Researchers have developed a new tool -- dubbed SATI -- to edit the mouse genome, enabling the team to target a broad range of mutations and cell types. The new genome-editing technology could be expanded for use in a broad range of gene mutation conditions such as Huntington's disease and the rare premature aging syndrome, progeria.... SCIENCE DAILY · 6 months
Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events  Science Magazine · 6 days
CRISPR-Cas9–mediated homology-directed DNA repair is the method of choice for precise gene editing in a wide range of model organisms, including mouse and human.... more
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Mutations in 38 different types of cancer have been mapped by means of whole genome analysis by an international team of researchers. A catalogue of the cancer mutations will be available worldwide... more
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In a first, scientists have used gene-editing technology to create "designer" immune system cells that can fight tumors and survive for months in cancer patients' bodies. more
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Record-breaking terahertz laser beam  SCIENCE DAILY · 4 weeks
Terahertz radiation is used for security checks at airports, for medical examinations and also for quality checks in industry. However, radiation in the terahertz range is extremely difficult to generate. Scientists have now succeeded in developing a terahertz radiation source... more
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Using a single-needle biopsy and new technology for tumor diagnosis developed by Baylor College of Medicine and the Broad Institute of MIT and Harvard, researchers have been able to provide... more
France goes soggy on using CRISPR technique for veggies  PHYS.ORG · 2 weeks
France's highest administrative court decided Friday that plants produced using new gene editing techniques such as CRISPR undergo strict testing as genetically modified organisms in a ruling that could see... more
Physically producing computer-generated artificial genomes to understand DNA  PHYS.ORG · 4 days
The molecular blueprint of life is stored in DNA within the genome. The digital revolution in biology, driven by DNA sequencing, enables scientists to read the genomes of the many microbes and... more
Minigenes produced by CRISPR combat liver disease in mice  NEWS MEDICAL · 6 days
A new gene-editing technique based on CRISPR was used to successfully avoid the development of a liver disease that can be caused by hundreds of mutations, as well as to... more
Printing objects that can incorporate living organisms  MIT · 4 weeks
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Cardiac and visual degeneration compensated by taurine supplement  NEWS MEDICAL · 4 weeks
Our genome consists of 20,000 genes, all of which may be capable of triggering disease. It is estimated that there are 7,000 unknown genes that cause recessive genetic diseases resulting from mutations... more
New nanosensor detects cancer biomarkers in drop of blood  nanowerk · 5 days
Researchers developed a nanosensor able to accurately detect biomarkers for cancer in an extremely broad range of concentrations: from 10 particles per microliter to a million particles per microliter. more
Reproductive genome from the laboratory  SCIENCE DAILY · 12 minutes
Researchers have for the first time developed a genome the size of a minimal cell that can copy itself. more
Solving the riddle of strigolactone biosynthesis in plants  SCIENCE DAILY · 3 weeks
Researchers have discovered the orobanchol synthase responsible for converting the strigolactone (SL) carlactonoic acid, which promotes symbiotic relationships with fungi, into the SL orobanchol, which causes root parasitic weeds to germinate. By... more
Bayer and Meiogenix join forces to advance agricultural research and development  NEWS MEDICAL · 1 week
Bayer and Meiogenix, a biotech company focused on next-generation breeding technologies, announced today a collaboration to advance agricultural research and development by accelerating the development of... more
Building better base editors  PHYS.ORG · 1 week
CRISPR-based gene editing has potential therapeutic benefits but also some technical shortcomings. One set of these gene editing tools, base editors, can rewrite the four individual DNA letters, or bases— A, C, T or G—which represent key chemical building blocks... more
Scientists boost gene-editing tools to new heights in human stem cells  SCIENCE DAILY · 3 weeks
Scientists have developed a new TREE method (an acronym short for transient reporter for editing enrichment, or TREE), which allows for bulk enrichment of DNA base-edited... more
Rogue cells at root of autoimmune disease  SCIENCE DAILY · 4 days
Breakthrough cellular genomics technology has allowed researchers to reveal genetic mutations causing rogue behavior in the cells that cause autoimmune disease. more
New tool monitors real time mutations in flu  PHYS.ORG · 2 weeks
A Rutgers-led team has developed a tool to monitor influenza A virus mutations in real time, which could help virologists learn how to stop viruses from replicating. more
Bioengineers developing organisms without biological parents  PHYS.ORG · 1 day
Bioengineers are on the brink of developing artificial organisms that will open up new applications in medicine and industry. Beat Christen discusses their risks and benefits. more
New tool monitors real time mutations in flu  SCIENCE DAILY · 2 weeks
A team has developed a tool to monitor influenza A virus mutations in real time, which could help virologists learn how to stop viruses from replicating. more
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