Adults carrying a gene associated with a higher risk of Alzheimer's disease had a harder time accessing recently acquired knowledge, even though they didn't... more
Many biological materials form via liquid-liquid phase separation (LLPS), followed by maturation into a solid-like state. Here, using a biologically inspired assembly mechanism designed to recapitulate... more
Cell-cell communication plays a pivotal role in coordination and function of biological systems. Three-dimensional (3D) spheroids provide venues to explore cellular communication for tissue... more
Southern California developers have long sought relief from regulations protecting wildlife, and earlier this month the Trump administration obliged, formally... more
When energy is added to uranium under pressure, it creates a shock wave, and even a tiny sample will be vaporized like a small explosion. By using smaller, controlled explosions, physicists can... more
How do cells generate and use energy? This question might seem simple, but the answer is far from simple. Furthermore, knowing how microbial cell factories consume energy and how proteins are allocated to do so is... more
Most people will have seen at least one headline over the last couple of years describing animal attacks on humans. This needn't include the elephant from... more
Food scientists have shown that feeding frying oil to mice exaggerated colonic inflammation, enhanced tumor growth and worsened gut leakage, spreading bacteria or toxic... more
Biologists have shed new light on a crucial aspect of the plant immune response. Their discovery, revealing how plant resistance proteins trigger localized cell death, could lead to new strategies for engineering... more
In the first continent-wide genomic study of malaria parasites in Africa, scientists have uncovered the genetic features of Plasmodium falciparum parasites that inhabit different... more
Pollen-borne microbes represent an important protein source for larval bees, according to new research. Of the more than 20,000 species of bees... more
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide... more
The first detailed map of individual malaria parasite behavior across each stage of its complicated life cycle has been created by scientists. Researchers used advanced single-cell technology to isolate individual parasites and... more
Western pond turtles got fatter and healthier after scientists removed nearly 200 invasive red-eared slider turtles from the UC Davis Arboretum, reports a new study. The study is the first to quantify... more
In what likely is the first study on the evolution of dietary preferences across the animal kingdom, researchers report several unexpected discoveries, including that the first animal likely was a... more
An experiment from The Australian National University (ANU) using artificial trees has attracted birds and other wildlife never before seen in a damaged Canberra landscape—catching them on camera at the... more
The World Health Organization's emergencies chief said the ongoing Ebola outbreak in Congo is approaching a "stark" milestone with nearly 2,000 people killed by the virus in the... more
An international group of scientists studied the effects of 17 lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal Cell Metabolism. more
The South Australian government recently announced its intention to lift the long-standing statewide moratorium on genetically modified (GM) crops, following a statutory... more
Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be... more
A global study comparing 2,062 birds finds that, in highly variable environments, birds tend to have either larger or smaller brains relative to their body size. Birds with smaller brains tend to use ecological... more
Researchers have proposed a way to measure the ecological impact of global food wastage due to excessive consumption. The results suggest that direct food waste --... more
The CRISPR genome-editing system is best-known for its potential to correct disease-causing mutations and add new genes into living cells. Now, a team from MIT and Harvard University has deployed CRISPR for... more
It's no secret crows are smart. They're notorious for frustrating attempts to keep them from tearing into garbage cans; more telling, however, is that they are one of the few... more
In the southern Atlantic Rainforest remnants between Rio de Janeiro State in Southeast Brazil and Santa Catarina State in South Brazil, there are some 600 species... more
Public health experts in the US have discovered that the Zika virus may still be spreading in the Americas, despite case reporting having approached close to zero. more
With every unfinished meal since Band Aid, you've heard it: "people are starving in Africa, y'know". True, the UN estimates that rich countries throw... more
They're physically and emotionally wounded – most likely suffering from post-traumatic stress. Members of the United States military who serve abroad often return to the U.S. to treat... more
Veterinarians have successfully harvested eggs from the last two surviving northern white rhinos, taking them one step closer to bringing the species back from the brink... more
Big brains can help an animal mount quick, flexible behavioral responses to frequent or unexpected environmental changes. But some birds just don't need 'em. more
Environmental conditions influence our body mass index by increasing or decreasing the effect of inherited genetic variations, University of Queensland researchers have discovered. more
The phase 1 clinical trial will test the feasibility and safety of CAR-T cells - genetically modified white blood cells harvested from a patient's own blood with the unique ability to directly attack and kill cancers... more
For the first time, scientists built a synthetic biologic system with compartments like real cells. This Army project at the University of Massachusetts Amherst... more
With every unfinished meal since Band Aid, you've heard it: "people are starving in Africa, y'know". True, the UN estimates that rich countries throw away nearly... more
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies... more
In the first continent-wide genomic study of malaria parasites in Africa, scientists have uncovered the genetic features of Plasmodium falciparum parasites that... more
Researchers at the University of North Carolina Chapel Hill and RTI International, a nonprofit research institute, recently found that patients with early rheumatoid arthritis (RA) may... more
Scientists in Florida have artificially induced reproductive spawning of an endangered Atlantic coral species for the first time in an aquarium setting, a breakthrough... more
