Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.... NEWS MEDICAL · 4 days
VISTA checkpoint implicated in pancreatic cancer immunotherapy resistance  SCIENCE DAILY · 4 days
Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers. more
Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice  NEWS MEDICAL · 4 weeks
Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in... more
Researchers identify potential target for new breast cancer treatments  NEWS MEDICAL · 4 weeks
Researchers from the School of Basic & Medical Biosciences have identified a potential target that could lead to new treatments for triple negative breast cancer. more
How breast cancer avoids immune system detection  SCIENCE DAILY · 4 weeks
Researchers analyzed data from more than 1,000 breast cancer patients and found that breast cancer behaves differently than other cancers that are currently treated with immunotherapy. They identified seven clusters of breast cancer patients... more
First patient enrolled in pancreatic cancer clinical trial  NEWS MEDICAL · 1 week
The Henry Ford Cancer Institute announced today it has enrolled the first patient in a new clinical trial to test the effectiveness of using precise, higher dose MRI-guided radiation therapy to treat... more
MUSC researchers identify potential therapeutic target for lung fibrosis  NEWS MEDICAL · 4 weeks
In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or... more
FSU researchers discover how breast cancer evades immune system detection  NEWS MEDICAL · 4 weeks
Recent breakthroughs in immunotherapy are making a huge difference in treating some forms of cancer, especially metastatic cancer. But breast cancer has proven a tricky foe for this... more
Researchers zero in on potential therapeutic target for diabetes, associated diseases  SCIENCE DAILY · 4 weeks
A recent study shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target... more
Uncovering more options in cancer immunotherapy  SCIENCE DAILY · 5 days
If scientists want to boost immune cells' ability to kill cancer cells, then vast libraries of small molecules are potentially available. A new paper shows a platform to sort through them, plus validation. One of the... more
Aggressive prostate cancer and hereditary breast cancer  SCIENCE DAILY · 6 days
The study has potential implications for families with members suffering from these types of tumours who are at an increased risk of developing cancer. more
Metal-based chemotherapy enhances the effect of cancer immunotherapy  NEWS MEDICAL · 4 weeks
Due to their powerful tumor-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) effect even... more
Medical News Today: Can fasting help fight cancer?  MNT · 1 day
There are many benefits to fasting. It may even play a role in the prevention and treatment of cancer. There are also some potential risks to be aware of. Learn more about... more
MD Anderson Cancer Center and Nanobiotix collaborate to expand clinical development of NBTXR3  NEWS MEDICAL · 1 week
The University of Texas MD Anderson Cancer Center and Nanobiotix today announced a large-scale, comprehensive clinical research collaboration to evaluate innovative strategies for treating patients with... more
New approach may curb treatment-related skin fibrosis in cancer patients  SCIENCE DAILY · 1 week
A clinical-scientific team specializing in head-and-neck cancer has identified a way to manipulate metabolism to potentially curb skin fibrosis -- a common side effect of radiotherapy affecting quality... more
Medical News Today: Triple-negative breast cancer responds to new dual-target therapy  MNT · 1 week
An experimental therapy that targets two growth pathways reduced cancer cell proliferation and spread in mice with triple-negative breast cancer. more
Potential therapeutic target for amyotrophic lateral sclerosis  SCIENCE DAILY · 3 hours
New research has revealed that the protein TDP-43 regulates a gene called Stathmin2 (STMN2). STMN2 shows promise as a therapeutic target and could be the first biomarker ALS, which is extremely difficult to diagnose... more
[Editors' Choice] Interfer-ing with immunotherapy-induced autoimmunity  Science Magazine · 6 days
Inhibition of type I IFN prevents autoimmune toxicity while preserving antitumor efficacy of combined cancer vaccine and adoptive cell therapy. more
GE Healthcare and VUMC announce partnership to enable safer, more precise cancer immunotherapies  NEWS MEDICAL · 1 week
GE Healthcare and Vanderbilt University Medical Center today announced a five-year partnership to enable safer and more precise cancer immunotherapies. Multiple diagnostic... more
Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma  NEWS MEDICAL · 4 weeks
A team of Russian scientists identified the role of the interleukin-6 molecule in the development of allergic asthma. Now it... more
Researchers identify multiple new subtypes of most common childhood cancer  NEWS MEDICAL · 1 day
Like cartographers completing a map, investigators have identified multiple new subtypes of the most common childhood cancer--research that will likely improve the diagnosis and treatment of high-risk patients. more
Genome offers clues to esophageal cancer disparity  SCIENCE DAILY · 4 weeks
A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds. It suggests a possible target for prevention strategies,... more
DNA origami: A precise measuring tool for optimal antibody effectiveness  SCIENCE DAILY · 1 day
Using DNA origami -- DNA-based design of precise nanostructures -- scientists have been able to demonstrate the most accurate distance between densely packed antigens in order to get... more
DNA origami: A precise measuring tool for optimal antibody effectiveness  PHYS.ORG · 14 hours
Scientists at Karolinska Institutet, Sweden, in collaboration with researchers at University of Oslo, Norway, have demonstrated the most accurate distance between densely packed antigens in order to get... more
Aggressive prostate cancer linked to hereditary breast cancer, confirms study  NEWS MEDICAL · 6 days
Aggressive prostate cancer, one of the leading causes of cancer deaths in men, is associated with BRCA2 mutations, which are also linked to hereditary breast cancer, ovarian cancer... more
Scientists demonstrate potential of imaging technique based on physical properties of tumors  NEWS MEDICAL · 1 week
A team of physicists at the Institut Lumière Matière, in collaboration with the Cancer Research Center of Lyon, has demonstrated the potential, for oncology,... more
Sex differences identified in deadly brain tumors  SCIENCE DAILY · 2 weeks
More males get, and die of, the deadly brain cancer glioblastoma than females. A team of researchers has identified distinct molecular signatures of glioblastoma in men and women that help explain disparities in patients'... more
Dementia: New culprit and potential treatment target  SCIENCE DAILY · 1 day
A study shows people with the worst memory problems also had the most leakage in their brain's blood vessels -- regardless of whether abnormal proteins amyloid and tau were present. more
A compound being developed to treat eye disease also kills leukemia cells  SCIENCE DAILY · 4 weeks
An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating... more
Traditional and new imaging methods used for prostate cancer diagnosis  NEWS MEDICAL · 3 weeks
Prostate cancer is the second prevent type of cancer that exists. Prostate cancer is usually a slowly progressing disease but it can sometimes manifest as an aggressive cancer.... more
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