Genetics
Geneticists continue to unravel how genes impact drug use and addiction  SCIENCE DAILY · 4 hours
Research is revealing new insights into how genes impact drug use and addiction through a novel study of susceptibility to the effects of cocaine and methamphetamine... more
Developing biosecurity tool to detect genetically engineered organisms in the wild  SCIENCE DAILY · 4 hours
If a genetically or synthetically engineered organism gets into the environment, how will we tell it apart from the millions of naturally occurring microorganisms? Recently, the... more
Researchers create most complete model of complex protein machinery  PHYS.ORG · 5 hours
Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the... more
Chemical engineers develop biosecurity tool to detect genetically engineered organisms in the wild  PHYS.ORG · 5 hours
If a genetically or synthetically engineered organism is released into the environment, how will we know? How can we tell it apart... more
Life in evolution's fast lane  PHYS.ORG · 7 hours
Most living things have a suite of genes dedicated to repairing their DNA, limiting the rate at which their genomes change through time. But scientists at Vanderbilt and University of Wisconsin-Madison have discovered an ancient lineage of budding... more
DNA analysis of shark barf tells scientists what kinds of birds the sharks scavenge  PHYS.ORG · 8 hours
Tiger sharks have a reputation for being the "garbage cans of the sea"—they'll eat just about anything, from dolphins and... more
After GWAS studies, how to narrow the search for genes?  SCIENCE DAILY · 8 hours
Genome-wide association studies (GWAS) often turn up a long list of genes that MIGHT help cause the trait of interest. Many algorithms can help scientists prioritize which genes... more
Scientists create bacteria with man-made DNA  NEWS MEDICAL · 10 hours
In a landmark research study, a living organism (E. coli) has been made using entirely human-made DNA. more
Why lack of sleep is bad for your heart  SCIENCE DAILY · 11 hours
People who sleep fewer than 7 hours per night have lower levels of gene-regulating molecules, or microRNAs, which help dampen down inflammation in cells and support vascular health. more
Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds  NEWS MEDICAL · 12 hours
Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal... more
A 'biomultimeter' to measure RNA and protein production in real-time  PHYS.ORG · 14 hours
Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that... more
New approach to waking up sleeping genes could help people with Prader-Willi syndrome  NEWS MEDICAL · 18 hours
New funding is enabling Walter and Eliza Hall Institute researchers to develop new approaches to potentially help people with Prader-Willi syndrome, a... more
Synthetic biologists hack bacterial sensors  SCIENCE DAILY · 1 day
Synthetic biologists have hacked bacterial sensing with a plug-and-play system that could be used to mix-and-match tens of thousands of sensory inputs and genetic outputs. more
SABER tech gives DNA and RNA visualization a boost  SCIENCE DAILY · 1 day
A collaborative research team has now developed 'Signal Amplification by Exchange Reaction' (SABER), a highly programmable and practical method that significantly enhances the sensitivity as well as customization and multiplexing... more
Synthetic biologists hack bacterial sensors  PHYS.ORG · 1 day
Rice University synthetic biologists have hacked bacterial sensing with a plug-and-play system that could be used to mix-and-match tens of thousands of sensory inputs and genetic outputs. The technology has wide-ranging implications for medical diagnostics, the study of... more
SABER tech gives DNA and RNA visualization a boost  PHYS.ORG · 1 day
Researchers have been using "Fluorescence in situ hybridization" (FISH) analysis for decades to literally fish for specific DNA and RNA sequences in intact cells and tissues within their vast seas... more
Climate change has long-term impact on species adaptability  PHYS.ORG · 1 day
Historic climate change events can have a lasting impact on the genetic diversity of a species, reveals a new study published in Current Biology. This unexpected finding emerged from an analysis of... more
Structural and functional mechanisms of a new class of bacterial sigma/anti-sigma factors revealed  PHYS.ORG · 1 day
