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Medical News Today: Hepatitis C outside the body and other virus facts
MNT In this article, we take a look at how long the hepatitis C virus can survive outside the body, and how this impacts on... 13 hours
Study prompts new ideas on cancers’ origins
SCIENCE DAILY Cancer therapies often target cells that grow and divide rapidly, such as stem cells, but in studying how stomach cancers occur, researchers found that even when the stomach isn't able to make stem cells,... 1 day
Genetic study uncovers fungal sex secrets, which shed light on candidiasis
SCIENCE DAILY A new genetic analysis of fungal yeast infections (candidiasis) from around the world has revealed surprising secrets about how these microbes reproduce and cause disease, according... 2 days
Study reveals biology behind why muscle stem cells respond differently to aging or injury
NEWS MEDICAL A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute describes the biology behind why muscle stem... 2 days
Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells
NEWS MEDICAL A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells... 2 days
Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors
NEWS MEDICAL CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings... 2 days
Distinct human mutations can alter the effect of medicine
SCIENCE DAILY About one third of all medicine binds to the same type of receptor in the human body. An estimated three percent of the population have receptors of this type that... 2 days
Genetic instructions from mom set the pattern for embryonic development
SCIENCE DAILY A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from... 2 days
‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins
NEWS MEDICAL When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they... 2 days
Scientists advance knowledge of plant reproduction
SCIENCE DAILY Two groups of plant molecular biologists have long studied how pollen tubes and pistils, the male and female parts of flowers, communicate to achieve fertilization in plants. Now they report that they have identified a pair... 2 days
What does hair loss have to teach us about cancer metastasis?
SCIENCE DAILY Researchers have identified a signaling pathway regulating cell migration and metastasis. Unexpected hair loss in a preclinical model helped them to identify the pathway. When cells... 2 days
Researchers track muscle stem cell dynamics in response to injury and aging
SCIENCE DAILY A new study describes the biology behind why muscle stem cells respond differently to aging or injury. The findings have important implications for the... 2 days
Artificial intelligence used to identify bacteria quickly and accurately
SCIENCE DAILY Microscopes enhanced with artificial intelligence (AI) could help clinical microbiologists diagnose potentially deadly blood infections and improve patients' odds of survival, according to microbiologists. 2 days
Nanodiscs catch misfolding proteins red-handed
SCIENCE DAILY When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level. 2 days
GAPs in early life facilitate immune tolerance
Science Magazine Goblet cells deliver microbial antigens to generate regulatory T cells before and during weaning to induce long-term tolerance to symbionts. 2 days
Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria
Science Magazine We have a mutually beneficial relationship with the trillions of microorganisms inhabiting our gastrointestinal tract. However, maintaining this relationship requires... 2 days
Reactivity of prehydrated electrons toward nucleobases and nucleotides in aqueous solution
Science Magazine DNA damage induced via dissociative attachment by low-energy electrons (0 to 20 eV) is well studied in both gas and condensed phases. However, the reactivity of... 2 days
Medical News Today: Breast cancer: These gene variations may shorten young women's survival
MNT New research finds that young women with early-onset breast cancer possess variations in a specific gene that might affect their survival. 2 days
3-D nanoscale imaging made possible
SCIENCE DAILY Imaging at the nanoscale is important to a plethora of modern applications in materials science, physics, biology, medicine and other fields. Limitations of current techniques are, e.g. their resolution, imaging speed or the inability to look behind opaque... 2 days
Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup
NEWS MEDICAL Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the... 2 days
Genetic instructions from mom set the pattern for embryonic development
PHYS.ORG A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from... 2 days
Extracellular vesicles can be used to effectively delay progression of kidney damage
NEWS MEDICAL Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be... 2 days
Medical News Today: Hemophilia cure? Gene therapy trial shows dramatic results
MNT A year after gene therapy treatment, people with hemophilia A are showing normal levels of clotting factor and big reductions in bleeding. 2 days
Mechanism identified of impaired dendritic cell function that weakens response to cancer
SCIENCE DAILY The mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their... 2 days
Nanoparticles as a solution against antibiotic resistance?
