DNA
Early DNA lineages shed light on the diverse origins of the contemporary population  SCIENCE DAILY · 9 hours
A new genetic study demonstrates that, at the end of the Iron Age, Finland was inhabited by separate and differing populations, all... more
Lichens are way younger than scientists thought  SCIENCE DAILY · 9 hours
Lichens -- a combo of fungus and algae -- can grow on bare rocks, so scientists thought that lichens were some of the first organisms to make their way onto land from the water,... more
DNA may hold the clue to protecting endangered species  PHYS.ORG · 11 hours
A new method for analyzing DNA collected from waterways which can help identify endangered bird species has been developed with the help of researchers from The University of Western Australia. more
eDNA reveals where endangered birds of a feather flock together  PHYS.ORG · 9 hours
For the first time, Australian scientists have shown that environmental DNA (eDNA) can be used to detect the presence of an endangered bird species simply by collecting a... more
A potential new way to diagnose male infertility and pharmaceutical treatment options  SCIENCE DAILY · 12 hours
New research has discovered infertile men have identifiable patterns of epigenetic molecules or biomarkers attached to their sperm DNA that aren't present in fertile... more
Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions  NEWS MEDICAL · 22 hours
One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding... more
DNA data offers scientific look at 500 years of extramarital sex in Western Europe  SCIENCE DAILY · 1 day
Researchers have put DNA evidence together with long-term genealogical data to explore questions of biological fatherhood on a broad scale... more
Observing changes in the chirality of molecules in real time  PHYS.ORG · 1 day
Some molecules can exist in two mirror-image forms, similar to our hands. Although such so-called enantiomers have almost identical physical properties, they are not the same. The fact... more
DNA data offers scientific look at 500 years of extramarital sex in Western Europe  PHYS.ORG · 1 day
These days it's easy to resolve questions about paternity with over-the-counter test kits. Now, researchers have put DNA evidence together... more
Researchers unravel protective properties of telomere t-loops  SCIENCE DAILY · 2 days
Loops at the ends of telomeres play a vital protective role preventing damage to chromosomes, according to new research. The study showed how the winding and unwinding of 't-loops' at the end of telomeres... more
Predicting evolution: Not just 'survival of the fittest'  SCIENCE DAILY · 2 days
A new method of 're-barcoding' DNA allows scientists to track rapid evolution in yeast. The approach has implications for the prediction of dominant viral strains. more
The post-PAM interaction of RNA-guided spCas9 with DNA dictates its target binding and dissociation  Science Magazine · 2 days
Cas9 is an RNA-guided endonuclease that targets complementary DNA for cleavage and has been repurposed for many biological usages. Cas9... more
Leukemia type B cell can transform into a macrophage through epigenetic changes  NEWS MEDICAL · 2 days
All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects. more
DNA Just One of More Than 1 Million Possible 'Genetic Molecules,' Scientists Find  LIVE SCIENCE · 4 days
Scientists used a computer program to uncover more than 1 million molecules that could potentially store genetic information, just like DNA. more
DNA is only one among millions of possible genetic molecules  SCIENCE DAILY · 4 days
Biology encodes information in DNA and RNA, complex molecules finely tuned to their functions. Although, other nucleic acid-like polymers are known, yet much remains unknown regarding possible alternatives... more
DNA is only one among millions of possible genetic molecules  nanowerk · 5 days
Scientists computed a zoo of millions of alternate genetic polymer molecular structures, giving context for why biology encodes information how it does, and providing potential leads for new... more
DNA SOS: Understanding DNA signaling pathways  PHYS.ORG · 4 days
When cells suffer DNA damage, they send out an SOS signal. When the repair crew arrives, the emergency signal is cancelled as it is no longer needed. This two-stage process is an important one in many... more
DNA is only one among millions of possible genetic molecules  PHYS.ORG · 4 days
Biology encodes information in DNA and RNA, which are complex molecules finely tuned to their functions. But are they the only way to store hereditary molecular information? Some... more
