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Four genes associated with OCD identified
NEWS MEDICAL There are found genes that have been identified to be associated with obsessive compulsive disorder (OCD). These genes have been found to alter the circuitry of the brain in a manner that could lead to OCD.... 1 hour
TGen project to develop standard operating procedures for single-cell RNA sequencing
NEWS MEDICAL The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation,... 3 hours
Resolving traffic jams in human ALS motor neurons
SCIENCE DAILY A team of researchers used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic... 5 hours
Tropical beetles face extinction threat
SCIENCE DAILY Climate change is putting many tropical high altitude beetles at risk of extinction, warn an international team of scientists. 5 hours
Genetic diversity plays major role in evolution of drug resistance
NEWS MEDICAL Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research... 7 hours
Scientists receive critical funding to study treatments for three deadly cancers
NEWS MEDICAL Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of... 10 hours
Yeast spotlights genetic variation's link to drug resistance
PHYS.ORG Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing... 12 hours
Tropical beetles face extinction threat
PHYS.ORG Climate change is putting many tropical high altitude beetles at risk of extinction, warn an international team of scientists. 13 hours
Search Of DNA In Dogs, Mice And People Finds 4 Genes Linked To OCD
NPR Scientists looking for genetic factors behind obsessive compulsive disorder looked for clues in the DNA of humans and two animal... 14 hours
Major advance in nanopore detection of peptides and proteins
SCIENCE DAILY Nanopore technology, which is used to sequence DNA, is cheap, hand-held and works in the jungle and in space. The use of this technology to identify peptides or proteins is... 15 hours
'Hiding in plain sight:' Discovery raises questions over scale of overlooked biodiversity
SCIENCE DAILY Scientists have used cutting edge DNA technology to demonstrate that one of Europe's top freshwater predators is actually two species rather than one. 15 hours
Proteins and polymers: Spinning strands hint at folding dynamics
SCIENCE DAILY Scientists have created flexible strings of magnetized beads to model how natural and synthetic strands bend and fold in dynamic conditions. The work could enhance knowledge of how proteins and... 15 hours
Novel mechanism of resistance to anti-cancer drugs
SCIENCE DAILY Investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings suggest a strategy for overcoming this resistance. 15 hours
Biology of childhood brain tumor subtypes offers clues to precision treatments
SCIENCE DAILY Researchers investigating pediatric low-grade gliomas (PLGG), the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with... 15 hours
Signaling pathway may be key to why autism is more common in boys
SCIENCE DAILY Researchers have discovered sex differences in a brain signaling pathway involved in reward learning and motivation that make male mice more vulnerable... 16 hours
Saving hearts after heart attacks: Overexpression of a gene enhances repair of dead muscle
SCIENCE DAILY Biomedical engineers report a significant advance in efforts to repair a damaged heart after a heart attack, using grafted heart-muscle... 16 hours
Matchmaking with consequences
PHYS.ORG Most human tumours have one thing in common: They harbour drastically increased amounts of the so-called Myc proteins. Animal experiments show that such high Myc concentrations contribute to causing cancer. But Myc proteins not only have harmful properties, they are... 16 hours
Study uses precision medicine approach to find effective treatments for rare cancers
NEWS MEDICAL For the first time, researchers have been able to identify effective treatments for patients with rare cancers by analyzing genes and proteins in their... 17 hours
Study sheds new light on why autism is more common in boys
NEWS MEDICAL Researchers aiming to understand why autism spectrum disorders (ASD) are more common in boys have discovered differences in a brain signaling pathway involved in... 17 hours
Researchers identify strategies to mitigate disturbed axonal transport in ALS patients
NEWS MEDICAL A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found... 17 hours
Key to expanding genetic code described
PHYS.ORG Yale scientists have described the atomic structure of a protein that is the key tool in efforts by synthetic biologists to expand the genetic code. 18 hours
