Diseases
Study unveils new layers of mystery about visual memory, amblyopia  NEWS MEDICAL · 11 hours
In decades of studying how neural circuits in the brain's visual cortex adapt to experience, MIT Professor Mark Bear's lab has followed the science wherever it has led,... more
Using new high-resolution imaging to track titin in real time  NEWS MEDICAL · 11 hours
Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could... more
Salmonella causes nearly one in three foodborne outbreaks in the EU  NEWS MEDICAL · 12 hours
Nearly one in three foodborne outbreaks in the EU in 2018 were caused by Salmonella. This is one of the main findings of the annual report... more
New study improves understanding of widespread diseases  NEWS MEDICAL · 12 hours
When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process. more
NIH provides up to $102.5 million in renewed funding for Antibacterial Resistance Leadership Group  NEWS MEDICAL · 13 hours
As antibiotic-resistant bacteria become more urgent threats worldwide, the National Institute of Allergy and Infectious Diseases, part of the National... more
Researchers make significant advances in developing novel Zika virus vaccine  NEWS MEDICAL · 14 hours
Researchers from the University of Adelaide have made significant advances in developing a novel vaccine against Zika virus, which could potentially lead to global elimination of the disease. more
Holiday Parties Make You Squirm? Here's How To Conquer Social Anxiety  NPR · 22 hours
People with social anxiety disorder fear their "fatal flaws" will be exposed by a wayward comment or other social misstep. If holiday parties send you spiraling,... more
In surprise decision, US approves muscular dystrophy drug  ABC NEWS · 1 day
The U.S. Food and Drug Administration has approved a second drug to treat muscular dystrophy, the debilitating disease that causes loss of movement and early death more
Perinatal exposure of rats to flame retardants changes the liver epigenome  NEWS MEDICAL · 1 day
Studies have shown that perinatal exposure of rats and mice to common flame retardants found in household items permanently reprograms liver metabolism, often leading later in... more
IU researchers discover how to predict recurrence of triple negative breast cancer  NEWS MEDICAL · 1 day
Indiana University School of Medicine researchers have discovered how to predict whether triple negative breast cancer will recur, and which women are likely to... more
The wild relatives of major vegetables, needed for climate resilience, are in danger  PHYS.ORG · 2 days
Growing up in the wild makes plants tough. Wild plants evolve to survive the whims of nature and thrive in difficult conditions,... more
Flexible submental sensor patch with remote monitoring controls for management of oropharyngeal swallowing disorders  Science Magazine · 2 days
Successful rehabilitation of oropharyngeal swallowing disorders (i.e., dysphagia) requires frequent performance of head/neck exercises that primarily rely on expensive biofeedback... more
Miniaturized, light-adaptive, wireless dosimeters autonomously monitor exposure to electromagnetic radiation  Science Magazine · 2 days
Exposure to electromagnetic radiation (EMR) from the sun and from artificial lighting systems represents a modifiable risk factor for a broad range of health conditions including skin cancer,... more
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease  SCIENCE DAILY · 2 days
A new study showed that environmentally relevant exposure to polybrominated diphenyl ether (PBDE), a brominated flame retardant, through the umbilical cord and breast milk permanently changed liver metabolism... more
New study enhances knowledge about widespread diseases  SCIENCE DAILY · 2 days
When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process. more
Breakthrough in Zika virus vaccine  SCIENCE DAILY · 2 days
Researchers have made significant advances in developing a novel vaccine against Zika virus, which could potentially lead to global elimination of the disease. more
Researchers find many psychiatric disorders share the same gene variants  NEWS MEDICAL · 2 days
An international team of researchers has found that many psychiatric disorders share a common and specific set of gene variants. more
Human genetics evidence predictive of drug development success, study shows  NEWS MEDICAL · 2 days
A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can... more
Deadly 'superbugs' destroyed by molecular drills  nanowerk · 2 days
Motorized molecules activated by light target and drill through highly antibiotic resistant bacteria and kill them within minutes. The molecules can open bacteria to attack by drugs they previously resisted. The strategy could be applied to... more
Incidence of NTM lung disease appears to be increasing, especially among women and the elderly  NEWS MEDICAL · 2 days
The number of people newly infected each year and the number of people living with nontuberculous mycobacterial lung... more
Medical News Today: Could epigenome editing prevent developmental disorders?  MNT · 2 days
Using mice, scientists show how epigenome editing has promise as a way to fix disordered brain development that arises from a WAGR syndrome gene mutation. more
Medications prescribed to children with chronic kidney disease may harm their kidneys  NEWS MEDICAL · 2 days
An analysis of records from primary care practices in the United Kingdom found that many children with kidney disease are prescribed medications that may... more
New technique may lead to earlier and easier detection of mouth and throat cancer  NEWS MEDICAL · 2 days
Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become... more
People living with HIV are willing to risk near-certain death in clinical trial  NEWS MEDICAL · 2 days
Nearly one-quarter of people living with HIV were willing to risk near-certain death in a clinical trial, if volunteering for the trial... more
Precision epigenome editing can repair genetic syndrome of intellectual disability  NEWS MEDICAL · 2 days
Using a targeted gene epigenome editing approach in the developing mouse brain, Johns Hopkins Medicine researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome,... more
10-year results from clinical trial of extended letrozole therapy for women with HR+ breast cancer  NEWS MEDICAL · 2 days
In the updated results from NRG Oncology/NSABP B-42 trial through 10 years of observation, extending letrozole therapy for... more
Could epigenome editing prevent developmental disorders?  MNT · 2 days
Using mice, scientists show how epigenome editing has promise as a way to fix disordered brain development that arises from a WAGR syndrome gene mutation. more
Gulf war illness – one or two diseases?  NEWS MEDICAL · 2 days
A study of veterans who have Gulf war syndrome shows that moderate exercise can bring about a spectrum of brain imaging abnormalities, which fall into one of two groups. This could mean... more
Oncology social workers offer advice on managing holidays with a life-threatening illness  NEWS MEDICAL · 2 days
Stringing the lights, storming the malls and all those parties! Imagine facing these holiday demands while you're tired, sick, sad and worried: for people... more
Research suggests contributory role of 'Asian glow' mutation and alcohol to Alzheimer’s  NEWS MEDICAL · 2 days
A new study from Stanford, published on December 12 in the journal Acta Neuropathologica Communications, suggests that an important enzyme that helps break down... more
Scientists develop an approach to vaccinate against gut inflammation  NEWS MEDICAL · 3 days
Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied... more
Caribou migration linked to climate cycles and insect pests  PHYS.ORG · 3 days
Caribou, the North American cousin of reindeer, migrate farther than any terrestrial animal. They can cover thousands of miles as they move between winter feeding grounds and summer calving grounds.... more
Study offers new clues on identifying potential PTSD candidates among trauma sufferers  NEWS MEDICAL · 3 days
Most people who experience severe trauma recover their health. But 23 percent develop PTSD, a difficult-to-treat illness that combines intrusive thoughts about the trauma,... more
Wayne State's College of Engineering receives $1.7 million to develop novel insulin delivery system  NEWS MEDICAL · 3 days
Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin -- a hormone that regulates... more
Unique Missouri program shows access to dermatologists benefits doctors, patients  NEWS MEDICAL · 3 days
Fewer than 10% of dermatologists practice in rural areas, according to the Journal of the American Academy of Dermatology. That means primary care physicians (PCPs) are often relied... more
Insight into the neglected tropical disease sleeping sickness  SCIENCE DAILY · 3 days
Researchers have shed light on how the parasite which causes sleeping sickness multiples inside its host. Human African Trypanosomiasis or sleeping sickness, only occurs in Sub-Saharan Africa where an estimated 60 million... more
Researchers aim to improve oral delivery of insulin for diabetes patients  NEWS MEDICAL · 3 days
Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin -- a hormone that regulates blood sugar-- or the body cannot... more
Your genes aren't the only factor dictating Alzheimer's risk  SCIENCE DAILY · 3 days
In the first study published about Alzheimer's disease among identical triplets, researchers found that despite sharing the same DNA, two of the triplets developed Alzheimer's while one did not. more
Deadly 'superbugs' destroyed by molecular drills  SCIENCE DAILY · 3 days
Motorized molecules activated by light target and drill through highly antibiotic resistant bacteria and kill them within minutes. The molecules can open bacteria to attack by drugs they previously resisted. The strategy could be applied to... more
A window into the hidden world of colons  SCIENCE DAILY · 3 days
Biomedical engineers have developed a system for real-time observations at the cellular level in the colon of a living mouse. It employs a magnetic system to stabilize the colon during imaging while... more
Geneticists identify small molecules that are potential indicators for disease  SCIENCE DAILY · 3 days
Researchers identified hundreds of metabolites that might serve as intermediates to translate variation in the genome to variation in complex traits. Findings could someday facilitate early or more... more
Dendritic cells could lead to better treatments for persistent infections, cancer  NEWS MEDICAL · 3 days
Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose... more
Safer viruses for vaccine research and diagnosis  SCIENCE DAILY · 3 days
A new technology to produce safer 'hybrid' viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed. more
A digital approach to proteins and cancer  SCIENCE DAILY · 3 days
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
Microglia monitor and protect neuronal function via specialized somatic purinergic junctions  Science Magazine · 3 days
