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Genetic study uncovers fungal sex secrets, which shed light on candidiasis
SCIENCE DAILY A new genetic analysis of fungal yeast infections (candidiasis) from around the world has revealed surprising secrets about how these microbes reproduce and cause disease, according... 2 days
Distinct human mutations can alter the effect of medicine
SCIENCE DAILY About one third of all medicine binds to the same type of receptor in the human body. An estimated three percent of the population have receptors of this type that... 2 days
Genetic instructions from mom set the pattern for embryonic development
SCIENCE DAILY A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from... 2 days
New genetic analysis of candidiasis reveals surprising fungal sex secrets
NEWS MEDICAL Working together with researchers in the Université Paris-Sud in France and University Medical Centre Göttingen in Germany, ICREA Research Professor Toni Gabaldón and his team at the Centre... 2 days
Medical News Today: Breast cancer: These gene variations may shorten young women's survival
MNT New research finds that young women with early-onset breast cancer possess variations in a specific gene that might affect their survival. 2 days
Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup
NEWS MEDICAL Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the... 2 days
Genetic instructions from mom set the pattern for embryonic development
PHYS.ORG A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from... 2 days
Medical News Today: Hemophilia cure? Gene therapy trial shows dramatic results
MNT A year after gene therapy treatment, people with hemophilia A are showing normal levels of clotting factor and big reductions in bleeding. 2 days
Cancer immunotherapy may work better in patients with specific genes
SCIENCE DAILY Investigators have been trying to understand why and have recently found how an individual's own genes can play a role in the response to the immunotherapy drugs. 3 days
Rare gene mutation gives rise to low sensitivity to pain
NEWS MEDICAL Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by... 3 days
Researchers examine link between tumor mutational burden and response to immune checkpoint therapy
NEWS MEDICAL Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome. 3 days
Epigenetic rheostat uncovers how gene regulation is inherited and maintained
PHYS.ORG While our genome contains a vast repertoire of genes that are responsible for virtually all of the cellular and developmental processes life requires, it is the complex dance... 3 days
Corn genetics provides insight into the crop's historical spread across the Americas
PHYS.ORG VIDEO Iowa State University scientists have taken a journey through the past by studying the genetic changes in corn brought about by domestication. 3 days
Nanoparticles as a possible solution to antibiotic resistance
PHYS.ORG Around one in 3,300 children in Germany is born with mucoviscidosis. A characteristic of this illness is that one channel albumen on the cell surface is disturbed by mutations. Thus, the amount... 3 days
Medicare fails to recover hundreds of millions of dollars in lab overcharges
NEWS MEDICAL Five years ago, Companion DX Reference Lab hoped to cash in on cutting-edge genetic tests paid for by Medicare. 3 days
Medical News Today: Need more sleep than most people? Blame your genes
MNT Do you need 12 hours of sleep per day to function? Or is 2 hours per night enough for you? A new study investigates... 3 days
Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer
NEWS MEDICAL A new study led by scientists at the University of Southampton has found that inherited variation... 3 days
Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun
NEWS MEDICAL A fusion gene is a single composite gene that is the result of the combination of two formerly... 3 days
How defeating THOR could bring a hammer down on cancer
SCIENCE DAILY Researchers have uncovered a novel gene they named THOR. It's a highly conserved long non-coding RNA that plays a role in cancer development. Knocking it out can halt... 3 days
To sleep or not: Researchers explore complex genetic network behind sleep duration
SCIENCE DAILY Scientists have identified differences in a group of genes they say might help explain why some people need a lot more sleep -- and... 3 days
Genetic variations may help identify people at high-risk for chronic pain after surgery
NEWS MEDICAL Genetics may play a role in determining whether patients experience chronic pain after surgery, suggests a study published today in the Online... 3 days
Couples win lawsuit over donated eggs with genetic defect