Transcription is the process of synthesizing messenger RNA by RNA polymerase based on the DNA sequence of a gene and is the... more
Managing mutations of a species: the evolution of dog breeding  PHYS.ORG · 1 day
In the first edition of On the Origin of Species, Charles Darwin mentions dogs 54 times. He does so mainly because the extraordinary variation between dog breeds provides... more
Gene linked to rare progressive brain disease causes new kind of congenital disorder  NEWS MEDICAL · 2 days
A new kind of congenital disorder caused by a group of mutations in a gene previously linked only to a rare progressive... more
Broccoli contains an ingredient that could target the "Achilles’ heel" of cancers  NEWS MEDICAL · 2 days
A new study from the Beth Israel Deaconess Medical Center has come up with a new study that reveals that broccoli, Brussels sprouts, kale,... more
Read the Long-Lost Letter from Alexander Hamilton to the Marquis de Lafayette, Stolen 60 Years Ago  LIVE SCIENCE · 4 days
A 1780 letter from Alexander Hamilton to the Marquis de Lafayette has finally resurfaced after being... more
Clinical trial improves treatment of genetic rickets  SCIENCE DAILY · 4 days
A new study shows a drug to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies. more
Nanoscale sculpturing leads to unusual packing of nanocubes  nanowerk · 4 days
Cube-shaped nanoparticles with thick shells of DNA assemble into a never-before-seen 3-D 'zigzag' pattern that breaks orientational symmetry; understanding such nanoscale behavior is key to engineering new materials with desired organizations and... more
Nanoscale sculpturing leads to unusual packing of nanocubes  PHYS.ORG · 4 days
From the ancient pyramids to modern buildings, various three-dimensional (3-D) structures have been formed by packing shaped objects together. At the macroscale, the shape of objects is fixed and thus dictates how... more
Dangerous pathogens use this sophisticated machinery to infect hosts  PHYS.ORG · 4 days
Gastric cancer, Q fever, Legionnaires' disease, whooping cough—though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.... more
B cells engineered to express pathogen-specific antibodies protect against infection  Science Magazine · 4 days
Effective vaccines inducing lifelong protection against many important infections such as respiratory syncytial virus (RSV), HIV, influenza virus, and Epstein-Barr virus (EBV) are not yet available despite decades... more
Owning a dog is influenced by our genetic make-up  SCIENCE DAILY · 4 days
Scientists have studied the heritability of dog ownership using information from 35,035 twin pairs from the Swedish Twin Registry. The new study suggests that genetic variation explains more than half... more
New computer program can help crack precision medicine  PHYS.ORG · 4 days
Researchers from ANU have helped develop a new computer program to find out a person's genetic make-up, bringing us a step closer to an era of precision medicine. more
Changes in subsistence hunting threaten local food security  PHYS.ORG · 4 days
Scientists with the Universidad San Francisco de Quito and WCS Ecuador Program publishing in the journal BioTropica say that subsistence hunting in Neotropical rain forests—the mainstay of local people as a source... more
Wild wheat relative genes to aid in battle against trio of pests  PHYS.ORG · 5 days
Wheat curl mite, greenbug and Hessian fly have long been troublemaker pests for Texas wheat, but a team of Texas A&M AgriLife Research scientists... more
The USDA announces new vision for animal genomics  PHYS.ORG · 5 days
A new U.S. Department of Agriculture (USDA) blueprint, published today in Frontiers and Genetics, will serve as a guide for research and funding in animal genomics for 2018-2027 that will facilitate genomic... more
Macroscopic electron quantum coherence in a solid-state circuit  PHYS.ORG · 5 days
A team of researchers at the Centre de Nanosciences et de Nanotechnologies (C2N, CNRS/Univ. Paris-Saclay) has experimentally achieved the coherent propagation of electrons in circuits over macroscopic distances through a novel nano-engineering... more
Dog ownership strongly linked to DNA make-up, says new study  NEWS MEDICAL · 5 days
A surprising new study shows that the difference in genetic blueprint explains more than 50% of the variation between those who choose to own dogs and those who... more
