Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.... PHYS.ORG · 3 months
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Scientists of South Ural State University are studying enzymes that can break down stress hormones. They are also finding a way to regulate the activity of these enzymes.... more
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Host cell metabolism can be modulated by viral infection, affecting viral survival or clearance. The cellular metabolism rewiring mediated by N6-methyladenosine (m6A) modification in virus-host interaction remains largely unknown. Here... more
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Researchers at the University of Dundee have made an important discovery about two enzymes that have evolved over billions of years to... more
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The microbiota influences obesity, yet organisms that protect from disease remain unknown. During studies interrogating host-microbiota interactions, we observed the development of age-associated metabolic syndrome (MetS). Expansion of Desulfovibrio and... more
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To a large extent, DNA methylation, which regulates vital cell functions, is still a big mystery to the scientific world. Now,, scientists have developed a method to quickly couple methylation enzymes to their respective methylation pattern.... more
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Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We... more
Rhizobial tRNA-derived small RNAs are signal molecules regulating plant nodulation  Science Magazine · 1 month
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Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss  Science Magazine · 3 days
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Expression of M gene segment of influenza A virus determines host range  SCIENCE DAILY · 1 week
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Stem cell differentiation trajectories in Hydra resolved at single-cell resolution  Science Magazine · 1 month
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Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes  Science Magazine · 3 days
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