Genetics
Medical News Today: Alzheimer's: Common gene explains why some drugs fail  MNT · 50 minutes
A new study helps to explain why some Alzheimer’s drugs work in some people but not in others, and why some yet may succeed in animals... more
Medical News Today: Can we blame procrastination on our genes?  MNT · 50 minutes
New research has found a genetic difference in procrastinators, but there is a catch. The research also reveals important sex differences. more
Can we blame procrastination on our genes?  MNT · 56 minutes
New research has found a genetic difference in procrastinators, but there is a catch. The research also reveals important sex differences. more
Genetic similarities of deadly bone cancer between dogs and children revealed  NEWS MEDICAL · 2 hours
A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a study published today by Tufts University... more
To return to the Moon, astronauts need new spacesuits  PHYS.ORG · 2 days
Space engineer Pablo de Leon has designed two spacesuit prototypes for the Moon and for Mars, and knows how long development takes. more
Boosting the discovery of new drugs to treat spinal cord injuries using zebrafish  SCIENCE DAILY · 2 days
A research team led by Leonor Saúde, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has... more
Genetic similarities of osteosarcoma between dogs and children  SCIENCE DAILY · 2 days
A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a new study. The findings could help break the logjam in the treatment... more
Shedding light on darker parts of our genetic heritage  SCIENCE DAILY · 2 days
More than half of our genome consists of transposons, DNA sequences that are reminiscent of ancient, extinct viruses. Transposons are normally silenced by a process known as DNA methylation, but their activation... more
Largest genomic study on type 2 diabetes in sub-Saharan African populations  SCIENCE DAILY · 2 days
Researchers have performed the largest GWAS study on type 2 diabetes in the sub-Saharan African populations, revealing an association between the disease and previously unlinked ZRANB3... more
Medical News Today: Metabolic factors likely contribute to anorexia  MNT · 2 days
A genetic study suggests that anorexia nervosa has metabolic as well as psychiatric components and opens the door to new treatments for the illness. more
Programmable dynamic steady states in ATP-driven nonequilibrium DNA systems  Science Magazine · 2 days
Inspired by the dynamics of the dissipative self-assembly of microtubules, chemically fueled synthetic systems with transient lifetimes are emerging for nonequilibrium materials design. However, realizing programmable or even adaptive structural... more
Metabolic factors likely contribute to anorexia  MNT · 2 days
A genetic study suggests that anorexia nervosa has metabolic as well as psychiatric components and opens the door to new treatments for the illness. more
Fishing for genes  PHYS.ORG · 2 days
Just as steelhead trout migrate from saltwater to freshwater and back, MBARI's Environmental Sample Processors (ESPs)—first developed for research in the ocean—have been getting a lot of use in freshwater over the last five years. more
Novel mechanism of inheritance detected  PHYS.ORG · 3 days
Non-Mendelian, oligogenic inheritance could be an unrecognized and important element for occurrence of hereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness. more
New genome editing technology for plant breeding  PHYS.ORG · 3 days
Researchers have developed a new genome editing technology for rice, combining adenine-to-guanine single-base editing technology and Cas9 with an extended targeting scope. They report that it is possible to efficiently introduce base substitution mutations... more
Researchers discover genome-wide variations in gene expression between male and female mammals  PHYS.ORG · 3 days
A team of researchers affiliated with several institutions in the U.S. has discovered genome-wide variations in gene expression between male and female mammals. In... more
Gene linked to severe liver damage  SCIENCE DAILY · 3 days
Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease. One of the study's major findings is that AEBP1 regulates the expression... more
Adding a polymer stabilizes collapsing metal-organic frameworks  PHYS.ORG · 3 days
Metal-organic frameworks (MOFs) are a special class of sponge-like materials with nano-sized pores. The nanopores lead to record-breaking internal surface areas, up to 7800 m2 in a single gram. This feature makes MOFs extremely... more
Scientists discover group of genes connected to longer life in fruit flies  PHYS.ORG · 3 days
Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies and co-authors from the Institute of biology of Komi Science Center of... more
IDT partners with Washington University to increase access to new NGS technologies  NEWS MEDICAL · 3 days
As part of its commitment to advocate for the genomics age, Integrated DNA Technologies aims to lower the barriers to access the latest NGS... more
Group of genes linked to longer lifespan in fruit flies discovered  NEWS MEDICAL · 3 days
Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the... more
How genetic differences in Epstein-Barr virus strains alter the way it behaves  NEWS MEDICAL · 3 days
Researchers at the University of Sussex have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus... more
Study uncovers gene that hides tumor cells from immunotherapy  NEWS MEDICAL · 3 days
A team at Fred Hutchinson Cancer Research Center has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients. more
Alzheimer's gene may affect cognitive health before adulthood, study finds  NEWS MEDICAL · 3 days
The Apolipoprotein E (APOE) is a major cholesterol carrier that aids in lipid transport and injury repair in the brain. It packages cholesterol and other fats and moves... more
AEBP1 gene may play key role in the development and severity of liver disease  NEWS MEDICAL · 3 days
Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential... more
New research identifies gene that hides cancer cells from immunotherapy  SCIENCE DAILY · 3 days
A team has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients. The study found that when the... more
Genetic differences between strains of Epstein-Barr virus can alter its activity  SCIENCE DAILY · 3 days
Researchers have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus (EBV) can alter the way the virus... more
Alzheimer's gene may impact cognitive health before adulthood  SCIENCE DAILY · 3 days
A psychologist asserts that those carrying the APOE4 gene score lower on IQ tests during childhood and adolescence. And the effect was stronger in girls than in boys. APOE4 carriers are up... more
Manmade ruin adds 7,000 species to endangered 'Red List'  PHYS.ORG · 3 days
Mankind's destruction of nature is driving species to the brink of extinction at an "unprecedented" rate, the leading wildlife conservation body warned Thursday as it added more than 7,000 animals,... more
A New Spin On DNA  SCIENCE DAILY · 3 days
For decades, researchers have chased ways to study biological machines. Every mechanical movement -- from contracting a muscle to replicating DNA -- relies on molecular motors that take near-undetectable steps. Trying to see them move is like trying... more
Researchers identify brain somatic mutations linked to Alzheimer's disease  NEWS MEDICAL · 3 days
Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease. Their findings were published in the journal Nature Communications last week. more
Genetic study takes research on sex differences to new heights  MIT · 3 days
Differences in male and female gene expression, including those contributing to height differences, found throughout the body in humans and other mammals. more
Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses  Science Magazine · 3 days
DNA viruses typically eject genomic DNA into the nuclei of host cells after entry. It is unclear, however, how nuclear pathogen-derived DNA triggers innate... more
Use of a scaffold peptide in the biosynthesis of amino acid-derived natural products  Science Magazine · 3 days
Genome sequencing of environmental bacteria allows identification of biosynthetic gene clusters encoding unusual combinations of enzymes that produce unknown natural products. We... more
Conservation, acquisition, and functional impact of sex-biased gene expression in mammals  Science Magazine · 3 days
Sex differences abound in human health and disease, as they do in other mammals used as models. The extent to which sex differences are conserved at... more
Genetic control for major agricultural weeds?  SCIENCE DAILY · 3 days
Waterhemp and Palmer amaranth, two aggressive weeds that threaten the food supply in North America, are increasingly hard to kill with commercially available herbicides. A novel approach known as genetic control could one day reduce the... more
Fertility doc told to provide DNA sample for paternity test  ABC NEWS · 3 days
A judge says a Vermont fertility doctor accused of using his own sperm to impregnate a patient must turn over a sample of his DNA more
Scientists hope genetic research will lead to new breakthroughs in weed control  PHYS.ORG · 3 days
An article featured in the journal Weed Science sheds important new light on the genetics and potential control of Palmer amaranth and waterhemp—two troublesome... more