Researchers identify first gene that predisposes to fainting  NEWS MEDICAL · 5 days
Fainting is not solely caused by external factors. Your genes also play a part. This has recently been documented by research team from the University of Copenhagen, Statens Serum Institut and Rigshospitalet. more
Brain changes in autism traced to specific cell types  SCIENCE DAILY · 5 days
Changes in gene activity in specific brain cells are associated with the severity of autism in children and young adults with the disorder, according to a new study. more
Natural compound found in broccoli reawakens the function of potent tumor suppressor  SCIENCE DAILY · 5 days
Long associated with decreased risk of cancer, broccoli and other cruciferous vegetables -- the family of plants that also includes cauliflower, cabbage, collard greens,... more
How host-cell enzymes combat the coronavirus  SCIENCE DAILY · 5 days
Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a new study. more
Mutation makes bulldogs and Norwich terriers more susceptible to breathing problems  SCIENCE DAILY · 5 days
The discovery of a new mutation associated with breathing difficulties in popular dog breeds suggests that shortened skulls causing flat faces is not the only factor... more
Identification of a regeneration-organizing cell in the Xenopus tail  Science Magazine · 5 days
Unlike mammals, Xenopus laevis tadpoles have a high regenerative potential. To characterize this regenerative response, we performed single-cell RNA sequencing after tail amputation. By comparing naturally occurring regeneration-competent and -incompetent... more
Single-cell genomics identifies cell type-specific molecular changes in autism  Science Magazine · 5 days
Despite the clinical and genetic heterogeneity of autism, bulk gene expression studies show that changes in the neocortex of autism patients converge on common genes and pathways. However, direct assessment... more
De novo design of tunable, pH-driven conformational changes  Science Magazine · 5 days
The ability of naturally occurring proteins to change conformation in response to environmental changes is critical to biological function. Although there have been advances in the de novo design of stable proteins... more
How host-cell enzymes combat the coronavirus  PHYS.ORG · 5 days
Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa,... more
Dog DNA find could aid quest to help breeds breathe more easily  PHYS.ORG · 5 days
Scientists have discovered a DNA mutation linked to breathing problems in popular dog breeds. more
Study reports breakthrough to measure plant improvements to help farmers boost production  PHYS.ORG · 5 days
An international team is using advanced tools to develop crops that give farmers more options for sustainably producing more food on less land. To... more
Global invasion routes of the red swamp crayfish, described based on genetics  SCIENCE DAILY · 5 days
Researchers have identified the main introduction routes of the red swamp crayfish, Procambarus clarkii, during its global-scale invasion. This North American species is the... more
Key step in cell protein production  SCIENCE DAILY · 5 days
Scientists have discovered how genes create proteins in research which could aid the development of treatments for human diseases. more
The global invasion routes of the red swamp crayfish  PHYS.ORG · 5 days
Spanish National Research Council (CSIC) researchers have reconstructed the invasion routes followed by the red swamp crayfish during its human-driven expansion based on the analysis of a mitochondrial gene (COI),... more
Study uncovers key step in cell protein production  PHYS.ORG · 5 days
Scientists at the University of Sheffield have discovered how genes create proteins in research which could aid the development of treatments for human diseases. more
First gene that increases the risk of fainting identified  SCIENCE DAILY · 5 days
Fainting is not solely caused by external factors. Your genes also play a part. Based on data from more than 400,000 individuals they have identified the first gene that predisposes... more
Some dog breeds may have trouble breathing because of a mutated gene  SCIENCE-NEWS · 5 days
Norwich terriers don’t have flat snouts, but can suffer the same wheezing as bulldogs. It turns out that a gene mutation tied to swelling... more
Analysis of the Palaeolithic diet shows no social divisions in food consumption  PHYS.ORG · 5 days
