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Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism
NEWS MEDICAL Discovered more than two decades ago, the hormone leptin has been widely hailed as the key regulator of leanness. Yet, the pivotal... 19 hours
Newly discovered antibiotic could help treat drug-resistant tuberculosis
NEWS MEDICAL A newly discovered antibiotic, produced by bacteria from a cystic fibrosis patient, could be used to treat cases of drug-resistant tuberculosis (TB). This is the finding of a team of scientists from... 1 day
MSU researcher developing new miniature models to study heart disease and sickle cell anemia
NEWS MEDICAL A Mississippi State University researcher is developing new miniature models to better understand the factors that lead to heart disease... 2 days
Custom built molecule shows promise as anti-cancer therapy
SCIENCE DAILY Scientists have custom-built a molecule which stops breast cancer cells from multiplying in laboratory trials, and hope it will eventually lead to a treatment for the disease. 2 days
New insight into a central biological dogma on ion transport
SCIENCE DAILY New research results show how active transport of potassium can be achieved by a membrane protein complex that has roots in both ion pump and ion channel super-families.... 2 days
Genes, ozone, and autism
SCIENCE DAILY Exposure to ozone in the environment puts individuals with high levels of genetic variation at an even higher risk for developing autism than would be expected just by adding the two risk factors together, a new analysis shows. The study... 2 days
Donor SIRP{alpha} polymorphism modulates the innate immune response to allogeneic grafts
Science Magazine Mice devoid of T, B, and natural killer (NK) cells distinguish between self and allogeneic nonself despite the absence of an adaptive immune system. When challenged... 2 days
Electronic structure of aqueous solutions: Bridging the gap between theory and experiments
Science Magazine Predicting the electronic properties of aqueous liquids has been a long-standing challenge for quantum mechanical methods. However, it is a crucial step in understanding... 2 days
Plants sacrifice 'daughters' to survive chilly weather
SCIENCE DAILY Plants adopt different strategies to survive the changing temperatures of their natural environments. This is most evident in temperate regions where forest trees shed their leaves to conserve energy during the cold season. In... 2 days
Medical News Today: Plant fats alter gut bacteria to ease Crohn's symptoms
MNT A diet high in coconut oil and other plant-derived fats may alter gut bacteria diversity, reducing gut inflammation for patients with Crohn's disease. 2 days
Kansas jury awards $218M to farmers in Syngenta GMO suit
PHYS.ORG A Kansas federal jury awarded nearly $218 million on Friday to farmers who sued Swiss agribusiness giant Syngenta over its introduction of a genetically engineered corn seed variety. 2 days
Plant fats alter gut bacteria to ease Crohn's symptoms
MNT A diet high in coconut oil and other plant-derived fats may alter gut bacteria diversity, reducing gut inflammation for patients with Crohn's disease. 2 days
Tiny nanoparticles offer significant potential in detecting, treating disease new review of work on exosomes
SCIENCE DAILY Exosomes - tiny biological nanoparticles which transfer information between cells - offer significant potential in detecting and treating... 2 days
Combined molecular biology test is the first to distinguish benign pancreatic lesions
SCIENCE DAILY When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely... 2 days
Fungal toxins easily become airborne, creating potential indoor health risk
PHYS.ORG Toxins produced by three different species of fungus growing indoors on wallpaper may become aerosolized, and easily inhaled. The findings, which likely have implications for "sick building syndrome,"... 2 days
Ancient Egyptians to modern humans: Coronary artery disease genes benefit reproduction
SCIENCE DAILY Researchers have found that genes for coronary heart disease (CAD) also influence reproduction, so in order to reproduce successfully, the genes for heart disease will also... 2 days
Researchers uncover novel mechanism involved in cancer cell migration
NEWS MEDICAL Supervised by Guillaume Montagnac, Inserm research leader at Gustave Roussy, in collaboration with the Institut Curie and the Institut de Myologie, this research, is published in the 16th June issue... 2 days
Microbe generates extraordinarily diverse array of peptides
MIT In marine bacteria, evolution of new specialized molecules follows a previously unknown path. 2 days
Two-test combination accurately identifies benign pancreatic lesions
NEWS MEDICAL When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. 2 days
Discovery of a new mechanism involved in the migration of cancer cells
PHYS.ORG VIDEO A team of young French researchers has discovered a new mechanism which facilitates cell migration. On the surface of its membrane, the cell develops... 2 days
Dune ecosystem modelling
PHYS.ORG Acacia longifolia, which is native to Australia, is a species which was cultivated in Portugal primarily to stabilize dunes and as an ornamental plant; now it has spread out uncontrollably in Portugal and into many ecosystems around the world. This... 2 days
The Gulf of Mexico's 'Dead Zone' Could Nearly Double in Size This Year
LIVE SCIENCE Agricultural runoff and biological waste from the Mississippi River fuel algae blooms each year in the Gulf of Mexico, depleting marine oxygen... 2 days
Existing drugs could benefit patients with bone cancer, genetic study suggests
SCIENCE DAILY A subgroup of patients with osteosarcoma -- a form of bone cancer -- could be helped by an existing drug, suggest scientists. In the largest genetic... 2 days
Tropical viruses: Coming soon to Europe?