More than 28,000 species are officially threatened, with more likely to come  PHYS.ORG · 3 days
More than 28,000 species around the world are threatened, according to the Red List of Threatened Species compiled by the International Union for the... more
Researchers develop a more precise version of CRISPR-Cas9 gene-editing system  NEWS MEDICAL · 3 days
A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model. more
Research team detects novel mechanism of inheritance  NEWS MEDICAL · 4 days
Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness. more
Novel insight into microRNA function can be crucial for the development of gene therapy  NEWS MEDICAL · 4 days
Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally... more
Human genotype determines if a given Alzheimer's drug will be effective  NEWS MEDICAL · 4 days
University at Buffalo researchers have determined that a human gene present in 75 % of the population is a key reason why a class of drugs... more
Human genotype determines if a given Alzheimer's will be effective  NEWS MEDICAL · 4 days
University at Buffalo researchers have determined that a human gene present in 75 % of the population is a key reason why a class of drugs for Alzheimer's... more
New research could help design algae that produces fuels and cleanup chemicals  NEWS MEDICAL · 4 days
It's a case of grand larceny that could lead to new fuels and cleanup chemicals. Ten species of red algae stole about 1 percent... more
Shaky scaffold changes lung infrastructure  SCIENCE DAILY · 4 days
Researchers identify changes in enzymes that may contribute to lung damage in rare genetic disorder. more
Gut infection can lead to a pathology resembling Parkinson's disease  NEWS MEDICAL · 4 days
A new study by Montreal scientists published today in Nature demonstrates that a gut infection can lead to a pathology resembling Parkinson's disease in a mouse model lacking... more
Proposed gene therapy for a heart arrhythmia, based on models made from patient cells  SCIENCE DAILY · 4 days
Researchers report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in... more
Medical News Today: Ehlers-Danlos syndrome: Everything you need to know  MNT · 4 days
Ehlers-Danlos syndrome is a group of genetic disorders that affect the connective tissues and cause several symptoms, including stretchy skin and loose joints. Learn more here. more
First clinical proof that genotypes determine if Alzheimer's drugs will work  SCIENCE DAILY · 4 days
Researchers have determined that a human gene present in 75% of the population is a key reason why a class of drugs for Alzheimer's disease seemed... more
Possible drug target for deadly heart condition  SCIENCE DAILY · 4 days
A genetic mutation linked to dilated cardiomyopathy, a dangerous enlargement of the heart's main pumping chamber, activates a biological pathway normally turned off in healthy adult hearts, according to a new study. more
DNA origami joins forces with molecular motors to build nanoscale machines  nanowerk · 4 days
Researchers have captured the first recorded rotational steps of a molecular motor as it moved from one DNA base pair to another. more
Protein lysine de-2-hydroxyisobutyrylation by CobB in prokaryotes  Science Magazine · 4 days
Lysine 2-hydroxyisobutyrylation (Khib) has recently been shown to be an evolutionarily conserved histone mark. Here, we report that CobB serves as a lysine de-2-hydroxyisobutyrylation enzyme that regulates glycolysis and cell growth in prokaryotes. We... more
Structural basis for the multitasking nature of the potato virus Y coat protein  Science Magazine · 4 days
Potato virus Y (PVY) is among the most economically important plant pathogens. Using cryoelectron microscopy, we determined the near-atomic structure of PVY’s... more
[Focus] Diverse compositions and functions of chromatin remodeling machines in cancer  Science Magazine · 4 days
Human cancer genetics power biochemical and functional interrogation of chromatin remodeling complexes, informing therapeutic opportunities. more
[Editors' Choice] A mitochondrial Pac-man drug to tackle aging  Science Magazine · 4 days
Urolithin A, an activator of mitophagy, is safe to use and increases skeletal muscle mitochondrial gene expression in elderly individuals. more
[Research Articles] A multimodality test to guide the management of patients with a pancreatic cyst  Science Magazine · 4 days
Pancreatic cysts are common and often pose a management dilemma, because some cysts are precancerous, whereas others have... more
DNA origami joins forces with molecular motors to build nanoscale machines  SCIENCE DAILY · 4 days