ABC NEWS Two couples that gave birth to children with a genetic defect later traced to donated eggs have won a lawsuit against a New York fertility doctor and his clinic 3 days
To sleep or not: Researchers explore complex genetic network behind sleep duration
PHYS.ORG Scientists have identified differences in a group of genes they say might help explain why some people need a lot more sleep—and others less—than... 3 days
How to survive a mass extinction
Science Magazine 3 days
Eudicot plant-specific sphingolipids determine host selectivity of microbial NLP cytolysins
Science Magazine Necrosis and ethylene-inducing peptide 1–like (NLP) proteins constitute a superfamily of proteins produced by plant pathogenic bacteria, fungi, and oomycetes. Many NLPs are cytotoxins that facilitate microbial infection... 3 days
Enzyme-free nucleic acid dynamical systems
Science Magazine Chemistries exhibiting complex dynamics—from inorganic oscillators to gene regulatory networks—have been long known but either cannot be reprogrammed at will or rely on the sophisticated enzyme chemistry underlying the central dogma. Can simpler molecular mechanisms, designed from scratch,... 3 days
Medical News Today: Silencing 'junk' gene could halt tumor growth
MNT Researchers have found that a gene they call THOR produces a long, non-coding RNA that has a role in cancer, and whose silencing stops tumor growth. 3 days
Synthetic protein packages its own genetic material and evolves
SCIENCE DAILY Scientists have created computationally designed protein assemblies, that display some functions normally associated with living things, in the search for ways to transport therapeutic cargo into specific types of cells... 3 days
Frequent sun exposure may cue gene fusion found in skin cancer
SCIENCE DAILY Researchers have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to... 3 days
Ancient genetic mutation helps explain origin of some human organs
SCIENCE DAILY A genetic mutation that occurred over 700 million years ago may have contributed to the development of certain organs in human beings and other vertebrates. This change, a... 3 days
DNA: Supercoiling pushes molecular handcuffs along chromatin fibres
SCIENCE DAILY As it squeezes down the chromatin fiber, the cohesin protein complex extrudes a growing loop of DNA -- a bit like the quick-lacing system of trail-running shoes. But what is powering the... 3 days
How a gene mutation could help to treat chronic pain
MNT Researchers suggest that a rare gene mutation that causes insensitivity to pain could be utilized to uncover new treatments for chronic pain. 3 days
Medical News Today: How a gene mutation could help to treat chronic pain
MNT Researchers suggest that a rare gene mutation that causes insensitivity to pain could be utilized to uncover new treatments for chronic pain. 3 days
Genetic mutation explains the origin of some human organs
PHYS.ORG A neutral genetic mutation—a fluke in the evolutionary process that had no apparent biological purpose—that appeared over 700 million years ago in biological evolution could help explain the origin of... 4 days
Supercoiling pushes molecular handcuffs along chromatin fibres
PHYS.ORG Gene regulation relies on complex structural arrangements and processes at the molecular level. One of them, called 'chromatin loop extrusion', strikingly resembles the quick-lacing system of some trail running shoes: as the buckle is... 4 days
Groundbreaking gene therapy trial set to cure hemophilia
SCIENCE DAILY A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial. 4 days
A new way to deliver mRNA genomes: Nucleocapsids with evolutionary properties
PHYS.ORG (Phys.org)—A team of researchers at the University of Washington has created microscopic assemblies for packaging genetic material that they call synthetic nucleocapsids. The team hopes the... 4 days
Fungus relies on bacteria to regulate key components of its reproductive machinery
PHYS.ORG To better understand how beneficial organisms (symbionts) are transmitted between host generations, researchers investigated the role of bacterial that lives within its host (endosymbionts)... 4 days
Designer proteins that package genetic material could help deliver gene therapy
PHYS.ORG If you've ever bought a new iPhone, you've experienced good packaging. 4 days
New blood test accurately forecasts advanced heart failure patients’ survival after surgery
NEWS MEDICAL An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for... 4 days
BigH1—the key histone for male fertility
PHYS.ORG Researchers in the Chromatin Structure and Function Lab at the Institute for Research in Biomedicine (IRB Barcelona) have identified the histone BigH1 as a key protein in stem cell differentiation to male sex cells. Histones are... 4 days
Medical News Today: What is Treacher Collins syndrome?
