A team at the University of Cambridge has shown how, in osteoarthritis patients, the viscous lubricant that ordinarily allows our joints to move smoothly triggers a pain response from nerve cells similar that caused by chilli peppers.... NEWS MEDICAL · 6 days
Joint lubricating fluid plays key role in osteoarthritic pain, study finds  SCIENCE DAILY · 6 days
A team has shown how, in osteoarthritis patients, the viscous lubricant that ordinarily allows our joints to move smoothly triggers a pain response from nerve cells... more
Space station cell study seeks causes of major diseases  PHYS.ORG · 3 weeks
High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The International Space Station experiment is looking... more
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High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The... more
How pieces of live human brain are helping scientists map nerve cells  SCIENCE-NEWS · 2 weeks
Experiments on live nerve cells — donated from patients undergoing brain surgery — may turn up clues about how the human brain works. more
How neuromuscular connections are maintained after nerve lesions  SCIENCE DAILY · 4 weeks
After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers have now shown... more
Multi-tasking protein at the root of neuropathic pain  SCIENCE DAILY · 14 hours
Neuropathic pain is a chronic condition resulting from nerve injury and is characterized by increased pain sensitivity. Although known to be associated with overly excitable neurons in the spinal cord, the mechanisms... more
Researchers find biological system that manages cells' response to opioid drug exposure  NEWS MEDICAL · 2 days
A team at Scripps Research in Florida has discovered a biological system that manages cells' response to opioid drug exposure. The unexpected discovery offers... more
Surgeons report success in reducing opioid prescribing without increasing patients' pain  SCIENCE DAILY · 6 days
A new study shows how one state's surgeons reduced the number of opioids they prescribed to thousands of patients -- without causing patients to feel more... more
Aging nerve cells fail to take out the intracellular "trash"  NEWS MEDICAL · 4 weeks
Researchers at the Perelman School of Medicine at the University of Pennsylvania, have found that with age the neurons or nerve cells fail to perform an activity that... more
[Research Articles] Fluid assessment in dialysis patients by point-of-care magnetic relaxometry  Science Magazine · 4 weeks
Magnetic resonance imaging (MRI) is a powerful diagnostic tool, but its use is restricted to the scanner suite. Here, we demonstrate that a bedside nuclear magnetic... more
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A team has discovered a biological system that manages cells' response to opioid drug exposure. The unexpected discovery offers new ideas for improving the... more
New treatment option shown for heart failure fluid overload  SCIENCE DAILY · 3 weeks
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Researchers identify glial cells as critical players in brain's response to social stress  SCIENCE DAILY · 1 week
Exposure to violence, social conflict, and other stressors increase risk for psychiatric conditions such as depression and post-traumatic stress disorder. A new... more
Key proteins for the repair of nerve fibers identified  SCIENCE DAILY · 2 weeks
Scientists have identified a group of proteins that help to regenerate damaged nerve cells. more
New research provides better way to gauge pain in mice  SCIENCE DAILY · 2 weeks
Neuroscientists have developed a method that can more accurately gauge pain in mice, which could lead researchers to discover new ways to treat pain in human patients. more
Efficient, interconnected, stable: New carbon nanotubes to grow neurons  nanowerk · 3 weeks
By specific chemical modifications, carbon nanotubes were engineered into self-standing innovative materials able to modulate the activity of nerve cells, with the potential of being exploited towards the repair of... more
Scientists identify group of proteins for repair of nerve fibers  NEWS MEDICAL · 2 weeks
Scientists at the German Center for Neurodegenerative Diseases have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal... more
Tiny biodegradable circuits for releasing painkillers inside the body  PHYS.ORG · 2 weeks
Patients fitted with an orthopedic prosthetic commonly experience a period of intense pain after surgery. In an effort to control the pain, surgeons inject painkillers into the tissue during the... more
Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo  Science Magazine · 4 weeks
Alveolar macrophages (AMs) are the first cells to be infected during Mycobacterium tuberculosis (M.tb.) infection. Thus, the AM response to infection is... more
Therapeutic virtual reality can help reduce severe pain in hospitalized patients  NEWS MEDICAL · 5 days
Therapeutic virtual reality can be used to reduce severe pain in hospitalized patients, according to a study published August 14, 2019 in the open-access journal PLOS... more
Small biodegradable implant for releasing local anesthetic inside the body  NEWS MEDICAL · 2 weeks
Patients fitted with an orthopedic prosthetic commonly experience a period of intense pain after surgery. In an effort to control the pain, surgeons inject painkillers into the tissue... more
Predicting post-traumatic osteoarthritis using simplified computational models  NEWS MEDICAL · 16 hours
Knee joint injuries, such as ligament rupture, are common in athletes. As the intact joint ligaments offer a precondition for joint stability, ligament injuries are often surgically reconstructed. However, in many cases these injuries... more
Specialized cutaneous Schwann cells initiate pain sensation  Science Magazine · 5 days
An essential prerequisite for the survival of an organism is the ability to detect and respond to aversive stimuli. Current belief is that noxious stimuli directly activate nociceptive sensory nerve endings in the skin.... more
Alzheimer’s targets brain cells that help people stay awake  SCIENCE-NEWS · 5 days
Nerve cells in the brain that are tied to wakefulness are destroyed in people with Alzheimer’s, a finding that may refocus dementia research. more
Opioid use and misuse 3 months after ED visit for acute pain  SCIENCE DAILY · 2 weeks
Opioid use at the three-month follow-up in emergency department patients discharged with an opioid prescription for acute pain is relatively low and not necessarily... more
Bacteria on tumors influences immune response and survival of patients with pancreatic cancer  SCIENCE DAILY · 2 weeks
Researchers find tumor microbiome influences immune response and patient survival in pancreatic cancer. Study points to fecal transplant as possible treatment. more
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The cannabis plant produces pain-relieving molecules that are 30x more effective than aspirin. Researchers are now working on a plant-based pain killer. more
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