Synthetic DNA technology applied as a novel strategy for delivery of anti-HIV antibodies  nanowerk · 6 days
Synthetic DNA-encoded monoclonal antibodies (DMAbs) allow for in vivo production of broadly neutralizing antibodies in preclinical studies. more
DNA technology as a novel strategy for delivery of anti-HIV antibodies  SCIENCE DAILY · 1 week
Scientists applied synthetic DNA-based technology to drive in vivo production of broadly neutralizing anti-HIV antibodies in small and large-animal models, providing proof of concept for a... more
Neural network fills in data gaps for spatial analysis of chromosomes  SCIENCE DAILY · 1 week
Computational methods used to fill in missing pixels in low-quality images or video also can help scientists provide missing information for how DNA is organized in... more
Neural network fills in data gaps for spatial analysis of chromosomes  PHYS.ORG · 1 week
Computational methods used to fill in missing pixels in low-quality images or video also can help scientists provide missing information for how DNA is organized in... more
Feast or famine: Scientists find key bio 'switch' that helps cells adapt  SCIENCE DAILY · 1 week
Scientists have found that a chemical mark on histones - a key protein involved in the function of our DNA - occurs naturally under... more
SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy  Science Magazine · 1 week
A homozygous mutation of human tyrosyl-DNA phosphodiesterase 1 (TDP1) causes the neurodegenerative syndrome, spinocerebellar ataxia with axonal neuropathy (SCAN1). TDP1 hydrolyzes the phosphodiester bond between DNA 3'-end and... more
Lost pup turns out to be a rare purebred dingo  PHYS.ORG · 1 week
He's furry, playful, and has puppy eyes. It's little wonder Wandi was mistaken for a dog when he was found in an Australian backyard—but DNA testing has confirmed... more
Scientists discover cell protein crucial in preventing viral replication  NEWS MEDICAL · 1 week
A research team has discovered a protein without which cells infected by viruses cannot trigger an immune response, leading to 100% mortality with even non-disease-producing strains. The discovery of the... more
Researchers find genes from 'fossil' virus in human DNA to be active  NEWS MEDICAL · 1 week
Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and... more
The evolution of genetic engineering  PHYS.ORG · 1 week
Charles Gersbach, the Rooney Family Associate Professor of Biomedical Engineering at Duke University, leads a lab that is centered on developing and applying genome engineering tools––most notably CRISPR-based technology. CRISPR-Cas is a bacterial defense system that allows bacteria... more
Study of African animals illuminates links between environment, diet and gut microbiome  PHYS.ORG · 2 weeks
In recent years, the field of microbiome research has grown rapidly, providing newfound knowledge—and newfound questions—about the microbes that inhabit human and animal bodies.... more
Online tool speeds response to elephant poaching by tracing ivory to source  SCIENCE DAILY · 2 weeks
A new tool uses an interactive database of geographic and genetic information to quickly identify where the confiscated tusks of African elephants were originally... more
Potential genetic markers of multiple sclerosis severity  SCIENCE DAILY · 2 weeks
In a bid to determine factors linked to the most debilitating forms of multiple sclerosis (MS), researchers say they have identified three so-called 'complement system' genes that appear to play a role in MS-caused... more
Mechanisms preserving cell identity are based on status of proteins housing DNA  NEWS MEDICAL · 2 weeks
The inheritance, not only of DNA, but of changes to proteins that package it, maintains the identity of cells as they multiply, a new... more
Mutated form of DNA repair protein may shed light on its role in preventing cancer  SCIENCE DAILY · 2 weeks
Researchers created a mutated version of RAD51, a DNA repair protein, to better understand its critical functions at... more
Mutated version of DNA repair protein may illuminate its role in preventing cancer  NEWS MEDICAL · 2 weeks
Two trillion times each day, the cells in a typical human divide to replace old, damaged or dead cells. Before a cell... more
Status of proteins housing DNA controls how cells maintain identity  PHYS.ORG · 2 weeks
The inheritance, not only of DNA, but of changes to proteins that package it, maintains the identity of cells as they multiply, a new study finds. more
