Microbiology
Design principles for peroxidase-mimicking nanozymes  PHYS.ORG · 1 minute
Nanozymes, enzyme-like catalytic nanomaterials, are considered to be the next generation of enzyme mimics because they not only overcome natural enzymes' intrinsic limitations, but also possess unique properties in comparison with conventional artificial enzymes. Until now, lots of... more
Antibiotic resistances spread faster than so far thought  PHYS.ORG · 1 minute
By studying fish raised in aquaculture, researchers from the Helmholtz Zentrum München, the University of Copenhagen and the University of Campinas in Brazil have shed new light on the mechanisms by which... more
Physicists identify simple mechanism used by deadly bacteria to fend off antibiotics  NEWS MEDICAL · 8 minutes
Physicists at McMaster University have for the first time identified a simple mechanism used by potentially deadly bacteria to fend off antibiotics, a discovery... more
Linking sensing to signaling during plant immunity  PHYS.ORG · 38 minutes
Plant defense against invading pathogens relies upon effective recognition of non-self organisms and a subsequent signaling response characterized by reprogramming of host gene expression and localized cell death to combat infection and provide resistance.... more
Predicting sequence from structure  PHYS.ORG · 2 hours
One way to probe intricate biological systems is to block their components from interacting and see what happens. This method allows researchers to better understand cellular processes and functions, augmenting everyday laboratory experiments, diagnostic assays, and therapeutic interventions. As a... more
Physicists pinpoint a simple mechanism that makes bacteria resistant to antibiotics  PHYS.ORG · 2 hours
Physicists at McMaster University have for the first time identified a simple mechanism used by potentially deadly bacteria to fend off antibiotics, a discovery which is... more
Customizing the Cellular Microenvironment to Improve Physiological Relevance  NEWS MEDICAL · 2 hours
An interview with Marie-Charlotte Manus, discussing a new technology called PRIMO that improves the physiological relevance of cells in culture. more
Medical News Today: Parkinson's: How stem cells can help repair the brain  MNT · 3 hours
A new review examines the past, present, and future of stem cell therapy for replacing damaged brain cells in Parkinson's disease. more
Japan approves test of iPS cells for treating spinal injuries  REUTERS · 5 hours
Japanese scientists will test the use of human-induced pluripotent stem cells (iPS) to treat spinal cord... more
Researchers first to show hinge morphology of click beetle's latch mechanism  PHYS.ORG · 6 hours
Aimy Wissa, assistant professor of mechanical science and engineering (MechSE) at Illinois, leads an interdisciplinary research team to study click beetles to inspire more agile robots.... more
Combination of PARP inhibitor and immunotherapy results in tumor regression in SCLC mouse models  NEWS MEDICAL · 6 hours
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and... more
Activating gene that helps excite neurons reverses depression in male mice  NEWS MEDICAL · 6 hours
Directly activating a gene important to exciting our excitatory neurons and associated with major depression may help turn around classic symptoms like social isolation and loss... more
Patented IU discovery to treat ARDS has been optioned to Theratome Bio  NEWS MEDICAL · 9 hours
A patented Indiana University School of Medicine discovery that uses proteins, lipids and nucleic acids secreted by adult stem cells to treat Acute Respiratory... more
Virus-infected bacteria could provide help in the fight against climate change  PHYS.ORG · 18 hours
Viruses don't always kill their microbial hosts. In many cases, they develop a mutually beneficial relationship: the virus establishes itself inside the microbe and, in return,... more
Virus-infected bacteria could provide help in the fight against climate change  SCIENCE DAILY · 18 hours
Understanding the relationship between microbes and viruses is beneficial not only for medical research and practical applications but also in marine biology, say researchers. more
Promising drug developed to rejuvenate muscle cells  NEWS MEDICAL · 2 days
Researchers from The University of Texas Medical Branch at Galveston have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a study just published... more
New technique using patients' own modified cells could help treat Crohn's disease  NEWS MEDICAL · 2 days
A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with... more
Vapers develop cancer-related gene deregulation as cigarette smokers  NEWS MEDICAL · 2 days
If you think vaping is benign, think again. A small USC study shows that e-cig users develop some of the same cancer-related molecular changes in oral tissue as cigarette smokers, adding to... more