Cascade of costs could push new gene therapy above $1 million per patient
NEWS MEDICAL Outrage over the high cost of cancer care has focused on skyrocketing drug prices, including the $475,000 price tag for the country's... 18 hours
'Hiding in plain sight'—Discovery raises questions over scale of overlooked biodiversity
PHYS.ORG Scientists have used cutting-edge DNA technology and museum samples collected over the past two centuries to reveal a new species of diving beetle living in streams... 21 hours
ESnet's science DMZ design could help transfer, protect medical research data
PHYS.ORG Like other sciences, medical research is generating increasingly large datasets as doctors track health trends, the spread of diseases, genetic causes of illness and the like.... 22 hours
Team uses magnetic beads to model microscopic proteins, polymers
PHYS.ORG An engineered string of micronwide beads may take up the slack where computer modeling fails researchers who study the bending, folding and other movements of polymers or biomolecules like actin... 22 hours
Novel gene expression signature assay could help enhance lymphoma management
NEWS MEDICAL Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide (nearly 40% of cases). Recent advancements indicate that both the prognosis... 24 hours
Columbia scientists receive grant from CZI to construct atlas of cells in human spinal cord
NEWS MEDICAL Scientists at Columbia's Zuckerman Institute today received a grant from the Chan Zuckerberg Initiative donor advised fund, an... 24 hours
CHOP researchers discover key differences among gene fusions in childhood brain tumors
NEWS MEDICAL Researchers investigating pediatric low-grade gliomas, the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine... 1 day
Scientists discover new non-genetic cause of resistance to anti-cancer therapies
NEWS MEDICAL The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States. 1 day
Einstein scientists share $9 million NIH grant for longevity research
NEWS MEDICAL Scientists now believe that the Fountain of Youth flows from our genes, or at least from the genes of people who live healthy lives to age 100 or... 1 day
An epigenetic key to unlock behavior change
PHYS.ORG When it comes to behaviour, researchers have moved beyond the "nature versus nurture" debate. It's understood that genes and environment both play a role. However, how they interact at a molecular level to shape... 1 day
Your Hair Color and Sleep Habits May Come from Neanderthals
LIVE SCIENCE Neanderthal DNA could influence your skin tone, hair color, sleep patterns, mood and even smoking behavior, a new study finds. 1 day
Researchers Uncover New Antibiotic Resistance Genes
SCI-NEWS.COM Chalmers University of Technology Professor Erik Kristiansson and co-authors have identified over 70 new metallo-β-lactamase genes that make bacteria resistant to last-resort antibiotics. “Metallo-β-lactamases... 1 day
Nidoviruses redundantly express genes and encode more proteins than previously believed, study finds
SCIENCE DAILY Arteriviruses, a family of single-stranded RNA viruses that belongs to the order Nidovirales, produce more proteins and messenger RNAs than previously reported,... 2 days
How cells induce inflammation upon detection of cytoplasmic DNA
SCIENCE DAILY A research team has elucidated the mechanism by which human cells induce inflammation upon detection of cytoplasmic DNA. Notably, the signal network involved differs from that used in the same... 2 days
Nidoviruses redundantly express genes and encode more proteins than previously believed, study finds
PHYS.ORG Arteriviruses, a family of single-stranded RNA viruses that belongs to the order Nidovirales, produce more proteins and messenger RNAs than previously reported,... 2 days
Scientists demonstrate path to linking the genome to healthy tissues, disease
SCIENCE DAILY A study has reached a major milestone in establishing a baseline understanding of gene expression across healthy human tissues, and linking genes to disease. 2 days
Major advance in nanopore detection of peptides and proteins
PHYS.ORG Nanopore technology, which is used to sequence DNA, is cheap, hand-held and works in the jungle and in space. The use of this technology to identify peptides or proteins is... 2 days
Fanged kangaroo research could shed light on extinction
SCIENCE DAILY Fanged kangaroos -- an extinct family of small fanged Australian kangaroos -- might have survived at least five million years longer than previously thought. A new study has found the species might... 2 days
Sleep duration may affect the integrity of sperm DNA
