Microbiology
Adults carrying Alzheimer's risk gene have harder time accessing recently acquired knowledge  NEWS MEDICAL · 5 hours
Adults carrying a gene associated with a higher risk of Alzheimer's disease had a harder time accessing recently acquired knowledge, even though they didn't... more
Exploiting mammalian low-complexity domains for liquid-liquid phase separation-driven underwater adhesive coatings  Science Magazine · 5 hours
Many biological materials form via liquid-liquid phase separation (LLPS), followed by maturation into a solid-like state. Here, using a biologically inspired assembly mechanism designed to recapitulate... more
Organ-on-e-chip: Three-dimensional self-rolled biosensor array for electrical interrogations of human electrogenic spheroids  Science Magazine · 5 hours
Cell-cell communication plays a pivotal role in coordination and function of biological systems. Three-dimensional (3D) spheroids provide venues to explore cellular communication for tissue... more
A wave of monocytes is recruited to replenish the long-term Langerhans cell network after immune injury  Science Magazine · 6 hours
A dense population of embryo-derived Langerhans cells (eLCs) is maintained within the sealed epidermis without contribution... more
Bioprinting complex living tissue in just a few seconds  PHYS.ORG · 7 hours
Tissue engineers create artificial organs and tissues that can be used to develop and test new drugs, repair damaged tissue and even replace entire organs in the human body. However,... more
Breath! Respiring microbes generate more energy  PHYS.ORG · 8 hours
How do cells generate and use energy? This question might seem simple, but the answer is far from simple. Furthermore, knowing how microbial cell factories consume energy and how proteins are allocated to do so is... more
Bioprinting complex living tissue in just a few seconds  nanowerk · 8 hours
Researchers have come up with an optical technique that takes just a few seconds to sculpt complex tissue shapes in a biocompatible hydrogel containing stem cells. The resulting tissue can... more
Frying oil consumption worsened colon cancer and colitis in mice, study shows  SCIENCE DAILY · 9 hours
Food scientists have shown that feeding frying oil to mice exaggerated colonic inflammation, enhanced tumor growth and worsened gut leakage, spreading bacteria or toxic... more
Bioprinting complex living tissue in just a few seconds  SCIENCE DAILY · 9 hours
Researchers have developed an extremely fast optical method for sculpting complex shapes in stem-cell-laden hydrogels and then vascularizing the resulting tissue. Their groundbreaking technique stands to change the field of... more
Experiments illuminate key component of plants' immune systems  SCIENCE DAILY · 10 hours
Biologists have shed new light on a crucial aspect of the plant immune response. Their discovery, revealing how plant resistance proteins trigger localized cell death, could lead to new strategies for engineering... more
Cell suicide could hold key for brain health and food security  SCIENCE DAILY · 10 hours
Research into the self-destruction of cells in humans and plants could lead to treatments for neurodegenerative brain diseases and the development of disease-resistant plants. A study... more
Larval Bees are Omnivores, Shows New Study  SCI-NEWS.COM · 10 hours
Pollen-borne microbes represent an important protein source for larval bees, according to new research. Of the more than 20,000 species of bees... more
Biomaterials smarten up with CRISPR  SCIENCE DAILY · 10 hours
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide... more
Map of malaria behavior set to revolutionize research  SCIENCE DAILY · 10 hours
The first detailed map of individual malaria parasite behavior across each stage of its complicated life cycle has been created by scientists. Researchers used advanced single-cell technology to isolate individual parasites and... more
UN: Ebola outbreak in Congo has killed nearly 2,000 people  ABC NEWS · 10 hours
The World Health Organization's emergencies chief said the ongoing Ebola outbreak in Congo is approaching a "stark" milestone with nearly 2,000 people killed by the virus in the... more
Researchers find a way to stop lung damage due to the body's immune response  SCIENCE DAILY · 10 hours
Researchers have discovered a new way to stop harmful inflammation in the lungs due to sepsis and injury. They found... more
Nano-thermometer takes temperature inside cells  SCIENCE DAILY · 11 hours
Scientists have developed a nano-thermometer able to take temperatures inside cells. The technique takes advantage of the fluorescent properties of a modified molecular rotor and the viscosity of the cell. more
