Genetics
Coastal pollution reduces genetic diversity of corals, reef resilience  PHYS.ORG · 4 hours
A new study by researchers at the University of Hawai'i at Mānoa School of Ocean and Earth Science and Technology (SOEST) found that human-induced environmental stressors have a large effect... more
Turning cells into computers with protein logic gates  nanowerk · 4 hours
Biochemists have created 'smart' proteins that function inside human cells by turning genes on and off. more
NYC residents should cover face when in public, mayor says  ABC NEWS · 13 hours
New York City Mayor Bill De Blasio asked New Yorkers to wear a face covering when they go outside and will be near other people more
NYC residents to cover face when going out  ABC NEWS · 14 hours
New York City Mayor Bill De Blasio asked New Yorkers to wear a face covering when they go outside and will be near other people more
Homo sapiens Interbred with Various Neanderthal Populations, Study Says  SCI-NEWS.COM · 16 hours
Modern humans in Eurasia carry genetic material inherited from Altai Neanderthals, according to a study published in the journal... more
Structural basis for allosteric PARP-1 retention on DNA breaks  Science Magazine · 17 hours
The success of poly(ADP-ribose) polymerase–1 (PARP-1) inhibitors (PARPi) to treat cancer relates to their ability to trap PARP-1 at the site of a DNA break. Although different forms of PARPi... more
Contemporaneity of Australopithecus, Paranthropus, and early Homo erectus in South Africa  Science Magazine · 17 hours
Understanding the extinction of Australopithecus and origins of Paranthropus and Homo in South Africa has been hampered by the perceived complex geological context of hominin fossils,... more
De novo design of protein logic gates  Science Magazine · 17 hours
The design of modular protein logic for regulating protein function at the posttranscriptional level is a challenge for synthetic biology. Here, we describe the design of two-input AND, OR, NAND, NOR, XNOR, and NOT... more
Newly discovered biostability in DNA structures may lead to enhanced design of therapeutics  nanowerk · 18 hours
Researchers discovered an already existing biostable DNA motif applicable to the design of new drug carriers and diagnostics. more
Variations in skin-related genes influence how efficient we make vitamin D  NEWS MEDICAL · 19 hours
Genetic variations in the skin can create a natural sunscreen, according to University of Queensland researchers investigating the genes linked with vitamin D. more
Genetic self-activation maintains plant stem cells  PHYS.ORG · 20 hours
Branching allows plants to occupy space in three dimensions, an innovation considered essential for their adaption. Stem cells are key to this process because they promote the establishment of new growth axes. But where do these... more
Researchers unveil the universal properties of active turbulence  PHYS.ORG · 20 hours
Turbulent flows are chaotic yet feature universal statistical properties.Over the recent years, seemingly turbulent flows have been discovered in active fluids such as bacterial suspensions, epithelial cell monolayers, and mixtures of biopolymers... more
Biogazelle initiates large-scale testing of patient samples for SARS-CoV-2  NEWS MEDICAL · 21 hours
Biogazelle NV, a CRO specialized in RNA analytics, has announced the initiation of large-scale testing of patient samples for SARS-CoV-2. Biogazelle is providing one of the multiple testing sites in... more
Breast density, microcalcifications, and masses are heritable features, analysis reveals  NEWS MEDICAL · 1 day
An analysis of a large Swedish cohort revealed that breast density, microcalcifications, and masses are heritable features, and that breast density and microcalcifications were positively associated with a... more
Study proposes method to extend polygenic scores to individuals with mixed ancestry  NEWS MEDICAL · 1 day
A new study in Nature Communications proposes a method to extend polygenic scores, the estimate of genetic risk factors and a cornerstone of the... more
Technique reveals how crystals form on surfaces  MIT · 1 day
DNA-based self-assembling system sheds light on processes essential for semiconductors and nanotechnology. more
How (easily) does the novel coronavirus spread?  NEWS MEDICAL · 1 day
Viruses are tiny bundles of DNA or RNA which have the ability to infect host cells, hijack the machinery of the host cell and then replicate. Once the host cell’s resources are exhausted, the... more
Hereditary genetic defect linked to medulloblastoma destabilizes protein regulation  NEWS MEDICAL · 1 day
The causes of 40 percent of all cases of certain medulloblastoma - dangerous brain tumors affecting children - are hereditary. more