SCIENCE DAILY A new study found a link between sleep duration and a measure of chromosomal health in sperm. In the study of 2020 semen samples provided by 796 male volunteers from... 2 days
New antibiotic resistance genes found
SCIENCE DAILY Researchers have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA. 2 days
Structural insights into processes at DNA damage sites
PHYS.ORG Ishan Deshpande and his colleagues from the group of Susan Gasser and the Protein Structure Facility at the FMI elucidated the mechanism of how Mec1-Ddc2, a tumor suppressor involved in DNA damage... 2 days
Study finds link between sleep duration and measure of chromosomal health in sperm
NEWS MEDICAL A new study found a link between sleep duration and a measure of chromosomal health in sperm. The findings are published in... 2 days
Genome-wide data from a 40,000-year-old man in China reveals complicated genetic history of Asia
PHYS.ORG The biological makeup of humans in East Asia is shaping up to be a very complex story, with greater diversity... 2 days
Unexpected finding in the cell's power plant
PHYS.ORG Researchers at Karolinska Institutet have discovered that the protein complex RNase P in the cell's mitochondria behaves differently than previously thought. The findings, published in Nucleic Acids Research, give important new clues on how... 2 days
Medical News Today: How do genes and lifestyle choices affect lifespan?
MNT Researchers have analyzed abundant genetic and lifestyle data, and they warn that our lifestyle choices can have a serious impact on our life expectancy. 2 days
New antibiotic resistance genes found
PHYS.ORG Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA and the... 2 days
Researchers identify several previously unknown antibiotic resistance genes
NEWS MEDICAL Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. 2 days
Genes that determine skin color studied - new revelations
NEWS MEDICAL Human populations vary vastly in skin tones. European populations have been studied and some of the genes that determine skin color have been found. A latest study in a varied... 2 days
FDA advisory committee vote 16-0 for first even gene therapy for rare blindness
NEWS MEDICAL A panel of advisors to the United States Food and Drug Administration (FDA) has voted unanimously in favor of an experimental gene... 2 days
meet isolde where did it all begin Meet ISOLDE: Where did it all begin?
CERN Harriet Jarlett The ISOLDE control room in 1987, before the facility had to move to the new accelerator and site (Image: CERN)... 2 days
Medical News Today: Can psoriasis be passed on genetically?
MNT We examine the genetic factors affecting psoriasis. Learn more about the genes involved and what the studies say about skin conditions being hereditary. 4 days
Study provides insights into potential causes of spinal stenosis
NEWS MEDICAL A new study published in the Journal of Orthopaedic Research indicates that certain genetic changes are linked with an increased risk of developing lumbar spinal stenosis, a narrowing of the... 4 days
Newfoundland populated multiple times by distinct groups, DNA evidence shows
SCIENCE DAILY Researchers who've examined genetic evidence from mitochondrial DNA provide evidence that two groups of indigenous people in Canada, known as the Maritime Archaic and Beothuk, brought different matrilines... 4 days
Integrating networks and comparative genomics reveals retroelement proliferation dynamics in hominid genomes
Science Magazine Retroelements (REs) are mobile DNA sequences that multiply and spread throughout genomes by a copy-and-paste mechanism. These parasitic elements are active in diverse genomes,... 4 days
The sea cucumber genome points to genes for tissue regeneration
SCIENCE DAILY A new high-definition genome sequence of the sea cucumber provides molecular insights into its ability to regenerate. 4 days
Genetic clues to spinal stenosis
SCIENCE DAILY A new study indicates that certain genetic changes are linked with an increased risk of developing lumbar spinal stenosis, a narrowing of the open spaces in the lower spine that can lead to pain in the legs when... 4 days
New model predicts how E. coli bacteria respond to temperature changes, genetic mutations
NEWS MEDICAL Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond... 4 days
On the generation of solar spicules and Alfvenic waves
PHYS.ORG Combining computer observations and simulations, a new model shows that the presence of neutrals in the gas facilitates the magnetic fields to penetrate through the surface of the Sun producing... 5 days
New way to prevent genetically engineered and unaltered organisms from producing offspring