SCIENCE DAILY Scientists have succeeded in developing an efficient method to treat mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination. First of all, the active particles need to have a certain... 2 days
Cancer immunotherapy may work better in patients with specific genes
SCIENCE DAILY Investigators have been trying to understand why and have recently found how an individual's own genes can play a role in the response to the immunotherapy drugs. 3 days
Why the idea that the English have a common Anglo-Saxon origin is a myth
PHYS.ORG The idea that there is a common Anglo-Saxon ancestry based on biology is gaining currency among some right-wing and religious... 3 days
Rare gene mutation gives rise to low sensitivity to pain
NEWS MEDICAL Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by... 3 days
Potato blight's chemical attack mechanism explained
PHYS.ORG A team of international researchers headed by scientists from the University of Tübingen has deciphered the workings of a cytolytic toxin, which is produced by some of the world's most devastating crop diseases. The Cytolysin is... 3 days
3-D nanoscale imaging made possible
PHYS.ORG Imaging at the nanoscale is important to a plethora of modern applications in materials science, physics, biology, medicine and other fields. Limitations of current techniques are, e.g. their resolution, imaging speed or the inability to look behind opaque... 3 days
Researchers examine link between tumor mutational burden and response to immune checkpoint therapy
NEWS MEDICAL Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome. 3 days
Epigenetic rheostat uncovers how gene regulation is inherited and maintained
PHYS.ORG While our genome contains a vast repertoire of genes that are responsible for virtually all of the cellular and developmental processes life requires, it is the complex dance... 3 days
Video: Insect biology students learn art of bug-based dyes
PHYS.ORG VIDEO Cochineal bugs use a coloring as a defense mechanism, but humans have learned to use it to dye fabric. Before the advent of synthetic dyes, all dyes were made from insects... 3 days
Nanoparticles as a possible solution to antibiotic resistance
PHYS.ORG Around one in 3,300 children in Germany is born with mucoviscidosis. A characteristic of this illness is that one channel albumen on the cell surface is disturbed by mutations. Thus, the amount... 3 days
New research linking cancer-inhibiting proteins to cell antennae
PHYS.ORG Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts,... 3 days
Medical News Today: Need more sleep than most people? Blame your genes
MNT Do you need 12 hours of sleep per day to function? Or is 2 hours per night enough for you? A new study investigates... 3 days
Study provides insights into molecular mechanisms regulating cellular fate of SCCs
NEWS MEDICAL Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas. 3 days
Scientists create atomic scale map that tracks how brain signals connect to neurons
NEWS MEDICAL Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to... 3 days
Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer
NEWS MEDICAL A new study led by scientists at the University of Southampton has found that inherited variation... 3 days
Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun
NEWS MEDICAL A fusion gene is a single composite gene that is the result of the combination of two formerly... 3 days
Bioluminescent succinate detection monitors dioxygenases and JMJC demethylases
PHYS.ORG A new (and freely available) original research article published ahead-of-print at SLAS Discovery Online describes a new methodology that enables the investigation of a large number of structurally conserved enzymes belonging to... 3 days
Charting how brain signals connect to neurons
SCIENCE DAILY Scientists have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic... 3 days
How defeating THOR could bring a hammer down on cancer
SCIENCE DAILY Researchers have uncovered a novel gene they named THOR. It's a highly conserved long non-coding RNA that plays a role in cancer development. Knocking it out can halt... 3 days
Scientists unravel mystery of how immune cells remember infections decades later
NEWS MEDICAL A perplexing question in immunology has been, how do immune cells remember an infection or a vaccination so that they can spring into action decades later?... 3 days
Bioengineers imagine the future of vaccines and immunotherapy
SCIENCE DAILY In the not-too-distant future, nanoparticles delivered to a cancer patient's immune cells might teach the cells to destroy tumors. A flu vaccine might look and feel like applying a small, round bandage... 3 days
To sleep or not: Researchers explore complex genetic network behind sleep duration
SCIENCE DAILY Scientists have identified differences in a group of genes they say might help explain why some people need a lot more sleep -- and... 3 days
Muscle paralysis may promote breakdown of bones
NEWS MEDICAL Muscle paralysis rapidly causes inflammation in nearby bone marrow, which may promote the formation of large cells that break down bone, a new study finds. 3 days
BigH1: The key histone for male fertility
