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Four genes associated with OCD identified
NEWS MEDICAL There are found genes that have been identified to be associated with obsessive compulsive disorder (OCD). These genes have been found to alter the circuitry of the brain in a manner that could lead to OCD.... 1 hour
TGen project to develop standard operating procedures for single-cell RNA sequencing
NEWS MEDICAL The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation,... 3 hours
Schizophrenia disrupts the brain's entire communication system, researchers say
SCIENCE DAILY Some 40 years since CT scans first revealed abnormalities in the brains of schizophrenia patients, international scientists say the disorder is a systemic disruption to the brain's entire communication system.... 5 hours
High blood pressure linked to common heart valve disorder
SCIENCE DAILY For the first time, a strong link has been established between high blood pressure and the most common heart valve disorder in high-income countries. 5 hours
New imaging system offers better way to monitor brain changes from Alzheimer's in mouse models
NEWS MEDICAL An estimated 5.5 million Americans live with Alzheimer's disease, a type of dementia that causes problems with memory,... 7 hours
On-and-off fasting helps fight obesity, study finds
SCIENCE DAILY Up to sixteen weeks of intermittent fasting without otherwise having to count calories helps fight obesity and other metabolic disorders. Such fasting already shows benefits after only six weeks, according to a new study. 10 hours
New imaging approach maps whole-brain changes from Alzheimer's disease in mice
SCIENCE DAILY A new imaging system that offers a better way to monitor the brain changes indicative of Alzheimer's in mouse models of the disease could help speed... 11 hours
Medical News Today: Schizophrenia affects whole-brain connectivity, major study finds
MNT The largest ever big data study of schizophrenia finds that the entire communication system in the brain's white matter is disrupted in the disease. 12 hours
Schizophrenia affects whole-brain connectivity, major study finds
MNT The largest ever big data study of schizophrenia finds that the entire communication system in the brain's white matter is disrupted in the disease. 12 hours
New imaging approach maps whole-brain changes from Alzheimer's disease in mice
PHYS.ORG An estimated 5.5 million Americans live with Alzheimer's disease, a type of dementia that causes problems with memory, thinking and behavior. Although treatments can slow the... 13 hours
Search Of DNA In Dogs, Mice And People Finds 4 Genes Linked To OCD
NPR Scientists looking for genetic factors behind obsessive compulsive disorder looked for clues in the DNA of humans and two animal... 14 hours
Portable 3-D scanner assesses patients with elephantiasis
SCIENCE DAILY An estimated 120 million people worldwide are infected with lymphatic filariasis, a parasitic, mosquito-borne disease that can cause major swelling and deformity of the legs, a condition known as elephantiasis. Scientists have shown that... 15 hours
Study sheds new light on why autism is more common in boys
NEWS MEDICAL Researchers aiming to understand why autism spectrum disorders (ASD) are more common in boys have discovered differences in a brain signaling pathway involved in... 17 hours
USC study reveals how schizophrenia has biological effect on the entire brain
NEWS MEDICAL Some 40 years since CT scans first revealed abnormalities in the brains of schizophrenia patients, international scientists say the disorder is a systemic disruption... 18 hours
Discovery may lead to new approach for treating MS
NEWS MEDICAL Around 2.5 million people are affected by the autoimmune disease Multiple Sclerosis (MS), the commonest central nervous system disease among young adults. 19 hours
ESnet's science DMZ design could help transfer, protect medical research data
PHYS.ORG Like other sciences, medical research is generating increasingly large datasets as doctors track health trends, the spread of diseases, genetic causes of illness and the like.... 22 hours
Plague outbreak in Madagascar kills 57 and rages on
NEWS MEDICAL The plague outbreak in Madagascar is killing scores of people and affecting hundreds. Last estimated on the 12th of October 2017, there are 57 reported deaths due to the disease... 1 day
Wake Forest Baptist scientists win grant to develop more effective treatments for brain cancer