MNT Learn about Treacher Collins syndrome, a genetic disorder that affects how the bones and tissues in the face develop. We look at its causes and treatments. 4 days
Groundbreaking gene therapy trial brings cure for hemophilia closer
NEWS MEDICAL A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial led by the NHS in London. 4 days
20% of young colon cancer patients have inherited genetic abnormality, research finds
NEWS MEDICAL As doctors grapple with increasing rates of colorectal cancers in young people, new research from the University of Michigan may offer some insight into... 4 days
Targeted lung cancer treatments may benefit smokers and non-smokers alike
NEWS MEDICAL Smokers are less likely than non-smokers to have lung cancers caused by targetable genetic changes. But a study published this week in the journal Clinical Cancer Research shows... 4 days
CRISPR gene editing moved into new territory in 2017
SCIENCE-NEWS Scientists edited viable human embryos with CRISPR/Cas9 this year. 4 days
The toxic sugar tree: Mapping the evolutionary history of a cancerous sugar gene
PHYS.ORG Around two million years ago, a genetic change occurred that differentiated humans from most other primates that both protected humans from diseases,... 4 days
Genetic study defies 'one-size-fits-all' approach to prescribing opioids for chronic pain
SCIENCE DAILY Researchers are assessing clinical and genetic characteristics of a large patient cohort suffering from chronic musculoskeletal pain and receiving prescription opioids. With this information, the multidisciplinary... 4 days
Immune cells turn back time to achieve memory
SCIENCE DAILY What distinguishes memory CD8 T cells from untrained naive cells is that they can respond rapidly, within minutes or hours. The new research illuminates how they do it -- their genes are... 4 days
A Triassic plesiosaurian skeleton and bone histology inform on evolution of a unique body plan
Science Magazine Secondary marine adaptation is a major pattern in amniote evolution, accompanied by specific bone histological adaptations. In the... 4 days
[Reports] Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel
Science Magazine The AAA+ adenosine triphosphatase (ATPase) Thorase plays a critical role in controlling synaptic plasticity by regulating... 4 days
Reprogramming bacteria instead of killing them could be the answer to antibiotic resistance
PHYS.ORG Changing someone's genetic programming is easier than you might think. While techniques for altering DNA at the molecular level are becoming more... 4 days
Even wild mammals have regional dialects
PHYS.ORG Researchers from Cardiff University's Otter Project have discovered that genetically distinct populations of wild otters from across the UK have their own regional odours for communicating vital information to each other. The findings could have implications... 5 days
Colliding neutron stars, gene editing, human origins and more top stories of 2017
SCIENCE-NEWS A gravitational wave discovery is the year's biggest science story — again. 5 days
CRISPR gene editing moved into humans in 2017
SCIENCE-NEWS Scientists edited viable human embryos with CRISPR/Cas9 this year. 5 days
Approval of gene therapies for two blood cancers led to an ‘explosion of interest’ in 2017
SCIENCE-NEWS The first gene therapies approved in the United States are treating patients with certain types of... 5 days
Researchers report findings about the control of cell division
PHYS.ORG Experts from the University of Seville and the Andalusian Centre for Molecular Biology and Regenerative Medicine (Cabimer) have published a new study on the mechanisms that regulate cell division and... 5 days
Genetic Analysis and Bio-Rad enter into supply and distribution agreement for GA-map clinical test
NEWS MEDICAL Genetic Analysis and Bio-Rad Laboratories, Inc., a global provider of life science research and clinical diagnostic products, today announced that... 5 days
New study explains why one identical twin more at risk for autoimmune diseases
NEWS MEDICAL It does not matter if you raise them the same, feed them the same, or dress them the same, any parent with... 5 days
Important new aspects are revealed about the control of cell division
SCIENCE DAILY Experts have published a new study on the mechanisms that regulate cell division and guarantee the correct distribution of chromosomes during this process. In particular, they... 5 days
Using 3D cell cultures to fight anti-cancer therapy resistance
SCIENCE DAILY An international research team has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer.... 5 days
Privacy policies affect quantity of genetic testing
