determined which patients would benefit the most from a commonly used drug treatment. more
[Editors' Choice] Interfer-ing with immunotherapy-induced autoimmunity  Science Magazine · 6 days
Inhibition of type I IFN prevents autoimmune toxicity while preserving antitumor efficacy of combined cancer vaccine and adoptive cell therapy. more
Medical News Today: Acne: How common drug changes skin microbiome  MNT · 1 week
Severe acne is often treated with isotretinoin, which can have serious side effects. New research sheds light on how the drug works and may be improved. more
Study reveals side effects of breast cancer drug on brain function  NEWS MEDICAL · 3 weeks
A comprehensive study of monkeys given the breast cancer drug letrozole reveals side effects that impact the brain. Published in JNeurosci, the research establishes the common... more
New approach may curb treatment-related skin fibrosis in cancer patients  SCIENCE DAILY · 1 week
A clinical-scientific team specializing in head-and-neck cancer has identified a way to manipulate metabolism to potentially curb skin fibrosis -- a common side effect of radiotherapy affecting quality... more
Drug sponge could minimize side effects of cancer treatment  SCIENCE DAILY · 6 days
Catheters are used today to deliver drugs directly to tumors to avoid broadcasting toxic chemotherapy agents throughout the body. Nevertheless, half of the drug can escape to the rest of... more
Defective glial cells can push neurons toward Parkinson's disease  SCIENCE DAILY · 15 minutes
A team of scientists have discovered that astrocytes are linked to the buildup of a toxic protein that is one the hallmarks of Parkinson's disease. The work suggests an important... more
Targeted treatment slows progression of rare connective tissue tumor  SCIENCE DAILY · 4 weeks
A drug called sorafenib stopped progression of desmoid tumors for 80 percent of patients taking the drug over a two-year period as part of a phase 3 trial. more
Urine drug testing may be important in early phases of addiction treatment  SCIENCE DAILY · 4 weeks
A new study shows that urine drug testing can be a useful tool to treat patients with opioid use disorder in a primary care... more
Scientists uncover how protein clumps damage cells in Parkinson's  SCIENCE DAILY · 4 weeks
Research into the root cause of Parkinson's aims to advance work on a disease-modifying treatment. more
Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets  NEWS MEDICAL · 4 weeks
Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announces that it has entered into... more
Medical News Today: 13 early signs of Parkinson's disease  MNT · 2 weeks
People can sometimes miss the early signs and symptoms of Parkinson's disease, as they can be subtle and sporadic. In this article, we look at 13 signs of Parkinson's disease... more
High court seems likely to side with Merck in Fosamax case  ABC NEWS · 1 week
The Supreme Court seems likely to side with drugmaker Merck in a dispute over the warning label on its bone-strengthening drug Fosamax more
Advanced stem cell approach could help fight Parkinson's disease  NEWS MEDICAL · 4 weeks
Scientists have taken a key step towards improving an emerging class of treatments for Parkinson's disease. more
Study assesses when opioid overdose patients can be safely discharged after naloxone treatment  NEWS MEDICAL · 3 weeks
Naloxone has saved thousands of lives. But can patients be safely discharged from the Emergency Department (ED) just an hour after they... more
13 early signs of Parkinson's disease  MNT · 2 weeks
People can sometimes miss the early signs and symptoms of Parkinson's disease, as they can be subtle and sporadic. In this article, we look at 13 signs of Parkinson's disease to look out for. more
Wireless 'pacemaker for the brain' could offer new treatment for neurological disorders  SCIENCE DAILY · 2 weeks
A new neurostimulator can listen to and stimulate electric current in the brain at the same time, potentially delivering fine-tuned treatments to patients with... more
Drug sponge could minimize side effects of cancer treatment  PHYS.ORG · 7 days
With the help of sponges inserted in the bloodstream to absorb excess drugs, doctors are hoping to prevent the dangerous side effects of toxic chemotherapy agents or even deliver higher... more
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