Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.... NEWS MEDICAL · 5 months
Study: One-third of pancreatic cancer patients miss out on treatment that may extend survival  NEWS MEDICAL · 3 weeks
Despite potential for prolonging survival with treatment, one-third of patients with metastatic pancreatic cancer do not see a medical oncologist,... more
Special fibroblasts help pancreatic cancer cells evade immune detection  SCIENCE DAILY · 4 days
A subpopulation of fibroblasts called apCAFs can interact with the immune system to help pancreatic cancer cells avoid detection. Understanding how they work can be key in developing therapeutics for... more
PCRF awards £1.2M grants for new research projects tackling pancreatic cancer  NEWS MEDICAL · 3 weeks
Seven innovative research projects tackling pancreatic cancer have been awarded grants totalling £1.2M by the UK medical research charity, Pancreatic Cancer Research Fund. more
Scientists identify potential target for Parkinson's treatment  NEWS MEDICAL · 6 days
An international research team led by scientists at the University of Alabama at Birmingham has identified a potential target for therapeutics that might help slow the progression of Parkinson's disease. more
IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer  NEWS MEDICAL · 3 weeks
A team of researchers from Indiana University and Memorial Sloan Kettering Cancer Center have been awarded a $4.1 million National Cancer Institute "Cancer Moonshot" grant to... more
Using molecular biomarkers to guide the choice of therapies for metastatic pancreatic cancer  NEWS MEDICAL · 1 week
A new pilot study demonstrated the feasibility of using molecular tumor markers as the basis for selecting the chemotherapeutic agents to use... more
Alex Trebek shares 'mind-boggling' pancreatic cancer update  ABC NEWS · 3 weeks
"Jeopardy!" host Alex Trebek says his doctors say he's in "near remission" of advanced pancreatic cancer and his response to the treatment is "kind of mind-boggling." more
Potential therapeutic target for sepsis  SCIENCE DAILY · 3 weeks
Scientists have identified a potential new therapeutic target for sepsis. more
Native Hawaiians have highest risk for pancreatic cancer, study shows  NEWS MEDICAL · 2 weeks
Native Hawaiians are at highest risk for pancreatic cancer, according to a USC study that provides a surprising look at disparities surrounding the deadly disease. more
Researchers develop novel imaging test to predict immunotherapy response in kidney cancer  NEWS MEDICAL · 2 weeks
A novel imaging test shows promise for identifying kidney cancer patients most likely to benefit from immunotherapy. more
Research uncovers potential breakthrough in the understanding of tumor dormancy  NEWS MEDICAL · 4 weeks
Scientists at VCU Massey Cancer Center may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to... more
[Focus] Twists and turns to translating 4-1BB cancer immunotherapy  Science Magazine · 7 days
Previous shortcomings of CD137-targeted immunotherapy may be overcome by engineered bispecific agents (Claus et al., this issue). more
Researchers describe how prostate cancer cells develop ability to mimic osteoblasts  NEWS MEDICAL · 3 weeks
Prostate cancer often becomes lethal as it spreads to the bones, and the process behind this deadly feature could potentially be turned against it as a... more
Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer  NEWS MEDICAL · 2 weeks
In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small... more
Key acid-activated protein channel identified  PHYS.ORG · 4 weeks
Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart attack, cancer and inflammation. The researchers believe the discovery... more
Immunotherapy is the most prominent topic in skin cancer research, report reveals  NEWS MEDICAL · 4 weeks
A new report published today highlights the different research areas in the field of skin cancer, showing that immunotherapy is the most prominent topic... more
Potential breakthrough in understanding tumor dormancy  SCIENCE DAILY · 4 weeks
Scientists may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a... more
Immunotherapy drug found safe in treating cancer patients with HIV, study suggests  SCIENCE DAILY · 2 weeks
The results of a new study suggest that patients living with HIV and one of a variety of potentially deadly cancers could be safely... more
Apolipoproten E appears to be new potential druggable target for Alzheimers  NEWS MEDICAL · 6 days
Apolipoproten E is a major genetic risk factor for the development of Alzheimer's disease, yet the protein tends to be understudied as a potential druggable target... more
Alex Trebek's Promising Cancer Update: What Is 'Near Remission'?  LIVE SCIENCE · 3 weeks
Alex Trebek says his tumors have shrunk 50% since he started chemotherapy, but that's no guarantee that the pancreatic cancer will go into full remission. more
Potential new therapeutic target for Alzheimer's disease  SCIENCE DAILY · 6 days
Apolipoproten E (apoeE) is a major genetic risk factor for the development of Alzheimer's disease, yet it tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease. Now a research... more
Study uncovers trigger for cachexia  NEWS MEDICAL · 6 days
Among all major cancers, pancreatic cancer has the highest rate of death - 93 percent of patients die within five years of diagnosis. more
Stroke, cancer and heart disease: Key acid-activated protein channel  SCIENCE DAILY · 4 weeks
Researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart attack, cancer and... more
Novel agent reactivates an immune call by LIF blockade  SCIENCE DAILY · 1 week
Promising new therapy with a dual mechanism of action to eliminate cancer stem cells and activate the immune system now in clinical development. Findings show a reactivation of the anti-cancer... more
Researchers provide insight into unintended consequence of immune checkpoint inhibitors  NEWS MEDICAL · 1 week
Immune checkpoint inhibitors are an emerging type of cancer immunotherapy that uses the immune system to attack cancer cells. more
Promising path towards developing flu treatment using lipid target  SCIENCE DAILY · 4 weeks
A team of scientists has tackled this fundamental question and recently identified a target to 'tone down' the hyper-active immunity to influenza infection. These novel findings have promising clinical implications... more
Research identifies new target that may help develop new treatments for common STD  NEWS MEDICAL · 3 weeks
Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology, Immunology and Parasitology at LSU Health New Orleans School of Medicine, has... more
Characterizing potential therapeutic target to increase heart function after heart attack  NEWS MEDICAL · 4 weeks
A University of Houston College of Pharmacy researcher is characterizing a potential therapeutic target to increase heart function following a heart attack, helping alleviate the symptoms... more
Making structural changes to antibody has potential for reducing cancer tumours  PHYS.ORG · 3 weeks
Guided by "blueprints" produced at the Canadian Light Source (CLS) at the University of Saskatchewan, a group of scientists from academia and industry made structural changes... more
Cause of hardening of the arteries -- and potential treatment -- identified  SCIENCE DAILY · 6 days
A team of scientists have identified the mechanism behind hardening of the arteries, and shown in animal studies that a generic medication normally used... more
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