A weakness in a rare cancer that could be exploited with drugs  SCIENCE DAILY · 3 days
Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able... more
Study examines how compound damaged DNA to understand its connection to cancer  SCIENCE DAILY · 3 days
In an effort to understand how colibactin, a compound produced by certain strains of E. coli, may be connected to the development of colorectal... more
Genetic vulnerability to menthol cigarette use  SCIENCE DAILY · 3 days
A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive. The variant of the MRGPRX4 gene is five to eight times more frequent among... more
Drug to rejuvenate muscle cells  SCIENCE DAILY · 3 days
Researchers have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a new study. more
Hope for fighting disease known as Ebola of frogs  SCIENCE DAILY · 3 days
Despite widespread infection, some frog populations are surviving a deadly disease that is the equivalent of humankind's Ebola virus. The reason -- genetic diversity. more
Study shows hope for fighting disease known as Ebola of frogs  PHYS.ORG · 3 days
Despite widespread infection, some frog populations are surviving a deadly disease that is the equivalent of mankind's Ebola virus. The reason —genetic diversity. more
Patients' own cells could be the key to treating Crohn's disease  SCIENCE DAILY · 3 days
A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical... more
New live-imaging technique reveals cellular repair crew plugging leaky biological barrier  SCIENCE DAILY · 3 days
Suppose you live in a brick house and notice cracks in the mortar that let in cold air, rain and insect pests. You might call a... more
Year in space put US astronaut's disease defenses on alert  PHYS.ORG · 3 days
Nearly a year in space put astronaut Scott Kelly's immune system on high alert and changed the activity of some of his genes compared to his Earth-bound identical... more
In-memory computing on a photonic platform  Science Magazine · 3 days
Collocated data processing and storage are the norm in biological computing systems such as the mammalian brain. As our ability to create better hardware improves, new computational paradigms are being explored beyond von Neumann architectures. Integrated... more
On the origin of B1 cells  SCIENCE DAILY · 3 days
A new study may resolve a decades-old debate in immunology: researchers report that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's experiments show that a B1-typical B-cell receptor can... more
Biologists identify honeybee 'clean' genes known for improving survival  PHYS.ORG · 3 days
The key to breeding disease-resistant honeybees could lie in a group of genes—known for controlling hygienic behaviour—that enable colonies to limit the spread of harmful mites and bacteria, according to... more
In space, NASA heard astronaut's immune system scream  PHYS.ORG · 3 days
Nearly a year in space put astronaut Scott Kelly's immune system on high alert and changed the activity of some of his genes compared to his Earth-bound identical twin. more
'Cellular barcoding' reveals how breast cancer spreads  SCIENCE DAILY · 3 days
A cutting-edge technique called cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the main tumour into the blood and other organs. more
Nature Favors Production of Asymmetrical Pollen Grains  SCI-NEWS.COM · 3 days
According to a new study published in the journal Cell, plants favor the production of uneven, asymmetrical patterns on the surface of... more
Spare 10 minutes to make science leap forward  PHYS.ORG · 3 days
Today sees the launch of an innovative Citizen Science Project by Diamond Light Source, the UK's national synchrotron science facility.The project uses a crowdsourcing model to call on people of all ages... more
Exercise might improve health by increasing gut bacterial diversity  SCIENCE DAILY · 3 days
Research has suggested that the efficiency with which we transport oxygen to our tissues (cardiorespiratory fitness) is a far greater predictor of gut microbiota diversity than either body fat percentage... more
The friendly extortioner takes it all  PHYS.ORG · 3 days
Cooperating with other people makes many things easier. However, competition is also a characteristic aspect of our society. In their struggle for contracts and positions, people have to be more successful than their competitors and colleagues.... more
Virus-infested fungus could help cut chemical pesticides  PHYS.ORG · 3 days
The evidence against chemical pesticides is mounting. An estimated 7m people are at risk from exposure to pesticides globally, while a million a year suffer or die from pesticide associated diseases. And that says... more
In zebrafish eggs, most rapidly growing cell inhibits neighbors through mechanical signals  PHYS.ORG · 3 days
