For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients' bodies, a study led by Dana-Farber Cancer Institute researchers suggests.... NEWS MEDICAL · 2 months
Harmful genetic mutations in healthy donors' stem cells may create problems in AML patients  NEWS MEDICAL · 6 days
A stem cell transplant - also called a bone marrow transplant - is a common treatment for blood cancers, such... more
Immunosupressant combination therapy for glioblastoma shows promise  NEWS MEDICAL · 4 weeks
Researchers from the University of Texas have found an immunosuppressing target for the treatment of glioblastoma. In mice studies the team has identified CD73 macrophages which could be used to treat the cancers. The... more
Targeted deletion of PD-1 in myeloid cells induces antitumor immunity  Science Magazine · 3 weeks
PD-1, a T cell checkpoint receptor and target of cancer immunotherapy, is also expressed on myeloid cells. The role of myeloid-specific versus T cell–specific PD-1 ablation on antitumor... more
University of Missouri engineers design new 'wearable air conditioning'  NEWS MEDICAL · 2 weeks
One day, soldiers could cool down on the military battlefield -- preventing heat stroke or exhaustion -- by using "wearable air conditioning," an on-skin device designed by engineers at the... more
Mediterranean diet may help protect transplant recipients' kidney health  NEWS MEDICAL · 3 weeks
A new study indicates that following the Mediterranean diet may help kidney transplant recipients maintain transplant kidney function. The findings appear in an upcoming issue of CJASN. more
InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success  NEWS MEDICAL · 1 week
InDepth Pharmaceuticals, founded by Deepak Nihalani, Ph.D., the SmartState Endowed Chair in Renal Disease Biomarkers at the Medical University of South Carolina, has taken a vital... more
Novel biomaterial shows promise in treating cerebral aneurysms  NEWS MEDICAL · 2 weeks
Tim Becker, an associate professor of practice in the Department of Mechanical Engineering at Northern Arizona University, is developing a polypropylene glycol-based biomaterial called PPODA-QT, which is similar to body tissue, to... more
Cheap drug may alleviate treatment-resistance in leukemia  SCIENCE DAILY · 5 days
A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. The researchers will now launch a... more
MGH surgeons perform first-of-its-kind heart transplant in New England  NEWS MEDICAL · 2 weeks
A team of surgeons and specialists at Massachusetts General Hospital is announcing an achievement in transplant surgery today, having recently performed the largest number of adult heart transplants in the... more
Inexpensive drug may be used to counteract treatment resistance in patients with leukemia  NEWS MEDICAL · 5 days
A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia, one of the most... more
New closed-loop system offers promise as novel treatment for post-bariatric hypoglycemia  SCIENCE DAILY · 2 weeks
Post-bariatric hypoglycemia is a profoundly life-altering condition for patients. Having unpredictable hypoglycemia that people can't detect is really an unsafe situation. Researchers have developed a closed-loop... more
In health care, does “hotspotting” make patients better?  MIT · 2 weeks
Study shows no effect from program intended to reduce repeated hospitalizations by targeting high-cost patients. more
Danish study shows overweight and obesity are linked to higher risks of common cancers  NEWS MEDICAL · 2 weeks
Overweight and obesity were associated with higher risks of several common cancers in a 40-year, nationwide Danish study. more
Study shows how treatment resistance develops in patients with bile duct cancer  NEWS MEDICAL · 1 week
A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove... more
High BMI may improve the chance of survival in certain cancers  NEWS MEDICAL · 4 weeks
Above average or high BMI - often linked to cancers, diabetes, cardiovascular and other diseases - may in some cases improve the chance of survival among... more
Prostate cancer deaths are on the rise, shows new ACS report  NEWS MEDICAL · 2 weeks
Despite most cancers seeing a drop in deaths, prostate cancer deaths are on the rise in the U.S. New reporting from the American Cancer Society shows... more
Researchers identify new protein that shows promise for treating atherosclerosis  NEWS MEDICAL · 8 hours
Foxtail millet is an annual grass grown widely as a cereal crop in parts of India, China and Southeast Asia. Milling the grain removes the hard outer layer,... more
Study shows abnormal cardiovascular response to nitroglycerin in migraine patients  NEWS MEDICAL · 4 weeks
A clinical investigation recently published in the journal Cephalalgia, the official journal of the International Headache Society, suggests that migraine patients may exhibit a systemic pathophysiological alteration. more
Biomaterial-based vaccine has potential to completely eliminate AML cells  NEWS MEDICAL · 1 week
Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML... more
Young people feel there are fewer opportunities for them to get involved in sports  PHYS.ORG · 8 hours
New year, new you, or so everyone says. Will 2020 be your year thanks to a change in diet or... more
Judo holds promise for reducing sedentary behavior among children with autism  NEWS MEDICAL · 2 weeks
Judo may be just the right sport to increase the physical activity level among children with autism spectrum disorder and holds promise for reducing sedentary behavior,... more
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection  Science Magazine · 4 hours
Extreme pathophysiological stressors induce expansion of otherwise infrequent leukocyte populations. Here, we found a previously unidentified CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection... more
New blood test can help identify elderly concussion patients with brain tissue damage  NEWS MEDICAL · 2 weeks
Novel research shows that a blood test can differentiate elderly concussion patients with brain tissue damage from those without it. This finding,... more
21-gene recurrence score can aid in radiation decision-making, shows study  NEWS MEDICAL · 2 weeks
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New way that immune cells detect infections and cancers  SCIENCE DAILY · 2 weeks
Researchers have determined the molecular basis for how an important component of the immune system, called gamma-delta T cells, detects infections and cancers. more
Wearable air conditioning without needing electricity  nanowerk · 2 weeks
Engineers design on-skin electronic device providing a personal air conditioner without needing electricity. more
House Energy and Commerce Committee scheduled to hold hearing on immunosuppressive drug coverage  NEWS MEDICAL · 2 weeks
The House Energy and Commerce Committee is scheduled to hold a hearing on Wednesday, January 8, on the Comprehensive Immunosuppressive Drug Coverage... more
Effort To Control Opioids In An ER Leaves Some Sickle Cell Patients In Pain  NPR · 3 weeks
People with sickle cell disease aren't fueling the opioid crisis, research shows. Yet some ER doctors still treat patients seeking... more
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