SCIENCE DAILY The mosquito-borne viral disease Chikungunya is usually found in tropical areas. Researchers have now discovered how climate change is facilitating the spread of the Chikungunya virus. Even if climate change only progresses moderately – as scientists... 2 days
Lipoprotein abnormalities linked to vaso-occlusive events in patients with sickle cell disease
NEWS MEDICAL An article published in Experimental Biology and Medicine (Volume 242, Issue 12, June, 2017) links imbalances in lipoprotein metabolism with vaso-occlusive events in patients... 2 days
Protein mingling under blue light
SCIENCE DAILY One of the current challenges in biology is to understand rapidly-changing phenomena. Interestingly, only a small fraction of them is due to proteins acting in isolation, the majority of biological events are regulated by proteins acting together in... 2 days
How a single chemical bond balances cells between life and death
SCIENCE DAILY With SLAC's X-ray laser and synchrotron, scientists measured exactly how much energy goes into keeping a crucial chemical bond from triggering a cell's death spiral. 2 days
Tiny biological nanoparticles offer enormous potential for diagnostic and therapeutic applications
NEWS MEDICAL Exosomes - tiny biological nanoparticles which transfer information between cells - offer significant potential in detecting and treating disease, the most comprehensive overview so far of research in... 2 days
Better cell factories for the drugs of the future
PHYS.ORG Pharmaceuticals based on proteins are promising candidates for the treatment of cancer and other severe diseases, but they can be hard to produce. In a new research project, Chalmers researchers... 2 days
Protein mingling under blue light
PHYS.ORG One of the current challenges in biology is to understand rapidly-changing phenomena. Interestingly, only a small fraction of them is due to proteins acting in isolation, the majority of biological events are regulated by proteins acting together in... 2 days
Magnetic nanoknots evoke Lord Kelvin's vortex theory of atoms
PHYS.ORG (Phys.org)—In the late 1800s when scientists were still trying to figure out what exactly atoms are, one of the leading theories, proposed by Lord Kelvin, was that atoms are knots... 2 days
A unique amino acid for brain cancer therapy
SCIENCE DAILY Photodynamic therapy is often used to treat brain tumors because of its specificity — it can target very small regions containing cancerous cells while sparing the normal cells around it from damage.... 2 days
OIST researchers create taurine-modified photosensitizer for brain cancer therapy
NEWS MEDICAL Photodynamic therapy is often used to treat brain tumors because of its specificity—it can target very small regions containing cancerous cells while sparing the normal cells around it from damage.... 2 days
Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton
NEWS MEDICAL The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It... 2 days
Plants sacrifice 'daughters' to survive chilly weather
PHYS.ORG Plants adopt different strategies to survive the changing temperatures of their natural environments. This is most evident in temperate regions where forest trees shed their leaves to conserve energy during the cold season. In... 2 days
A single electron's tiny leap sets off 'molecular sunscreen' response
PHYS.ORG In experiments at the Department of Energy's SLAC National Accelerator Laboratory, scientists were able to see the first step of a process that protects a DNA building block... 2 days
from strands to droplets new insights into dna control From strands to droplets—new insights into DNA control
PHYS.ORG VIDEO A host of proteins and other molecules sit on the strands of our DNA, controlling which genes are read out and used by cells and which remain silent. This aggregation of genetic... 2 days
Jellyfish fluorescence shines new light on DNA copying
PHYS.ORG Scientists at the University of York have used florescent proteins from jellyfish to help shed new light on how DNA replicates. 2 days
