A Michigan State University researcher has received a $2.8 million federal grant to develop a gene therapy that could reduce and possibly eliminate a frustrating side effect of a drug commonly prescribed to Parkinson's patients.... NEWS MEDICAL · 5 months
Parkinson's: New gene therapy shows promise for prevention  MNT · 2 weeks
Researchers from Japan have tested a new gene therapy against Parkinson's disease using mouse models. Their results suggest that the approach is effective. more
Medical News Today: Parkinson's: New gene therapy shows promise for prevention  MNT · 2 weeks
Researchers from Japan have tested a new gene therapy against Parkinson's disease using mouse models. Their results suggest that the approach is effective. more
At $2.1 Million, New Gene Therapy Is The Most Expensive Drug Ever  NPR · 4 weeks
The Food and Drug Administration approved a new gene therapy for a rare but devastating genetic disorder. The drugmaker says the cost is worth... more
At $2.125 Million, New Gene Therapy Is The Most Expensive Drug Ever  NPR · 4 weeks
The Food and Drug Administration approved a new gene therapy for a rare but devastating genetic disorder. The drugmaker says the cost is worth... more
Medical News Today: Is hair loss a side effect of Adderall?  MNT · 2 weeks
Adderall is a combination drug for the short-term treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Although it is generally a safe and effective drug,... more
Proton therapy results in fewer side effects for many cancer patients  NEWS MEDICAL · 4 weeks
Proton therapy results in fewer side effects than traditional X-ray radiation therapy for many cancer patients, according to a new study led by Washington University School... more
Drug therapy for stable heart failure patients can be simplified by stopping diuretics  NEWS MEDICAL · 3 weeks
Drug therapy for patients with stable heart failure can be simplified by stopping diuretics, according to late-breaking results from the ReBIC-1 trial... more
Patients receiving drug therapy before LVAD implantation have high risk of right-sided heart failure  NEWS MEDICAL · 1 week
Patients with left-sided heart failure who get implanted devices to improve the pumping of their hearts may be more likely... more
New drug regimens improve outcomes for kidney transplant patients  SCIENCE DAILY · 2 weeks
Preliminary results suggest that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens. more
When drug treatment for social anxiety is insufficient  SCIENCE DAILY · 3 weeks
A study group clarified that cognitive therapy maintained its effects more than a year after the end of therapy for patients with a social anxiety disorder even for those who did not... more
Germline gene therapy: Safety  SCIENCE DAILY · 2 weeks
An internationally known embryologist and his son make the case for using gene-editing tools to prevent inherited disease, in a new editorial. The authors push back against recent calls for a moratorium on germline gene editing, following the revelation last... more
Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism  Science Magazine · 6 days
The human gut microbiota metabolizes the Parkinson’s disease medication Levodopa (l-dopa), potentially reducing drug availability and causing side effects. However, the organisms, genes, and... more
[Reviews] Supercharging adoptive T cell therapy to overcome solid tumor-induced immunosuppression  Science Magazine · 2 weeks
The development of new cancer immunotherapies including checkpoint blockade and chimeric antigen receptor (CAR) T cell therapy has revolutionized cancer treatment. CAR T cells have shown... more
Medical News Today: Cancer: Proton therapy has fewer side effects than X-ray radiation  MNT · 3 weeks
A first-of-its-kind study compares the cure rates and side effects of proton therapy and X-ray radiation for people with various forms of... more
New gene editor harnesses jumping genes for precise DNA integration  PHYS.ORG · 7 days
A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and... more
Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer  NEWS MEDICAL · 2 weeks
Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced... more
Patients with bipolar disorder are seven times more likely to develop Parkinson's  NEWS MEDICAL · 4 weeks
A new study has found that patients with bipolar disorder are seven times more likely to develop Parkinson’s disease. more
New immunosuppressive regimens may improve outcomes for kidney transplant patients  NEWS MEDICAL · 2 weeks
Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant... more
Three-drug combination could be effective therapy for people with advanced melanoma  NEWS MEDICAL · 2 weeks
A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced... more
Why lack of sleep is bad for your heart  SCIENCE DAILY · 4 weeks
People who sleep fewer than 7 hours per night have lower levels of gene-regulating molecules, or microRNAs, which help dampen down inflammation in cells and support vascular health. more
Nerve stimulation therapy could help patients with the most common type of stroke  NEWS MEDICAL · 4 weeks
Research led by a UCLA scientist found that a new nerve stimulation therapy to increase blood flow could help patients with the... more
New genetic weapons challenge sickle cell disease  SCIENCE DAILY · 2 weeks
Researchers advancing gene-editing techniques to help patients with sickle cell disease discover an unexpected boost in fetal hemoglobin production, which mutes the effect of the disease. more
MOF-encapsulated DNA for gene therapy  nanowerk · 6 days
A critical challenge in gene therapy is the safe and effective delivery of genetic materials across cell membranes into target cells. Although viral systems have been the most effective method for delivering genetic matter into cells, they pose... more
Gut microbes eat our medication  SCIENCE DAILY · 5 days
Researchers have discovered one of the first concrete examples of how the microbiome can interfere with a drug's intended path through the body. Focusing on levodopa (L-dopa), the primary treatment for Parkinson's disease, they identified which bacteria out... more
Scientists achieve first observation of three-dimensional quantum Hall effect  nanowerk · 7 days
In this study, researchers discovered that the carrier density wave induced by electron-electron interaction is the key factor for the appearance of 3D quantum Hall effect. Electrons in such a... more
[Research Articles] Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates  Science Magazine · 4 weeks
Liver-directed gene therapy for the coagulation disorder hemophilia showed safe and effective results in clinical trials using adeno-associated viral vectors to replace a functional... more
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