Analyzing gut bacteria more accurately to make diagnosis  PHYS.ORG · 2 weeks
The microorganisms in our intestines could be linked to certain diseases such as Alzheimer's and diabetes. Researchers from the AD-gut consortium have developed a novel method—combining optical DNA mapping and statistics—for accurately... more
Liquid biopsy can predict prognosis in patients with glioblastoma  NEWS MEDICAL · 2 weeks
A blood test that measures the amount of cell-free DNA (cfDNA) in the bloodstream - called a liquid biopsy - correlates with how patients will progress after they are diagnosed... more
Genetic history of endangered Australian songbird could inspire an encore  SCIENCE DAILY · 2 weeks
The genetic history of a critically endangered songbird shows its best chance of survival is to protect its rapidly disappearing habitat. Researchers used DNA samples from museums around... more
Crab disease poses threat to shellfish stocks  SCIENCE DAILY · 2 weeks
Shore crabs carry parasites that pose a major threat to shellfish stocks. In a new study, researchers have used several different detection methods, including taking DNA from seawater, to build up the first comprehensive... more
Crab disease poses threat to shellfish stocks  PHYS.ORG · 2 weeks
Shore crabs carry parasites that pose a major threat to shellfish stocks. In a new study, Swansea University researchers have used several different detection methods, including taking DNA from seawater, to build up the... more
Advanced microscopy reveals unusual DNA structure  PHYS.ORG · 2 weeks
An advanced imaging technique reveals new structural details of S-DNA, ladder-like DNA that forms when the molecule experiences extreme tension. This work conducted at Sandia National Laboratories and Vrije University in the Netherlands provides the first... more
In one direction or the other: That is how DNA is unwound  PHYS.ORG · 2 weeks
Joining computer simulations and lab experiments, an international research group sheds light on one of the key mechanisms of cell life. more
Scientists modify a toxic protein to create a biosensor  NEWS MEDICAL · 2 weeks
Researchers have shown that the pore-forming toxin (PFT), aerolysin, could be used as a biosensor in the sequencing of DNA and proteins. more
Detection dogs and DNA on the trail of endangered lizards  SCIENCE DAILY · 2 weeks
Detection dogs trained to sniff out the scat of an endangered lizard in California's San Joaquin Valley, combined with genetic species identification, could represent a new noninvasive sampling... more
Detection dogs and DNA on the trail of endangered lizards  PHYS.ORG · 2 weeks
Detection dogs trained to sniff out the scat of an endangered lizard in California's San Joaquin Valley, combined with genetic species identification, could represent a new noninvasive sampling... more
Major U.K. genetics lab accused of misusing African DNA  Science Magazine · 2 weeks
Sanger Institute’s aborted effort to develop gene chip could set back research in Africa more
DNA sequences encode information in many different ways  NEWS MEDICAL · 2 weeks
DNA sequences encode information in many different ways. Codons specify the amino acids involved in making a protein. more
Re-cracking the genetic code  PHYS.ORG · 2 weeks
Crack open a biology textbook and you will find the table summarizing the standard genetic code. This refers to the set of rules by which the cell "decodes" the information contained in DNA and "translates" it into the amino acids... more
Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models  NEWS MEDICAL · 2 weeks
Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating... more
Researchers reconstruct the evolutionary history of metabolism  NEWS MEDICAL · 2 weeks
By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks - which drive every cellular process from protein building to DNA... more
Turning a dangerous toxin into a biosensor  nanowerk · 2 weeks
Some bacteria release a toxin that forms pores on other cells. Scientists have studied the pore-forming toxin aerolysin and genetically engineered it to be used as a high-resolution sensor for biological molecules like DNA... more
Turning a dangerous toxin into a biosensor  SCIENCE DAILY · 2 weeks
Some bacteria release a toxin that forms pores on other cells. Scientists have studied the pore-forming toxin aerolysin and genetically engineered it to be used as a high-resolution sensor for biological molecules like DNA... more
Some types of proteins can stabilize damaged DNA  NEWS MEDICAL · 3 weeks