NEWS MEDICAL Glioblastoma is the most aggressive cancer that originates in the brain. Current therapies can slow the disease, but more often... 1 day
Portable scanner can measure limb disfigurement easily in patients with elephantiasis
NEWS MEDICAL An estimated 120 million people worldwide are infected with lymphatic filariasis, a parasitic, mosquito-borne disease that can cause major swelling and deformity of the legs, a... 1 day
Findings reveal how seizures can have lasting detrimental effects on memory
NEWS MEDICAL Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling.... 1 day
Brain training shows promise for patients with bipolar disorder
SCIENCE DAILY Computerized brain training can result in improved cognitive skills in individuals with bipolar disorder, researchers have discovered for the first time. 1 day
IGeneX launches three new tests to aid diagnosis of Borreliosis
NEWS MEDICAL IGeneX Inc., a CLIA and New York-approved Reference Laboratory, specializing in testing for tick-borne diseases, is pleased to announce the launch of three new tests that are more inclusive and... 1 day
Gut fungi might be linked to obesity and inflammatory bowel disorders
SCIENCE-NEWS Fungi are overlooked contributors to health and disease. 1 day
Report sheds light on global market for infectious disease immunoassays
NEWS MEDICAL Kalorama Information says that infectious disease immunoassays beat the IVD market and the overall IVD market in terms of revenue growth. Immunoassays are tests that are based on... 1 day
Neutrons observe vitamin B6-dependent enzyme activity useful for drug development
SCIENCE DAILY Scientists have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria and... 2 days
Gestational diabetes and cardiovascular disease risk
SCIENCE DAILY A history of gestational diabetes was associated with a modest higher long-term risk of cardiovascular disease in women in a new study, although the absolute rate of cardiovascular disease was low in the study's younger group... 2 days
Neutrons observe vitamin B6-dependent enzyme activity useful for drug development
PHYS.ORG Scientists at the Department of Energy's Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs... 2 days
New exercises help athletes manage dangerous breathing disorder
SCIENCE DAILY A novel set of breathing techniques help athletes overcome vocal cord dysfunction and improve performance during high-intensity exercise. Vocal cord dysfunction, now also referred to as exercise-induced laryngeal obstruction (EILO), has been... 2 days
Scientists demonstrate path to linking the genome to healthy tissues, disease
SCIENCE DAILY A study has reached a major milestone in establishing a baseline understanding of gene expression across healthy human tissues, and linking genes to disease. 2 days
Endogenous infection marker can help guide antibiotic use
NEWS MEDICAL The endogenous infection marker procalcitonin can help to guide the use of antibiotics when treating infections. The course of antibiotic therapy is shortened, and its side effects and mortality rate also decrease,... 2 days
Medical News Today: What is psychomotor agitation?
MNT Psychomotor agitation can cause a person to make movements without meaning to. It is a symptom of several conditions, including bipolar disorder. 2 days
Researchers to investigate cellular changes leading to development of glioblastoma
NEWS MEDICAL Glioblastoma is the most common of malign brain tumors in adults, and it currently has no cure. Now a research team led by Dr Claudia Barros, from the... 2 days
Increasing our understanding of the impact of compounds produced by certain fish parasites
PHYS.ORG European aquaculture production provides direct employment to 80 000 people and has an estimated EUR 3 billion annual turnover. But parasites can... 2 days
Unexpected finding in the cell's power plant
PHYS.ORG Researchers at Karolinska Institutet have discovered that the protein complex RNase P in the cell's mitochondria behaves differently than previously thought. The findings, published in Nucleic Acids Research, give important new clues on how... 2 days
Report: Global burden of neurological disorders in today’s world
NEWS MEDICAL Globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy etc) has increased substantially over the past 25 years. 3 days
MS risk in children spotted with MRI brain scans
