Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could... more
When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process. more
Although there is no consensus on which diet is the most sustainable, there are many steps a person can take to reduce their environmental impact. Learn more here. more
The U.S. Food and Drug Administration has approved a second drug to treat muscular dystrophy, the debilitating disease that causes loss of movement and early death more
A United Nations report says nearly a half-billion people in the Asia-Pacific are still malnourished and to achieve a goal of zero hunger by 2030 requires that millions escape food... more
Quantum-mechanical van der Waals dispersion interactions play an essential role in intraprotein and protein-water interactions—the two main factors affecting the structure and... more
When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process. more
A scientific collaboration has resulted in the construction of a synthetic DNA nanopore capable of selectively translocating protein-size macromolecules across lipid bilayers. more
A new study of females aged 50 and over suggests that those who include more refined carbohydrates in their diet have an increased risk of insomnia. more
Control of the polarization of light is a key feature for displays, optical data storage, optical quantum information, and chirality sensing. In particular, the direct emission of circularly polarized (CP) light has... more
In 2015, the first commercial nanopore DNA sequencing device was introduced by Oxford Nanopore Technologies. Based on a synthetically engineered transmembrane protein, nanopore sequencing allows long DNA strands to be channelled through the central... more
Pathogens can use a range of toxins to damage their host organism. Bacteria, such as those responsible for causing the deadly Plague, use a special injection mechanism to deliver their poisonous contents into the host cell. Stefan Raunser, Director at... more
Researchers at the University of Exeter, UK, followed a population of wild banded mongooses (Mungos mungo) in western Uganda for 15 years, using ultrasound imaging to track which females became pregnant and which carried to full term. They... more
Spider webs are one of nature's most fascinating manifestations. Many spiders extrude proteinaceous silk to weave sticky webs that ensnare unsuspecting prey who venture into their threads. Despite their elasticity, these webs... more
What do marine mammals eat? It's a simple question with profound implications for marine-mammal conservation and fisheries research. But it can a... more
Europe's Great Famine of 1315–1317 is considered one of the worst population collapses in the continent's history. Historical records tell of unrelenting rain accompanied by mass crop failure,... more
"Everything is determined by forces over which we have no control... Human beings, vegetables, or cosmic dust, we all dance to a mysterious tune, intoned in the distance... more
DigiM Solution LLC, a provider of microstructure characterization and optimization solutions and software, has received a contract from the Office of Generic Drugs of the U.S. Food and Drug Administration. more
Pure and highly concentrated caffeinated food products will be banned from today as the Australian Government continues to deliver on its earlier commitment to protect consumers. more
Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor,... more
A new, objective way of measuring flavanol intake has been developed, which could help nutritional experts assess the link between these compounds and their health benefits at scale. more
In a mouse study, researchers have tested the potential of a ketone ester-rich diet in slowing down Alzheimer's, and have found this approach promising. more
Weight loss mandates healthy eating and control of impulses when it comes to eating fat rich and processed foods. The actual story is quite different, as most persons... more
Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied... more
If you're prone to depression, this holiday season you might want to say "bah humbug" to offers of sugar plum pudding, caramel corn and chocolate babka. more
Caribou, the North American cousin of reindeer, migrate farther than any terrestrial animal. They can cover thousands of miles as they move between winter feeding grounds and summer calving grounds.... more
The Endocrine Society and Avalere Health introduced the first-ever quality measures to help healthcare providers assess how well they identify and care for older... more
High-fat diets and obesity have been shown to increase the risk of breast cancer and worsen outcomes and prognosis of breast cancer patients. A team of... more
The transformation and degradation of natural landscapes due to human activities has been intensifying for several decades. This is especially true for... more
Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the... more
Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin -- a hormone that regulates blood sugar-- or the body cannot... more
Researchers have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum... more
Oligosaccharyltransferase (OST) catalyzes the transfer of a high-mannose glycan onto secretory proteins in the endoplasmic reticulum. Mammals express two distinct OST complexes that act in a cotranslational (OST-A)... more
The p27 protein is a canonical negative regulator of cell proliferation and acts primarily by inhibiting cyclin-dependent kinases (CDKs). Under some circumstances, p27 is associated with active CDK4,... more
Biomedical engineers have developed a system for real-time observations at the cellular level in the colon of a living mouse. It employs a magnetic system to stabilize the colon during imaging while... more
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
The number of malnourished people is increasing worldwide. More than two billion people suffer from a lack of micronutrients. Infant mortality rates are unacceptably high. Against this background, there is a need for the global pooling... more
