Scientists report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems. The new method was developed, say the researchers, to deliver an immune system 'uncloaking' device directly to cancer cells.... SCIENCE DAILY · 1 month
Stress during pregnancy can cause lifetime of immune system deficiencies  NEWS MEDICAL · 3 weeks
Mice exposed to stress in the womb and soon after birth can expect a lifetime of immune system deficiencies that hinder the ability to ward off infections and... more
Bacteria-trapping protein may contribute to breast cancer metastasis  NEWS MEDICAL · 1 week
The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular... more
Removing a gene prevents Type 1 diabetes in mice by disguising beta cells  NEWS MEDICAL · 2 days
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack... more
New type of adoptive cell therapy could target prostate and pancreatic cancers in humans  NEWS MEDICAL · 3 weeks
In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted... more
Blocking immune T-cell regulator may help boost tumor killing, study shows  NEWS MEDICAL · 4 weeks
Immune system T-cells are more able to destroy skin cancer cells when a T-cell regulator called SLAMF6 is missing, a new study in eLife shows. more
Too much salt weakens the immune system  SCIENCE DAILY · 3 days
A high-salt diet is not only bad for one's blood pressure, but also for the immune system. Mice fed a high-salt diet were found to suffer from much more severe bacterial infections. Human volunteers... more
The harmful effects of stress during pregnancy can last a lifetime  SCIENCE DAILY · 3 weeks
Mice exposed to stress in the womb and soon after birth can expect a lifetime of immune system deficiencies that hinder the ability to ward off... more
Study reveals breast cancer cells shift their metabolic strategy to metastasize  PHYS.ORG · 3 weeks
New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality... more
Inhibiting energy production in immune T-cells allows some tumors to escape treatment  NEWS MEDICAL · 4 weeks
A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says... more
Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients  NEWS MEDICAL · 6 days
Immunotherapy that involves treating cancer with the body's own immune cells, or those of a matched donor, shows promise in clinical trials... more
Researchers engineer microparticles that show promise against transplant rejection  NEWS MEDICAL · 2 weeks
Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as... more
Immunotherapy using 'young cells' offers promising option against cancer  SCIENCE DAILY · 4 days
A new study suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells -- natural killer (NK) cells --... more
Density of immune cells could accurately predict survival in patients with stage III colon cancer  NEWS MEDICAL · 4 weeks
The density of immune cells, called tumor infiltrating lymphocytes, when combined with analysis of tumor budding may serve... more
How to boost immune response to vaccines in older people  SCIENCE DAILY · 1 day
Identifying interventions that improve vaccine efficacy in older persons is vital to deliver healthy aging for an aging population. Immunologists have identified a route for counteracting the age-related... more
Device could 'hear' disease through structures housing cells  PHYS.ORG · 1 week
Similarly to how a picked lock gives away that someone has broken into a building, the stiffening of a structure surrounding cells in the human body can indicate that cancer is invading... more
Researchers develop a microfluidic chip to help detect prostate cancer  NEWS MEDICAL · 3 weeks
Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with... more
Using 'organs-on-a-chip' to model complicated diseases  SCIENCE DAILY · 1 week
Biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system on a microfluidic chip seeded with human cells. With this 'organs-on-a-chip' model, they could explore the... more
How T cells make sure they have quiet time  PHYS.ORG · 2 weeks
All cells, like all people, need "quiet" time to function properly, and this is particularly true of T cells, one of the immune system's main weapons. They must be ready... more
Scientists create model to measure how cells sense their surroundings  SCIENCE DAILY · 1 day
Our body's ability to detect disease, foreign material, and the location of food sources and toxins is all determined by a cocktail of chemicals that surround our cells,... more
Making sense of cells: Model determines which techniques cells employ to increase sensitivity  PHYS.ORG · 2 days
The body's ability to detect disease, foreign material, and the location of food sources and toxins is all determined by a cocktail... more
Excessive salt intake weakens the immune system  NEWS MEDICAL · 3 days
A high-salt diet is not only bad for one's blood pressure, but also for the immune system. This is the conclusion of a current study under the leadership of the University Hospital Bonn. more
Research reveals rising rates of liver cancer  NEWS MEDICAL · 6 days
New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society. more
Research shows how physical cues drive cell migration, cancer metastasis, and treatment  NEWS MEDICAL · 4 weeks
Cancer cells are a product of their environment. The surrounding cells, extracellular matrix, and other features influence disease progression and spread of cancer cells... more
Selective killing of cancer cells by cluttering their waste disposal system  PHYS.ORG · 2 weeks
A team of researchers from the Center for Soft and Living Matter, within the Institute of Basic Science (IBS, South Korea) and affiliated with Ulsan National... more
Researchers Identify Targets for Effective Immune Responses to SARS-CoV-2 Coronavirus  SCI-NEWS.COM · 2 weeks
Scientists from La Jolla Institute for Immunology, the J. Craig Venter Institute and the University of... more
Scientists find link between immune system and high blood pressure in patients with CKD  NEWS MEDICAL · 4 weeks
Detecting threats, sending out response molecules, and altering gene expression--our immune system works tirelessly day and night to protect us... more
MORE SCIENCE VIDEO
Viral video advises washing fruit and vegetables with soap. Here's why that's a bad idea.
LIVE SCIENCE
A device for the early detection of certain eyesight problems
PHYS.ORG
Financial, economic actions during crisis may be rational, if not ethical
PHYS.ORG
Cellular train track deformities shed light on neurological disease
PHYS.ORG
SLAC structural biologist discovers a strange cavity in key tuberculosis protein
NEWS MEDICAL
Supply chain outlook: Why the situation varies by industry
PHYS.ORG
How diseases rise and fall with the seasons—and what it could mean for coronavirus
Science Magazine
Creating stretchable thermoelectric generators
PHYS.ORG
New 3-D view of methane tracks sources
PHYS.ORG
Chasing lithium ions on the move in a fast-charging battery
PHYS.ORG