Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time. Researchers sequenced the genomes of the same cancer across different species to pinpoint key cancer genes. The results give insights into how cancer evolves across the tree of life and could guide the development of new therapies.... SCIENCE DAILY · 2 months
Using a promiscuous inhibitor to uncover cancer drug targets  PHYS.ORG · 3 weeks
Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells. more
Scientists use a promiscuous inhibitor to uncover cancer drug targets  NEWS MEDICAL · 3 weeks
Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer... more
Using a promiscuous inhibitor to uncover cancer drug targets  SCIENCE DAILY · 3 weeks
Scientists have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells. more
Hundreds of new anti-cancer drug targets identified using CRISPR  NEWS MEDICAL · 2 weeks
A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells. more
Scientists 'reverse engineer' brain cancer cells to find new targets for treatment  SCIENCE DAILY · 1 week
Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death... more
Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer  NEWS MEDICAL · 4 weeks
A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led... more
How immune cells help tumors escape body's defenses  SCIENCE DAILY · 3 weeks
New findings reveal how immune cells turn off killer T cells, pointing to new drug targets that can improve the success of cancer immunotherapy. more
Scanning for cancer treatment  SCIENCE DAILY · 1 week
11,000 people are predicted to die from acute myeloid leukemia (AML) in 2019. Recently, drug developers designed a new treatment to target the cancer's mutated genes. But, these drugs don't always work. Now, in a new study, researchers investigate both... more
Cancer prevention drug also disables H. pylori bacterium  SCIENCE DAILY · 4 weeks
A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, researchers have discovered. more
Tumor-associated immune cells hinder frontline chemotherapy drug in pancreatic cancer  SCIENCE DAILY · 4 weeks
A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action. more
Medical News Today: This drug failed to treat cancer, but it could improve dementia  MNT · 4 weeks
Scientists have found that an experimental drug that failed against cancer may treat dementia instead. However, can they test it... more
Medical News Today: Cancer: Scientists find 129 'jumping genes' that drive tumor growth  MNT · 2 weeks
A study of thousands of tumors from 15 cancer types highlights the widespread role of jumping genes as cancer promoters and identifies... more
Cancer prevention drug also reduces virulence of H. pylori bacterium  NEWS MEDICAL · 4 weeks
A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach... more
Scientists target metastasis in the battle against cancer  NEWS MEDICAL · 4 weeks
An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future. more
This drug failed to treat cancer, but it could improve dementia  MNT · 4 weeks
Scientists have found that an experimental drug that failed against cancer may treat dementia instead. However, can they test it in clinical trials? more
New study targets Achilles' heel of pancreatic cancer, with promising results  SCIENCE DAILY · 1 week
Advanced pancreatic cancer is often symptomless, leading to late diagnosis only after metastases have spread throughout the body. Now, researchers have uncovered the role of a... more
Loss of a DNA repair system creates a unique vulnerability in many cancer types  SCIENCE DAILY · 2 weeks
Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in... more
Drug takes aim at cancer metastasis  SCIENCE DAILY · 3 weeks
Many cancers are relatively harmless at their site of origin, and it is only when they metastasize to sites like the brain, bones, lungs, and liver that they become especially dangerous. And so, in addition to... more
New analysis establishes global microbial signatures for colorectal cancer  NEWS MEDICAL · 3 weeks
Cancers have long been known to arise due to environmental exposures such as unhealthy diet or smoking. Lately, the microbes living in and on our body have entered the stage... more
Cancer-killing combination therapies unveiled with new drug-screening tool  SCIENCE DAILY · 2 weeks
Scientists have designed a large-scale screen that efficiently identifies drugs that are potent cancer-killers when combined, but only weakly effective when used alone. more
Anti-evolvability drugs could slow antibiotic resistance in bacteria  SCIENCE DAILY · 3 weeks
Researchers found that one mechanism by which antibiotics induce drug-resistance mutations in bacteria is by triggering the generation of high levels of toxic molecules called reactive oxygen species (ROS). Additionally, treatment with... more
Helping infants survive brain cancer  SCIENCE DAILY · 4 weeks
Choroid plexus carcinoma (CPC) is a particularly challenging type of brain cancer: The tumor most commonly arises in infants under the age of one. Progress in developing effective therapies has been hindered by the lack of models that... more
New hope for treating childhood brain cancer  SCIENCE DAILY · 3 weeks
Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting... more
Glowing tumors show scientists where cancer drugs are working  SCIENCE DAILY · 4 weeks
Experimenting with mice, researchers report they have successfully used positron emission tomography (PET) scans to calculate in real time how much of an immunotherapy drug reaches a tumor and what... more
Light and peptides: New method diversifies natural building blocks of life  PHYS.ORG · 7 days
Discovering new biological targets is a critical part of our ongoing battle against diseases. Over the years, scientists have made impressive progress towards the understanding of... more
Cancer drug shortages result in almost no treatment changes  SCIENCE DAILY · 2 weeks
For the vast majority of cancer drugs experiencing shortages over a seven-year period, a new research study found no statistically significant effect of shortages on chemotherapy treatment. more
New computational model of human kinase may provide insights for cancer drug development  NEWS MEDICAL · 3 weeks
Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human... more
Protected area targets post-2020  Science Magazine · 2 weeks
Outcome-based targets are needed to achieve biodiversity goals. more
Radiolabeled protein lights up tumor to reveal where cancer drugs are working  NEWS MEDICAL · 4 weeks
Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography scans to calculate in real time how much of an... more
Potential drug targets cause of adult-onset muscular dystrophy  NEWS MEDICAL · 3 weeks
People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that generates toxic material within their cells. more
Medical News Today: Exercises and stretches for hip pain
MNT
Understanding the periodic table through the lens of the volatile Group I metals
PHYS.ORG
Synthesizing Modified and Pharmaceutically Relevant Peptides
NEWS MEDICAL
Scientists create first billion-atom biomolecular simulation
PHYS.ORG
How NASA Earth data aids America, state by state
PHYS.ORG
How the social lives of animals should form part of our conservation culture
PHYS.ORG
Deep sea scientist breaks British depth record
PHYS.ORG
Researchers develop new platform that recreates cancer in a dish to quickly determine the best bacterial therapy
PHYS.ORG
Smart antioxidant-containing polymer responds to body chemistry, environment
PHYS.ORG
Spinning new targets for accelerators
PHYS.ORG
Medical News Today: 'Empathetic technology': Can devices know what you're feeling?
MNT
Attention skills in a nonhuman cooperative breeding species
PHYS.ORG
New species of early human found in the Philippines
PHYS.ORG
Can someone tell me what a PBM does?
NEWS MEDICAL
Video: The chemistry behind color-changing birds
PHYS.ORG
Fresh