Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time. Researchers sequenced the genomes of the same cancer across different species to pinpoint key cancer genes. The results give insights into how cancer evolves across the tree of life and could guide the development of new therapies.... SCIENCE DAILY · 6 days
Comparison of cancer genes across species helps prioritize targets for new cancer therapies  NEWS MEDICAL · 5 days
Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for... more
Mapping esophageal cancer genes leads to new drug targets  SCIENCE DAILY · 2 weeks
Mutations that cause esophageal adenocarcinoma (OAC) have been mapped in unprecedented detail -- unveiling that more than half could be targeted by drugs currently in trials for other cancer types. more
Cancer has a biological clock and this drug may keep it from ticking  SCIENCE DAILY · 4 weeks
Scientists find and test a promising drug that stops cancer by interfering with the cancer cells' metabolism and other circadian-related functions. more
World Cancer Day 2019 highlights the need for urgent action to improve early cancer detection  NEWS MEDICAL · 2 weeks
World Cancer Day 2019 highlights the need for urgent action to increase early stage cancer detection, screening, and... more
Drug treating breast cancer may be effective in treating lung and ovarian cancer  NEWS MEDICAL · 2 weeks
Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used... more
Combination treatment, diabetes drug and immunotherapy, may help to fight breast cancer  SCIENCE DAILY · 2 weeks
Researchers in Finland have discovered a drug combination that collaborates with the cancer cells' own MYC oncoprotein, which in large quantities causes self-destruction of... more
Drug-induced cellular membrane complexes induce cancer cell death  PHYS.ORG · 5 days
Old molecules and new complexes: researchers at Hollings Cancer Center at the Medical University of South Carolina (MUSC) have discovered cell membrane complexes called ceramidosomes that may be a new target for... more
'Trojan horse' drug shows promise for untreatable cancers  NEWS MEDICAL · 1 week
A new cancer drug that uses a ‘Trojan horse’ approach to destroy cancer cells from within has shown promising results for patients with untreatable cancers. more
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Scientists have issued a warning to cancer drug developers by revealing that p53, a protein that usually suppresses tumors, can also promote cancer. more
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The first study in the world to take a detailed look at scar tissue in human pancreatic cancer has revealed a range of different scar tissue types that... more
Study highlights need for reliable therapeutic targets for prevention, treatment of cardiovascular diseases  NEWS MEDICAL · 4 weeks
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Drug compound could be next-generation treatment for aggressive form of leukemia  SCIENCE DAILY · 3 weeks
Researchers are developing a series of drug compounds that have shown promise in treating acute myeloid leukemia, an aggressive blood cancer that is one of the... more
Drug cocktail may help combat breast cancer  NEWS MEDICAL · 2 weeks
MYC, a gene with high cancer-initiating potential, is overexpressed in over 40% of breast cancers. While MYC programs breast cancer cells to build more macromolecules (anabolic metabolism) it also creates a metabolic vulnerability by... more
Drug combinations could become first-line treatment for metastatic kidney cancer  NEWS MEDICAL · 8 hours
A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an... more
Physicians more likely to prescribe drugs of manufacturers who paid them money  NEWS MEDICAL · 2 weeks
In a study published in The Oncologist, physicians treating certain cancers who consistently received payments from a cancer drug's manufacturer were more likely to... more
New genes associated with the leading cause of blindness  SCIENCE DAILY · 4 weeks
A new study identifies genes associated with Age-related Macular Degeneration (AMD) that could represent new targets for future drug development. more
Revealing the path of a metallodrug in a breast cancer cell  PHYS.ORG · 2 weeks
Some types of cancer cannot be treated with classical chemotherapy. Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron,... more
An engineered virus selectively targets and kills cancer cells  NEWS MEDICAL · 3 weeks
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers. more
Trojan Horse approach to cancer therapy shows promise  NEWS MEDICAL · 7 days
A new form of cancer fighting drug has been developed using the principles of the “Trojan Horse”. more
Shared genetic marker offers new promise in targeting specific ovarian and lung cancers  SCIENCE DAILY · 2 weeks
Two new articles offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two... more
Brazil-endemic plant genus Mcvaughia highlights diversity in a unique biome  SCIENCE DAILY · 7 days
A new species of the Brazil-endemic small genus Mcvaughia described as part of a extended revision of this unique group. Mcvaughia is a genus of the plant family... more
Trump highlights health agenda with vow to lower ‘unfair’ drug prices  NEWS MEDICAL · 2 weeks
It was not the centerpiece, but health was a persistent theme in President Donald Trump's State of the Union address at the Capitol on Tuesday night. more
Researchers unravel path of metallodrug in a breast cancer cell  NEWS MEDICAL · 2 weeks
Some types of cancer cannot be treated with classical chemotherapy. Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron, are working... more
OCTN: A transporter with relevance to human pathophysiology, drug discovery and diagnostics  PHYS.ORG · 3 weeks
In the February 2019 issue of SLAS Discovery, a review by researchers from the University of Calabria (Italy) explores OCTNs, a small but intriguing... more
Norwegian scientists discover new small molecule drug to treat prostate cancer  NEWS MEDICAL · 4 weeks
Professor Fahri Saatcioglu at University of Oslo's Department of Biosciences (IBV) heads a research group investigating how androgens - male sex hormones - affect the risk... more
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A new study of Tasmanian devils has revealed that a transmissible cancer which has devastated devil populations in recent years in unlikely to cause extinction of the iconic species. more
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