A targeted therapy drug used for breast and kidney cancers may also extend progression-free survival for patients with advanced head and neck cancer who are at high risk for recurrence after standard treatment.... NEWS MEDICAL · 1 month
Combination of radiation and immunotherapy shows promise for advanced head and neck cancers  NEWS MEDICAL · 1 month
A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity... more
Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers  NEWS MEDICAL · 1 month
A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide... more
YAP signal pathway plays a vital role in the onset of head-and-neck cancer  NEWS MEDICAL · 4 days
Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal... more
Study improvements in survival rates for all cancers in young adults  NEWS MEDICAL · 4 weeks
A new study in the Journal of the National Cancer Institute, published by Oxford University Press, finds improvements in five-year survival rates for all cancers in... more
A previously unknown mechanism could be new therapeutic target for cancer immunotherapy  NEWS MEDICAL · 3 weeks
Researchers at UC have discovered a previously unknown mechanism that could explain the reason behind decreased immune function in cancer patients and could be... more
Study finds improvements in survival rates for all cancers in young adults  NEWS MEDICAL · 4 weeks
A new study in the Journal of the National Cancer Institute, published by Oxford University Press, finds improvements in five-year survival rates for all... more
Immunotherapy treatment shows promise for some patients with advanced rare cancers  NEWS MEDICAL · 1 week
A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of... more
[Research Articles] Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors  Science Magazine · 2 weeks
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer that does not respond to endocrine therapy or human epidermal growth factor receptor... more
Study provides new evidence about optimal way to treat BRCA carriers with breast cancer  NEWS MEDICAL · 3 weeks
Commonly known as the breast cancer genes, the BRCA gene family plays a role in repairing damaged DNA. Inherited mutations... more
Lung cancer medication may have benefits for patients with metastatic brain cancers  NEWS MEDICAL · 3 days
A medication commonly used to treat non-small cell lung cancer that has spread, or metastasized, may have benefits for patients with metastatic brain cancers,... more
YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma  Science Magazine · 1 week
Head-and-neck squamous cell carcinoma (HNSCC) is the sixth most common group of cancers in the world, and patients... more
Study: Five-year survival rate for adolescents and young adults with cancer has improved  NEWS MEDICAL · 4 weeks
The five-year survival rate for adolescents and young adults with cancer has significantly improved from 1975 to 2005 in the United States... more
[Research Articles] Strong vaccine responses during chemotherapy are associated with prolonged cancer survival  Science Magazine · 1 week
Therapeutic cancer vaccines have effectively induced durable regressions of premalignant oncogenic human papilloma virus type 16 (HPV16)–induced anogenital lesions. However, the treatment... more
[Research Articles] Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy  Science Magazine · 2 weeks
PD-L1/PD-1 blocking antibodies have demonstrated therapeutic efficacy across a range of human cancers. Extending this benefit to a greater number of patients, however, will require a... more
Combined biopsy more likely to detect aggressive prostate cancers than standard biopsy alone  NEWS MEDICAL · 3 weeks
Using a combination of magnetic resonance imaging (MRI) to target and sample suspicious prostate tissue along with a standard prostate biopsy is... more
Postmenopausal breast cancer and the benefit of genetic testing  NEWS MEDICAL · 3 weeks
A new study shows that genetic mutations could be detected in one in 40 women diagnosed with breast cancer before the age of 65 years. The study from Stanford researchers,... more
Study reveals breast cancer cells shift their metabolic strategy to metastasize  PHYS.ORG · 3 weeks
New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality... more
[Research Articles] A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection  Science Magazine · 1 week
Accurate and noninvasive monitoring of renal allograft posttransplant is essential for early detection of acute rejection (AR) and... more
Unmasking a hidden killer: Successfully detecting cancer in blood of patients undergoing treatment  PHYS.ORG · 1 week
Pancreatic cancer is one of the most lethal cancers, but difficult to diagnose: few sufferers have symptoms until the cancer has become... more
Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo  NEWS MEDICAL · 1 week
In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions,... more
New discovery could lead to better strategies for preventing breast cancer metastasis  NEWS MEDICAL · 3 weeks
New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively... more
Levels of sBTLA proteins may be a marker of overall survival in patients with HCC  NEWS MEDICAL · 3 weeks
In the 2020 February 25 issue of Scientific Reports, a research group from the Department of Hepatology in... more
[Editors' Choice] Boosting immune responses against early breast cancer  Science Magazine · 1 week
Pembrolizumab combined with neoadjuvant chemotherapy improves therapeutic responses in patients with early triple-negative breast cancer. more
NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists  Science Magazine · 1 week
Several immunotherapy approaches that mobilize CD8+ T cell responses stimulate tumor rejection, and some, such as checkpoint blockade, have been... more
Study shows disparities in guideline-concordant treatment for NSCLC patients  NEWS MEDICAL · 3 days
Lung cancer is the leading cause of cancer-associated deaths in the United States. Non-small cell lung cancer (NSCLC), a group of lung cancers named for the kinds of cells found... more
New tool may benefit frail patients in multi-hospital health systems  NEWS MEDICAL · 4 weeks
Frail patients in private-sector, multi-hospital health systems may benefit from a tool that can quickly predict their risk for poor outcomes following surgery, including postoperative mortality, readmission and... more
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