For decades, researchers have chased ways to study biological machines. Every mechanical movement -- from contracting a muscle to replicating DNA -- relies on molecular motors... more
Red algae steal genes from bacteria to cope with environmental stresses  PHYS.ORG · 4 days
It's a case of grand larceny that could lead to new fuels and cleanup chemicals. Ten species of red algae stole about 1 percent of their... more
Red algae steal genes from bacteria to cope with environmental stresses  SCIENCE DAILY · 4 days
It's a case of grand larceny that could lead to new fuels and cleanup chemicals. Ten species of red algae stole about 1 percent of their... more
New insight into microRNA function can give gene therapy a boost  SCIENCE DAILY · 4 days
Scientists have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei. Previously, microRNAs were mainly thought to be... more
'Semi-synthetic' bacteria churn out unnatural proteins  SCIENCE DAILY · 4 days
Synthetic biologists seek to create new life with forms and functions not seen in nature. Although scientists are a long way from making a completely artificial life form, they have made semi-synthetic organisms that have an... more
A study analyzes the influence of political affinities in the processes of socialization  PHYS.ORG · 4 days
A study in which the Universidad Carlos III de Madrid participated (UC3M) has concluded that most people prefer not to have much... more
Little genes, big conservation: Scientists study genetic rescue  PHYS.ORG · 4 days
At first glance, there aren't many similarities between westslope cutthroat trout in Montana, wolves on Isle Royale National Park in Michigan and Australia's mountain pygmy possum, a mouse-sized alpine marsupial. more
Newly discovered cattle genes could be keys to more sustainable beef industry  PHYS.ORG · 4 days
A newly discovered series of genes related to feed efficiency could pave the way to making cattle farming cheaper and more sustainable, according to... more
'Semi-synthetic' bacteria churn out unnatural proteins  PHYS.ORG · 4 days
Synthetic biologists seek to create new life with forms and functions not seen in nature. Although scientists are a long way from making a completely artificial life form, they have made semi-synthetic organisms that have an... more
Little genes, big conservation: Scientists study genetic rescue  SCIENCE DAILY · 4 days
A new article examines the potential and uncertainties of attempting genetic rescue, a conservation approach that involves moving a small number of individual animals from one population to another to reduce genetic... more
Forest elephants are allies in the fight against climate change, finds research  PHYS.ORG · 4 days
Forest elephant extinction would exacerbate climate change. That's according to a new study in Nature Geoscience which links feeding by elephants with an increase... more
New insight into microRNA function can give gene therapy a boost  PHYS.ORG · 4 days
Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also... more
Unmasking mutant cancer cells  MIT · 4 days
A new dosing regimen for an old cancer drug shows new promise as an immunotherapy. more
Living longer or healthier? Genetic discovery in worms suggests they can be separated  SCIENCE DAILY · 5 days
Gene identified in worms controls how resources are allocated for stress resilience, longevity and fertility. more
Molecular switches may control lifespan and healthspan separately, genetic discovery suggests  NEWS MEDICAL · 5 days
Aging research indicates that better healthspan--the quality of life as we age--may be more important than lifespan. more
Research opens possibility of developing single-dose gene therapy for inherited arrhythmias  NEWS MEDICAL · 5 days
Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish,... more
Living longer or healthier? Genetic discovery in worms suggests they can be separated  PHYS.ORG · 5 days
In a report published today in Nature Communications, a surprising new genetic discovery by researchers at the University of Pittsburgh School of... more
Researchers find a method to select for haploid mammalian cells  PHYS.ORG · 5 days
Since the emergence of molecular genetics more than 50 years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes... more
Joshua Trees Will Be All-But-Extinct by 2070 Without Climate Action, Study Warns  LIVE SCIENCE · 5 days
More than 80% of California's iconic Joshua trees are likely to die at the hands of drought and fire over the next 50 years... more
Researchers identify chemical compounds that increase stability of haploid cell  NEWS MEDICAL · 5 days
Since the emergence of molecular genetics more than fifty years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes... more