SCIENCE DAILY By the time multiple sclerosis (MS) is diagnosed in children, it may be difficult to prevent the disabilities and relapses that come with the disease. In a new study, researchers... 4 days
A dietary supplement dampens the brain hyperexcitability seen in seizures or epilepsy
SCIENCE DAILY Researchers have found that inducing a biochemical alteration in brain proteins via the dietary supplement glucosamine was able to rapidly dampen that pathological hyperexcitability... 4 days
Dietary supplement could be promising therapeutic target for seizure disorders
NEWS MEDICAL Seizure disorders -- including epilepsy -- are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability. 4 days
New study maps human genome to healthy tissue functions and disease processes
NEWS MEDICAL Our genomes help to determine who we are - the countless variations between individuals that encode the complexity of tissues and functions throughout the... 4 days
MRI brain scans can reveal MS risk in children before clinical symptoms appear
NEWS MEDICAL By the time multiple sclerosis (MS) is diagnosed in children, it may be difficult to prevent the disabilities and relapses that come... 4 days
Integrating networks and comparative genomics reveals retroelement proliferation dynamics in hominid genomes
Science Magazine Retroelements (REs) are mobile DNA sequences that multiply and spread throughout genomes by a copy-and-paste mechanism. These parasitic elements are active in diverse genomes,... 4 days
Worms reveal secrets of aging
SCIENCE DAILY Investigators have identified a new molecular pathway that controls lifespan and healthspan in worms and mammals. Researchers have shown that worms with excess levels of certain proteins lived longer and healthier than normal worms. In addition, mice with... 4 days
Cell biology: Proteins may prevent dysfunction, disease by relaxing, study shows
SCIENCE DAILY A team of researchers used simulations and X-rays to conclude that disordered proteins remain unfolded and expanded as they float loose in the cytoplasm of a... 4 days
First atomic structure from cryo-EM facility
SCIENCE DAILY Researchers have outlined a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. 5 days
Uncovering origins of developmental brain disorders could eventually help treat seizures
SCIENCE DAILY New research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some children with autism. 5 days
Scientists help show links between genes, body tissues
SCIENCE DAILY A research team is assessing how a person's genetic profile affects his body. The results could help show how individual genetic differences contribute to disease and guide treatments for heritable disorders such... 5 days
3-D atomic structure of TRPML1 ion channel published
PHYS.ORG UT Southwestern Medical Center researchers today published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. The work marks the... 5 days
WATCH: Beyond the scale: What to eat to lower your risk for 3 health issues
ABC NEWS Dr. Jennifer Ashton and nutritionist Maya Feller discuss some foods you should add to every meal to reduce... 5 days
New mechanism detected in Alzheimer's disease
SCIENCE DAILY Researchers have discovered a cellular mechanism that may contribute to the breakdown of communication between neurons in Alzheimer's disease. In the brain tissue of Alzheimer's patients, the RNAs that encode synaptic proteins are degraded more rapidly... 5 days
Proteins may prevent dysfunction, disease by relaxing, study shows
SCIENCE DAILY A team of researchers used simulations and X-rays to conclude that disordered proteins remain unfolded and expanded as they float loose in the cytoplasm of a cell. The answer affects... 5 days
New x-ray analysis methodology reveals structure of disordered protein
NEWS MEDICAL Scientists at The University of Notre Dame have shown that disordered proteins have a structure very close to what would be expected for a truly random structure using a novel... 5 days
McGill researchers discover new cellular mechanism in Alzheimer's disease
NEWS MEDICAL McGill University researchers have discovered a cellular mechanism that may contribute to the breakdown of communication between neurons in Alzheimer's disease. 5 days
Medical News Today: Childhood respiratory infections linked with celiac disease
MNT New research concludes that respiratory infections in at-risk children may significantly increase the likelihood of developing celiac disease. 5 days
Medical News Today: What is diabetic nephropathy?