Healthy Nevada Project participants report on possible exposure and risks of COVID-19  NEWS MEDICAL · 1 day
The Healthy Nevada Project, a first-of-its-kind, community-based population health study combining genetic, clinical, environmental and social data, offers free genetic testing to every Nevadan... more
Rutgers' RUCDR Infinite Biologics launches genetic test for novel coronavirus  NEWS MEDICAL · 2 days
Rutgers' RUCDR Infinite Biologics has launched a test for the SARS-CoV-2 coronavirus and is using its automation experience and infrastructure to test as many as tens of thousands... more
Researchers identify risk gene for Alzheimer's development  NEWS MEDICAL · 2 days
Researchers from the University of British Columbia and the Central South University in China have for the first time identified a gene that increases the risk of Alzheimer's disease. more
Inherited gene mutation can predispose children to SHH medulloblastoma  NEWS MEDICAL · 2 days
Investigators at St. Jude Children's Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup... more
Modern humans, Neanderthals share a tangled genetic history, study affirms  PHYS.ORG · 2 days
In recent years, scientists have uncovered evidence that modern humans and Neanderthals share a tangled past. In the course of human history, these two species of hominins interbred... more
Modern humans, Neanderthals share a tangled genetic history, study affirms  SCIENCE DAILY · 2 days
A new study reinforces the concept that Neanderthal DNA has been woven into the modern human genome on multiple occasions as our ancestors met Neanderthals time and again... more
Physical force alone spurs gene expression, study reveals  PHYS.ORG · 2 days
Cells will ramp up gene expression in response to physical forces alone, a new study finds. Gene activation, the first step of protein production, starts less than one millisecond after a cell... more
Evolutionary adaptation helped cave bears hibernate, but may have caused extinction  PHYS.ORG · 2 days
A study published in Science Advances on April 1 reveals a new hypothesis that may explain why European cave bears went extinct during past climate change... more
A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application  Science Magazine · 2 days
Although growth factors have great therapeutic potential because of their regenerative functions, they often have intrinsic drawbacks, such as low... more
The unconventional biogenesis of Kv7.1-KCNE1 complexes  Science Magazine · 2 days
The potassium channel Kv7.1 associates with the KCNE1 regulatory subunit to trigger cardiac IKs currents. Although the Kv7.1/KCNE1 complex has received much attention, the subcellular compartment hosting the assembly is the subject of ongoing debate. Evidence... more
Understanding brain tumors in children  SCIENCE DAILY · 2 days
The causes of 40% of all cases of certain medulloblastomas -- dangerous brain tumors affecting children -- are hereditary. A genetic defect that occurs in 15% of these children plays a key role by destabilizing the production of... more
Oldest ever human genetic evidence clarifies dispute over our ancestors  SCIENCE DAILY · 2 days
Genetic information from an 800,000-year-old human fossil has been retrieved for the first time. The results shed light on one of the branching points in the human family... more
First complete German shepherd DNA offers new tool to fight disease  PHYS.ORG · 2 days
Scientists have mapped the genome of the German shepherd, one of the world's most popular canine breeds, after using a blood sample from 'Nala,' a healthy... more
Researchers develop novel corona test  PHYS.ORG · 2 days
As requested by the Austrian Federal Government and the WHO, a significant increase in the capacity for coronavirus testing is essential to combat the new coronavirus. The University of Innsbruck is now responding to this by immediately developing... more
Oldest-ever human genetic evidence clarifies dispute over our ancestors  PHYS.ORG · 2 days
Genetic information from an 800,000-year-old human fossil has been retrieved for the first time. The results from the University of Copenhagen shed light on one of the branching points in... more
Thermo Fisher announces availability of AcroMetrix Coronavirus 2019 (COVID-19) RNA Control  NEWS MEDICAL · 2 days
Thermo Fisher Scientific, the world leader in serving science, today announced the availability of the Thermo Scientific AcroMetrix Coronavirus 2019 (COVID-19) RNA Control, its latest quality... more
Insight into how insects sense and process pain and other negative stimuli  PHYS.ORG · 2 days
Scientists know that most organisms react to things that cause them pain, but they know more about some species than others. Take the fruit... more