SCIENCE DAILY Different types of privacy laws in US states produce markedly different effects on the willingness of patients to have genetic testing done, according to a new study. 5 days
DNA element may cause rare movement disorder
SCIENCE DAILY A team of researchers has identified a specific genetic change that may be the cause of a rare but severe neurological disorder called X-linked dystonia parkinsonism. 5 days
Genetics preserves traces of ancient resistance to Inca rule
SCIENCE DAILY The Chachapoyas region was conquered by the Inca Empire in the late 15th century. Inca oral histories, written down after the Spanish conquest, claim that the native population was forcibly... 5 days
Researchers reveal pathological mechanisms in congenital myotonic dystrophy
NEWS MEDICAL Myotonic dystrophy (DM) is the most common form of genetic muscular dystrophy that begins in adulthood. DM is characterized by progressive muscle wasting and weakness. People with this disorder often have prolonged... 5 days
DNA Reveals that Silky Anteaters Are Seven Species
SCI-NEWS.COM The silky anteater (Cyclopes didactylus) has previously been recognized to be a single species divided into several sub-species. But a... 5 days
For women with genetic risk, semi-annual MRI beats mammograms
SCIENCE DAILY Intensive surveillance including a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exam every six months was far more effective in detecting breast cancer in younger women with a high-risk genetic profile... 5 days
African genetic diversity to unlock disease susceptibility
SCIENCE DAILY Scientists have sequenced the genetic makeup of 24 South African individuals of different ethnolinguistic origins. The first government-funded human genomics research study performed on African soil, aimed at unlocking the unique genetic character of... 5 days
Immune diseases inflict identical twins differently
SCIENCE DAILY A new study reports which epigenetic factors in certain chromosomes that make one twin more at risk for autoimmune thyroid diseases. 5 days
WATCH: Family fights to find a cure after 2 children are diagnosed with fatal genetic disease
ABC NEWS A New York couple is calling on the pubic's help to raise awareness and funding for... 6 days
Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium
NEWS MEDICAL Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced new results from two studies... 6 days
Hidden genes hold blueprints for designing new anti-cancer drugs
NEWS MEDICAL New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds. 6 days
Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease
NEWS MEDICAL Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To... 6 days
Medical News Today: What you should know about white hair
MNT A look at white hair, a common change that many people experience as they age. Included is detail on genetic factors and stress-related causes. 6 days
Lack Of Genetic Diversity May Have Doomed Tasmanian Tiger, Scientists Say
NPR Although humans are blamed for the extinction of the dog-like Australian marsupial some 80 years ago, researchers say its problems may have started more than 70,000... 6 days
Searching for the CRISPR Swiss-army knife
PHYS.ORG VIDEO Scientists at the University of Copenhagen, led by the Spanish Professor Guillermo Montoya, are investigating the molecular features of different molecular scissors of the CRISPR-Cas system to shed light on the so-called "Swiss-army knives" of genome... 6 days
Genetics preserves traces of ancient resistance to Inca rule
PHYS.ORG The Chachapoyas region was conquered by the Inca Empire in the late 15th century. Knowledge of the fate of the local population has been based largely on Inca oral histories,... 6 days
Tasmanian tiger doomed long before humans came along
PHYS.ORG The Tasmanian tiger was doomed long before humans began hunting the enigmatic marsupial, scientists said Tuesday, with DNA sequencing showing it was in poor genetic health for thousands of years before its... 6 days
Huntington's disease drug clears initial hurdles - raising hopes
NEWS MEDICAL Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the... 6 days
For women with genetic risk, bi-annual MRI beats mammograms
SCIENCE DAILY Intensive surveillance including a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exam every six months was far more effective in detecting breast cancer in younger women with a high-risk genetic profile... 6 days
Medical News Today: How inhibiting one protein could help to treat pancreatic cancer
MNT Targeting SUV420H2 may increase treatment response as the enzyme silences genes that stop pancreatic cancer cells morphing into a more aggressive state. 6 days
Is there really a covert manipulation of U.N. discussions about regulating gene drives?
