Microbiology
Study reveals new and surprising function of adenine nucleotide translocator  NEWS MEDICAL · 1 hour
Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles,... more
UCLA research identifies potential strategy that may halt Huntington's disease  NEWS MEDICAL · 1 hour
A new study examining the role that star-shaped brain cells called astrocytes play in Huntington's disease has identified a potential strategy that may halt the disease and repair... more
Study represents a major step in seeking alternative cancer treatments for non-responders  NEWS MEDICAL · 1 hour
Research led by VHIO's Alena Gros signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low... more
Epigenetic changes can lead to development of GISTs, other cancers  NEWS MEDICAL · 2 hours
Most cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be effectively targeted with drugs that inhibit... more
Controlled ploidy reduction of pluripotent 4n cells generates 2n cells during mouse embryo development  Science Magazine · 3 hours
Cells with high ploidy content are common in mammalian extraembryonic and adult tissues. Cell-to-cell fusion generates polyploid cells during mammalian... more
A global synthesis reveals biodiversity-mediated benefits for crop production  Science Magazine · 3 hours
Human land use threatens global biodiversity and compromises multiple ecosystem functions critical to food production. Whether crop yield–related ecosystem services can be maintained by a few dominant species or rely... more
Targeting CCR5 trafficking to inhibit HIV-1 infection  Science Magazine · 3 hours
Using a cell-based assay monitoring differential protein transport in the secretory pathway coupled to high-content screening, we have identified three molecules that specifically reduce the delivery of the major co-receptor for HIV-1, CCR5, to... more
Chain formation can enhance the vertical migration of phytoplankton through turbulence  Science Magazine · 3 hours
Many species of motile phytoplankton can actively form long multicellular chains by remaining attached to one another after cell division. While chains swim more rapidly than... more
Current advances in research in treatment and recovery: Nicotine addiction  Science Magazine · 3 hours
The health harms of combusted tobacco use are undeniable. With market and regulatory pressures to reduce the harms of nicotine delivery by combustion, the tobacco product landscape has... more
DNA methylation reprogramming, TE derepression, and postzygotic isolation of nascent animal species  Science Magazine · 3 hours
The genomic shock hypothesis stipulates that the stress associated with divergent genome admixture can cause transposable element (TE) derepression, which could act as a... more
Common architecture of Tc toxins from human and insect pathogenic bacteria  Science Magazine · 3 hours
Tc toxins use a syringe-like mechanism to penetrate the membrane and translocate toxic enzymes into the host cytosol. They are composed of three components: TcA, TcB,... more
Synthetic presentation of noncanonical Wnt5a motif promotes mechanosensing-dependent differentiation of stem cells and regeneration  Science Magazine · 3 hours
Noncanonical Wnt signaling in stem cells is essential to numerous developmental events. However, no prior studies have capitalized on the... more
Structure and genome ejection mechanism of Staphylococcus aureus phage P68  Science Magazine · 3 hours
Phages infecting Staphylococcus aureus can be used as therapeutics against antibiotic-resistant bacterial infections. However, there is limited information about the mechanism of genome delivery of phages that infect... more
Epigenetic dynamics in infancy and the impact of maternal engagement  Science Magazine · 3 hours
The contribution of nature versus nurture to the development of human behavior has been debated for centuries. Here, we offer a piece to this complex puzzle by identifying... more
Cryo-electron microscopy structure and analysis of the P-Rex1-G{beta}{gamma} signaling scaffold  Science Magazine · 3 hours
PIP3-dependent Rac exchanger 1 (P-Rex1) is activated downstream of G protein–coupled receptors to promote neutrophil migration and metastasis. The structure of more than half of the enzyme and... more
[Research Articles] Astrocyte molecular signatures in Huntingtons disease  Science Magazine · 3 hours
Astrocytes are implicated in neurodegenerative disorders and may contribute to striatal neuron loss or dysfunction in Huntington’s disease (HD). Here, we assessed striatal astrocyte gene and protein signatures in two HD mouse... more
[Research Articles] Mutant neuropeptide S receptor reduces sleep duration with preserved memory consolidation  Science Magazine · 3 hours
Sleep is a crucial physiological process for our survival and cognitive performance, yet the factors controlling human sleep regulation remain poorly understood.... more