SCIENCE DAILY Researchers have unraveled the role of the histone BigH1 in the development of male sex cells from stem cells. Their study, which was performed in Drosophila melanogaster, paves the way to a greater understanding... 3 days
Experience of reflex walking refines perception of biological motion during early infancy
NEWS MEDICAL Ten-week-old babies can learn from practicing walking months before they begin walking themselves say researchers. 3 days
Researchers identify previously unknown functions of natural killer cells in the womb
NEWS MEDICAL For the first time the functions of natural killer cells in the womb have been identified. Researchers at the University of Warwick and University... 3 days
Scientists develop new approach to identify important undiscovered functions of proteins
PHYS.ORG In the bustling setting of the cell, proteins encounter each other by the thousands. Despite the hubbub, each one manages to selectively interact with just the... 3 days
Researchers discover how cells remember infections decades later
PHYS.ORG A perplexing question in immunology has been, how do immune cells remember an infection or a vaccination so that they can spring into action decades later? Research led by scientists at the... 3 days
Spaghetti-like, DNA 'noodle origami' the new shape of things to come for nanotechnology
SCIENCE DAILY Scientists have invented a major new advance in DNA nanotechnology. Dubbed 'single-stranded origami,' their new strategy uses one long, thin noodle-like strand... 3 days
Womb natural killer cell discovery could lead to screening for miscarriage risk
SCIENCE DAILY For the first time the functions of natural killer cells in the womb have been identified. Researchers have discovered the role that they play... 3 days
Tracking planned experiments online could spot ways to improve animal testing
PHYS.ORG An online database of study summaries could be systematically evaluated to uncover new information about animal testing, including potential targets for efforts to minimize harm to... 3 days
Researchers identify a pair of receptors essential to male-female plant communications
PHYS.ORG Two groups of plant molecular biologists, at the University of Massachusetts Amherst and Peking University, China, have long studied how pollen tubes and pistils, the male... 3 days
To sleep or not: Researchers explore complex genetic network behind sleep duration
PHYS.ORG Scientists have identified differences in a group of genes they say might help explain why some people need a lot more sleep—and others less—than... 3 days
Monkeys infected by mosquito bites further Zika virus research
SCIENCE DAILY Monkeys who catch Zika virus through bites from infected mosquitoes develop infections that look like human Zika cases, and may help researchers understand the many ways Zika can be transmitted. 3 days
Arabidopsis pollen tube integrity and sperm release are regulated by RALF-mediated signaling
Science Magazine In flowering plants, fertilization requires complex cell-to-cell communication events between the pollen tube and the female reproductive tissues, which are controlled by extracellular signaling... 3 days
RALF4/19 peptides interact with LRX proteins to control pollen tube growth in Arabidopsis
Science Magazine The communication of changes in the extracellular matrix to the interior of the cell is crucial for a cell’s function. The extracellular... 3 days
The ER membrane protein complex is a transmembrane domain insertase
Science Magazine Insertion of proteins into membranes is an essential cellular process. The extensive biophysical and topological diversity of membrane proteins necessitates multiple insertion pathways that remain incompletely defined. Here,... 3 days
Single-stranded DNA and RNA origami
Science Magazine Self-folding of an information-carrying polymer into a defined structure is foundational to biology and offers attractive potential as a synthetic strategy. Although multicomponent self-assembly has produced complex synthetic nanostructures, unimolecular folding has seen limited progress. We describe a... 3 days
Bacteria go the distance in cancer
Science Magazine 3 days
Eudicot plant-specific sphingolipids determine host selectivity of microbial NLP cytolysins
Science Magazine Necrosis and ethylene-inducing peptide 1–like (NLP) proteins constitute a superfamily of proteins produced by plant pathogenic bacteria, fungi, and oomycetes. Many NLPs are cytotoxins that facilitate microbial infection... 3 days
Structural basis of membrane disruption and cellular toxicity by {alpha}-synuclein oligomers
Science Magazine Oligomeric species populated during the aggregation process of α-synuclein have been linked to neuronal impairment in Parkinson’s disease and related neurodegenerative disorders. By using solution and... 3 days
Enzyme-free nucleic acid dynamical systems
Science Magazine Chemistries exhibiting complex dynamics—from inorganic oscillators to gene regulatory networks—have been long known but either cannot be reprogrammed at will or rely on the sophisticated enzyme chemistry underlying the central dogma. Can simpler molecular mechanisms, designed from scratch,... 3 days
What keeps stem cells in their undifferentiated state?