Science Magazine Dangerous lack of transparency, critics say. Meaningless flap, say the criticized 6 days
Blueprints for anti-cancer drugs discovered in bacterial genomes
PHYS.ORG Scientists on the Florida campus of The Scripps Research Institute (TSRI) who had previously discovered the prostate cancer-killing compound LNM E1 have now brought the family of LNM molecules even closer to... 6 days
Patients' individual genomes may affect efficacy, safety of gene editing
SCIENCE DAILY Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people's cells, and multiple trials are recruiting or... 6 days
Patients' individual genomes may affect efficacy, safety of gene editing
PHYS.ORG Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people's cells, and multiple trials are recruiting or... 6 days
How much can 252-million-year-old ecosystems tell us about modern Earth? A lot
SCIENCE DAILY During the late Permian, the equator was dry and desert-like, yet surprisingly a hotspot for biodiversity, new paleontological research shows. Similarly to modern rainforests,... 6 days
Large genetic study links tendency to undervalue future rewards with ADHD, obesity
SCIENCE DAILY Researchers have found a genetic signature for delay discounting -- the tendency to undervalue future rewards -- that overlaps with attention-deficit/hyperactivity disorder (ADHD), smoking... 6 days
Dolphin, bear studies have paved the way to improved population forecasting
SCIENCE DAILY A new article challenges the validity of current methods for forecasting the persistence of slow-growing species for conservation purposes, and provides a better approach to reducing... 6 days
Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer
NEWS MEDICAL An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures... 6 days
New study identifies genetic basis for western corn rootworm resistance in maize
PHYS.ORG Farmers are stuck. Western corn rootworm can destroy cornfields - and profits - but populations of the "billion-dollar bug" have stopped responding to insecticides... 6 days
Study: Diet Success Depends on Your Genes
SCI-NEWS.COM A diet that makes one individual lean and healthy might have the complete opposite effect on another, according to a new study... 7 days
Dolphin and bear studies pave the way to improved population forecasting
PHYS.ORG A new article by a UNSW Sydney-led team challenges the validity of current methods for forecasting the persistence of slow-growing species for conservation purposes, and provides... 7 days
St. Jude gene therapy offers hope for infants with 'bubble boy' disease
NEWS MEDICAL Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune... 7 days
New genetic model identified for predicting outcomes in patients with primary myelofibrosis
NEWS MEDICAL A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients... 7 days
New genetic model identified for predicting outcomes in patients primary myelofibrosis
NEWS MEDICAL A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary... 7 days
Bi-annual MRI beats mammograms in detecting breast cancer among women with genetic risk
NEWS MEDICAL Intensive surveillance including a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exam every six months was far more effective in detecting breast cancer... 7 days
Chromosomes: Definition & Structure
LIVE SCIENCE Chromosomes carry hereditary information for everything from height to eye color. 1 week
Simple molecular test may help predict presence of high-grade pancreatic cancers
NEWS MEDICAL A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and... 1 week
PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations
NEWS MEDICAL In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center,... 1 week
Corn genetics provides insight into the crop's historical spread across the Americas
PHYS.ORG
Searching for the CRISPR Swiss-army knife
PHYS.ORG
Scientists modify CRISPR to epigenetically treat diabetes, kidney disease, muscular dystrophy
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