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Using sponges to wipe out cancer  SCIENCE DAILY · 7 hours
Manzamine A, a natural product derived from certain groups of sponges, can block the growth of cervical cancer cells, report researchers. Manzamine A targets a protein that is highly expressed in many cancers, including cervical cancer,... more
New temperature sensing mechanism in plants  SCIENCE DAILY · 1 day
Cell biologists reveal the phytochrome B molecule has unexpected dynamics activated by temperature, and behaves differently depending on the temperature and type of light. As climate change warms the world, crop growth patterns and flowering times... more
International Panel Releases Guidelines on Management of ICU Patients with COVID-19  SCI-NEWS.COM · 1 day
The Surviving Sepsis Campaign COVID-19 panel, which includes 36 experts from 12 countries, has... more
Treating COVID-19 in a patient with multiple myeloma  SCIENCE DAILY · 1 day
A case study of a patient in Wuhan, China, suggests that the immunosuppressant tocilizumab may be an effective COVID-19 treatment for very ill patients who also have multiple myeloma and other blood... more
To divide or not to divide? The mother cell may decide  SCIENCE DAILY · 1 day
Researchers have found that it's actually the mother cell that determines if its daughter cells will divide. The finding sheds new light on the cell cycle... more
Starving pancreatic cancer of cysteine may kill tumor cells  SCIENCE DAILY · 2 days
In a new study of mice, researchers have found that an experimental drug that breaks down the amino acid cysteine slows pancreatic tumor growth by causing ferroptosis, an unusual form... more
UPV leads development of new mechanical ventilator for patients with COVID-19  NEWS MEDICAL · 2 days
The Universitat Politècnica de València has led the development of a new mechanical ventilator, ready for a quick industrial production. It would provide hospitals with these... more
Drugs considered for COVID-19 can increase risk for dangerous arrhythmias  NEWS MEDICAL · 2 days
As some consider treating coronavirus patients with a combination of the malaria drug hydroxychloroquine and the antibiotic azithromycin, cardiologists are advising caution because both medications can increase the... more
Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis  NEWS MEDICAL · 2 days
A new study from Columbia University Irving Medical Center and the Herbert Irving Comprehensive Cancer Center suggests a compound in development for a rare kidney stone disease may... more
Designing face shields to protect healthcare workers treating COVID-19 patients  NEWS MEDICAL · 2 days
The COVID-19 pandemic has created an unprecedented need to provide personal protective equipment for hospital staff. more
New study overturns ‘snapshot’ model of cell cycle accepted since 1974  NEWS MEDICAL · 2 days
Cells have a big decision: Should they replicate or sleep? Healthy cells can go either way. Cancer cells' replication switches are stuck in the 'on' position. more
Potential of using psychedelic drugs in psychiatry  SCIENCE DAILY · 2 days
Before they were banned about a half century ago, psychedelic drugs like LSD and psilocybin showed promise for treating conditions including alcoholism and some psychiatric disorders. Researchers say it's time for regulators, scientists, and... more
Cysteine depletion induces pancreatic tumor ferroptosis in mice  Science Magazine · 2 days
Ferroptosis is a form of cell death that results from the catastrophic accumulation of lipid reactive oxygen species (ROS). Oncogenic signaling elevates lipid ROS production in many tumor types and is counteracted... more
Structural basis for allosteric PARP-1 retention on DNA breaks  Science Magazine · 2 days
The success of poly(ADP-ribose) polymerase–1 (PARP-1) inhibitors (PARPi) to treat cancer relates to their ability to trap PARP-1 at the site of a DNA break. Although different forms of PARPi... more
A 3-D-printed brain could make it easier to find cancer treatments  PHYS.ORG · 3 days
Glioblastoma is the deadliest form of brain tumor—less than 10 percent of people who are diagnosed with it will survive more than five years. more
Breast density, microcalcifications, and masses are heritable features, analysis reveals  NEWS MEDICAL · 3 days
An analysis of a large Swedish cohort revealed that breast density, microcalcifications, and masses are heritable features, and that breast density and microcalcifications were positively associated with a... more
Majority of patients with mantle cell lymphoma may benefit from CAR T-cell therapy KTE-X19  NEWS MEDICAL · 3 days
A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with... more
Significant global investment in treating children with cancer could save 11 million lives  NEWS MEDICAL · 3 days
A significant, sustained, global investment in treating children with cancer could save 11 million lives and yield a triple return on investment,... more
Immunotherapy may benefit mCRPC patients with specific markers of immune activation  NEWS MEDICAL · 3 days
Although metastatic castration-resistant prostate cancer typically has limited response to immunotherapy, a subset of patients with pretreatment evidence of active T-cell responses in their tumors experienced... more
New guidelines for health-care workers treating ICU patients with COVID-19  NEWS MEDICAL · 3 days
An international team including McMaster University researchers has come together to issue guidelines for health-care workers treating intensive care unit patients with COVID-19. more
Understanding hereditary medulloblastomas in children  NEWS MEDICAL · 3 days
This is a combined press release between EMBL, the Hopp Children's Cancer Center Heidelberg and the German Cancer Consortium. more
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