"The winner takes it all, the loser standing small"—that's not just true in the famous ABBA song, but also in animal development. Frequently, a... more
How proteins become embedded in a cell membrane  PHYS.ORG · 3 days
Many proteins with important biological functions are embedded in a biomembrane in the cells of humans and other living organisms. But how do they get in there in the first place? Researchers... more
UVA scientists find potential explanation for mysterious cell death in Alzheimer’s, Parkinson’s  NEWS MEDICAL · 3 days
Scientists at the University of Virginia School of Medicine have identified a potential explanation for the mysterious death of specific brain cells seen in... more
IDT expands its courier zones in the UK  NEWS MEDICAL · 3 days
As an advocate for researchers in the genomics age, Integrated DNA Technologies (IDT) is expanding its courier zones to ensure that the highest-fidelity oligos are available in less time and at the... more
Study: High intensity exercise may improve health by increasing gut microbiota diversity  NEWS MEDICAL · 3 days
Bacteria, often synonymous with infection and disease, may have an unfair reputation. Research indicates there are as many, if not more, bacterial cells in... more
Yellow, Blob-Like Cell Transforms into Wriggling Salamander in Surreal Time-Lapse Video  LIVE SCIENCE · 3 days
A mesmerizing 6-minute time lapse shows a single cell dividing seemingly endlessly until what was once a yellow blob has become a wriggling, darting salamander tadpole. more
Why Do Humans Hear So Well? You Can Thank the Tiny 'Jell-O' Violin Inside Your Ear  LIVE SCIENCE · 3 days
A teensy little "Jell-O" membrane in our ears may partly explain why humans have such amazing... more
Scientists implicate hidden genes in the severity of autism symptoms  NEWS MEDICAL · 3 days
Scientists at the University of Colorado Anschutz Medical Campus have implicated a largely hidden part of the human genome in the severity of autism symptoms, a discovery that... more
New method for improved visualization of single-cell RNA- sequencing data  NEWS MEDICAL · 3 days
Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop... more
Discovery of weakness in a rare cancer could be exploited with drugs  NEWS MEDICAL · 3 days
Cancer cells are, in some respects, impressive: They can grow relentlessly, sidestep the aging process by becoming immortal, and evade the immune system's persistent... more
Sausage mislabeling in Canada is down, new study finds  NEWS MEDICAL · 3 days
Sausage mislabelling in Canada is down, according to a new University of Guelph DNA barcoding study. more
Newly developed stem cell technologies show promise for treating PD patients  NEWS MEDICAL · 3 days
Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal... more
New mechanism for lateral inhibition of cells discovered  NEWS MEDICAL · 3 days
"The winner takes it all, the loser standing small" - that's not just true in the famous ABBA song, but also in animal development. Frequently, a group of cells starts out all... more
Moffitt researchers shed light on how CAR T cells function mechanistically  NEWS MEDICAL · 3 days
The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that... more
Platinum nanoparticles show selective toxicity against liver cancer cells  NEWS MEDICAL · 3 days
In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment. more
Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children  NEWS MEDICAL · 3 days
St. Jude Children's Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased... more
Cell manipulation could soon halt or reverse aging  NEWS MEDICAL · 3 days
Researchers have shown that tweaking the tiny inner parts of a cell could prevent the damage caused due to aging. more
Researchers use optogenetic tool to control, visualize receptor signals in neural cells  NEWS MEDICAL · 3 days
Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualized serotonin receptor signals in neural cells. To this end, they modified a... more
Lifetime adversity, increased neural processing during trauma combine to intensify core PTSD symptoms  NEWS MEDICAL · 3 days
Lifetime adversity and increased neural processing during a traumatic event combine to increase the frequency of intrusive traumatic memories and the distress... more
Hop to it: Researchers evaluate rabbits' evolved resistance to myxoma virus  SCIENCE DAILY · 4 days
Researchers have validated the role of specific rabbit genes in contributing to this acquired resistance. more
Can we repair the brain? The promise of stem cell technologies for treating Parkinson's disease  SCIENCE DAILY · 4 days
Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future.... more
Improved RNA data visualization method gets to the bigger picture faster  SCIENCE DAILY · 4 days
Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers... more
Improved RNA data visualization method gets to the bigger picture faster  PHYS.ORG · 4 days
Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers... more
World Health Organization Forms Committee To Guide Editing Of Human Genes  NPR · 4 days
WHO acted in reaction to a Chinese scientist's announcement in 2018 that he had created the world's first gene-edited babies, a step that highlighted the need... more
Parallel adaptation of rabbit populations to myxoma virus  Science Magazine · 4 days
In the 1950s the myxoma virus was released into European rabbit populations in Australia and Europe, decimating populations and resulting in the rapid evolution of resistance. We investigated the genetic basis of... more
On the origin of B1 cells  PHYS.ORG · 4 days
A new MDC study may resolve a decades-old debate in immunology. A team led by Professor Klaus Rajewsky reports in Science that distinct progenitor cells are not required for the development of B1 cells. Instead, the... more
Penis development needs more than just testes and testosterone  PHYS.ORG · 4 days
Proper development of the fetal penis requires not just testosterone from the testes, but a second hormone produced by other tissues, including the placenta, according to a new study publishing... more
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein  Science Magazine · 4 days
ABCB1, also known as P-glycoprotein, actively extrudes xenobiotic compounds across the plasma membrane of diverse cells, which contributes to cellular drug resistance and interferes with therapeutic drug delivery.... more
How a circularized tmRNA moves through the ribosome  Science Magazine · 4 days
During trans-translation, transfer-messenger RNA (tmRNA) and small protein B (SmpB) together rescue ribosomes stalled on a truncated mRNA and tag the nascent polypeptide for degradation. We used cryo–electron microscopy to determine the... more
BCR-dependent lineage plasticity in mature B cells  Science Magazine · 4 days
B2 cells engage in classical antibody responses, whereas B1 cells are considered carriers of innate immunity, biased toward recognizing epitopes present on the surfaces of common pathogens and self antigens. To explore the role... more
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity  Science Magazine · 4 days
How hexanucleotide GGGGCC (G4C2) repeat expansions in C9orf72 cause frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is not understood. We developed a mouse model engineered to express... more
The human gut bacterial genotoxin colibactin alkylates DNA  Science Magazine · 4 days
Certain Escherichia coli strains residing in the human gut produce colibactin, a small-molecule genotoxin implicated in colorectal cancer pathogenesis. However, colibactin’s chemical structure and the molecular mechanism underlying its genotoxic effects have... more
Common virus in early childhood linked to celiac disease in susceptible children  SCIENCE DAILY · 4 days
A common intestinal virus, enterovirus, in early childhood may be a trigger for later celiac disease in children at increased genetic risk of the... more
Researchers find 14 percent of sausages mislabelled in Canada, down from last study  PHYS.ORG · 4 days
Sausage mislabelling in Canada is down, according to a new University of Guelph DNA barcoding study. more
Scientists shed light on damaging cell effects linked to aging  NEWS MEDICAL · 4 days
Some of the damaging cell effects linked to aging could be prevented by manipulating tiny parts of cells, a study shows. more
New live-imaging technique reveals cellular repair crew plugging leaky biological barrier  PHYS.ORG · 4 days
Suppose you live in a brick house and notice cracks in the mortar that let in cold air, rain and insect pests. You might call a... more
High-speed surveillance in solar cells catches recombination red-handed  SCIENCE DAILY · 4 days
Using synchronized lasers pulses, researchers developed a new method of electrostatic force microscopy that can record movies with frames as fast as 300 nanoseconds. This is fast enough to watch electrons move... more
Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children  SCIENCE DAILY · 4 days
Progress reported on understanding why Hispanic children are more likely to develop acute lymphoblastic leukemia and to die of the... more
Controlling and visualizing receptor signals in neural cells with light  SCIENCE DAILY · 4 days
Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualized serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in... more
Orangutans make complex economic decisions about tool use  SCIENCE DAILY · 4 days
Flexible tool use is closely associated to higher mental processes such as the ability to plan actions. Now a group of cognitive biologists and comparative psychologists found out that the apes carefully... more
