An investigational drug for the treatment of sickle cell disease is showing early promise in clinical trials for impacting biomarkers of the disease in patients, reported UConn School of Medicine researchers at the European Hematology Association Congress in Amsterdam this week.... NEWS MEDICAL · 1 month
Pitt/UPMC researchers to lead large clinical trial to test red cell exchange in sickle cell disease  NEWS MEDICAL · 2 weeks
Medical advances have dramatically increased the life expectancy of patients with sickle cell disease, but as... more
Stem cell stimulation shows promise as potential stroke treatment  NEWS MEDICAL · 3 weeks
Stem cell stimulation shows promise as a potential noninvasive stroke treatment, according to research in mice published in JNeurosci. more
Larger drug trials that intervene earlier needed for Alzheimer's disease  SCIENCE DAILY · 2 weeks
There are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients' cognitive function did not improve. Would... more
Chronic kidney disease patients are excluded from clinical trials  NEWS MEDICAL · 2 weeks
Kidney diseases affect 850 million people worldwide, a figure twice as high as that of diabetes. Yet patients with chronic kidney disease are still being excluded from clinical trials. more
Study highlights the need for larger Alzheimer's drug trials that intervene much earlier  NEWS MEDICAL · 2 weeks
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New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy. PARP... more
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A drug belonging to a new generation of acute migraine headache treatments was found to eliminate pain and reduce bothersome symptoms for people with... more
Stem cell stimulation improves stroke recovery  SCIENCE DAILY · 3 weeks
Stem cell stimulation shows promise as a potential noninvasive stroke treatment, according to new research. If extended to humans, this technique could greatly improve patients' quality of life. more
Single-cell encapsulation technology can protect transplanted MSCs from immune attack  NEWS MEDICAL · 5 days
Bone marrow transplants of hematopoietic stem cells have become standard treatment for a host of conditions including cancers of the blood and lymphatic systems, sickle cell anemia, inherited... more
Study shows promise for a drug to extend life of patients with ovarian cancer  NEWS MEDICAL · 3 weeks
Women with ovarian cancer who have undergone four or more rounds of chemotherapy typically haven't had much hope that another... more
New drug provides hope for patients with Duchenne muscular dystrophy  NEWS MEDICAL · 2 weeks
The results from three clinical trials have shown that a new drug can successfully delay the progression of Duchenne muscular dystrophy. more
Computer-generated flu vaccine enters clinical trials in the US  NEWS MEDICAL · 2 weeks
A seasonal flu vaccine that has been developed entirely by artificial intelligence on a computer is set to be tested in clinical trials in the US. more
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Researchers examined how artificial intelligence (AI) could affect drug development in the coming decade. more
Copper compound with potential as therapy for ALS shows further promise  NEWS MEDICAL · 3 weeks
A compound with potential as a treatment for ALS has gained further promise in a new study that showed it improved the condition of mice whose... more
More effective flu vaccine begins clinical trials across the U.S.  NEWS MEDICAL · 3 weeks
A more effective seasonal flu vaccine is about to be tested in clinical trials across the US. more
Exclusive: FDA enforcement actions plummet under Trump  Science Magazine · 3 weeks
FDA actions that safeguard clinical trials, food and drug safety in steep decline, Science investigation reveals more
Duchenne muscular dystrophy: New analysis shows drug slows down respiratory decline  SCIENCE DAILY · 2 weeks
Duchenne muscular dystrophy occurs in boys and is characterized by progressive muscle degeneration and weakness leading to a decline in respiratory function. Strategies to arrest this... more
Antioxidant precursor molecule could improve dopamine levels in Parkinson's patients  NEWS MEDICAL · 5 days
N-acetylcysteine (NAC) is a naturally occurring molecule that replenishes one of the body's antioxidants and now shows potential benefit as part of a standard course of treatment for... more
New therapy shows promise in preventing brain damage after traumatic brain injury  NEWS MEDICAL · 5 days
Nearly three million people in the United States experience traumatic brain injury (TBI) every year, and there are no pre or post-TBI treatment options... more
Accessing neuroinflammation sites: Monocyte/neutrophil-mediated drug delivery for cerebral ischemia  Science Magazine · 2 weeks
Cerebral ischemia (CI) results from inadequate blood flow to the brain. The difficulty of delivering therapeutic molecules to lesions resulting from CI hinders the effective treatment of this disease. The... more
Keck School of Medicine of USC to recruit patients typically underrepresented in clinical trials  NEWS MEDICAL · 5 days
A highly competitive $4.5 million grant from the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute will... more
Unmasking mutant cancer cells  MIT · 4 days
A new dosing regimen for an old cancer drug shows new promise as an immunotherapy. more
Dundee and Bukwang Pharm announce partnership to develop new drug for Parkinson's  NEWS MEDICAL · 3 weeks
The University of Dundee's Drug Discovery Unit has announced a multi-million-pound partnership with Korea-based Bukwang Pharmaceutical Company in a bid to develop a new... more
New class of cancer-killing agents shows promise in destroying cancer stem cells  NEWS MEDICAL · 2 weeks
Scientists at The University of Toledo investigating improvements to a commonly used chemotherapy drug have discovered an entirely new class of cancer-killing agents that... more
New Markers For Alzheimer's Disease Could Aid Diagnosis And Speed Up Drug Development  NPR · 3 weeks
Researchers are using brain scans, blood and spinal fluid to detect early signs of Alzheimer's disease. These "biomarkers" may also offer a... more
Vast majority of dietary supplements don't improve heart health or put off death, study finds  SCIENCE DAILY · 5 days
In a massive new analysis of findings from 277 clinical trials using 24 different interventions, researchers say they... more
FDA grants accelerated approval to new treatment for refractory multiple myeloma  NEWS MEDICAL · 3 weeks
Today, the U.S. Food and Drug Administration granted accelerated approval to Xpovio (selinexor) tablets in combination with the corticosteroid dexamethasone for the treatment of adult patients... more
The way sickle cells form may be key to stopping them  SCIENCE DAILY · 3 weeks
Chemists are reporting a new finding on how sickle cells are formed, which may lead not only to stopping their formation, but to new avenues for... more
Patients with HIV DNA in cerebrospinal fluid have high risk of experiencing cognitive deficits  NEWS MEDICAL · 6 days
Investigators from the AIDS Clinical Trials Group, the world's largest and longest-established HIV research network, today announced that the Journal... more
Shingles vaccine safely prevents outbreaks among stem cell transplant patients  SCIENCE DAILY · 2 weeks
A newer form of shingles vaccine reduced outbreaks of the painful rash among patients who were transplanted with their own stem cells, according to a new study. The... more
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