At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn... more
Transforming DNA repair errors into assets  SCIENCE DAILY · 3 weeks
A new bioinformatics tool, MHcut reveals that a natural repair system for DNA damage, microhomology-mediated end joining, is probably far more common in humans than originally assumed. Using MHcut and commercial genome-editing technology, the researchers created... more
Study tracks evolutionary history of metabolic networks  PHYS.ORG · 3 weeks
By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein building to DNA repair—became less... more
Advanced cancer drug shrinks and intercalates DNA  SCIENCE DAILY · 3 weeks
A new study has found that the drug first forces itself between the strands of the DNA molecule's double helix, prying them apart. It then compacts the structures by partially neutralizing their phosphate backbones. more
Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered  NEWS MEDICAL · 3 weeks
Recently, a drug named Pixantrone (PIX) was developed, which is far less damaging to the heart than previous, less advanced compounds. PIX is now used to treat cancers... more
'Protein-scaffolding' for repairing DNA damage  SCIENCE DAILY · 3 weeks
Researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired defects in certain proteins cannot keep their DNA stable... more
Transforming DNA repair errors into assets  PHYS.ORG · 3 weeks
A new bioinformatics tool, MHcut, developed by researchers in Kyoto, Japan, and Montreal, Canada, reveals that a natural repair system for DNA damage, microhomology-mediated end joining, is probably far more common in humans than originally assumed.... more
Gold-DNA nanosunflowers for efficient gene silencing and controlled transformation  PHYS.ORG · 3 weeks
Developing an efficient delivery system for enhanced and controlled gene interference-based therapeutics is an existing challenge in molecular biology. The advancing field of nanotechnology can provide an effective, cross-disciplinary strategy... more
Completing DNA synthesis  PHYS.ORG · 3 weeks
The final stage of DNA replication—"termination"—occurs when two DNA copy machines advance upon each other and unwind the final stretch of DNA. This process occurs about 60,000 times per human cell cycle and is crucial to prevent mutations. more
Advanced cancer drug shrinks and intercalates DNA  PHYS.ORG · 3 weeks
Because of the harmful side-effects of chemotherapy, and the increasing resistance to drugs found in many cancer cells, it is critical for researchers to continually search for new ways to update current cancer treatments.... more
Researchers find 'protein-scaffolding' for repairing DNA damage  PHYS.ORG · 3 weeks
At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired... more
Biomarker for schizophrenia can be detected in human hair  SCIENCE DAILY · 3 weeks
Working with model mice, post-mortem human brains, and people with schizophrenia, researchers have discovered that a subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain.... more
Researchers discover how the body repairs damaged DNA  NEWS MEDICAL · 3 weeks
Researchers from the University of Copenhagen have made an extraordinary discovery in how the body repairs damaged DNA, which can lead to better understanding and management of diseases such as cancer. more
NYU Langone Health launches new molecular assay to identify patients with brain tumors  NEWS MEDICAL · 3 weeks
NYU Langone Health and its Perlmutter Cancer Center have launched clinical whole genome DNA methylation profiling for patients with brain tumors. more
Genetically definable subgroups of cancers sensitive to treatment  NEWS MEDICAL · 3 weeks
Precision oncology aims to use genetic features of a patient's tumor to tailor anti-cancer therapy. DNA mutations in a drug target have provided a number of therapeutic opportunities; however, there are many... more
120-year-old extinct lizard specimen revealed by mitochondrial DNA  PHYS.ORG · 3 weeks
Together with a Ukrainian colleague, Senckenberg researchers examined the 120-year-old specimen of a "Crimean lizard." Until now, these animals had been considered a species of green lizard restricted to the Crimean Peninsula.... more
Self-organization of parS centromeres by the ParB CTP hydrolase  Science Magazine · 3 weeks
ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an... more
Researchers make neural networks successfully detect DNA damage caused by UV radiation  PHYS.ORG · 3 weeks