Scientists find longevity biomarkers  PHYS.ORG · 11 hours
An international group of scientists studied the effects of 17 lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal Cell Metabolism. more
A new method for quantifying crystal semiconductor efficiency  PHYS.ORG · 11 hours
Japanese scientists have found a new way to detect the efficiency of crystal semiconductors. For the first time ever, the team used a specific kind of photoluminescence spectroscopy, a way to detect... more
Key areas of measles virus polymerase to target for antiviral drug development  SCIENCE DAILY · 11 hours
Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be... more
Using CRISPR to program gels with new functions  PHYS.ORG · 12 hours
The CRISPR genome-editing system is best-known for its potential to correct disease-causing mutations and add new genes into living cells. Now, a team from MIT and Harvard University has deployed CRISPR for... more
Living Cells Can Record and Track Genomic Events with New “Designer Cell” Computer Technology  NEWS MEDICAL · 12 hours
Published in Molecular Cell, researchers at Massachusetts Institute of Technology (MIT) have developed a new technology that uses DNA to... more
New approach to detection reveals unreported Zika outbreak in 2017  NEWS MEDICAL · 13 hours
Public health experts in the US have discovered that the Zika virus may still be spreading in the Americas, despite case reporting having approached close to zero. more
UQ researchers discover how our genes, environment influence BMI and height  NEWS MEDICAL · 15 hours
Environmental conditions influence our body mass index by increasing or decreasing the effect of inherited genetic variations, University of Queensland researchers have discovered. more
Super-powered immune cells to attack tumors  NEWS MEDICAL · 16 hours
The phase 1 clinical trial will test the feasibility and safety of CAR-T cells - genetically modified white blood cells harvested from a patient's own blood with the unique ability to directly attack and kill cancers... more
Researchers create synthetic biologic system to deliver medicine, treat wounds for soldiers  NEWS MEDICAL · 16 hours
For the first time, scientists built a synthetic biologic system with compartments like real cells. This Army project at the University of Massachusetts Amherst... more
Harnessing power of CRISPR to control behavior of DNA-responsive materials  NEWS MEDICAL · 17 hours
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies... more
Combination therapy for rheumatoid arthritis may lead to higher remission rates  NEWS MEDICAL · 21 hours
Researchers at the University of North Carolina Chapel Hill and RTI International, a nonprofit research institute, recently found that patients with early rheumatoid arthritis (RA) may... more
Medical News Today: Study links insomnia genes to heart disease, stroke risk  MNT · 23 hours
New research using a genetic analysis called Mendelian randomization links insomnia genes to a greater risk of heart disease and stroke. more
Here's how early humans evaded immunodeficiency viruses  SCIENCE DAILY · 1 day
The cryoEM structure of a simian immunodeficiency virus protein bound to primate proteins shows how a mutation in early humans allowed our ancestors to escape infection while monkeys and apes did not. SIV's Nef... more
Scientists In New York Are Trying To Edit The DNA In Human Sperm  NPR · 1 day
NPR got exclusive access to the only lab known to be trying to edit the DNA in human sperm, which raises all... more
Genes tell the story of how the Asian tiger mosquito spread  SCIENCE DAILY · 1 day
Over the last 40 years, the Asian tiger mosquito, Aedes albopictus, has invaded every continent thanks to the transportation of its eggs via human trade and... more
Yet another way dogs help the military: aeromedical patient evacuations  SCIENCE DAILY · 1 day
Animal-assisted therapy has many benefits in health care. Yet, its biological and psychosocial effects in the military are unknown, especially for injured, airlifted patients. Researchers teamed up with... more
Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge  SCIENCE DAILY · 1 day
Adults carrying a gene associated with a higher risk of Alzheimer's disease had a harder time accessing recently acquired knowledge, even though they didn't show any... more
Structure of protein nano turbine revealed  SCIENCE DAILY · 1 day
Scientists have determined the first structure of a cell's rotary engine using state-of-art microscopy. more
Memory T cells shelter in bone marrow, boosting immunity in mice with restricted diets  SCIENCE DAILY · 1 day