Using sound and environmental DNA to find an elusive, endangered whale  PHYS.ORG · 2 days
In an ongoing effort to detect endangered Bryde's whales, the National Oceanic and Atmospheric Administration (NOAA) and MBARI have teamed up to deploy an Environmental Sample... more
Newly-Discovered Gene Mutation Improves Cognitive Flexibility in Mice  SCI-NEWS.COM · 2 days
A team of U.S. researchers has discovered a genetic mutation that improves cognitive flexibility in mice. Electrical signals stimulate chemical... more
Study: Genetic and neural factors influence ADHD diagnosis  NEWS MEDICAL · 2 days
Genetic studies of attention-deficit/hyperactivity disorder (ADHD) show that it takes many common genetic variations combining together in one individual to increase risk substantially. more
Study identifies three unknown genetic mechanisms that cause myopia  NEWS MEDICAL · 2 days
Three previously unknown genetic mechanisms have been discovered in causing myopia otherwise known as short or near-sightedness, finds a new study. more
Scientists unravel a new mechanism that triggers cell death and inflammation  NEWS MEDICAL · 2 days
Z-form nucleic acids are double-stranded DNA and RNA molecules with an unusual left-handed double helix structure, as opposed to the classical right-handed Watson-Crick double helix. Z-nucleic... more
Stellenbosch University and AzarGen Biotechnologies join forces to tackle COVID-19  NEWS MEDICAL · 2 days
Stellenbosch University in South Africa and AzarGen Biotechnologies (Pty) Ltd, a South African biotechnology company focused on developing human therapeutic proteins using advanced genetic engineering and synthetic biology... more
Researchers discover new biomarker for early detection of Alzheimer's disease  NEWS MEDICAL · 2 days
Researchers at the University of California San Diego discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection... more
NIH researchers identify a second gene that causes melorheostosis  NEWS MEDICAL · 3 days
Researchers at the National Institutes of Health have discovered a second gene that causes melorheostosis, a rare group of conditions involving an often painful and disfiguring overgrowth of bone tissue. more
A new mechanism triggering cell death and inflammation: A left turn that kills  SCIENCE DAILY · 3 days
Researchers describe their discovery of a new mechanism that could contribute to the pathogenesis of inflammatory diseases. The scientists found that ZBP1,... more
Novel approach to DNA synthesis could help tackle COVID-19 pandemic  NEWS MEDICAL · 3 days
Synthetic biology, and particularly DNA synthesis, is transforming diagnosis and treatment of disease, and may yet play a key role in halting the COVID-19 pandemic. more
Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19  NEWS MEDICAL · 3 days
Cobra Biologics, an international CDMO for biologics and pharmaceuticals, and the Karolinska Institutet, one of the world’s leading medical universities, today announced... more
The unlikely story of the green peafowl  PHYS.ORG · 3 days
We all know that habitat loss is pushing many species to the brink of extinction, with the conversion of forests for agricultural use a particular problem. more
Researchers reveal mechanism of trimming longer RNA transcripts to become micro RNA  PHYS.ORG · 3 days
A particular group of non-coding RNAs (ncRNAs) known as microRNAs (miRNAs) are ~22 nucleotide (nt) in length and play vital roles in diverse physiological... more
Scientists find a practical approach to improve differential gene expression analysis  PHYS.ORG · 3 days
Identification of differentially expressed genes (DEGs) is a fundamental step for many biomedical studies. RNA-sequencing is the most popular approach for this purpose and is widely... more
How to quickly and efficiently identify huge gene data sets to help coronavirus research  PHYS.ORG · 3 days
Thanks to the advancement of sequencing technology, it's possible to produce massive amounts of genome sequence data on various species.... more
Defaunation in rainforests could have more severe consequences than reported  PHYS.ORG · 3 days
Tropical rainforests are emptying out due to the ongoing extinction of animal species caused by overhunting and forest fragmentation. But not only species as such, also the number... more
Mystery solved: The origin of the colors in the first color photographs  PHYS.ORG · 3 days
A palette of colors on a silver plate: That is what the world's first color photograph looks like. It was taken by French physicist... more
Her genetic test revealed a microscopic problem — and a jumbo price tag  NEWS MEDICAL · 3 days