Slug serves as 'command central' for determining breast stem cell health  NEWS MEDICAL · 5 days
A new study published in Cell Reports found that a transcription factor called Slug serves as 'command central' for determining breast stem cell health, regulating both... more
Study explores role of iron in over 900 diseases  NEWS MEDICAL · 5 days
In a series of early-stage studies examining genetic data from over 500,000 people, a team of international scientists, led by Imperial College London, explored the role that iron plays in... more
Gene modulation goes wireless hacking the "boss gene"  NEWS MEDICAL · 5 days
Researchers from the University at Buffalo have successfully used technology to wirelessly tweak the functioning of a gene FGFR1. This gene is vital in the growth of embryos into adults. Their experiments... more
Boosting genetic diversity may save vanishing animal populations. But it may also backfire  Science Magazine · 5 days
Long-running experiments can help conservationists plan rescues that don’t swamp small animal groups’ unique adaptations more
Joshua trees facing extinction  SCIENCE DAILY · 5 days
They outlived mammoths and saber-toothed tigers. But without dramatic action to reduce climate change, new research shows Joshua trees won't survive much past this century. more
Should we resurrect the American chestnut tree with genetic engineering?  PHYS.ORG · 5 days
The wild chestnuts around this leafy college town used to grow in such great numbers that locals collected the nuts by the bushel and shipped them off to... more
Researchers wirelessly hack 'boss' gene, a step toward reprogramming the human genome  SCIENCE DAILY · 5 days
A new study describes how researchers wirelessly controlled FGFR1 -- a gene that plays a key role in how humans grow from embryos to... more
Long live the long-limbed African chicken  SCIENCE DAILY · 5 days
For generations, household farmers in the Horn of Africa have selectively chosen chickens with certain traits that make them more appealing. Some choices are driven by the farmers' traditional courtship rituals; others are guided by more... more
Method to select for mammalian cells with half the number of chromosomes  SCIENCE DAILY · 5 days
Since the emergence of molecular genetics, scientists have tried to isolate haploid mammalian cells. Haploid cells are a powerful genetic tool to analyse gene... more
Slug, a stem cell regulator, keeps breast cells healthy by promoting repair of DNA damage  SCIENCE DAILY · 5 days
A new biomedical research study finds a transcription factor called Slug contributes to breast cell fitness by promoting... more
The protein that gives identical cells individuality  SCIENCE DAILY · 5 days
New insight into a protein's role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments. more
Ancient DNA extracted from Neanderthal fossils of Gibraltar for the first time  PHYS.ORG · 6 days
A new collaborative study, led by the Natural History Museum and the Max Planck Institute for Evolutionary Anthropology, has extracted ancient DNA from the... more
Better genome editing for bioenergy  PHYS.ORG · 6 days
CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for bioenergy applications. Cas9 needs guide RNA to lead it to the correct sequence to snip—but not all guides are effective. To ensure the gene... more
The protein that gives identical cells individuality  PHYS.ORG · 6 days
New insight into a protein's role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments. more
Differences in genes impact response to cryptococcus infection  SCIENCE DAILY · 6 days
Cryptococcus neoformans is a fungal pathogen that infects people with weakened immune systems, particularly those with advanced HIV/AIDS. New research could mean a better understanding of this infection and potentially better treatments... more
Loose double-stranded RNA molecules spur skin rejuvenation  NEWS MEDICAL · 6 days
Want to smooth out your wrinkles, erase scars and sunspots, and look years younger? Millions of Americans a year turn to lasers and prescription drugs to rejuvenate their skin, but exactly how that rejuvenation... more
EMBL study reveals uncoupling between chromatin topology and gene expression  NEWS MEDICAL · 6 days
Molecular biologists long thought that domains in the genome’s 3D organization control how genes are expressed. more
DNACRISPR
More than 28,000 species are officially threatened, with more likely to come
PHYS.ORG
Researchers image molecules as they change charge states for first time
PHYS.ORG
DNA analysis reveals cryptic underwater ecosystem engineers
PHYS.ORG
We spoke to survivalists prepping for disaster: here's what we learned about the end of the world
PHYS.ORG
Fresh