Even when taking in fewer calories and nutrients, humans and other mammals usually remain protected against infectious diseases they have... more
New tool mines scientific texts for fusion protein facts  SCIENCE DAILY · 1 day
A new computational tool called ProtFus screens scientific literature to validate predictions about the activity of fusion proteins -- proteins encoded by the joining of two genes that previously encoded... more
Slow electrons to fight cancer  NEWS MEDICAL · 1 day
Ion beams are often used today in cancer treatment: this involves electrically charged atoms being fired at the tumor to destroy cancer cells. more
Nano-thermometer takes temperature inside cells  nanowerk · 1 day
Chemists use fluorescence of molecular motors to sense conditions. more
Computer model could be used to quickly evaluate new drugs for sickle cell disease  NEWS MEDICAL · 1 day
A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become... more
Research team develops microbiome-based index for assessing skin health  NEWS MEDICAL · 1 day
Microbiomes aren't just for understanding and modulating gut health - skin, our largest organ, hosts a vibrant and complex microbiome that can provide health insights. An international research team has... more
Structure of protein nano turbine revealed  nanowerk · 1 day
Scientists determine the first structure of a cell's rotary engine using state-of-art microscopy. more
Fasting reduces inflammation and improves chronic inflammatory diseases, study finds  NEWS MEDICAL · 1 day
Fasting regimens have gained public and scientific interest in recent years, but fasting shouldn't be dismissed as a fad. In a study published in Cell, Mount Sinai researchers... more
Here's Why Drugs That Work So Well in Mouse Brains Often Fail Miserably in Humans  LIVE SCIENCE · 1 day
Mice and humans have the same kinds of brain cells and wiring. But the similarities may stop there. more
New model developed to optimize and personalize radiotherapy for cancer patients  NEWS MEDICAL · 1 day
A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with... more
Ludwig study uncovers novel vulnerability in MYC-driven cancers  NEWS MEDICAL · 1 day
A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the... more
Virginia Tech professor wins NSF grant to study biofilm formation in bacteria  NEWS MEDICAL · 1 day
Should I stay or should I go? This is a common question people ask themselves in their journey through life, but bacteria are also... more
Phase-change heterostructure enables ultralow noise and drift for memory operation  Science Magazine · 1 day
Artificial intelligence and other data-intensive applications have escalated the demand for data storage and processing. New computing devices, e.g., phase-change random access memory (PCRAM) based neuro-inspired devices, are... more
N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication  Science Magazine · 1 day
Host cell metabolism can be modulated by viral infection, affecting viral survival or clearance. The cellular metabolism rewiring mediated by N6-methyladenosine (m6A) modification in virus-host interaction remains largely unknown. Here... more
NAD+ cleavage activity by animal and plant TIR domains in cell death pathways  Science Magazine · 1 day
SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of nicotinamide adenine dinucleotide in its oxidized form (NAD+) during... more
Programmable CRISPR-responsive smart materials  Science Magazine · 1 day
Stimuli-responsive materials activated by biological signals play an increasingly important role in biotechnology applications. We exploit the programmability of CRISPR-associated nucleases to actuate hydrogels containing DNA as a structural element or as an anchor for pendant groups. After activation by... more
The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle  Science Magazine · 1 day
Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We... more
Persistence of neuronal representations through time and damage in the hippocampus  Science Magazine · 1 day
How do neurons encode long-term memories? Bilateral imaging of neuronal activity in the mouse hippocampus reveals that, from one day to the next, ~40% of neurons... more
Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation  Science Magazine · 1 day
Membraneless organelles involved in RNA processing are biomolecular condensates assembled by phase separation. Despite the important role of intrinsically disordered protein regions... more
Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase  Science Magazine · 1 day