Microglia are the main immune cells in the brain with roles in brain homeostasis and neurological diseases. Mechanisms underlying microglia-neuron communication remain elusive. Here, we identified... more
Medical News Today: Transport breakdown in brain cells may lead to Alzheimer's, Parkinson's  MNT · 3 days
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative... more
Team finds bovine kobuvirus in US  PHYS.ORG · 3 days
A virus that afflicts cattle that was first discovered in Japan in 2003 has made its way to the U.S., researchers report in the journal Emerging Infectious Diseases. more
Researchers making major inroads into finding the cause of different diseases  NEWS MEDICAL · 3 days
Australian researchers are making major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected... more
New insights into the most perplexing medical mysteries associated with schizophrenia  NEWS MEDICAL · 3 days
Four unsolved mysteries around schizophrenia have long plagued the medical community, but a new hypothesis identifying a common link between them and an almost forgotten epidemic... more
Anastrozole can be preventive drug-of-choice for women with high breast cancer risk  NEWS MEDICAL · 3 days
The Queen Mary University of London professor leading an international breast cancer study says anastrozole - rather than tamoxifen - should be the preventive drug-of-choice for... more
New insights to major disease pathways  PHYS.ORG · 3 days
Flinders researchers have made major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected by oxidative stress in the human body. more
Researchers discover cause of a previously unknown autoinflammatory disorder, CRIA syndrome  NEWS MEDICAL · 3 days
Researchers have identified the genetic cause of an autoinflammatory disease, CRIA, a previously unknown disorder. more
Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension  NEWS MEDICAL · 3 days
High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs. more
Researchers discover cause of a previously unknown autoinflammatory disorder  NEWS MEDICAL · 3 days
Researchers have identified the genetic cause of an autoinflammatory disease, CRIA, a previously unknown disorder. more
A recombinant platform for flavivirus vaccines and diagnostics using chimeras  NEWS MEDICAL · 3 days
A new technology to produce safer ‘hybrid’ viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland. more
New method reveals how microbial communities function in our bodies  NEWS MEDICAL · 3 days
In the last decade, scientists have made tremendous progress in understanding that groups of bacteria and viruses that naturally coexist throughout the human body play an important role... more
Flipping the script on novel cancer therapy leads to insights into lupus  SCIENCE DAILY · 3 days
In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms... more
A way to 'fingerprint' human cells  PHYS.ORG · 3 days
Researchers say a new method to analyse data from individual human cells could be a step-change for diagnosing some of the most devastating diseases, including cancer and autoimmune disease. more
Transport breakdown in brain cells may lead to Alzheimer's, Parkinson's  MNT · 3 days
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases. more
New software to help researchers study specific information about proteins  NEWS MEDICAL · 3 days
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
University Of Iowa wins $18 million grant to continue study on Huntington's disease  NEWS MEDICAL · 3 days
Peg Nopoulos, MD, chair of psychiatry and professor of psychiatry, neurology, and pediatrics in the University of Iowa Carver College of Medicine,... more
UCLA scientists discover reason for higher rates of autoimmune disease in women than men  NEWS MEDICAL · 3 days
UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men. more
New drug combo promises help for triple negative breast cancer patients  NEWS MEDICAL · 3 days
A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when... more
Epigenome editing could repair genetic brain disorder  NEWS MEDICAL · 3 days
A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of... more
Gut disease and gene analysis networks  NEWS MEDICAL · 3 days
Gut diseases are difficult to diagnose in many cases, and their underlying dysfunction is hard to understand in many cases. Now, a new study published in the journal Molecular Omics promises to uncover a better insight... more
Immune cells repair damaged gut in children with IBD  NEWS MEDICAL · 3 days
According to a new study published in the journal Gastroenterology, immune cells of a certain kind which regulate inflammatory processes and even help restore normal gut function after inflammation could... more
Experimental Alzheimer’s drugs show promise  NEWS MEDICAL · 4 days
Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their... more
Uncovering how endangered pangolins, or 'scaly anteaters,' digest food  SCIENCE DAILY · 4 days
The endangered Sunda pangolin, or 'scaly anteater,' is a widely trafficked mammal, prized in some cultures for its meat and scales. Little is known about these animals, and raising rescued... more
Non-drug therapies may reduce adverse outcomes in service members with chronic pain  NEWS MEDICAL · 4 days
A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the... more
Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's  NEWS MEDICAL · 4 days
The colour of our eyes or the straightness of our hair is linked to our DNA, but the development of Alzheimer's disease isn't exclusively... more
New human autoinflammatory disease  SCIENCE DAILY · 4 days