'Lack of cleaning' in brain cells is central to Alzheimer's disease  SCIENCE DAILY · 4 days
An international research team has created a better understanding of Alzheimer's. They have shown that the cleaning system of the brain cells, the so-called mitophagy, is... more
Platinum nanoparticles for selective treatment of liver cancer cells  SCIENCE DAILY · 4 days
Researchers recently demonstrated that platinum nanoparticles can be used to kill liver cancer cells with greater selectivity than existing cancer drugs. more
How proteins become embedded in a cell membrane  SCIENCE DAILY · 4 days
Many proteins with important biological functions are embedded in a biomembrane in the cells of humans and other living organisms. But how do they get in there in the first place? Researchers... more
Immunological scarring from celiac disease  SCIENCE DAILY · 4 days
Immune cells in the bowel of people who suffer with celiac disease are permanently replaced by a new subset of cells that promote inflammation, suggests a new study. more
Controlling and visualising receptor signals in neural cells with light  PHYS.ORG · 4 days
Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualised serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in... more
UN: Experts to develop oversight standards for gene editing  ABC NEWS · 4 days
The World Health Organization is convening a meeting next month to develop global standards for the governance of gene editing, after a Chinese researcher announced he had created the world's... more
Cell study sheds light on damage caused by aging  SCIENCE DAILY · 4 days
Some of the damaging cell effects linked to aging could be prevented by manipulating tiny parts of cells, a study shows. more
Tracking pollen with quantum dots  nanowerk · 4 days
A pollination biologist is using quantum dots to track the fate of individual pollen grains. This is breaking new ground in a field of research that has been hampered by the lack of a universal method to track. more
Tracking pollen with quantum dots  PHYS.ORG · 4 days
A pollination biologist from Stellenbosch University in South Africa is using quantum dots to track the fate of individual pollen grains. This is breaking new ground in a field of research that has been hampered by the lack... more
Researchers develop diagnostic tool for detecting cryptosporidium  PHYS.ORG · 4 days
A handheld 'tricorder' that can test for biological contamination in real-time has been the dream of science fiction fans for decades. And UBC Okanagan engineers say the technology is closer to science fact than... more
Skin wound regeneration with bioactive glass-gold nanoparticles ointment  PHYS.ORG · 4 days
Healing is a complex process in adult skin impairments, requiring collaborative biochemical processes for onsite repair. Diverse cell types (macrophages, leukocytes, mast cells) contribute to the associated phases of proliferation, migration, matrix... more
Biologist's research could lead to more resilient crops  PHYS.ORG · 4 days
UCLA biologist Steve Jacobsen's research has the potential to have a significant impact on the improvement of crops. more
Algae
Customizing the Cellular Microenvironment to Improve Physiological Relevance
NEWS MEDICAL
ESA’s Mars rover has a name – Rosalind Franklin
ESA
More nutritious, natural flavor, non-GMO 'orange corn' launches in US markets
PHYS.ORG
Aggregated social amoebae need physical contact rather than chemical signals for motivation
PHYS.ORG
Time-lapse microscopy helps reveal brake mechanism in Streptomyces lifecycle
PHYS.ORG
Research using atom probe tomography reveals chinks in iron crystals that can 'heal'
PHYS.ORG
Rhomboid enzymes warp space to break cellular speed limit
NEWS MEDICAL
New type of map connects the dots in cellular reprogramming
PHYS.ORG
Cloning monkeys for research puts humans on a slippery ethical slope
PHYS.ORG
'Light tweezers' can move, melt, and scatter mysterious biological 'icebergs'
PHYS.ORG
'Superbug gene' found in one of the most remote places on Earth
PHYS.ORG
How light-farming chloroplasts morph into defensive warriors
SCIENCE-NEWS
Cellular stress at the movies: Biochemists illuminate a key survival mechanism in cells
PHYS.ORG
You can't control what you can't find: Detecting invasive species while they're still scarce
PHYS.ORG
3D-printed soft mesh robots
SCIENCE DAILY
Lab-Scale Clarification of Mammalian Cell Cultures Expressing Recombinant Antibodies
NEWS MEDICAL
Researchers first to use CRISPR/Cas9 to control genetic inheritance in mice
PHYS.ORG
New method uses ultraviolet light to control fluid flow and organize particles
PHYS.ORG
Mechanical engineers develop process to 3-D print piezoelectric materials
PHYS.ORG
Seeding the Milky Way with life using 'Genesis missions'
PHYS.ORG
Fresh