V (vacuolar)/A (archaeal)-type adenosine triphosphatases (ATPases), found in archaea and eubacteria, couple ATP hydrolysis or synthesis to proton translocation across the plasma membrane using the rotary-catalysis... more
TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death  Science Magazine · 1 day
Plant nucleotide-binding leucine-rich repeat (NLR) immune receptors activate cell death and confer disease resistance by unknown mechanisms. We demonstrate that plant Toll/interleukin-1... more
The global soil community and its influence on biogeochemistry  Science Magazine · 1 day
Soil organisms represent the most biologically diverse community on land and govern the turnover of the largest organic matter pool in the terrestrial biosphere. The highly complex nature of these... more
New tool mines scientific texts for fusion protein facts  PHYS.ORG · 1 day
A new computational tool called ProtFus screens scientific literature to validate predictions about the activity of fusion proteins—proteins encoded by the joining of two genes that previously encoded two separate... more
Biomaterials smarten up with CRISPR  PHYS.ORG · 1 day
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide... more
Map of malaria behavior set to revolutionize research  PHYS.ORG · 1 day
The first detailed map of individual malaria parasite behaviour across each stage of its complicated life cycle has been created by scientists. Researchers at the Wellcome Sanger Institute and their collaborators used... more
Structure of protein nanoturbine revealed  PHYS.ORG · 1 day
Cells rely on protein complexes known as ATP synthases or ATPases for their energy needs. Adenosine triphosphate (ATP) molecules power most of the processes sustaining life. Structural biologist Professor Leonid Sazanov and his research group from the Institute... more
Cell suicide could hold key for brain health and food security  PHYS.ORG · 1 day
Research into the self-destruction of cells in humans and plants could lead to treatments for neurodegenerative brain diseases and the development of disease-resistant plants. more
Experiments illuminate key component of plants' immune systems  PHYS.ORG · 1 day
Plants, like humans and animals, have over millions of years evolved complex immune systems that fend off invading pathogens. But unlike many animals, plants lack adaptive immunity conferred by antibodies. This means... more
Tracing the evolution of vision in fruit flies  PHYS.ORG · 1 day
The function of the visual photopigment rhodopsin and its action in the retina to facilitate vision is well understood. However, there remain questions about other biological functions of this family of proteins... more
New method classifies brain cells based on electrical signals  MIT · 1 day
Making electrophysiology more informative, team shows how to distinguish four classes of cells by spike waveform. more
Using CRISPR to program gels with new functions  MIT · 1 day
Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices. more
Adaptation to life inside cattle may be driving E. coli to develop harmful features  PHYS.ORG · 1 day
A large-scale study of the genetic differences and similarities among E. coli bacteria from cattle and humans indicates that features... more
Scientists successfully innoculate, grow crops in salt-damaged soil  SCIENCE DAILY · 1 day
Researchers may have found a way to reverse falling crop yields caused by increasingly salty farmlands throughout the world. Scientists have used bacteria found in the roots of salt-tolerant plants to successfully... more
Tracing the evolution of vision  SCIENCE DAILY · 1 day
The function of the visual photopigment rhodopsin and its action in the retina to facilitate vision is well understood. However, there remain questions about other biological functions of this family of proteins (opsins) and this has ramifications for... more
Genetic diversity couldn't save Darwin's finches  SCIENCE DAILY · 1 day
Researchers found that Charles Darwin's famous finches defy what has long been considered a key to evolutionary success: genetic diversity. The study of the finches of the Galapagos Islands could change the way conservation biologists think... more
Comparison of three similar frontline breast cancer drugs reveals important differences  SCIENCE DAILY · 1 day
First head-to-head comparison of CDK4/6 inhibitors in cell line and animal models of breast cancer reveals important differences, including one drug that exhibits unique, potentially advantageous... more
An unreported Zika outbreak in 2017 detected through travel surveillance and genetics  SCIENCE DAILY · 1 day
By sequencing virus genomes from infected travelers, analyzing travel patterns and mosquito modeling, researchers unearthed a spike in Zika cases from travelers returning from... more