Michelle Kuppersmith, 32, feels great, works full time and exercises three to four times a week. So she was surprised when a... more
UVA researchers find way to enhance cancer outcomes by examining patients' genetic data  NEWS MEDICAL · 3 days
By mining a vast trove of genetic data, researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to... more
Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal  NEWS MEDICAL · 3 days
An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following... more
New blood test accurately detects more than 50 types of cancer  NEWS MEDICAL · 3 days
Researchers have developed a blood test that could accurately detect up to 50 types of cancers, and some of these detections could be even before the... more
Brazil's Carnival beat fades, making way for virus shelter  ABC NEWS · 3 days
A month ago, Rio de Janeiro’s Sambadrome was the site of a massive Carnival party bursting with samba music and smiling faces more
Zebrafish can provide genetic clues to human nicotine addiction  NEWS MEDICAL · 4 days
Researchers at Queen Mary University of London have shown that zebrafish can provide genetic clues to smoking, a complex human behavior. more
Researchers find way to improve cancer outcomes by examining patients' genes  SCIENCE DAILY · 4 days
Genetics researchers say a new approach could benefit all sorts of serious health conditions, and they're urging scientists to quickly pluck 'low hanging fruit' for the... more
Newly discovered enzyme “square dance” helps generate DNA building blocks  MIT · 4 days
MIT biochemists can trap and visualize an enzyme as it becomes active — an important development that may aid in future drug development. more
Hidden messages in protein blueprints  SCIENCE DAILY · 4 days
Scientists have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations. For this purpose, the stem cells simultaneously modify the blueprints for hundreds of proteins encoded in the gene transcripts. In... more
Hidden messages in protein blueprints  PHYS.ORG · 4 days
Scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute of Stem Cell Technology and Experimental Medicine (HI-STEM) and the Max Planck Institute in Freiburg have identified a new control mechanism that enables stem cells to... more
Rheumatic diseases: The cost of survival during the Little Ice Age  PHYS.ORG · 4 days
A study by the Human Evolutionary Biology Group at the UPV/EHU-University of the Basque Country provides clues about the prevalence of a certain genetic profile in... more
Gene that could affect the progress of ALS discovered  NEWS MEDICAL · 4 days
Researchers from the Zuckerman Institute at Columbia University have successfully found a gene that could work towards accelerating the progression of ALS or amyotrophic lateral sclerosis. The study titled, "The... more
Genetic mutation found to improve cognitive flexibility in mice  NEWS MEDICAL · 6 days
Researchers at the National Institutes of Health have discovered in mice what they believe is the first known genetic mutation to improve cognitive flexibility--the ability to adapt to changing situations. more
Researchers examining gene coexpression and brain connectivity in females with ASD  NEWS MEDICAL · 6 days
Allison Jack, Assistant Professor, Psychology, is examining gene coexpression and brain connectivity in females with autism spectrum disorder. more
Columbia scientists provide new insights into how mutations in a gene cause ALS  NEWS MEDICAL · 6 days
Columbia scientists have provided new insights into how mutations in a gene called TBK1 cause amyotrophic lateral sclerosis, a progressive neurodegenerative disease... more
Scientists discover a completely new antibiotic resistance gene  NEWS MEDICAL · 7 days
Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria. more
In Earth's largest extinction, land animal die-offs began long before marine extinction  SCIENCE DAILY · 7 days
Because of poor dates for land fossils laid down before and after the mass extinction at the end of the Permian, paleontologists assumed that... more
Rheumatism: New clues about the prevalence of certain genetic profile in Europeans  NEWS MEDICAL · 7 days
A piece of research by the Human Evolutionary Biology Group at the UPV/EHU-University of the Basque Country provides clues about the prevalence of a... more
How sick will the coronavirus make you? The answer may be in your genes  Science Magazine · 7 days
Projects drawing on large biobanks and COVID-19 patients aim to find genetic differences that predict who will get seriously ill... more
Gene therapy investigators can greatly benefit from National Gene Vector Biorepository  NEWS MEDICAL · 7 days
Gene therapy investigators can greatly benefit from the resources and services provided by the National Gene Vector Biorepository, housed at the Indiana University School of Medicine. more