SCIENCE DAILY A special cluster of proteins helps unwind DNA during cell division and plays a key role in keeping stem cells in their immature state, scientists have discovered. This study also points to... 3 days
Medical News Today: Silencing 'junk' gene could halt tumor growth
MNT Researchers have found that a gene they call THOR produces a long, non-coding RNA that has a role in cancer, and whose silencing stops tumor growth. 3 days
Researchers taking optical device out of the lab and into the clinic to detect cancer at its earliest stages
PHYS.ORG In a paper published in Nature Scientific Reports, a team... 3 days
Synthetic protein packages its own genetic material and evolves
SCIENCE DAILY Scientists have created computationally designed protein assemblies, that display some functions normally associated with living things, in the search for ways to transport therapeutic cargo into specific types of cells... 3 days
Sumatran rhinos never recovered from losses during the Pleistocene, genome evidence shows
PHYS.ORG The Sumatran rhinoceros (Dicerorhinus sumatrensis) is one of the most threatened mammals on earth. By 2011, only about 200 of the rhinos were thought... 3 days
Frequent sun exposure may cue gene fusion found in skin cancer
SCIENCE DAILY Researchers have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to... 3 days
Ancient genetic mutation helps explain origin of some human organs
SCIENCE DAILY A genetic mutation that occurred over 700 million years ago may have contributed to the development of certain organs in human beings and other vertebrates. This change, a... 3 days
Hydrogen production: protein environment makes catalyst efficient
SCIENCE DAILY The interaction of protein shell and active center in hydrogen-producing enzymes is crucial for the efficiency of biocatalysts. A team specifically analyzed the role of hydrogen bonds in certain enzymes from green algae, the... 3 days
DNA: Supercoiling pushes molecular handcuffs along chromatin fibres
SCIENCE DAILY As it squeezes down the chromatin fiber, the cohesin protein complex extrudes a growing loop of DNA -- a bit like the quick-lacing system of trail-running shoes. But what is powering the... 3 days
How a gene mutation could help to treat chronic pain
MNT Researchers suggest that a rare gene mutation that causes insensitivity to pain could be utilized to uncover new treatments for chronic pain. 3 days
Mosquito-infected monkeys may provide better understanding of Zika transmission routes
NEWS MEDICAL Monkeys who catch Zika virus through bites from infected mosquitoes develop infections that look like human Zika cases, and may help researchers understand the many ways Zika can... 3 days
Medical News Today: How a gene mutation could help to treat chronic pain
MNT Researchers suggest that a rare gene mutation that causes insensitivity to pain could be utilized to uncover new treatments for chronic pain. 3 days
Studies reveal possibility for memory T cells to serve a dual purpose
NEWS MEDICAL Scientists of two new complementary studies researching mice and humans claim that they have the strongest evidence yet that memory T cells responsible for... 3 days
New bird species named for Harvard 'father of biodiversity'
PHYS.ORG Here's something to tweet about: A new species of bird has been named for a retired Harvard biologist known as "the father of biodiversity." 3 days
Tracing a plant's steps: Following seed dispersal using chloroplast DNA
PHYS.ORG Plants spread their seeds across the landscape to colonize new areas, but it's difficult and expensive for biologists to trace their movements. Now, researchers at Portland State University... 3 days
New ultra-thin diamond membrane is a radiobiologist's best friend
SCIENCE DAILY Measuring dosage of radiation can be challenging, especially when working with low-energy protons, but researchers have now developed an ultra-thin diamond membrane that can measure the number of protons in... 3 days
Bacterial control mechanism for adjusting to changing conditions
SCIENCE DAILY A fundamental prerequisite for life on earth is the ability of living organisms to adapt to changing environmental conditions. Physicists have now determined that the regulation mechanisms used by bacteria to adapt... 4 days
Genetic mutation explains the origin of some human organs
