Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.... PHYS.ORG · 1 week
How host-cell enzymes combat the coronavirus  SCIENCE DAILY · 1 week
Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a new study. more
Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds  NEWS MEDICAL · 4 days
Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal... more
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Hydrogenases are enzymes that catalyze hydrogen activation. There are three types of hydrogenases in nature, all containing iron and some of them nickel. But in synthetic chemistry there is a whole host... more
Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases  Science Magazine · 2 days
Enzymes with a protein kinase fold transfer phosphate from adenosine 5'-triphosphate (ATP) to substrates in a process known as phosphorylation. Here, we show that the Legionella... more
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Viruses are masterful invaders. They cannibalize host cells by injecting their genetic material, often making thousands of copies of themselves... more
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Site-selective enzymatic C-H amidation for synthesis of diverse lactams  Science Magazine · 2 weeks
A major challenge in carbon-hydrogen (C-H) bond functionalization is to have the catalyst control precisely where a reaction takes place. In this study, we report engineered cytochrome P450 enzymes that... more
Study shows cell's cytoskeleton does more than hold up a cell, it transfers energy  PHYS.ORG · 2 weeks
Dysfunctions and malformations in the scaffold of a cell are thought to contribute to heart muscle weakness, neurodegenerative disease and... more
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Combat personnel with brain injuries pinpoints abnormal brain waves  SCIENCE DAILY · 2 weeks
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New research may be used to treat cancer, heal combat wounds  PHYS.ORG · 3 weeks
Army research is the first to develop computational models using a microbiology procedure that may be used to improve novel cancer treatments and treat combat wounds. more
TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer  Science Magazine · 4 weeks
TET enzymes are dioxygenases that promote DNA demethylation by oxidizing the methyl group of 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Here, we... more
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New single-cell omics technology allows scientists to analyse cell development in ways that were not previously possible. Researchers can now identify never-before-seen patterns and phenomena across large quantities of cells—receiving information about genomes, gene... more
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Democratic presidential candidate Elizabeth Warren has unveiled a new version of her plan to combat America's opioid epidemic, proposing to spend $100 billion over 10 years on battling the consequences... more
How molecular escorts help prevent cancer  SCIENCE DAILY · 4 days
The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research shows that this inborn cancer... more
Disease-causing nibbling amoeba hides by displaying proteins from host cells  SCIENCE DAILY · 4 weeks
A parasitic amoeba that causes severe gut disease in humans protects itself from attack by biting off pieces of host cells and putting their proteins on its own... more
Warren releases $100 billion plan to combat opioid epidemic  ABC NEWS · 2 weeks
Democratic presidential candidate Elizabeth Warren has unveiled a new version of her plan to combat America's opioid epidemic, proposing to spend $100 billion over 10 years on battling the consequences... more
Disease-causing nibbling amoeba hides by displaying proteins from host cells  PHYS.ORG · 4 weeks
A parasitic amoeba that causes severe gut disease in humans protects itself from attack by biting off pieces of host cells and putting their proteins on its own... more
Researchers debut first comprehensive view of human cell division  PHYS.ORG · 3 days
The Allen Institute today released the Integrated Mitotic Stem Cell, a data-driven model and visualization tool that captures—for the first time—a holistic view of human cell division. By enabling a... more
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