First widespread chytrid fungus infections in frogs of Peruvian Amazon rain forests  PHYS.ORG · 3 hours
University of Michigan biologists have documented, for the first time, the widespread presence of the notorious chytrid fungus in 80 species of frogs from... more
Study unveils the intricate way two proteins interact to promote cell movement, metastasis  PHYS.ORG · 3 hours
When cells in our bodies need to move—to attack an infection or heal a wound, for example—cellular proteins send and receive a... more
Study: Biodiversity improves crop production  PHYS.ORG · 3 hours
Ecologists and biologists compared data of about 1,500 agricultural fields around the world, including corn fields in the American plains, oilseed rape fields in southern Sweden, coffee plantations in India, mango plantations in South Africa and cereal crops... more
Computational 'match game' identifies potential antibiotics  SCIENCE DAILY · 3 hours
Computational biologists have devised a software tool that can play a high-speed 'Match Game' to identify bioactive molecules and the microbial genes that produce them so they can be evaluated as possible antibiotics and other therapeutic... more
New discovery paves way for better treatment of diabetes  NEWS MEDICAL · 3 hours
Insulin, a hormone essential for regulating blood sugar and lipids, is normally produced by pancreatic β cells. In many people with diabetes, however, pancreatic cells are not (or no longer)... more
Stony Brook-led study reveals how proteome collapse process drives cell death and aging  NEWS MEDICAL · 3 hours
Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study, to be... more
Diabetes: A next-generation therapy soon available?  SCIENCE DAILY · 4 hours
Insulin is normally produced by pancreatic beta cells. In many people with diabetes, pancreatic cells are not functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections. However,... more
Pioneering cell therapies for non-responders to current immunotherapies  SCIENCE DAILY · 4 hours
New research signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments. more
Study reports first evidence of biological changes related to e-cig use in never-smokers  NEWS MEDICAL · 4 hours
E-cigarette (e-cig) use is rising at concerning levels among both smokers and non-smokers, and new research data suggests that even short-term e-cig... more
X marks the spot: Recombination in structurally distinct chromosomes  SCIENCE DAILY · 4 hours
A recent study has revealed more details about how the synaptonemal complex performs its job, including some surprising subtleties in function. more
Scientists discover novel virus that may shed light on viral evolution  NEWS MEDICAL · 5 hours
Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue... more
Galapagos study highlights importance of biodiversity in the face of climate change  PHYS.ORG · 5 hours
As the world's climate continues to change, biologically diverse communities may be most capable of adapting to environmental challenges. more
X marks the spot: recombination in structurally distinct chromosomes  PHYS.ORG · 5 hours
Two years ago, scientists from the Stowers Institute for Medical Research reported the 3-D structure of the synaptonemal complex in the fruit fly Drosophila melanogaster. This large protein complex is... more
Study report first evidence of biological changes related to e-cig use in never-smokers  NEWS MEDICAL · 6 hours
E-cigarette (e-cig) use is rising at concerning levels among both smokers and non-smokers, and new research data suggests that even short-term e-cig... more
Computational 'match game' identifies potential antibiotics  PHYS.ORG · 6 hours
Computational biologists at Carnegie Mellon University have devised a software tool that can play a high-speed "Match Game" to identify bioactive molecules and the microbial genes that produce them so they can be evaluated as possible... more
New insights into biological underpinnings of schizophrenia  SCIENCE DAILY · 6 hours
Researchers have implicated 10 new genes in the development of schizophrenia using a method called whole exome sequencing, the analysis of the portion of DNA that codes for proteins. A global consortium of schizophrenia... more
Novel virus type may shed light on viral evolution  SCIENCE DAILY · 7 hours
Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens... more
Subtle changes in mitochondrial DNA can have profound consequences for patient's health  NEWS MEDICAL · 7 hours
Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health. more
Marine Biologists Discover Two New Species of Porcelain Crabs  SCI-NEWS.COM · 7 hours
A duo of marine biologists from the Smithsonian Tropical Research Institute in Panama and the Justus-Liebig-Universität in Germany... more
