Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length.... MNT · 2 months
'Druggable' mechanism of tau protein pathology discovered  SCIENCE DAILY · 4 weeks
Researchers have uncovered a 'druggable' mechanism of pathological tau protein aggregation -- a significant advance toward finding an effective treatment for early-stage neurodegenerative diseases. more
Researchers use experimental PET to detect abnormal tau in brains of living former NFL players  NEWS MEDICAL · 2 weeks
Using an experimental positron emission tomography scan, researchers have found elevated amounts of abnormal tau protein in brain... more
Scientists develop technique to clear abnormal tau protein from human neurons  NEWS MEDICAL · 2 weeks
Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital... more
Neuroscientists propose new theory about amyloid precursor protein connection in Alzheimer's  NEWS MEDICAL · 3 days
Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops... more
Experimental PET scan detects abnormal tau protein in brains of living former NFL players  SCIENCE DAILY · 2 weeks
Using an experimental positron emission tomography (PET) scan, researchers have found elevated amounts of abnormal tau protein in brain regions... more
Drug that looks at Alzheimer’s differently ready for its first in-human testing  NEWS MEDICAL · 3 weeks
Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. more
ADDF’s new initiative aims to advance digital tools for Alzheimer's and dementias  NEWS MEDICAL · 3 weeks
As part of its Diagnostics Accelerator research program, the Alzheimer's Drug Discovery Foundation announced today a new initiative that aims to fast-track the development... more
Gum bacteria implicated in Alzheimer's and other diseases  SCIENCE DAILY · 3 weeks
Researchers are reporting new findings on how bacteria involved in gum disease can travel throughout the body, exuding toxins connected with Alzheimer's disease, rheumatoid arthritis and aspiration pneumonia. They detected evidence of... more
APOE gene impacts sleep depending on gender and severity of Alzheimer's  NEWS MEDICAL · 1 week
The gene most often associated with risk of Alzheimer's Disease impacts sleep depending on gender and the severity of Alzheimer's in a patient, suggests a study... more
NSAIDs ineffective for treatment or prevention of Alzheimer's disease  NEWS MEDICAL · 3 weeks
Researchers have known for decades that inflammation accompanies Alzheimer's disease (AD) brain lesions. more
How fish brain cells react to Alzheimer's disease  SCIENCE DAILY · 2 days
Researchers have studied the regenerative capacity of zebrafish brain in single cell resolution with the aim of developing novel strategies against Alzheimer's. more
DNA is managed like climbers' rope to help keep tangles at bay  SCIENCE DAILY · 4 days
Scientists have uncovered a process in cells that prevents DNA from becoming tangled, which resembles a method used to control climbers' ropes. more
Gum disease bacterium releases toxins that may cause Alzheimer's  NEWS MEDICAL · 3 weeks
Researchers have provided the strongest evidence to date that a bacterium involved in periodontitis contributes to the development of Alzheimer’s disease, rheumatoid arthritis and aspiration pneumonia. more
Alzheimer's diagnosis, management improved by brain scans  SCIENCE DAILY · 3 weeks
A first-of-its-kind national study has found that a form of brain imaging that detects Alzheimer's-related 'plaques' significantly influenced clinical management of patients with mild cognitive impairment and dementia. more
Secondary nucleation and elongation occur at different sites on Alzheimers amyloid-{beta} aggregates  Science Magazine · 1 week
The aggregates of the Aβ peptide associated with Alzheimer’s disease are able to both grow in size as well as generate, through secondary nucleation,... more
Eyes reveal early Alzheimer's disease  SCIENCE DAILY · 3 weeks
Reduced blood capillaries in the back of the eye may be a new, noninvasive way to diagnose early cognitive impairment, the precursor to Alzheimer's disease in which individuals become forgetful, reports a new study. Scientists detected these vascular... more
A video game aids in research on Alzheimer's disease  SCIENCE DAILY · 1 day
A new study based on data collected from a spatial navigation video game has shown that poor spatial orientation as an indicator can help in early diagnosis of Alzheimer's disease,... more
New research finds anti-inflammatory drugs to be ineffective to prevent Alzheimer’s  NEWS MEDICAL · 3 weeks
Researchers have known for decades that inflammation accompanies Alzheimer's disease brain lesions. Several early studies suggested that "super-aspirins" or Nonsteroidal anti-inflammatory drugs could help avoid the... more
New PET imaging biomarker could better predict progression of Alzheimer's disease  SCIENCE DAILY · 3 weeks
Researchers have discovered a way to better predict progression of Alzheimer's disease. A study utilizing positron emission tomography to image microglial activation levels showed that these... more
Thiazide use linked with reduced risk of low energy fractures in people with Alzheimer's  NEWS MEDICAL · 3 days
The use of thiazide diuretics was associated with a decreased risk of low energy fractures in people with Alzheimer's disease,... more
More evidence that blood tests can detect the risk of Alzheimer's  SCIENCE DAILY · 2 days
A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain. The researchers analyzed neurofilament light... more
Scientists identify two, extremely rare genetic variants linked to Alzheimer disease  NEWS MEDICAL · 4 weeks
Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time. more
New mobile phone game can detect people at risk of Alzheimer's  NEWS MEDICAL · 2 days
A specially designed mobile phone game can detect people at risk of Alzheimer's - according to new research from the University of East Anglia. more
Plants grow less in hotter temperatures  SCIENCE DAILY · 3 weeks
Researchers report how two transcription factors, ANAC044 and ANAC085, pause the cell cycle when cells experience stress. Mutations in ANAC044 and ANAC085 allowed cells to grow despite DNA damage or oppressive heat. The discovery provides new... more
Scientists propose new theory on Alzheimer's, amyloid connection  SCIENCE DAILY · 2 days
'Is amyloid precursor protein the mastermind behind Alzheimer's or is it just an accomplice?' Researchers devised a multi-functional reporter for amyloid precursor protein and tracked its localization and mobility, noticing a strange... more
PET images of microglial activation levels could better predict Alzheimer's disease progression  NEWS MEDICAL · 3 weeks
Researchers have discovered a way to better predict progression of Alzheimer's disease. By imaging microglial activation levels with positron emission tomography, researchers were able... more
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