Scientists from Australia and the US have discovered and identified the genetic cause of a previously unknown human autoinflammatory disease. The researchers determined that the autoinflammatory disease, which they termed CRIA (cleavage-resistant RIPK1-induced autoinflammatory) syndrome, is caused by a mutation... more
Researchers test vaccine strategy for chronic inflammatory diseases  NEWS MEDICAL · 4 days
Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their... more
Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress  NEWS MEDICAL · 4 days
More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high... more
Scientists evaluate mouse models used for developing new treatments for Huntington's disease  NEWS MEDICAL · 4 days
Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal... more
Necrotizing enterocolitis is preceded by increased gut bacterial replication, Klebsiella, and fimbriae-encoding bacteria  Science Magazine · 4 days
Necrotizing enterocolitis (NEC) is a devastating intestinal disease that occurs primarily in premature infants. We performed genome-resolved metagenomic analysis of 1163 fecal... more
LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE  Science Magazine · 4 days
Long noncoding RNAs (lncRNAs) are important regulators of diverse biological processes; however, their function in macrophage activation is undefined. We... more
High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease  Science Magazine · 4 days
Respiratory complex I is a redox-driven proton pump, accounting for a large part of the electrochemical gradient that powers mitochondrial adenosine triphosphate synthesis. Complex I dysfunction... more
Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy  Science Magazine · 4 days
Facioscapulohumeral muscular dystrophy (FSHD) is linked to epigenetic derepression of the germline/embryonic transcription factor DUX4 in skeletal muscle. However, the... more
[Research Articles] Distinct neural mechanisms for the prosocial and rewarding properties of MDMA  Science Magazine · 4 days
The extensively abused recreational drug (±)3,4-methylenedioxymethamphetamine (MDMA) has shown promise as an adjunct to psychotherapy for treatment-resistant psychiatric disease. It is unknown,... more
[Editors' Choice] Mass-producing wearable sensors: No sweat  Science Magazine · 4 days
Laser engraving can mass-produce cost-efficient, wearable sensors that monitor vital signs and sweat, detecting biomarkers linked to chronic diseases. more
[Research Articles] PD-1H (VISTA)-mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus  Science Magazine · 4 days
Systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE) of the skin are autoimmune diseases characterized by inappropriate immune responses against self-proteins;... more
[Research Articles] Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy  Science Magazine · 4 days
Epidermal growth factor receptor (EGFR)–targeted anticancer therapy induces stigmatizing skin toxicities affecting patients’ quality of life and therapy... more
[Research Articles] Caveolin-1-derived peptide limits development of pulmonary fibrosis  Science Magazine · 4 days
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with a median 5-year survival of ~20%. Current U.S. Food and Drug Administration–approved pharmacotherapies slow progression of IPF, providing hope... more
Medical News Today: STDs: How do you get one?  MNT · 4 days
People can transmit and contract sexually transmitted diseases (STDs), or sexually transmitted infections, through several types of sexual contact. Learn more about STDs here. more
Medical News Today: What to know about non-Hodgkin lymphoma  MNT · 4 days
Non-Hodgkin lymphoma refers to a group of cancers that start in the white blood cells. This article looks at their types, symptoms, diagnosis, and treatment. more
Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease  NEWS MEDICAL · 4 days
The sweeping extent to which increasing 40Hz "gamma" rhythm power in the brain can affect the pathology and symptoms of Alzheimer's disease... more
Site search: A digital approach to proteins and cancer  PHYS.ORG · 4 days
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
Research suggests new strategies for developing psoriasis therapies  NEWS MEDICAL · 4 days
Psoriasis is a skin disorder that affects at least 100 million individuals worldwide. Its economic impact is more than $10 billion annually in the U.S. alone. more
New research may help guide future treatment for non-alcoholic fatty liver disease  NEWS MEDICAL · 4 days
Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron... more
The secret to a long life? For worms, a cellular recycling protein is key  SCIENCE DAILY · 4 days
Scientists have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic... more
A machine learning approach to identify functional human phosphosites  SCIENCE DAILY · 4 days
Scientists have created the largest phosphoproteome resource to date, which is set to help other researchers identify new functionally-relevant phosphosites. The research demonstrates an exciting use for machine learning methods... more
Altering intestinal microbiota, vaccinating against inflammatory diseases  SCIENCE DAILY · 4 days
Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array... more
Uncovering how endangered pangolins, or 'scaly anteaters,' digest food  PHYS.ORG · 4 days
The endangered Sunda pangolin, or "scaly anteater," is a widely trafficked mammal, prized in some cultures for its meat and scales. Little is known about these animals, and raising rescued... more
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