Biochemical analysis of human remains has become a key feature in our understanding of past peoples. Ancient DNA and stable isotope analysis are now... more
Researchers replace the genes of E. coli bacteria with synthesized genome  PHYS.ORG · 5 days
A team of researchers at Cambridge University has replaced the genes of E. coli bacteria with genomes they synthesized in the lab. In their paper published... more
TSU physicists are investigating the effects of radiation on DNA  PHYS.ORG · 6 days
Scientists from TSU's Laboratory of Experimental High Energy Physics and their colleagues from the University of Bordeaux are studying new ways of modeling the effects of low doses... more
Visualizing microglia in brain tissue with a fluorescence turn-on substrate  PHYS.ORG · 6 days
Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels... more
Improving carbon-capturing with metal-organic frameworks  PHYS.ORG · 6 days
Metal-organic frameworks (MOFs) are versatile compounds hosting nano-sized pores in their crystal structure. Because of their nanopores, MOFs are now used in a wide range of applications, including separating petrochemicals, mimicking DNA, and removing heavy metals, fluoride anions,... more
CRISPR catches out critical cancer changes: New drug target for multiple cancers  SCIENCE DAILY · 6 days
In the first large-scale analysis of cancer gene fusions, researchers used CRISPR to uncover which gene fusions are critical for the growth of cancer... more
Breakthrough technique for studying gene expression takes root in plants  SCIENCE DAILY · 6 days
An open-source RNA analysis platform has been successfully used on plant cells for the first time -- a breakthrough that could herald a new era of fundamental research... more
New technique enables comprehensive genetic profiling of circulating tumor cells  NEWS MEDICAL · 6 days
A new way to cleanly separate out cancer cells from a blood sample enables comprehensive genetic profiling of the cancer cells, which could help doctors target tumors and... more
Activation of gene promoters: Scientists discover basis of regulatory specificity  PHYS.ORG · 6 days
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could... more
New technique for separation of cancer cells enables comprehensive genetic profiling  NEWS MEDICAL · 6 days
A new technique for obtaining cancer cells from blood samples without contamination from blood cells has made it feasible to conduct detailed genetic analysis of cancer... more
CRISPR uncovers which gene fusions are critical for growth of cancer cells  NEWS MEDICAL · 6 days
In the first large-scale analysis of cancer gene fusions, which result from the merging of two previously separate genes, researchers at the Wellcome Sanger... more
Britain's Genus signs deal to bring gene-edited pigs to China  REUTERS · 6 days
British livestock genetics firm Genus agreed on Thursday to license its know-how on virus-resistant pigs to... more
Blood test can assess effectiveness of treatment in patients with skin cancer  NEWS MEDICAL · 6 days
Blood tests that track the amount of tumor DNA can - after only one month of drug therapy - detect how well treatment is... more
Breakthrough technique for studying gene expression takes root in plants  PHYS.ORG · 6 days
An open-source RNA analysis platform has been successfully used on plant cells for the first time—a breakthrough that could herald a new era of fundamental research and bolster... more
Genomic collision may explain why many kidney transplants fail  SCIENCE DAILY · 6 days
Up to one in seven kidney donors and recipients may have a type of genetic incompatibility that leads to organ rejection, researchers have found. more
How cancer drug inhibits DNA repair in cancer cells  SCIENCE DAILY · 6 days
A cancer drug thought to be of limited use possesses a superpower of sorts: It is able to stop certain cancer cells from repairing their DNA in order to survive. more
Neanderthals and modern humans diverged at least 800,000 years ago, research on teeth shows  SCIENCE DAILY · 6 days
Neanderthals and modern humans diverged at least 800,000 years ago, substantially earlier than indicated by most DNA-based estimates, according to... more
[Research Articles] Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51  Science Magazine · 6 days
