Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human brain development.... NEWS MEDICAL · 5 months
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A multidisciplinary team of researchers at Japan's Tohoku University has found that a gene regulator, called BACH1, facilitates the spread of pancreatic cancer to other parts of the body. more
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Putting a finger on the switch of chronic parasite infection  MIT · 4 weeks
Researchers find master regulator needed for Toxoplasma gondii parasite to chronically infect host; promising step toward infection treatment, prevention. more
Mechanism for how common gene therapy vectors enter cells  SCIENCE DAILY · 4 weeks
Researchers have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types -- the most commonly used viral vectors for in vivo gene therapy. The researchers identified that... more
Study offers significant promise for treating an aspect of schizophrenia  NEWS MEDICAL · 3 weeks
Research by a University of Georgia psychologist shows that targeting one particular symptom of schizophrenia has a positive effect on other symptoms, offering significant promise for treating an... more
Research offers promise for treating schizophrenia  SCIENCE DAILY · 3 weeks
Psychologists show that targeting one particular symptom of schizophrenia has a positive effect on other symptoms. more
New study provides clear picture of brain abnormalities associated with schizophrenia  NEWS MEDICAL · 6 days
What if the key to a better understanding of schizophrenia has been here all along--but researchers haven't had the resources to study it? more
Unraveling mechanisms of ventricular enlargement linked to schizophrenia  SCIENCE DAILY · 3 days
Scientists have implicated two microRNAs in the biological processes that underlie the ventricle enlargement observed in models of schizophrenia. more
Genetics of schizophrenia in the South African Xhosa  Science Magazine · 3 weeks
Africa, the ancestral home of all modern humans, is the most informative continent for understanding the human genome and its contribution to complex disease. To better understand the genetics of schizophrenia, we... more
ZGLP1 is a determinant for the oogenic fate in mice  Science Magazine · 5 days
Mammalian sexual reproduction relies on the dichotomy of male and female germ cell development. However, the underlying mechanisms remain unclear. Here, we show that ZGLP1, a conserved transcriptional... more
Key modifier identified in large genetic deletion related to neurodevelopmental disorders  SCIENCE DAILY · 3 days
Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes, according to new research. more
Transcription factor AP2 controls cnidarian germ cell induction  Science Magazine · 5 days
Clonal animals do not sequester a germ line during embryogenesis. Instead, they have adult stem cells that contribute to somatic tissues or gametes. How germ fate is induced in these animals, and... more
Scientists unravel mechanisms that lead to ventricular enlargement in schizophrenia  NEWS MEDICAL · 4 days
Enlarged cerebral ventricles are found in 80% of individuals with schizophrenia, yet the mechanisms that lead to ventricular enlargement are mostly unknown. more
New roles found for Huntington's disease protein  SCIENCE DAILY · 4 weeks
A research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease. Using genetic mouse models, they have discovered that... more
Novel palladium compound acts against ovarian tumor cells  NEWS MEDICAL · 3 weeks
A group led by a researcher affiliated with the University of São Paulo's São Carlos Chemistry Institute (IQSC-USP) in Brazil has developed a novel palladium compound that acts against ovarian tumor cells... more
Possible Alzheimer's breakthrough suggested  SCIENCE DAILY · 4 weeks
Researchers say they have identified a previously unknown gene and associated protein (which they have named 'aggregatin') which could potentially be suppressed to slow the advance of Alzheimer's disease. more
Research team identifies new roles for Huntington's Disease protein  NEWS MEDICAL · 4 weeks
A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease. more
Case Western researchers suggest potential Alzheimer's breakthrough  NEWS MEDICAL · 4 weeks
Researchers at the Case Western University School of Medicine say they have identified a previously unknown gene and associated protein which could potentially be suppressed to slow the advance of Alzheimer's disease. more
Scientists discover new drug target for prostate cancer in the non-coding genome  NEWS MEDICAL · 4 weeks
Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design. more
Increased risk of uterine cancer linked to 24 gene variants  NEWS MEDICAL · 1 day
The risk of uterine endometrial cancer is increased by 24 gene variants that code for different cellular processes such as cell growth and death, gene regulation, and estrogen... more
Scientists come together to better understand patented innovations available for gene therapy  NEWS MEDICAL · 1 week
The global gene therapy market is expected to reach $13 billion by 2024 as new treatment options target cancers and other diseases. more
Defective ATP13A2 gene can lead to Parkinson's disease, shows study  NEWS MEDICAL · 3 weeks
Biomedical scientists at KU Leuven have discovered that a defect in the ATP13A2 gene causes cell death by disrupting the cellular transport of polyamines. more
New tool probes gene regulation  PHYS.ORG · 2 weeks
DNA methylation (DNAme) is a modification of the genome—an epigenetic "mark"—that is required for proper cellular differentiation. It has been implicated in the regulation of gene expression, but its role in this stepwise process is poorly understood. more
Scientists create listeriosis-immune mice by turning off gene in myeloid cells  PHYS.ORG · 3 weeks
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Scientists identify gene that puts brakes on tissue growth  SCIENCE DAILY · 4 weeks
The planarian flatworm is a simple animal with a mighty ability: it can regenerate itself from nearly every imaginable injury, including decapitation. Scientists have studied these worms for decades to... more
Novel techniques for mining patented gene therapies offer promising treatment options  SCIENCE DAILY · 2 weeks
Scientists are working to gain a better understand of the growing number of worldwide patented innovations available for gene therapy treatment. more
ECDC updates risk assessment of novel coronavirus outbreak for Europe  NEWS MEDICAL · 4 weeks
The novel coronavirus (2019-nCoV) identified in China is a new strain of coronavirus that has not been previously identified in humans. more
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