Researchers uncover novel virus type that may shed light on viral evolution  PHYS.ORG · 7 hours
Viruses are nonliving creatures consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself... more
Researchers develop machine learning tool to refine personalized immunotherapy  PHYS.ORG · 7 hours
Ludwig Cancer Research scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to helper T cells, which stimulate and... more
Tackling E. coli infections  PHYS.ORG · 7 hours
Monash scientists have identified a survival mechanism of bacteria that cause disease in plant and animals, including highly virulent E. coli (Escherichia coli) related diseases. more
Assessing the rationality of time investment when rock ants choose a nest site  PHYS.ORG · 7 hours
A team of researchers from the University of Oxford and Arizona State University has carried out experiments with rock ants to assess... more
'Industrial melanism' linked to same gene in three moth species  PHYS.ORG · 7 hours
The rise of dark forms of many species of moth in heavily polluted areas of 19th and 20th century Britain, known as industrial melanism, was a highly visible... more
Engineering biomimetic microvascular meshes for subcutaneous islet transplantation  PHYS.ORG · 8 hours
To successfully engineer cell or tissue implants, bioengineers must facilitate their metabolic requirements through vascular regeneration. However, it is challenging to develop a broad strategy for stable and functional vascularization. In a... more
New DNA 'clock' could help measure development in young children  SCIENCE DAILY · 8 hours
Scientists have developed a molecular 'clock' that could reshape how pediatricians measure and monitor childhood growth and potentially allow for an earlier diagnosis of life-altering development disorders. more
Frailty: The rising global health burden for an aging society  SCIENCE DAILY · 8 hours
Despite the evidence on risk factors for frailty, and the substantial progress that has been made in frailty awareness, the biological mechanisms underlying its development are still far... more
Glowing particles in the blood may help diagnose and monitor brain cancer  SCIENCE DAILY · 8 hours
A chemical that has improved surgeries for brain cancer by making tumor cells fluorescent may also help doctors safely diagnose the disease and monitor... more
New study may have the reason why heart medication gives muscle pain  SCIENCE DAILY · 8 hours
A research team found muscle cells treated with statins released the amino acid called glutamate at much higher levels than muscle cells that were... more
Gene mutation in the chloride channel triggers rare high blood pressure syndrome  SCIENCE DAILY · 8 hours
When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged... more
Inactive receptor renders cancer immunotherapies ineffective  SCIENCE DAILY · 8 hours
The aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective... more
Drug-light combo could offer control over CAR T-cell therapy  SCIENCE DAILY · 8 hours
Bioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR... more
Researchers solve puzzle about link between genetic mutations, mating in fruit flies  SCIENCE DAILY · 9 hours
More than a century ago, early geneticists showed that the inheritance of a single mutation by fruit flies can change the insect's body color... more
Cell family trees tracked to discover their role in tissue scarring and liver disease  SCIENCE DAILY · 9 hours
Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with... more
Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration  NEWS MEDICAL · 9 hours
Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration to expedite the development of automated microfluidic systems for rapid and high-throughput gene editing in mammalian cell lines. more
Sphere Fluidics closes $2 million USD (c. £1.5 million GBP) investment round  NEWS MEDICAL · 10 hours
Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, announced today that is has closed a $2 million... more
Sphere Fluidics hires 10 new UK and US staff in its plan to scale internationally  NEWS MEDICAL · 10 hours
Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, announced today that... more
Sphere Fluidics closes a $4.8 million USD (£3.7 million) funding round  NEWS MEDICAL · 10 hours
Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, announced today that it has closed an additional tranche of investment... more
Sphere Fluidics expands into additional facility at Granta Park in Cambridge, UK  NEWS MEDICAL · 10 hours
Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, announced today that it has opened a new office... more
Sphere Fluidics introduces Cyto-Cellect Human IgGK Detection Kit  NEWS MEDICAL · 10 hours
Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, today introduced the Cyto-Cellect™ Human IgGK Detection Kit, to be used in conjunction with the Cyto-Mine® Single... more
