In the world of cancer biology, not all biomarkers are created equal. These molecules that alert doctors that an abnormal process may be underway can appear as an array of aberrant proteins, such as hormones, enzymes or signaling molecules, and vary from patient to patient. Because they are a mixed bag, no one drug exists to attack them.... NEWS MEDICAL · 4 weeks
Discovery: New biomarker for cancer stem cells  SCIENCE DAILY · 4 weeks
Medical researchers have discovered a new biomarker in cancer stem cells that govern cancer survival and spread, and it's raising hope that drug discovery to kill cancer stem cells could follow suit. more
Transitional T cells could help improve cancer immunotherapy  NEWS MEDICAL · 6 days
In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted,... more
Intestinal stem cell genes may link dietary fat and colon cancer  SCIENCE DAILY · 2 weeks
Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a new study.... more
A new pathway to 'reprogram' killer cells  SCIENCE DAILY · 3 weeks
Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers have now discovered that the mechanism by which certain immune cells kill their target cells can also be used... more
UCLA scientists discover link between a protein and human blood stem cell self-renewal  NEWS MEDICAL · 2 weeks
UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study... more
Better biosensor technology created for stem cells  nanowerk · 4 weeks
Researchers have created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. The technology, which features a unique graphene and gold-based... more
Better biosensor technology created for stem cells  SCIENCE DAILY · 4 weeks
A team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. The technology, which features a unique graphene and... more
Important biomarker may help in determining prognosis of brain cancer patients  NEWS MEDICAL · 1 day
A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent... more
How stem cells decide their identity  SCIENCE DAILY · 1 week
Several hundred different cell types of the adult human body are formed during embryonic development, starting from just a few identical stem cells. The differentiation potential of the cells is progressively restricted in the course of... more
Purification scheme allows collection of elusive blood stem cells from zebrafish  NEWS MEDICAL · 1 week
Hematopoietic stem cells are multipotent cells that can develop into every type of blood cell in the body. more
Chip-based optical sensor detects cancer biomarker in urine  PHYS.ORG · 6 days
For the first time, researchers have used a chip-based sensor with an integrated laser to detect very low levels of a cancer protein biomarker in a urine sample. The new technology is... more
Scientists develop a method of targeted drug delivery to cancer cells  NEWS MEDICAL · 1 day
A team of scientists from Peter the Great St.Petersburg Polytechnic University together with their colleagues developed a method of targeted drug delivery to cancer cells. The... more
Transition to exhaustion: Clues for cancer immunotherapy  SCIENCE DAILY · 1 week
Research on immune cells 'exhausted' by chronic viral infection provides clues on how to refine cancer immunotherapy. The Immunity paper defines a transitional stage in between stem-like and truly exhausted cells. more
Researchers discover new pathway to 'reprogram' killer cells  NEWS MEDICAL · 3 weeks
Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by... more
IFN-{gamma}: The T cells license to kill stem cells in the inflamed intestine  Science Magazine · 4 days
IFN- produced by T cells directly induces intestinal stem cell death upon inflammation-induced intestinal injury (see the related Research Article by Takashima... more
Stem cells do not take the day off on national holidays  NEWS MEDICAL · 2 weeks
While most of us are stuffing ourselves with turkey and pumpkin pie at home on Thanksgiving Day, the staff at one Cedars-Sinai laboratory will be on... more
Encouraging normal liver cells to fight cancer  SCIENCE DAILY · 2 weeks
A study discovered that healthy liver tissue surrounding a tumor activates a defense mechanism that restrains tumor growth. Remarkably, the researchers found that hyperactivation of this mechanism above levels normally present in the liver,... more
Stem cells do help restore heart function – but in a different way  NEWS MEDICAL · 2 weeks
A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but... more
T cell-derived interferon-{gamma} programs stem cell death in immune-mediated intestinal damage  Science Magazine · 4 days
Despite the importance of intestinal stem cells (ISCs) for epithelial maintenance, there is limited understanding of how immune-mediated damage affects ISCs and their niche. We found... more
RNA regulation is crucial for embryonic stem cell differentiation  PHYS.ORG · 3 weeks
Embryonic stem cells (ESCs) are distinguished by their dual ability to self-renew and their potential to differentiate, both of which require tight regulatory control. During the differentiation of ESCs, various... more
Brain biomarker predicts compulsive drinking  SCIENCE DAILY · 3 weeks
Although alcohol use is ubiquitous in modern society, only a portion of individuals develop alcohol use disorders or addiction. Yet, scientists have not understood why some individuals are prone to develop drinking problems, while others are not. Now,... more
Genetic features of AML in older patients can predict outcomes after stem cell transplant  NEWS MEDICAL · 2 days
For older patients with acute myeloid leukemia, the prospects for success of a stem cell transplant can often be predicted... more
Tendon stem cells could revolutionize injury recovery  SCIENCE DAILY · 2 weeks
The buildup of scar tissue makes recovery from torn rotator cuffs, jumper's knee, and other tendon injuries a painful, challenging process, often leading to secondary tendon ruptures. New research reveals the existence of tendon... more
New insight into a cancer-shielding protein could guide a new generation of cancer treatments  PHYS.ORG · 3 weeks
In a paper published in Cell Reports, a team of researchers from the Department of Energy's SLAC National Accelerator Laboratory... more
New technique visually depicts how cancer cells grow and spread in colon tissue  SCIENCE DAILY · 1 week
Researchers have observed how stem cell mutations quietly arise and spread throughout a widening field of the colon until they eventually predominate... more
New approach can improve the activity of CAR-T cells against blood and solid cancers  NEWS MEDICAL · 5 days
A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against... more
Research team deciphers how stem cells decide their identity  PHYS.ORG · 1 week
A research team headed by Prof. Dr. Sebastian Arnold and Jelena Tosic from the Faculty of Medicine at the University of Freiburg has now succeeded in deciphering basic molecular control... more
Better biosensor technology created for stem cells  PHYS.ORG · 4 weeks
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. more
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