SCIENCE DAILY A major obstacle to applying genetic engineering to benefit humans and the environment is the risk that organisms whose genes have been altered might... 5 days
Scientists help show links between genes, body tissues
SCIENCE DAILY A research team is assessing how a person's genetic profile affects his body. The results could help show how individual genetic differences contribute to disease and guide treatments for heritable disorders such... 5 days
Restless legs syndrome study identifies 13 new genetic risk variants
SCIENCE DAILY A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition. 5 days
FDA experts offer a unanimous endorsement for pioneering gene therapy for blindness
Science Magazine Agency expected to announce its verdict on company’s gene therapy by early 2018 5 days
Medical News Today: New genetic risk factors for peanut and food allergy identified
MNT A new study finds that the gene EMSY is linked to a raised risk of peanut and food allergy, and that five... 5 days
Novel mechanism protects mitochondrial DNA
SCIENCE DAILY Researchers have discovered a novel mechanism safeguarding mitochondrial DNA. A central part of the protective mechanism is an unusual enzyme, PrimPol, which can re-initiate mitochondrial DNA replication after damage. 5 days
Study helps understand basic mechanisms of mitochondrial DNA maintenance
NEWS MEDICAL Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with... 5 days
How E. coli bacteria adapt under stress
SCIENCE DAILY Researchers have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations. The work sheds light on how cells adapt under environmental stress and has... 5 days
Model predicts how E. coli bacteria adapt under stress
PHYS.ORG Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations. The work... 5 days
Liquid biopsy for retinoblastoma
SCIENCE DAILY A new study provides proof of concept for a safe and effective way to derive genetic information from a retinoblastoma tumor. 5 days
DNA Study Finds No Evidence that Ancient Easter Islanders Intermixed with South Americans
SCI-NEWS.COM A new study of ancient DNA appears to rule out... 5 days
Fanged kangaroo research could shed light on extinction
PHYS.ORG Fanged kangaroos – an extinct family of small fanged Australian kangaroos – might have survived at least five million years longer than previously thought. 5 days
RIP Jeremy the lefty garden snail
PHYS.ORG A 'one in a million' mutant garden snail, who achieved international notoriety after a public appeal was launched to help find him a mate, has died. 5 days
How molecular riboswitches work in bacteria
PHYS.ORG Many bacteria have molecular control elements via which they can switch genes on and off. These riboswitches also open up new options in the development of antibiotics or the detection and decomposition of environmental toxins. Researchers... 5 days
Did Easter Islanders Have Early Contact with South Americans?
LIVE SCIENCE A new study of human bones found no trace of Native American DNA on the island. Debate over pre-European cultural mash-ups continues. 5 days
New study uncovers 13 previously-unknown genetic risk variants for restless legs syndrome
NEWS MEDICAL A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the... 5 days
Conservation cutbacks put Brazil's Amazon animals at risk
PHYS.ORG Benedito de Souza scoops back sand hiding a nest of baby giant Amazon River turtles that he had covered over weeks ago to hide from predators. Suddenly exposed, dozens of the tiny... 5 days
Head of Samsung's booming semiconductor business to resign
PHYS.ORG The chairman of Samsung Electronics Co.'s board of directors, who has been the public face of the company after its de facto chief was jailed on corruption charges, said Friday he will... 5 days
Researchers find multiple new mutations linked to autism in children but not their parents
NEWS MEDICAL Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the... 5 days
Surrogate liquid biopsy can provide genetic information about retinoblastoma tumors
NEWS MEDICAL Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age. If not diagnosed early, retinoblastoma may result in loss of one or... 5 days
How switches work in bacteria
SCIENCE DAILY Many bacteria have molecular control elements, via which they can switch on and off genes. These riboswitches also open up new options in the development of antibiotics or for the detection and decomposition of environmental toxins. Researchers have... 5 days
MIT researchers develop new technique to screen for genes that protect against diseases
NEWS MEDICAL Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect... 5 days