DNA riddle unravelled: How cells access data from 'genetic cotton reels'  SCIENCE DAILY · 7 days
With so much genetic information packed in such a tiny space, how cells access DNA when it needs it is something of a mystery. Research has... more
Gene mutation enhances cognitive flexibility in mice  SCIENCE DAILY · 7 days
Researchers have discovered in mice what they believe is the first known genetic mutation to improve cognitive flexibility -- the ability to adapt to changing situations. more
Scientists create triple-threat genetic toolkit for producing eco-friendly chemicals  PHYS.ORG · 7 days
Researchers have developed a triad of innovative tools to engineer low-pH-tolerant yeast Issatchenkia orientalis for production of valuable bioproducts from renewable biomass. more
MAP4K4 negatively regulates CD8 T cell-mediated antitumor and antiviral immunity  Science Magazine · 7 days
During cytotoxic T cell activation, lymphocyte function-associated antigen–1 (LFA-1) engages its ligands on antigen-presenting cells (APCs) or target cells to enhance T cell priming or lytic activity. Inhibiting... more
Targeted gene silencing in vivo by platelet membrane-coated metal-organic framework nanoparticles  Science Magazine · 7 days
Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a wide range of biomedical applications, but there are many... more
Researchers take a big step towards a comprehensive single-cell atlas  PHYS.ORG · 7 days
A large team of researchers affiliated with multiple institutions in and around Hangzhou, China, has taken a very large step toward the creation of a comprehensive human single-cell... more
Completely new antibiotic resistance gene has spread unnoticed to several pathogens  SCIENCE DAILY · 7 days
Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria. A completely new resistance gene, which is likely to counteract the newest... more
Completely new antibiotic resistance gene has spread unnoticed to several pathogens  PHYS.ORG · 7 days
Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria. A completely new resistance gene, which is likely to counteract the newest... more
Mayor: NYC needs federal help to curb virus' mounting toll  ABC NEWS · 7 days
New York City Mayor Bill de Blasio is calling on the federal government to help New York treat the growing numbers of coronavirus patients more
Capabilities of CRISPR gene editing expanded  PHYS.ORG · 7 days
Many basic and clinical researchers are testing the potential of a simple and efficient gene editing approach to study and correct disease-causing mutations for conditions ranging from blindness to cancer, but the technology is constrained by... more
Global scientific collaboration produces first genetic map of the cerebral cortex  NEWS MEDICAL · 1 week
The cerebral cortex is the relatively thin, folded, outer "gray matter" layer of the brain crucial for thinking, information processing, memory, and attention. more
Removing a gene prevents Type 1 diabetes in mice by disguising beta cells  NEWS MEDICAL · 1 week
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack... more
Worldwide scientific collaboration unveils genetic architecture of gray matter  SCIENCE DAILY · 1 week
For the first time, more 360 scientists from 184 different institutions have contributed to a global effort to find more than 200 regions of the genome and more than 300... more
The genetic quest to understand COVID-19  SCIENCE DAILY · 1 week
The novel coronavirus SARS-CoV-2 that causes COVID-19 is now likely to become the fifth endemic coronavirus in humans. Scientists are working to decipher its genome to help us stop other coronaviruses entering the human population. more
The Coronavirus Is Mutating Relatively Slowly, Which May Be Good News  NPR · 1 week
As a virus makes copies of itself, errors may creep in, changing its genetic makeup. Researchers are trying to determine if the changes are significant in... more
A quest to unlock the genetic code of SARS-CoV-2  NEWS MEDICAL · 1 week
How the novel coronavirus that causes COVID-19 made the leap from animals to humans is a puzzle that scientists are trying to solve as humanity comes to grip with the... more
Jumping genes help make functional brain cells in a lab dish  NEWS MEDICAL · 1 week
The process of making functional brain cells in a lab dish requires the precise activation of selfish genetic elements known as LINE-1 (L1) retrotransposons. more
Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants  Science Magazine · 1 week
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove this constraint, we engineered variants of... more
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