PHYS.ORG A neutral genetic mutation—a fluke in the evolutionary process that had no apparent biological purpose—that appeared over 700 million years ago in biological evolution could help explain the origin of... 4 days
Supercoiling pushes molecular handcuffs along chromatin fibres
PHYS.ORG Gene regulation relies on complex structural arrangements and processes at the molecular level. One of them, called 'chromatin loop extrusion', strikingly resembles the quick-lacing system of some trail running shoes: as the buckle is... 4 days
Groundbreaking gene therapy trial set to cure hemophilia
SCIENCE DAILY A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial. 4 days
A new way to deliver mRNA genomes: Nucleocapsids with evolutionary properties
PHYS.ORG (Phys.org)—A team of researchers at the University of Washington has created microscopic assemblies for packaging genetic material that they call synthetic nucleocapsids. The team hopes the... 4 days
Fungus relies on bacteria to regulate key components of its reproductive machinery
PHYS.ORG To better understand how beneficial organisms (symbionts) are transmitted between host generations, researchers investigated the role of bacterial that lives within its host (endosymbionts)... 4 days
Designer proteins that package genetic material could help deliver gene therapy
PHYS.ORG If you've ever bought a new iPhone, you've experienced good packaging. 4 days
In a tally of nerve cells in the outer wrinkles of the brain, a dog wins
SCIENCE-NEWS Among some carnivores, golden retrievers rate at the top for numbers of nerve cells, study finds. 4 days
Protein environment makes catalyst efficient for hydrogen production
PHYS.ORG The interaction of protein shell and active centre in hydrogen-producing enzymes is crucial for the efficiency of biocatalysts. A team from Ruhr-Universität Bochum and the Max Planck Institute for Chemical Energy Conversion... 4 days
Antarctic Microbes Can Survive on Air Alone
LIVE SCIENCE With little sunlight and few soil nutrients, Antarctic microbes have evolved to be creative. 4 days
Fully screen-printed monoPoly silicon solar cell technology
PHYS.ORG The Solar Energy Research Institute of Singapore (SERIS) at the National University of Singapore (NUS) has reached a new cell efficiency milestone in the development of its low-cost screen-printed bifacial monoPoly silicon solar cell... 4 days
Cells sense and explore their environments
PHYS.ORG The process through which cells are able to sense their environment is regulated by force detection. This is the main conclusion of a study published in the journal Nature, led by the team of Pere Roca-Cusachs,... 4 days
New blood test accurately forecasts advanced heart failure patients’ survival after surgery
NEWS MEDICAL An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for... 4 days
BigH1—the key histone for male fertility
PHYS.ORG Researchers in the Chromatin Structure and Function Lab at the Institute for Research in Biomedicine (IRB Barcelona) have identified the histone BigH1 as a key protein in stem cell differentiation to male sex cells. Histones are... 4 days
Bacterial control mechanism for adjusting to changing conditions
PHYS.ORG A fundamental prerequisite for life on earth is the ability of living organisms to adapt to changing environmental conditions. Physicists at the Technical University of Munich (TUM) and the University of California... 4 days
Study: Living Lyme disease bacteria found months after antibiotic treatment
NEWS MEDICAL Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the US, today announced results of two papers published in the peer-reviewed journals PLOS ONE and... 4 days
Groundbreaking gene therapy trial brings cure for hemophilia closer
NEWS MEDICAL A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial led by the NHS in London. 4 days
Video: Insect biology students learn art of bug-based dyes
PHYS.ORG
Searching for the CRISPR Swiss-army knife
PHYS.ORG
Building 3-D models of molecules with RealityConvert
PHYS.ORG
Could Probiotics Protect Kids From A Downside Of Antibiotics?
NPR
Can data save dolphins? How scientists are using NASA data to study link between solar storms and animal beachings
PHYS.ORG
In The U.S., Flu Season Could Be Unusually Harsh This Year
NPR
Scientists modify CRISPR to epigenetically treat diabetes, kidney disease, muscular dystrophy
PHYS.ORG
Biodiversity surprises at bubbly deep-sea cold seeps along Cascadia fault
PHYS.ORG
Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis
NEWS MEDICAL