Whole genome sequencing could help better understand genetic abnormalities underlying autism
NEWS MEDICAL An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may... 5 days
Cellular reprograming implicated in model of Alzheimer's disease
MIT Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer's disease. 5 days
Evolution of skin color, taming rice thrice, and peering into baby brains
Science Magazine This week we hear stories about a new brain imaging technique for newborns, recently uncovered evidence on rice domestication on three continents, and why... 5 days
3D packaging of DNA regulates cell identity
SCIENCE DAILY The ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location... 5 days
Mitochondrial DNA could predict risk for sudden cardiac death, heart disease
SCIENCE DAILY The level, or 'copy number,' of mitochondrial DNA -- genetic information stored not in a cell's nucleus but in the body's energy-creating mitochondria -- is a... 5 days
Study documents gene mutation as cause of cancer form in the liver
NEWS MEDICAL There is no effective treatment for the cancer form found in the liver called fibrolamellar hepatocellular carcinoma, which is mainly found among children and... 5 days
FDA Panel Endorses Gene Therapy For A Form Of Childhood Blindness
NPR Food and Drug Administration advisers unanimously recommended that the agency approve the first gene therapy for an inherited disease — a rare defect that causes blindness... 5 days
Mystery surrounding ancient Easter Island people deepens
REUTERS WASHINGTON (Reuters) - The massive brooding stone figures peering from Easter Island's hillsides are emblematic of the enigmatic people who once thrived... 5 days
3-D packaging of DNA regulates cell identity
PHYS.ORG VIDEO The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down... 5 days
Unraveling the genetics of disc disease in dogs
SCIENCE DAILY Since the early 1900s, veterinarians have observed intervertebral disc disease -- a common cause of back pain, rear limb paralysis and inability to walk -- more frequently in dogs with short legs... 5 days
Star tortoise makes meteoric comeback
SCIENCE DAILY The Burmese star tortoise (Geochelone platynota), a medium-sized tortoise found only in Myanmar's central dry zone, has been brought back from the brink of extinction thanks to an aggressive captive-breeding effort spearheaded by a team of conservationists and... 5 days
Genes responsible for diversity of human skin colors identified
SCIENCE DAILY A study of diverse African groups by geneticists has identified new genetic variants associated with skin pigmentation. The findings help explain the vast range of skin color on the African... 5 days
Criminal offenders with genetic mental disorders judged more negatively
SCIENCE DAILY Popular literature and crime dramas imply that defense attorneys who portray their clients as victims may have better outcomes. The belief is that jurors assign less blame to defendants they... 5 days
New gene variants reveal the evolution of human skin color
Science Magazine Some of the mutations responsible for lighter skin in Europeans turn out to have an ancient African origin 5 days
Loci associated with skin pigmentation identified in African populations
Science Magazine Despite the wide range of skin pigmentation in humans, little is known about its genetic basis in global populations. Examining ethnically diverse African genomes, we identify variants in or near... 5 days
The sea cucumber genome points to genes for tissue regeneration
PHYS.ORG A new high-definition genome sequence of the sea cucumber provides molecular insights into its ability to regenerate, according to a new study publishing 12 October in the open... 5 days
Cause of cancer form in the liver identified
SCIENCE DAILY Researchers have identified the two genes whose mutation cause a serious cancer form found in the liver. The result sets concrete goals for future treatment of the otherwise incurable disease. 5 days
Whole genome sequencing identifies new genetic signature for autism
SCIENCE DAILY An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful... 5 days
Study Identifies New Gene Variation Associated with Increased Risk of Nicotine Addiction
SCI-NEWS.COM Europeans and European/African Americans with a variant of the DNA Methyltransferase 3 Beta (DNMT3B) gene have an increased risk of developing nicotine dependence, smoking... 5 days
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3-D packaging of DNA regulates cell identity
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Watch the human genome fold itself in four dimensions
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