Researchers at Tomsk Polytechnic University jointly with the University of Chemistry and Technology (Prague) conducted a series of experiments which proved that artificial neural... more
Researchers discover conjugative plasmid that augments virulence in superbug  NEWS MEDICAL · 3 weeks
A recent research led by a scientist at City University of Hong Kong has discovered an easily transmitted DNA piece that can make a new type of hyper-resistant and deadly... more
Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer  NEWS MEDICAL · 3 weeks
A research team from the School of Chinese Medicine at Hong Kong Baptist University has successfully developed a novel aptamer, i.e. a single-stranded piece... more
Consuming alcohol leads to epigenetic changes in brain memory centers  SCIENCE DAILY · 3 weeks
New research revealed a surprising pathway that shows alcohol byproducts travel to the brain to promote addiction memory. They show how acetate travels to the brain's learning system... more
Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation  Science Magazine · 3 weeks
The characteristics of DNA methylation changes that occur during neurogenesis in vivo remain unknown. We used whole-genome bisulfite sequencing to quantitate DNA cytosine modifications in differentiating... more
New portable DNA sequencer quickly and accurately diagnoses wheat viruses  PHYS.ORG · 3 weeks
Blasts cause significant loses in wheat crops. Recently Bangladesh was devastated by an invasion of South American races of wheat blast fungus, which occurred for the first time... more
New portable DNA sequencer quickly and accurately diagnoses wheat viruses  SCIENCE DAILY · 3 weeks
A group of scientists have developed a new technology that makes it possible to rapidly identify viruses in wheat fields with a significantly higher accuracy. They collected four... more
SEPATH: New template to detect oncogenic viruses and bacteria in human DNA  NEWS MEDICAL · 3 weeks
A new study from the University of East Anglia describes a novel approach to detecting bacteria and viruses that may possibly be causing cancer.... more
Deaf couple may edit embryo’s DNA to correct hearing mutation  Science Magazine · 4 weeks
Russian parents weigh the risks and benefits of a scientist’s controversial proposal more
The secret of classic Belgian beers? Medieval super yeasts!  SCIENCE DAILY · 4 weeks
An international team of scientists has discovered that some of the most renowned classic Belgian beers, including Gueuze and Trappist ales, are fermented with a rare and unusual form of... more
GenBank can be trusted, study shows  SCIENCE DAILY · 4 weeks
Scientists working to identify coral reef organisms analyzed more than 4.7 million animal DNA sequences from GenBank, the most commonly used tool used to identify environmental DNA, and discovered that animal identification errors are surprisingly rare... more
Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection  NEWS MEDICAL · 4 weeks
A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment... more
Comparisons of 4.7 million mtDNA sequences show GenBank is reliable for animal IDs  PHYS.ORG · 4 weeks
Did a murderer walk through the room? Did a shark just swim by? Is this a poisonous mushroom? Which reef species are... more
Scientists Create New, More Powerful Technique To Edit Genes  NPR · 4 weeks
A new technique, dubbed 'prime editing,' appears to make it even easier to make very precise changes in DNA. It's designed to overcome the limits of the CRISPR gene editing... more
DNA-reeling bacteria yield new insight on how superbugs acquire drug-resistance  SCIENCE DAILY · 4 weeks
A study has revealed a protein's role in helping bacteria 'reel in' DNA from their environment to acquire new traits, such as antibiotic resistance. more
US takes step to require DNA samples from asylum-seekers  PHYS.ORG · 4 weeks
The Trump administration is planning to collect DNA samples from asylum-seekers and other migrants detained by immigration officials and will add the information to a massive FBI database used by... more
DNA-reeling bacteria yield new insight on how superbugs acquire drug-resistance  PHYS.ORG · 4 weeks
A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment—like a fisherman pulling up... more
The secret of classic Belgian beers? Medieval super-yeasts  PHYS.ORG · 4 weeks
An international team of scientists led by Prof. Kevin Verstrepen (VIB-KU-Leuven) and Prof. Steven Maere (VIB-UGent) has discovered that some of the most renowned classic Belgian beers, including Gueuze and Trappist ales,... more
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