Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human brain development.... NEWS MEDICAL · 6 days
Scientists identify gene as master regulator in schizophrenia  SCIENCE DAILY · 6 days
Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human... more
Scientists discover major regulator of schizophrenia that is active during early development  NEWS MEDICAL · 5 days
Researchers have discovered a gene that acts as a master regulator of schizophrenia during the early stages of human brain development. more
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia  Science Magazine · 6 days
Applying tissue-specific deconvolution of transcriptional networks to identify their master regulators (MRs) in neuropsychiatric disorders has been largely unexplored. Here, using two schizophrenia (SCZ)... more
Regulator of first responder cells to brain injury  SCIENCE DAILY · 1 week
Researchers identified nuclear factor I-A (NFIA) as a central regulator of both the generation and activity of reactive astrocytes. more
'Key player' identified in genetic link to psychiatric conditions  SCIENCE DAILY · 4 weeks
Scientists have identified a specific gene they believe could be a key player in the changes in brain structure seen in several psychiatric conditions, such as schizophrenia and autism. more
[Editors' Choice] Alternative rhythms in schizophrenia  Science Magazine · 4 weeks
A distinct set of rhythmically expressed genes related to mitochondrial function is identified in the brains of patients with schizophrenia. more
Scientists identify specific gene that plays key role in several psychiatric conditions  NEWS MEDICAL · 4 weeks
Scientists have identified a specific gene they believe could be a key player in the changes in brain structure seen in several psychiatric conditions,... more
Gene linked to needing less sleep identified  SCIENCE DAILY · 3 weeks
The genetics of circadian rhythms have been well studied in recent years, but much less is known about other types of genes that play a role in sleep. Now, by studying a family with... more
The neurobiological mechanisms behind schizophrenia may depend on gender  SCIENCE DAILY · 2 weeks
The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study... more
Getting to the root of how plants tolerate too much iron  SCIENCE DAILY · 3 weeks
Scientists have found a major genetic regulator of iron tolerance, a gene called GSNOR. The findings could lead to the development of crop species that produce... more
Research team discovers gene critical for human eye, brain and limb development  NEWS MEDICAL · 4 weeks
An international collaboration led by a team at Oxford Brookes University has identified an important new gene which could open up new doors for... more
Preventing the onset of schizophrenia in mouse model  SCIENCE DAILY · 1 week
Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse model of schizophrenia,... more
Researchers investigate how to prevent the onset of schizophrenia using mouse model  NEWS MEDICAL · 1 week
Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed... more
New lipid signaling target may improve T cell immunotherapy  SCIENCE DAILY · 4 weeks
T cell immunotherapy uses the immune system to kill cancer cells. To increase the efficacy of this new treatment, researchers aimed to discover a master regulator of T cell fate.... more
Dietary supplement may help with schizophrenia  SCIENCE DAILY · 1 week
A dietary supplement, sarcosine, may help with schizophrenia as part of a holistic approach complementing antipsychotic medication, according to a researcher. more
Neurobiological pathophysiology of schizophrenia differs based on gender  NEWS MEDICAL · 2 weeks
The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study. more
Risk for schizophrenia and bipolar disorder has distinct effects on the brain  NEWS MEDICAL · 4 weeks
Brain abnormalities in people at familial risk of schizophrenia and bipolar disorder emerge in unique patterns, despite the symptom and genetic overlap of the... more
UC San Francisco scientists identify second 'short sleep' gene after 10-year search  NEWS MEDICAL · 3 weeks
After a decade of searching, the UC San Francisco scientists who identified the only human gene known to promote "natural short sleep" -- lifelong,... more
Signal blocks stem cell division in geriatric brain  SCIENCE DAILY · 3 weeks
Scientists have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation. According to the researchers, the gene regulator Id4 controls whether... more
Risk of psychotic disorders has disease-specific brain effects  SCIENCE DAILY · 4 weeks
Brain abnormalities in people at familial risk of schizophrenia and bipolar disorder emerge in unique patterns, despite the symptom and genetic overlap of the disorders, according to a new study. Similarities between... more
Many psychiatric disorders have heightened impulsivity  SCIENCE DAILY · 3 weeks
The study analyzed data from studies across eight different psychiatric disorders, including major depressive disorder, bipolar disorder, borderline personality disorder, schizophrenia, eating disorders, and others. The largest delay discounting effects were found to be associated with... more
Researchers Create Albino Lizards Using CRISPR-Cas9 Gene Editing  SCI-NEWS.COM · 2 weeks
A team of scientists at the University of Georgia has used CRISPR-Cas9 gene editing to engineer brown anoles (Anolis sagrei)... more
Gene linked to autism undergoes changes in men's sperm after pot use  SCIENCE DAILY · 3 weeks
A specific gene associated with autism appears to undergo changes in the sperm of men who use marijuana, according to new research. The gene... more
These albino lizards are the world's first gene-edited reptiles  SCIENCE DAILY · 3 weeks
Meet the world's first gene-edited reptiles: albino lizards roughly the size of your index finger. Researchers used CRISPR-Cas9 to make the lizards, providing a technique for gene editing outside of... more
Cancer disease incidence and severity influenced by gene mutation, tissue location  NEWS MEDICAL · 5 days
The KRAS gene is one of the commonly mutated genes in cancer. More than 40 percent of colorectal cancers have a mutated KRAS gene, or oncogene,... more
These albino lizards are the world's first gene-edited reptiles  PHYS.ORG · 3 weeks
Meet the world's first gene-edited reptiles: albino lizards roughly the size of your index finger. Researchers used CRISPR-Cas9 to make the lizards, providing a technique for gene editing outside of... more
Nanocapsules packed with gene-editing tools could be promising platform for many gene therapies  NEWS MEDICAL · 1 week
New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But... more
Future-proofing cereals for climate change drought conditions  PHYS.ORG · 2 weeks
Scientists at Heriot-Watt University have identified a gene responsible for drought resistance in barley which, it is believed, could help future-proof the cereals industry to increasingly dry conditions as climate change gathers pace. more
Hi-tech bacteria gene tool could prove productive  SCIENCE DAILY · 3 weeks
Bacteria could be used to produce large quantities of medicines and fuels using a new gene programming technique, research suggests. more
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