BioStreamline project outcomes  NEWS MEDICAL · 10 hours
CPI have reported successful outcomes the £11.2 million BioStreamline project – a collaborative project involving six partners across the UK including Lonza Biologics, UCB Celltech, Sphere Fluidics, Horizon Discovery, Alcyomics Ltd and CPI. more
Fido's raw meat pet food may be loaded with harmful bacteria: study  PHYS.ORG · 14 hours
Increasingly popular raw meat meals for dogs and cats may be full of multi-drug resistant bacteria, posing a serious risk to animals and humans,... more
NIH awards new contract to integrate pathogen and vector genomics database  NEWS MEDICAL · 15 hours
A team led by scientists at the University of Pennsylvania and University of Georgia provides thousands of researchers around the world with access to the Eukaryotic... more
Study: Genetic differences in the immune system shape bacteria that colonize the digestive system  NEWS MEDICAL · 15 hours
Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research... more
Researcher explores biological processes that cause fertility problems in humans  NEWS MEDICAL · 15 hours
With significant funding from the National Institutes of Health (NIH), a researcher at The University of Texas at Arlington is investigating fundamental biological processes that lead to fertility... more
Gut bacteria may counter the harmful effects of processed foods  MNT · 22 hours
A new mouse study identifies a specific bacterium that lives in our gut and breaks down harmful chemicals from processed foods into harmless byproducts. more
Tiny droplets allow bacteria to survive daytime dryness on leaves  SCIENCE DAILY · 22 hours
Microscopic droplets on the surface of leaves give refuge to bacteria that otherwise may not survive during the dry daytime, according to a new study. more
Drug-light combination could offer better control over CAR T-cell treatments  NEWS MEDICAL · 23 hours
Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control. more
Researchers track cell family trees to discover their role in tissue scarring and liver disease  NEWS MEDICAL · 24 hours
Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular... more
Medical News Today: Gut bacteria may counter the harmful effects of processed foods  MNT · 1 day
A new mouse study identifies a specific bacterium that lives in our gut and breaks down harmful chemicals from processed foods into... more
Medical News Today: What to know about influenza A  MNT · 1 day
Influenza A is a common type of the flu virus. Here, we discuss its symptoms and how to treat and prevent this highly contagious virus. more
A mathematical model reveals long-distance cell communication mechanism  SCIENCE DAILY · 1 day
An interdisciplinary collaborative team has identified how a large community can communicate with each other almost simultaneously even with very short distance signaling. more
CRISPR helps find difficult to detect cancer cells  NEWS MEDICAL · 1 day
Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in... more
Engineered communities of cells make long-distance calls  NEWS MEDICAL · 1 day
The search for effective biological tools is a marathon, not a sprint, even when the distances are on the microscale. A discovery at Rice University on how engineered communities of cells communicate is a... more
Koalas protect their germline cells against retroviral attack  NEWS MEDICAL · 1 day
In a new study published in the journal Cell, scientists have found that koala DNA is protected against attack by retroviruses by a special type of immune response, which distinguishes foreign DNA... more
Scientists develop more accurate method to find good targets for cancer immunotherapy  NEWS MEDICAL · 1 day
Ludwig Cancer Research scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to... more
Startled fish escape using several distinct neuronal circuits  PHYS.ORG · 1 day
A fast knee-jerk "ballistic" escape response and a more considered "delayed" escape response are mediated by distinct and parallel neuronal pathways in zebrafish, according to a study published October 15 in the... more
Widely Publicized Study on CRISPR Babies' Gene Mutation Now Retracted for Errors  LIVE SCIENCE · 1 day
A widely publicized study that suggested that the first gene-edited "CRISPR" babies could have shorter lifespans has been retracted due to crucial errors in... more
PerkinElmer introduces PG-Seq Rapid Non-Invasive PGT-A kit as alternative to IVF embryo biopsies  NEWS MEDICAL · 1 day
PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today introduced its PG-Seq Rapid Non-Invasive Preimplantation Genetic Testing for... more
UCLA researchers discover new way to eliminate leukemia stem cells  NEWS MEDICAL · 1 day