Peanut butter is high in protein and high in fat, but will it make you gain weight? Read this article to learn how peanut butter affects your weight. more
Folate and folic acid are forms of vitamin B-9. Folate occurs naturally in a range of foods, while folic acid is synthetic and present in fortified foods. Both... more
In a mouse study, researchers have tested the potential of a ketone ester-rich diet in slowing down Alzheimer's, and have found this approach promising. more
Spider webs are one of nature's most fascinating manifestations. Many spiders extrude proteinaceous silk to weave sticky webs that ensnare unsuspecting prey who venture into their threads. Despite their elasticity, these webs... more
Australian researchers are making major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected... more
Flinders researchers have made major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected by oxidative stress in the human body. more
Looking to gain a deeper understanding of cancer, a team led by researchers at Baylor College of Medicine conducted an extensive computational analysis of the similarities and differences... more
New research funded by the Frozen Food Foundation developed a modeling tool to assist the frozen food industry with understanding and managing listeriosis risks. The findings... more
In the last decade, scientists have made tremendous progress in understanding that groups of bacteria and viruses that naturally coexist throughout the human body play an important role... more
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases. more
An estimated 30% of adults experience insomnia, and a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons suggests that diet may be partly to blame. more
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
Participants who ate a diet high in red and processed meat, fried food, refined grains and high-fat dairy were three times more likely to develop late-stage age-related macular degeneration. more
The endangered Sunda pangolin, or 'scaly anteater,' is a widely trafficked mammal, prized in some cultures for its meat and scales. Little is known about these animals, and raising rescued... more
Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their... more
More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high... more
The number of malnourished people is increasing worldwide. More than two billion people suffer from a lack of micronutrients. Infant mortality rates are unacceptably high. Against this background, there is a need... more
Necrotizing enterocolitis (NEC) is a devastating intestinal disease that occurs primarily in premature infants. We performed genome-resolved metagenomic analysis of 1163 fecal... more
Long noncoding RNAs (lncRNAs) are important regulators of diverse biological processes; however, their function in macrophage activation is undefined. We... more
Systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE) of the skin are autoimmune diseases characterized by inappropriate immune responses against self-proteins;... more
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with a median 5-year survival of ~20%. Current U.S. Food and Drug Administration–approved pharmacotherapies slow progression of IPF, providing hope... more
Participants who ate a diet high in red and processed meat, fried food, refined grains and high-fat dairy were three times more likely to develop an... more
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array... more
The endangered Sunda pangolin, or "scaly anteater," is a widely trafficked mammal, prized in some cultures for its meat and scales. Little is known about these animals, and raising rescued... more
Sharks play a critical role in keeping oceans healthy, balancing the food chain and ensuring species diversity. However, the demand for shark derivatives has led to their exploitation, often without... more
Several countries are building futuristic communication systems using higher frequency electromagnetic waves to transfer more data at faster rates, but they have lacked network components to handle these higher bandwidths. A researcher has now demonstrated that... more
New research from anthropologists at McMaster University and California State University, San Bernardino (CSUSB), is shedding light on ancient dietary practices, the evolution of agricultural societies and ultimately, how plants... more
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across... more
Sea ice in the Bering Sea shrank to its lowest levels in recorded history in 2018, profoundly affecting northwest Alaska residents who depend on marine resources... more
Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to... more
Warm waters are a threat to cold water fish like salmon and trout. But a study led by researchers at University of California, Davis suggests that habitats with abundant food... more
Researchers at Leiden University and TU Delft have combined two techniques that are used to measure the structure of biomolecules, creating a method that is 10 times more sensitive. With... more
Ziath has launched a competitively priced starter kit for organizations involved in food research, production and testing to keep track of samples to help improve food... more
A United Nations report says nearly a half-billion people in the Asia-Pacific are still malnourished and to achieve a goal of zero hunger by 2030 requires that millions escape food... more
Effectiveness in preventing or treating serious medical conditions typically requires patients to follow treatment plans such as medication, exercise or diet, but about 50 percent of... more
Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella... more
Aging adults are more likely to have - and die from - cardiovascular disease than their younger counterparts. New basic science research finds reason to link... more
Gastric intestinal metaplasia (GIM), which is linked to non-cardia gastric cancer, is often detected during routine endoscopy, leading to questions about how patient care should be... more