PHYS.ORG A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, developed by a team of researchers at Penn State, and the shared characteristics of these proteins are described in a paper that appears online on July 12th in the journal Molecular Cell. 3 days
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One step closer to finding a cure for brain diseases
SCIENCE DAILY Researchers have identified a mechanism for signaling brain nerve cells through excitatory synaptic binding proteins. The finding provides important clues to understanding the principles of synaptic nerve transmission... 2 days
Supercoil me! The art of knotted DNA maintenance
SCIENCE DAILY Locking DNA knots in place thanks to DNA propensity to be supercoiled. A new study suggests that is one of the mechanisms that could be harnessed by the cellular machinery to deal... 1 week
Off/on switch for DNA repair protein
SCIENCE DAILY Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now researchers have determined how one DNA repair protein gets to the site of DNA damage. The authors say they... 2 weeks
Supercoil me! The art of knotted DNA maintenance
PHYS.ORG Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. Researchers now suggest that the DNA propensity to... 1 week
Scientists decipher the structure, key features of a critical immune-surveillance protein in humans
PHYS.ORG The human body is built for survival. Each one of its cells is closely guarded by a set of immune proteins armed... 3 days
Scientists identify structural and functional differences in human immune-surveillance protein
NEWS MEDICAL The human body is built for survival. Each one of its cells is closely guarded by a set of immune proteins armed with nearly foolproof radars that detect... 2 days
Mayo researchers find off/on switch for DNA repair protein
PHYS.ORG Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers... 2 weeks
Researchers find new way for producing medical therapeutic proteins
NEWS MEDICAL Bacterial systems are some of the simplest and most effective platforms for the expression of recombinant proteins. 3 days
Electrical disorder acts like a traffic light for a biological gate
SCIENCE DAILY Nature's way of allowing proteins across its gates, through porous biological membranes, depends, among others, on their electrical charge. Scientists have now uncovered how the mixed... 2 weeks
New assay reveals biophysical properties that allow certain proteins to infect others
SCIENCE DAILY Scientists have identified a physical basis for the spread of corrupted proteins known as prions inside cells. 1 week
Mayo researchers determine how DNA repair protein gets to the site of damage
NEWS MEDICAL Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published... 2 weeks
DNA-induced liquid phase condensation of cGAS activates innate immune signaling
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Hi-res image of structure of the origin recognition complex bound to DNA revealed
PHYS.ORG Cells propagate by making copies of themselves via genome replication. Arguably, replication of DNA is the most fundamental and conserved mechanism of... 1 week
Electrical disorder acts like a traffic light for a biological gate
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Crime scene DNA could be used to reveal a suspect’s age—and whether they have cancer
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Rethinking neurodegenerative disease treatment: Target multiple pathological proteins
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The secret sulfate code that lets the bad Tau in
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Targeting multiple proteins may be key to treat neurodegenerative disorders
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New technologies for producing medical therapeutic proteins
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Simple DNA test can predict risk of bad side effects to thiopurine drugs
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A chaperonin protein, GroEL, has a more complex mechanism than was thought before
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The 'shine' in gold particles has a new use – finding defects
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New assay reveals biophysical properties that allow certain proteins to infect others
PHYS.ORG Scientists at the Stowers Institute for Medical Research have identified a physical basis for the spread of corrupted proteins known as prions inside cells.... 1 week
Honeybees finding it harder to eat at America's bee hot spot
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How antifreeze proteins stop ice cold
PHYS.ORG How do insects survive harsh northern winters?  Unlike mammals, they don't have thick coats of fur to keep warm.  But they do have antifreeze. Antifreeze proteins (AFPs) prevent ice from forming and spreading inside their bodies. 6 days
Screening a tiny section of DNA to avoid severe reactions to some meds
SCIENCE DAILY Researchers have found that a simple DNA test can predict if East Asian patients are likely to have bad reactions to thiopurine... 2 weeks
New method discovered to view proteins inside human cells
PHYS.ORG Scientists at the University of Warwick have created a new way to view proteins that are inside human cells. 2 weeks
New method discovered to view proteins inside human cells
SCIENCE DAILY Scientists have created a new way to view proteins that are inside human cells. 1 week
Researchers discover a way to peer inside proteins to see how they are wired
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Ancient DNA testing solves 100-year-old controversy in Southeast Asian prehistory
SCIENCE DAILY Two competing theories about the human occupation of Southeast Asia have been debunked by groundbreaking analysis of ancient DNA extracted from 8,000-year-old skeletons. 1 week
The 'shine' in gold particles has a new use – finding defects
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Can airships take scenic flights back to the future?
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Scientists show how energy landscape algorithm details DNA's interphase dynamics
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Berry-gorging bears disperse seeds through scat and feed small mammals
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