The introduction of the drug imatinib in 2001 revolutionized the treatment of a type of cancer called chronic myelogenous leukemia. In more than 80% of people with CML... more
Researchers reveal mechanism involved in altering DNA methylation in cancer  NEWS MEDICAL · 1 day
Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments... more
Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage  NEWS MEDICAL · 1 day
When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only... more
Sperm and egg cell 'immune response' protects koala DNA  SCIENCE DAILY · 1 day
Discovery of a type of immunity that protects koalas' DNA from viruses has importance for the survival of koalas and our fundamental understanding of evolution. A team of scientists are... more
Last year's extreme snowfall wiped out breeding of Arctic animals and plants  PHYS.ORG · 1 day
In 2018, vast amounts of snow were spread across most of the Arctic region and did not melt fully until late summer, if at... more
The lunar cycle drives the nightjar's migration  PHYS.ORG · 1 day
GPS tracking data reveals that the foraging activity of the European nightjar more than doubles during moon-lit nights, and the birds then migrate simultaneously about 10 days after the full moon, according to a... more
Synthetic cells make long-distance calls  SCIENCE DAILY · 1 day
Synthetic biologists design transcriptional circuits that allow single-cell microbes to form networks that spur collective action, even in large communities. The work could lead to engineered microbes that treat conditions in gut microbiomes or communicate with bioelectronics. more
Machine learning tool refines personalized immunotherapy  SCIENCE DAILY · 1 day
Scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to helper T cells, which stimulate and orchestrate the immune response to tumors and infectious agents. more
Inside the fuel cell: Imaging method promises industrial insight  SCIENCE DAILY · 1 day
Hydrogen-containing substances are important for many industries, but scientists have struggled to obtain detailed images to understand the element's behavior. Researchers now demonstrate the quantification of hydrogen for different states... more
Researchers release a new genome sequence of the date palm  PHYS.ORG · 1 day
Researchers at NYU Abu Dhabi's Center for Genomics and Systems Biology (NYUAD CGSB) and the UAEU Khalifa Center for Genetic Engineering and Biotechnology (KCGEB), working with other institutions,... more
Tiny droplets allow bacteria to survive daytime dryness on leaves  PHYS.ORG · 1 day
Microscopic droplets on the surface of leaves give refuge to bacteria that otherwise may not survive during the dry daytime, according to a new study published today in... more
How status sticks to genes  PHYS.ORG · 1 day
Those at the bottom of the social ladder are known to live shorter and sicker lives than those at the top. And the stress of life at the bottom may have long-term health effects that even upward mobility... more
Inside the fuel cell: Imaging method promises industrial insight  PHYS.ORG · 1 day
Hydrogen-containing substances are important for many industries, but scientists have struggled to obtain detailed images to understand the element's behavior. In Review of Scientific Instruments researchers demonstrate the quantification of... more
Researchers solve puzzle about link between genetic mutations, mating in fruit flies  PHYS.ORG · 1 day
More than a century ago, early geneticists showed that the inheritance of a single mutation by fruit flies can change the insect's body color... more
DNA fracturing rewires gene control in cancer  SCIENCE DAILY · 1 day
A multi-institutional team has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers. more
New method for quicker and simpler production of lipidated proteins  PHYS.ORG · 1 day
Some of the body's proteins are not just made up of amino acids, they are also 'decorated' with lipid chains, which significantly influence the biological functions of the... more
Researchers build a soft robot with neurologic capabilities  SCIENCE DAILY · 1 day
In work that combines a deep understanding of the biology of soft-bodied animals such as earthworms with advances in materials and electronic technologies, researchers have developed a robotic device containing a stretchable... more
Tissue damage caused by a heart attack to be reduced by 30%?  SCIENCE DAILY · 1 day
A heart attack is caused by a clot that blocks the artery blood flow. Under these conditions, the affected tissues undergo a rapid necrosis.... more
Many cooks don't spoil the broth: Manifold symbionts prepare the host for any eventuality  SCIENCE DAILY · 1 day
Deep-sea mussels, which rely on symbiotic bacteria for food, harbor a surprisingly high diversity of these bacterial 'cooks': Up to... more
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