The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.... MIT · 4 months
New CRISPR genome editing system offers a wide range of versatility in human cells  SCIENCE DAILY · 3 weeks
A team has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology... more
New CRISPR genome editing system offers a wide range of versatility in human cells  PHYS.ORG · 3 weeks
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two... more
The evolution of genetic engineering  PHYS.ORG · 1 week
Charles Gersbach, the Rooney Family Associate Professor of Biomedical Engineering at Duke University, leads a lab that is centered on developing and applying genome engineering tools––most notably CRISPR-based technology. CRISPR-Cas is a bacterial defense system that allows bacteria... more
Modified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease  PHYS.ORG · 6 days
City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so... more
CRISPR: More than just for gene editing?  PHYS.ORG · 3 days
The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human gene pool," an ethically... more
Doctors try CRISPR gene editing for cancer, a 1st in the US  ABC NEWS · 1 week
1st attempt in US to use a gene editing tool called CRISPR against cancer seems safe in 3 patients who have had it so... more
New CRISPR genome “prime editing” system  NEWS MEDICAL · 3 weeks
Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and... more
CRISPR Approach To Fighting Cancer Called 'Promising' In 1st Safety Test  NPR · 1 week
Attempts to use the gene-editing tool CRISPR to develop a treatment for cancer seem safe and feasible in the earliest findings from the first three patients.... more
AAV vector integration into CRISPR-induced DNA breaks  PHYS.ORG · 4 weeks
To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses (AAVs) can stably integrate into CRISPR-Cas9-induced... more
Scientists Create New, More Powerful Technique To Edit Genes  NPR · 3 weeks
A new technique, dubbed 'prime editing,' appears to make it even easier to make very precise changes in DNA. It's designed to overcome the limits of the CRISPR gene editing... more
Cytel expands its advanced real-world analytics capabilities with acquisition of MTEK Sciences  NEWS MEDICAL · 6 days
Cytel Inc., the leading provider of innovative analytical software and consulting services to the biopharmaceutical sector, and a portfolio company of New Mountain Capital,... more
A new CRISPR-Cas9 protein to increase precision of gene editing  SCIENCE DAILY · 6 days
Researchers have recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for... more
A new CRISPR-Cas9 protein to increase precision of gene editing  PHYS.ORG · 1 week
A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in... more
CRISPR: More than just for gene editing?  SCIENCE DAILY · 2 days
Researchers have converted the CRISPR 'recognition induced enzymatic signal' to an electrical signal, which was then used to detect the biomarkers for viruses such as HPV or parvo. They hope the end result could... more
CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process  NEWS MEDICAL · 1 week
A team of researchers from City University of Hong Kong and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy... more
Using CRISPR for dose-dependent activation of gene expressions  PHYS.ORG · 1 day
A team of researchers affiliated with several institutions in the U.S. has developed a way to use the CRISPR gene editing technique for dose-dependent activation of gene expressions. In their paper published... more
Improved gene editing technique can successfully cut out undesirable genetic information  NEWS MEDICAL · 6 days
City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more... more
Molecular Scissors Could Help Keep Some Viral Illnesses At Bay  NPR · 7 hours
A new technique uses the CRISPR molecule to snip away at the part of RNA viruses that allows them to spread infection by making copies of themselves. more
Uncovering the principles behind RNA folding  PHYS.ORG · 3 weeks
A Northwestern Engineering research team led by Professor Julius Lucks has uncovered a new understanding of how RNA molecules act as cellular 'biosensors' to monitor and respond to changes in the environment by controlling gene expression.... more
New point-of-care medical device rapidly and accurately detects viruses  NEWS MEDICAL · 2 days
The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human... more
Scientists discover structure of novel RNA-modifying enzyme  NEWS MEDICAL · 1 week
RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure of a novel... more
Boosting host immune defenses to treat tuberculosis  SCIENCE DAILY · 1 day
A study suggests a new approach that might help treat Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis: making people's cells better at killing Mtb by harnessing RNA sensors in our cells, which detect... more
Researchers quantify Cas9-caused off-target mutagenesis in mice  SCIENCE DAILY · 4 weeks
Scientists are finding new ways to improve the use of the CRISPR enzyme Cas9 and reduce the chances of off-target mutations in laboratory mice, according to new results. The findings will help scientists contextualize... more
Better biosensor technology created for stem cells  SCIENCE DAILY · 2 days
A team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. The technology, which features a unique graphene and... more
Better biosensor technology created for stem cells  nanowerk · 2 days
Researchers have created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. The technology, which features a unique graphene and gold-based... more
Uncovering the principles behind RNA folding  SCIENCE DAILY · 3 weeks
Using high-throughput next-generation sequencing technology, a researcher found similarities in the folding tendencies among a family of RNA molecules called riboswitches, which play a pivotal role in gene expression. more
Researchers use AI to identify RNA binding sites on proteins  NEWS MEDICAL · 2 weeks
Researchers have developed an artificial intelligence (AI) tool that can accurately detect which sites on the surface of a protein bind to RNA molecules. more
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