CRISPR
Researchers working on simple, low-cost CRISPR-based diagnostic test for infectious diseases  PHYS.ORG · 7 days
Researchers in the Department of Biomedical Engineering— a shared department in the schools of Dental Medicine, Medicine, and Engineering—have been working to develop a new, low-cost,... more
Capabilities of CRISPR gene editing expanded  PHYS.ORG · 7 days
Many basic and clinical researchers are testing the potential of a simple and efficient gene editing approach to study and correct disease-causing mutations for conditions ranging from blindness to cancer, but the technology is constrained by... more
Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants  Science Magazine · 1 week
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove this constraint, we engineered variants of... more
Finding new treatments for muscular dystrophy with CRISPR-Cas9  NEWS MEDICAL · 1 week
A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and... more
[Research Articles] Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy  Science Magazine · 1 week
The emergence of CRISPR-Cas9 gene-editing technologies and genome-wide CRISPR-Cas9 libraries enables efficient unbiased genetic screening that can accelerate the process of therapeutic... more
Humans are not the first to exploit benefits of CRISPR technique, research shows  NEWS MEDICAL · 1 week
In recent years, the development of CRISPR technologies and gene-editing scissors in particular have taken the world by storm. Indeed, scientists have... more
Research breakthrough: Humans are not the first to repurpose CRISPR  SCIENCE DAILY · 1 week
We humans are far from the first to exploit the benefits of CRISPR. Groundbreaking research has helped to redefine what CRISPR is. Researchers have discovered that primitive bacterial... more
Humans are not the first to repurpose CRISPR  PHYS.ORG · 1 week
In recent years, the development of CRISPR technologies and gene-editing scissors in particular have taken the world by storm. Indeed, scientists have learned how to harness these clever natural systems in the... more
Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain  Science Magazine · 2 weeks
A genome editing technique based on the clustered regularly interspaced short palindromic repeats (CRISPR)–associated endonuclease Cas9 enables efficient... more
New kind of CRISPR technology to target RNA, including RNA viruses like coronavirus  SCIENCE DAILY · 2 weeks
Researchers have developed a new kind of CRISPR screen technology to target RNA. The team leveraged their technology for a critical analysis:... more
New kind of CRISPR technology to target RNA, including RNA viruses like coronavirus  nanowerk · 2 weeks
New genetic screening platform using CRISPR technology for targeting thousands of genes in a massively-parallel fashion; accurate and fast method of finding... more
Researchers develop new kind of CRISPR screen technology to target RNA  NEWS MEDICAL · 3 weeks
CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases. more
New kind of CRISPR technology to target RNA, including RNA viruses like coronavirus  PHYS.ORG · 3 weeks
CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many... more
Cleaving through the heart of viral infections  PHYS.ORG · 3 weeks
A novel CRISPR/Cas system that can efficiently attack and destroy several prolific plant viruses has been developed by KAUST using tobacco plants and is now being extended to rice and other crops. more
Fight for Sight funded researcher develops gene therapy approach for glaucoma  NEWS MEDICAL · 3 weeks
A Fight for Sight funded researcher from the University of Bristol has used gene editing techniques to successfully demonstrate a gene therapy for glaucoma in the... more
CRISPR-Cas system can be used to effectively target colitis pathogen  NEWS MEDICAL · 3 weeks
Research at North Carolina State University shows that the CRISPR-Cas system can be used to effectively target and eliminate specific gut bacteria, in this case Clostridioides difficile, the... more
Researchers establish new viable CRISPR-Cas12b system for plant genome engineering  PHYS.ORG · 4 weeks
In a new publication in Nature Plants, assistant professor of Plant Science at the University of Maryland Yiping Qi has established a new CRISPR genome engineering system as... more
Pervasive functional translation of noncanonical human open reading frames  Science Magazine · 4 weeks
Ribosome profiling has revealed pervasive but largely uncharacterized translation outside of canonical coding sequences (CDSs). In this work, we exploit a systematic CRISPR-based screening strategy to identify hundreds of noncanonical... more
Genome editing strategy could improve rice, other crops  PHYS.ORG · 4 weeks
Scientists at UC Davis have used CRISPR technology to genetically engineer rice with high levels of beta-carotene, the precursor of vitamin A. The technique they used provides a promising strategy for genetically... more
Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs  Science Magazine · 4 weeks
The rapid evolution of resistance alleles poses a major obstacle for genetic manipulation of populations with CRISPR homing gene drives. One proposed... more
News Brief: Election Results, Stock Markets Drop, Gene-Editing Tool  NPR · 1 month
After Super Tuesday, Joe Biden and Bernie Sanders are the front-runners. U.S. financial markets fell again on concerns over the coronavirus outbreak. And, details of a new development in medicine. more
In A 1st, Scientists Use Revolutionary Gene-Editing Tool To Edit Inside A Patient  NPR · 1 month
Doctors used CRISPR to edit genes of cells inside a patient's eye, hoping to restore vision to a person blinded by a... more
Doctors try 1st CRISPR editing in the body for blindness  ABC NEWS · 1 month
Scientists say they have used the gene editing tool CRISPR inside someone's body for the first time more
Improved CRISPR gene drive solves problems of old tech  PHYS.ORG · 1 month
Gene drives use genetic engineering to create a desired mutation in a few individuals that then spreads via mating throughout a population in fewer than 10 generations. more
DNAGene EditingGeneticsGMOBiologyMicrobiology
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