High-precision technique stores cellular 'memory' in DNA  SCIENCE DAILY · 1 day
Researchers have created a technology called DOMINO to store complex 'memories' in the DNA of living cells, including human cells. This memory storage capacity can form the foundation of complex circuits that trigger a... more
Scorpion toxin that targets 'wasabi receptor' may help solve mystery of chronic pain  SCIENCE DAILY · 1 day
Researchers have discovered a scorpion toxin that targets the 'wasabi receptor,' a chemical-sensing protein found in nerve cells that's responsible for the... more
Certain metabolites linked to stem cell function in the intestine  SCIENCE DAILY · 1 day
Researchers have found that high levels of ketone bodies, molecules produced by the breakdown of fat, help the intestine to maintain a functional stem cell pool, which are... more
Materials scientists build a synthetic system with compartments like real cells  SCIENCE DAILY · 1 day
Polymer chemists and materials scientists have achieved some notable advances that mimic Nature, but one of the most common and practical features of cells has so... more
Early life on Earth limited by enzyme  SCIENCE DAILY · 1 day
A single enzyme found in early single-cell life forms could explain why oxygen levels in the atmosphere remained low for two billion years during the Proterozoic eon, preventing life colonizing land. more
Study links certain metabolites to stem cell function in the intestine  MIT · 1 day
Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue. more
Study started for bacteria-free space missions  ESA · 1 day
Bacteria grow everywhere, including inside the International Space Station. That is why ESA has selected the Luxembourg Institute of Science and Technology (LIST) to... more
Researchers reveal plant defense toolkit and insights for fighting crop diseases  PHYS.ORG · 1 day
At an unprecedented scale, researchers have now cataloged the array of surveillance tools that plants use to detect disease-causing microbes across an entire species. Representing a... more
Materials scientists build a synthetic system with compartments like real cells  PHYS.ORG · 1 day
Polymer chemists and materials scientists have achieved some notable advances that mimic Nature, but one of the most common and practical features of cells has so... more
Atacama Desert microbes may hold clues to life on Mars  PHYS.ORG · 1 day
Microbial life on Mars may potentially be transported across the planet on dust particles carried by wind, according to a study conducted in the Atacama Desert in North... more
High-precision technique stores cellular 'memory' in DNA  PHYS.ORG · 1 day
Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells. more
Early life on Earth limited by enzyme  PHYS.ORG · 1 day
The enzyme-nitrogenase-can be traced back to the universal common ancestor of all cells more than four billion years ago. more
Computer model could help test new sickle cell drugs  SCIENCE DAILY · 1 day
A new computer model that captures the dynamics of the red blood cell sickling process could help in evaluating drugs for treating sickle cell disease. more
E-cigs can trigger same lung changes seen in smokers, emphysema  SCIENCE DAILY · 1 day
Scientists found that the lungs of vapers -- like the lungs of smokers -- have elevated levels of protease enzymes, a condition known to cause emphysema in smokers.... more
Slow electrons to combat cancer  SCIENCE DAILY · 1 day
Slow electons can be used to destroy cancer cells - but how exactly this happens has not been well understood. Now scientists have been able to demonstrate that a previously little-observed effect actually plays a pivotal role: Due... more
Washing laundry may be an underappreciated source of microplastic pollution  PHYS.ORG · 1 day
Concerns over plastic in the ocean are growing in recent years. About 2.41 million tons of plastic waste enter the oceans every year, including approximately 15,000 plastic bags... more
Bacterial sex drives evolution of microbes to conquer and colonize the gut  PHYS.ORG · 1 day
Bacterial sex drives evolution of microbes to conquer and colonize the gut. This discovery constitutes a paradigm shift and opens the possibility to design... more
Slow electrons to combat cancer  PHYS.ORG · 1 day
Ion beams are often used today in cancer treatment: this involves electrically charged atoms being fired at the tumour to destroy cancer cells. Although, it's not actually the ions themselves that cause the decisive damage. When ions penetrate... more
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