Combining the anti-angiogenic agent cediranib with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib improves progression-free survival compared to olaparib alone in ovarian cancer... more
[Editors' Choice] CuRBing cancers enthusiasm  Science Magazine · 6 days
A gene expression signature of biallelic RB1 loss identifies more aggressive tumors. more
[Research Articles] Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina  Science Magazine · 6 days
Retinal gene therapy with adeno-associated viral (AAV) vectors holds promises for treating inherited and noninherited diseases of the eye. Although clinical data... more
Neanderthals and modern humans diverged at least 800,000 years ago  PHYS.ORG · 6 days
Neanderthals and modern humans diverged at least 800,000 years ago, substantially earlier than indicated by most DNA-based estimates, according to new research by a UCL academic. more
Blood biopsy: New technique enables detailed genetic analysis of cancer cells  SCIENCE DAILY · 6 days
A new way to cleanly separate out cancer cells from a blood sample enables comprehensive genetic profiling of the cancer cells, which could help doctors target... more
Brazil seeks China's OK for genetically modified sugarcane  REUTERS · 6 days
Brazil's agriculture minister will ask Chinese officials on Thursday to greenlight exports to the Asian nation of sugar made from... more
Mutualistic interactions reshuffle the effects of climate change on plants across the tree of life  Science Magazine · 6 days
Climatically induced local species extinctions may trigger coextinction cascades, thus driving many more species to extinction than originally... more
PES1 is a critical component of telomerase assembly and regulates cellular senescence  Science Magazine · 6 days
Telomerase defers the onset of telomere shortening and cellular senescence by adding telomeric repeat DNA to chromosome ends, and its activation contributes to carcinogenesis.... more
ALBA protein complex reads genic R-loops to maintain genome stability in Arabidopsis  Science Magazine · 6 days
The R-loop, composed of a DNA-RNA hybrid and the displaced single-stranded DNA, regulates diverse cellular processes. However, how cellular R-loops are recognized remains poorly... more
Dental evolutionary rates and its implications for the Neanderthal-modern human divergence  Science Magazine · 6 days
The origin of Neanderthal and modern human lineages is a matter of intense debate. DNA analyses have generally indicated that both lineages diverged during the middle... more
Multiplexed single-cell RNA-seq via transient barcoding for simultaneous expression profiling of various drug perturbations  Science Magazine · 6 days
The development of high-throughput single-cell RNA sequencing (scRNA-seq) has enabled access to information about gene expression in individual cells and... more
Chewing gums reveal the oldest Scandinavian human DNA  SCIENCE DAILY · 6 days
The first humans who settled in Scandinavia more than 10,000 years ago left their DNA behind in ancient chewing gums, which are masticated lumps made from birch bark pitch. more
Software locates sugarcane genes of interest  PHYS.ORG · 6 days
Plants have larger and more complex genomes than all animals, be they mammals, birds, reptiles or amphibians. Fish are the exception to the rule. more
New doctors' DNA ages six times faster than normal in first year  SCIENCE DAILY · 6 days
Every summer, tens of thousands of newly minted doctors start the most intense year of their training: the first year of residency, also called... more
Researchers block protein that plays a key role in Alzheimer's disease  SCIENCE DAILY · 6 days
In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain. A study now shows... more
Many species could be even more likely to go extinct than we realise  PHYS.ORG · 6 days
More than a million species are at risk of extinction according to a new report on biodiversity. But even some species that... more
DNACRISPR
Peering into the past, scientists discover bacteria transformed a viral threat to survive
PHYS.ORG
Cryptic mutation is cautionary tale for crop gene editing
PHYS.ORG
DNA folds into a smart nanocapsule for drug delivery
PHYS.ORG
Using DNA templates to harness the sun's energy
PHYS.ORG
Digital cathedrals: bringing Notre-Dame de Paris back to life
PHYS.ORG
Scientists create first billion-atom biomolecular simulation
PHYS.ORG
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