The cryoEM structure of a simian immunodeficiency virus protein bound to primate proteins shows how a mutation in early humans allowed our ancestors to escape infection while monkeys and apes did not. SIV's Nef... more
Over the last 40 years, the Asian tiger mosquito, Aedes albopictus, has invaded every continent thanks to the transportation of its eggs via human trade and... more
Animal-assisted therapy has many benefits in health care. Yet, its biological and psychosocial effects in the military are unknown, especially for injured, airlifted patients. Researchers teamed up with... more
Adults carrying a gene associated with a higher risk of Alzheimer's disease had a harder time accessing recently acquired knowledge, even though they didn't show any... more
A new computational tool called ProtFus screens scientific literature to validate predictions about the activity of fusion proteins -- proteins encoded by the joining of two genes that previously encoded... more
An international team of researchers who analyzed data across multiple ethnicities has produced the largest genetic study to date associated with common childhood obesity. more
Microbiomes aren't just for understanding and modulating gut health - skin, our largest organ, hosts a vibrant and complex microbiome that can provide health insights. An international research team has... more
A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with... more
A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the... more
A team of researchers from Rensselaer Polytechnic Institute and the University of Texas Austin has used a new technique to analyze tiny amounts of... more
Host cell metabolism can be modulated by viral infection, affecting viral survival or clearance. The cellular metabolism rewiring mediated by N6-methyladenosine (m6A) modification in virus-host interaction remains largely unknown. Here... more
SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of nicotinamide adenine dinucleotide in its oxidized form (NAD+) during... more
Stimuli-responsive materials activated by biological signals play an increasingly important role in biotechnology applications. We exploit the programmability of CRISPR-associated nucleases to actuate hydrogels containing DNA as a structural element or as an anchor for pendant groups. After activation by... more
Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We... more
Membraneless organelles involved in RNA processing are biomolecular condensates assembled by phase separation. Despite the important role of intrinsically disordered protein regions... more
Soil organisms represent the most biologically diverse community on land and govern the turnover of the largest organic matter pool in the terrestrial biosphere. The highly complex nature of these... more
A new computational tool called ProtFus screens scientific literature to validate predictions about the activity of fusion proteins—proteins encoded by the joining of two genes that previously encoded two separate... more
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide... more
The first detailed map of individual malaria parasite behaviour across each stage of its complicated life cycle has been created by scientists. Researchers at the Wellcome Sanger Institute and their collaborators used... more
Cells rely on protein complexes known as ATP synthases or ATPases for their energy needs. Adenosine triphosphate (ATP) molecules power most of the processes sustaining life. Structural biologist Professor Leonid Sazanov and his research group from the Institute... more
Plants, like humans and animals, have over millions of years evolved complex immune systems that fend off invading pathogens. But unlike many animals, plants lack adaptive immunity conferred by antibodies. This means... more
The function of the visual photopigment rhodopsin and its action in the retina to facilitate vision is well understood. However, there remain questions about other biological functions of this family of proteins... more
US environmental groups have sued the administration of President Donald Trump over rollbacks that weaken the Endangered Species Act, a law credited with saving iconic species from the bald eagle to the... more
Coordinated observations of Jupiter in early 2017 by six ground-based telescopes and Hubble allowed astronomers to study the evolution of bright plumes and connect them with cloud movements deep in... more
Researchers may have found a way to reverse falling crop yields caused by increasingly salty farmlands throughout the world. Scientists have used bacteria found in the roots of salt-tolerant plants to successfully... more
The function of the visual photopigment rhodopsin and its action in the retina to facilitate vision is well understood. However, there remain questions about other biological functions of this family of proteins (opsins) and this has ramifications for... more
Researchers found that Charles Darwin's famous finches defy what has long been considered a key to evolutionary success: genetic diversity. The study of the finches of the Galapagos Islands could change the way conservation biologists think... more
First head-to-head comparison of CDK4/6 inhibitors in cell line and animal models of breast cancer reveals important differences, including one drug that exhibits unique, potentially advantageous... more
By sequencing virus genomes from infected travelers, analyzing travel patterns and mosquito modeling, researchers unearthed a spike in Zika cases from travelers returning from... more
Researchers have created a technology called DOMINO to store complex 'memories' in the DNA of living cells, including human cells. This memory storage capacity can form the foundation of complex circuits that trigger a... more
Wildlife-supporting countries on Thursday backed regulating international trade in giraffes in a bid to offer more protection to the gentle giants, feared to be facing a "silent extinction". more
Hundreds of Spanish livestock farmers staged a protest Thursday in the Pyrenees town of Ainsa against the re-introduction of brown bears to the mountain region saying the predators are a menace to... more
Bacteria grow everywhere, including inside the International Space Station. That is why ESA has selected the Luxembourg Institute of Science and Technology (LIST) to... more
At an unprecedented scale, researchers have now cataloged the array of surveillance tools that plants use to detect disease-causing microbes across an entire species. Representing a... more
Microbial life on Mars may potentially be transported across the planet on dust particles carried by wind, according to a study conducted in the Atacama Desert in North... more
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