MNT Diabetic nephropathy is kidney disease that occurs in people with diabetes. It can cause serious complications, including kidney failure. Learn more. 5 days
Childhood respiratory infections linked with celiac disease
MNT New research concludes that respiratory infections in at-risk children may significantly increase the likelihood of developing celiac disease. 5 days
New protein study broadens knowledge of molecular basis for disease
PHYS.ORG Determining how proteins function on a molecular level is crucial to understanding the underlying basis for disease. Now scientists at the University of Notre Dame are one step... 5 days
Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work
NEWS MEDICAL Determining how proteins function on a molecular level is crucial to understanding the underlying basis for disease. Now scientists at the University... 5 days
New protein study broadens knowledge of molecular basis for disease
SCIENCE DAILY Scientists are one step closer to unraveling the mystery of how intrinsically disordered proteins work, according to new research. 5 days
Mechanism for precise targeting of the immune response uncovered
SCIENCE DAILY The immune system checks the health of cells of the body by examining a kind of molecular passport. Sometimes cells present the wrong passport, which can lead to autoimmune diseases,... 5 days
Climate change may accelerate infectious disease outbreaks, say researchers
SCIENCE DAILY Aside from inflicting devastating natural disasters on often vulnerable communities, climate change can also spur outbreaks of infectious diseases like Zika , malaria and dengue fever, according to a new... 5 days
MIT researchers develop new technique to screen for genes that protect against diseases
NEWS MEDICAL Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect... 5 days
Strange undertakings: Ant queens bury dead to prevent disease
PHYS.ORG Ant queens may bury other queens - a task normally performed by workers - to avoid infection when co-founding a new colony, according to a study published in the open... 5 days
Cellular reprograming implicated in model of Alzheimer's disease
MIT Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer's disease. 5 days
Research findings could pave way to new therapies for treating seizures and autism
NEWS MEDICAL Recent research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some... 5 days
Mitochondrial DNA could predict risk for sudden cardiac death, heart disease
SCIENCE DAILY The level, or 'copy number,' of mitochondrial DNA -- genetic information stored not in a cell's nucleus but in the body's energy-creating mitochondria -- is a... 5 days
FDA Panel Endorses Gene Therapy For A Form Of Childhood Blindness
NPR Food and Drug Administration advisers unanimously recommended that the agency approve the first gene therapy for an inherited disease — a rare defect that causes blindness... 5 days
3-D packaging of DNA regulates cell identity
PHYS.ORG VIDEO The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down... 5 days
Chemistry provides a new supply of a promising cancer and HIV treatment
SCIENCE DAILY Supplies of a promising drug for cancer, HIV and possibly other diseases is dwindling, and scientists have struggled to extract more from the marine... 5 days
Unraveling the genetics of disc disease in dogs
SCIENCE DAILY Since the early 1900s, veterinarians have observed intervertebral disc disease -- a common cause of back pain, rear limb paralysis and inability to walk -- more frequently in dogs with short legs... 5 days
Criminal offenders with genetic mental disorders judged more negatively
SCIENCE DAILY Popular literature and crime dramas imply that defense attorneys who portray their clients as victims may have better outcomes. The belief is that jurors assign less blame to defendants they... 5 days
Chemistry provides a new supply of a promising cancer and HIV treatment
PHYS.ORG A drug isolated from a marine pest holds promise for treating some of the world's nastiest diseases, and researchers would love to find out... 5 days
Cause of cancer form in the liver identified
SCIENCE DAILY Researchers have identified the two genes whose mutation cause a serious cancer form found in the liver. The result sets concrete goals for future treatment of the otherwise incurable disease. 5 days
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
Science Magazine A substantial fraction of the proteome is intrinsically disordered, and even well-folded proteins adopt non-native geometries during synthesis, folding, transport, and turnover. Characterization of... 5 days
An expanded view of disordered proteins
Science Magazine 5 days
Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV
Science Magazine Bryostatin 1 is an exceedingly scarce marine-derived natural product that is in clinical development directed at HIV/AIDS eradication, cancer immunotherapy, and the treatment of... 5 days
New technique scours the genome for genes that combat disease
SCIENCE DAILY Using a modified version of the CRISPR genome editing system, researchers have developed a new way to screen for genes that protect against specific diseases. They used this... 6 days
How rabies can induce frenzied behavior
SCIENCE DAILY Scientists may finally understand how the rabies virus can drastically change its host's behavior to help spread the disease, which kills about 59,000 people annually. A new study shows how a small piece of the rabies... 6 days
Autism prevalence and socioeconomic status: What's the connection?
