A multidisciplinary team of researchers have developed an anti-inflammatory drug molecule with a new mechanism of action. By inhibiting a certain protein, the researchers were able to reduce the signals that trigger an inflammation.... SCIENCE DAILY · 3 months
How blood vessels protect the brain during inflammation  SCIENCE DAILY · 1 day
Researchers have discovered how blood vessels protect the brain during inflammation -- a finding that could lead to the development of new treatments for neurodegenerative diseases such as stroke, epilepsy and multiple... more
Mechanism of inflammation initiation through NLRP3 inflammasome activation revealed  NEWS MEDICAL · 4 weeks
Inflammation is the response of our immune system to infection and harmful environmental effects. On one hand, it is beneficial as it defends our body against microbes. On the other... more
Medical News Today: Which herbs help reduce inflammation?  MNT · 3 weeks
Herbs that help reduce inflammation include turmeric and ginger. Green tea is also beneficial. Learn more about the best herbs to help reduce inflammation here. more
Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis  Science Magazine · 2 weeks
Nonresolving inflammation perpetuated by innate leukocytes is involved in the pathogenesis of unstable atherosclerosis. However, the role and regulation of neutrophils related to nonresolving inflammation and atherosclerosis are poorly understood.... more
Inflammation in middle age may indicate increased risk of dementia in later life  NEWS MEDICAL · 1 week
New research indicates that people suffering chronic inflammation during middle age show a greater decline in cognitive function as they get older. more
NSAID impairs immune response in heart failure, worsens heart and kidney damage  SCIENCE DAILY · 2 weeks
Non-steroidal anti-inflammatory drugs, or NSAIDs, are widely known as pain-killers and can relieve pain and inflammation. Researchers found that treatment with the NSAID carprofen... more
Calorie restriction prevents asthma symptoms linked to inflammation in mice  SCIENCE DAILY · 3 weeks
Experimenting with mice, researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet's fat and sugar content. The researchers also say they found that obesity... more
Medical News Today: Inflammation in midlife hastens cognitive decline  MNT · 1 week
Understanding the risk factors of cognitive decline are now more important than ever. A recent study examined the potential role of inflammation. more
Study uncovers new link between inflammation and cancer  NEWS MEDICAL · 4 weeks
Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix of... more
Stopping inflammation from becoming chronic  SCIENCE DAILY · 20 hours
An international research team has developed a highly sensitive cell model to study the complex effects -- and side effects -- of anti-inflammatory drugs, with the ultimate aim of preventing chronic inflammation. more
Combination of PARP inhibitor and immunotherapy results in tumor regression in SCLC mouse models  NEWS MEDICAL · 5 days
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and... more
UMass Amherst scientist explores role of citrus peel in decreasing gut inflammation  NEWS MEDICAL · 2 hours
University of Massachusetts Amherst Professor Hang Xiao, Clydesdale Scholar of Food Science, has received a $1.5 million grant from the National Institutes of Health... more
Study shows how neuroactive steroids inhibit activity of pro-inflammatory proteins  NEWS MEDICAL · 1 week
For the first time, scientists discovered how neuroactive steroids naturally found in the brain and bloodstream inhibit the activity of a specific kind of protein called Toll-like receptors,... more
Interaction between immune factors triggers cancer-promoting chronic inflammation  SCIENCE DAILY · 2 weeks
A research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. more
Research reveals critical immunological axis that triggers cancer-promoting chronic inflammation  NEWS MEDICAL · 2 weeks
A Massachusetts General Hospital research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic,... more
Interaction between bacteria and immune cells protects the intestinal barrier  SCIENCE DAILY · 3 weeks
Conditions such as Crohn's disease or ulcerative colitis, a poor diet, overuse of certain drugs and stress harm the intestinal barrier and cause inflammation. An international study on... more
Elevated levels of key cellular process implicated in intestinal inflammation and IBD  NEWS MEDICAL · 3 days
Elevated levels of the key cellular process of apoptosis have been implicated in intestinal inflammation and inflammatory bowel disease in a new study from... more
When good cells go bad: Regulating the MS-causing properties of Th17 cells  SCIENCE DAILY · 1 week
Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain. Using a mouse model of... more
Newly-Discovered Tarantula Species Has ‘Horn’ on Its Back  SCI-NEWS.COM · 2 weeks
A duo of researchers from South Africa has discovered a remarkable new species of tarantula living in central Angola. The... more
Previously unknown crystalline phase of semi-aqueous calcium carbonate discovered  PHYS.ORG · 4 weeks
A team of researchers from Germany, Israel and the U.S. has discovered a new crystalline phase of semi-aqueous calcium carbonate. In their paper published in the journal Science, the group... more
New species of spider discovered with unusual social skills  PHYS.ORG · 1 week
A researcher at Royal Holloway, University of London, has discovered a new species of spider in Indonesia. more
Novel enzyme discovered in intestinal bacteria  SCIENCE DAILY · 2 weeks
Researchers have discovered a key enzyme for formation of harmful hydrogen sulfide in the human gut by Bilophila bacteria. more
Researchers examine link between OSA and inflammation, organ damage  NEWS MEDICAL · 2 weeks
Voyagers no longer embark in search of the storied Fountain of Youth, but the quest for longevity is still very much alive for researchers. more
[Editors' Choice] Dont overlook the lung  Science Magazine · 3 days
The local lung microbiota provoke inflammation associated with lung adenocarcinoma by activating lung-resident T cells in mice. more
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein  Science Magazine · 1 week
ABCB1, also known as P-glycoprotein, actively extrudes xenobiotic compounds across the plasma membrane of diverse cells, which contributes to cellular drug resistance and interferes with therapeutic drug delivery.... more
Belly-born B cells bathe the brain  Science Magazine · 3 weeks
IgA-expressing antibody secreting cells that are formed in the gut travel to the brain to diminish inflammation during multiple sclerosis exacerbations. more
New therapeutic target for graft-vs-host disease could make bone marrow transplant safer  SCIENCE DAILY · 4 weeks
Graft-versus-host disease (GVHD) is a major complication of bone marrow transplant, a potentially curative treatment for patients with blood-borne cancers such as leukemia and... more
Preventing the production of toxic mitochondrial proteins—a promising treatment target
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