Early immune-related molecular changes in airway tissue could potentially predict invasive lung cancer and serve as prevention targets, new study suggests. more

Researchers from the Rudolf Virchow Center of the University of Würzburg (JMU) have solved the structures of the cancer-promoting enzymes USP25 and USP28, and identified significant differences in their activities. Both enzymes... more

While non-small cell lung cancer is the more common form of lung cancer and attracts the lion's share of the research funding,... more

University of Texas at Dallas scientists have demonstrated that the growth rate of the majority of lung cancer cells relates directly to the availability of a crucial oxygen-metabolizing molecule. more

New research in mice and human cells suggests that capsaicin, the compound that gives red peppers its spicy flavor, may slow lung cancer progression. more

Single-cell sequencing reveals 25 subpopulations of myeloid cells, a poorly understood family of immune cells, in lung cancer tumors. Many subpopulations are similar across... more

Cancer cells demand enormous amounts of molecular 'food' to survive and grow, and a new study may have identified a new approach to starve the cells of one of the most common... more

Researchers at The University of Texas MD Anderson Cancer Center have discovered that triple negative breast cancer cells can develop resistance to... more

Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells. more

Researchers have solved the structures of the cancer-promoting enzymes USP25 and USP28, and identified significant differences in their activities. Both enzymes promote the growth of various tumors. The results could benefit towards... more

study from the University of Southern California, Keck School of Medicine, sought to examine possible health disparities in the treatment of lung cancer within the Asian community in... more

Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy.... more

Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy.... more

Excess weight before age 50 may be more strongly associated with pancreatic cancer mortality risk than excess weight... more

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those... more

An international team of scientists employed an array of next-generation sequencing and gene-editing tools, such as CRISPR, to map the molecular dependencies - and thus vulnerabilities -- of pancreatic cancer... more

Drinking coffee has been linked to a slew of health benefits, but a new study suggests coffee intake may be linked to an increased... more

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in... more

A deep-learning model developed using serial image scans of tumors from patients with non-small cell lung cancer (NSCLC) predicted treatment response and survival outcomes better than standard clinical parameters. more

Lip cancer is a type of head and neck cancer that often starts with a lump on the lip that does not heal. Common risk factors for lip cancer include... more

Australian researchers have discovered a new molecular pathway in the brain that triggers more weight gain in times of stress. more

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment. more

In recent years, it's become clear that RNA-binding proteins play a major role in cancer growth. These proteins, active in all cells but especially so in cancer cells, bind to RNA molecules... more

Unfortunately, cancer isn't simply a single disease, and some types, like pancreas, brain or liver tumours, are still difficult to treat with chemotherapy, radiation therapy or surgery, leading to low survival rates for patients. Thankfully, new... more

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients... more

A Lancaster PhD student is investigating the effects on older people's health of chronic exposure to low level carbon monoxide. more

Researchers have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They've found that aggressive tumors are often dominated by... more

Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death... more

Inflammation is a balanced physiological response—the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To... more

Levels of violence, incarceration and lead exposure in a neighborhood can predict a low-income child’s future earnings and outcome, a study suggests. more