SCIENCE DAILY Children living in neighborhoods where incomes are low and fewer adults have bachelor's degrees are less likely to be diagnosed with autism spectrum disorder compared to kids from more affluent neighborhoods. 6 days
A method to screen unknown molecules of coral reefs for their therapeutic potential
PHYS.ORG Coral reefs harbor an incredible diversity of life, both sea creatures we can see and microbial life that we cannot. These organisms... 6 days
Criminal offenders with genetic mental disorders assigned more blame, harsher punishment
NEWS MEDICAL Popular literature, crime dramas and recent trials dominating the media imply that defense attorneys who portray their clients as victims may have better outcomes. 6 days
WHO announces establishment of new high-level commission to tackle NCDs
NEWS MEDICAL Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization, announced today the establishment of a new High-level global Commission on Noncommunicable Diseases (NCDs). 6 days
Crown Bioscience announces availability of new translational models for obesity and diabetes in Europe
NEWS MEDICAL Crown Bioscience, a wholly-owned subsidiary of Crown Bioscience International and a global drug discovery and development services company providing translational... 6 days
New technique scours the genome for genes that combat disease
PHYS.ORG Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases. 6 days
Dementia patient at center of spoon-feeding controversy dies
NEWS MEDICAL An Oregon woman with Alzheimer's disease, whose husband claimed she was kept alive with spoon-feeding against her written wishes, has died. 6 days
New technique scours the genome for genes that combat disease
MIT Biological engineers identify genes that protect against protein linked to Parkinson’s disease. 6 days
Survey: Migraine affects work productivity, relationships, and employment of sufferers
NEWS MEDICAL A significant percentage of migraine sufferers as well as those without the disease are concerned that migraine affects work productivity, quality of life, family/relationships and employment, according to... 6 days
WATCH: Puerto Ricans face growing threat from disease
ABC NEWS 3.4 million U.S. citizens on the island are now facing a public health threat. 6 days
Confusion about long-term treatment of osteoporosis clarified
SCIENCE DAILY Osteoporosis is a common disorder among postmenopausal women which results in an increased risk of fractures. While several therapies improve bone strength and reduce the risk of spine and hip fracture, there is no... 6 days
Traumatic events take toll on the heart
SCIENCE DAILY Today it seems about everything has been shown to lead to heart disease. Of course smoking is bad for you, as is high blood pressure. There's even mounting evidence that psychosocial factors can cause... 6 days
Hormone therapy may benefit migraine sufferers without increased risk of heart disease
SCIENCE DAILY Migraine headaches are common among women, but due to various health risks can be challenging to treat in the elderly. While hormone therapy is... 6 days
Stepped care beneficial after hurricanes
SCIENCE DAILY Stepped care is more effective than usual care in reducing the prevalence of posttraumatic stress disorder in the aftermath of hurricanes, according to a new study. 6 days
Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis
Science Magazine Combinations of three or more drugs are used to treat many diseases, including tuberculosis. Thus, it is important to understand how synergistic or antagonistic drug interactions... 6 days
[Research Articles] Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1
Science Magazine Targeted genome editing in hematopoietic stem/progenitor cells (HSPCs) is an attractive strategy... 6 days
[Research Articles] An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target
Science Magazine Interleukin (IL)–36α, IL-36β, and IL-36 are... 6 days
Unraveling the genetics of disc disease in dogs
PHYS.ORG Since the early 1900s, veterinarians have observed intervertebral disc disease—a common cause of back pain, rear limb paralysis and inability to walk—more frequently in dogs with short legs (dachshund, French bulldog, and... 6 days
Deciphering biological meaning from an atlas of gene expression across 42 tissue types
SCIENCE DAILY The human genome encodes instructions for which genes are expressed in what cell type, along with other molecules that control how much... 6 days
New Therapy Halts Rare Brain Disease Depicted in 'Lorenzo's Oil'
LIVE SCIENCE Doctors have successfully suppressed a rare brain disease that typically strikes young boys, by using a novel type of therapy that alters a patient's genes. 7 days
Medical News Today: Menopause may trigger Alzheimer's disease
MNT A new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer's disease. 7 days
Criminal offenders with genetic mental disorders judged more negatively
PHYS.ORG Popular literature, crime dramas and recent trials dominating the media imply that defense attorneys who portray their clients as victims may have better outcomes. The belief is that jurors assign... 7 days
Puerto Rico investigates post-hurricane disease outbreak
PHYS.ORG Four deaths in Hurricane Maria's aftermath are being investigated as possible cases of a disease spread by animals' urine, Puerto Rico's governor said Wednesday amid concerns about islanders' exposure to contaminated water. 7 days
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3-D packaging of DNA regulates cell identity
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New mobile app diagnoses crop diseases in the field and alerts rural farmers
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