In marine bacteria, evolution of new specialized molecules follows a previously unknown path
PHYS.ORG It's one of the tiniest organisms on Earth, but also one of the most abundant. And now, the microscopic marine bacteria called... 2 days
Researchers identify new way to effectively kill cancer stem cells using existing drugs
NEWS MEDICAL A team of researchers at McMaster University has identified a unique feature of cancer stem cells that can be exploited to kill... 2 days
Cancer cells may lose copies of ribosomal DNA to enable faster proliferation, study shows
NEWS MEDICAL Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. 2 days
China tightens online video controls, jolting investors
PHYS.ORG Three popular Chinese internet services have been ordered to stop streaming video after censors complained it contained improper comments on sensitive issues. The move prompted a sell-off in the U.S.-traded shares of Sina Corp.... 2 days
Researchers identify first definitive risk genes for Tourette Syndrome
NEWS MEDICAL An international team that just conducted the largest study of Tourette Syndrome has identified genetic abnormalities that are the first definitive risk genes for the disorder. 3 days
Microbe generates extraordinarily diverse array of peptide
MIT In marine bacteria, evolution of new specialized molecules follows a previously unknown path. 3 days
Wasp venom provides clues to how genes take on new functions
NEWS MEDICAL Amid the incredible diversity of living things on our planet, there is a common theme. Organisms need to acquire new genes, or change the functions of... 3 days
Human colon organoids fill gap in effectively modeling common GI diseases
NEWS MEDICAL Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according... 3 days
Which animal is most likely to spread the latest plague?
NEWS MEDICAL There are a large number of infections that are borne and carried by animals and spread to humans. These are called zoonotic diseases wherein the microbe or pathogen... 3 days
New efficient, low-temperature catalyst for hydrogen production
SCIENCE DAILY Scientists have developed a new low-temperature catalyst for producing high-purity hydrogen gas while simultaneously using up carbon monoxide (CO). The discovery could improve the performance of fuel cells that run on hydrogen fuel but... 3 days
Biologist develops new method to calculate populations of elusive species
SCIENCE DAILY An innovative new method of estimating the density of snake populations without employing the capture-mark-recapture technique has been created by a biologist. 3 days
An enzyme to synthetize carbohydrates designed
SCIENCE DAILY Sugar or carbohydrate synthesis is important for the development of diagnostic tests, vaccines and new drugs. In a study, researchers have synthesized carbohydrates with enzymes through a reaction that was not much studied so far on... 3 days
Melanoma: Symptoms, Treatment and Prevention
LIVE SCIENCE Melanoma is a type of skin cancer that begins in the skin's pigment-producing cells, called melanocytes. These cells make melanin, which is responsible for the color in skin, eyes and hair. 3 days
First Chikungunya-infected Aedes aegypti mosquitoes found in Brazil
SCIENCE DAILY While more than 13,000 cases of Chikungunya viral disease were reported in Brazil in 2015, scientists had never before detected the virus in a captured mosquito in this country. Now, researchers have... 3 days
The biology of uterine fluid: How it informs the fetus of mom's world
SCIENCE DAILY A developing fetus bathes in a mixture of cellular secretions and proteins unique to its mother's uterus. Before fertilization, the pH of... 3 days
Is There a Link Between Having Children and Heart Disease?
LIVE SCIENCE Some of the genes that up your risk of heart disease are also linked with having more kids, a new study finds. 3 days
How eggs got their shapes
SCIENCE DAILY The evolution of the amniotic egg -- complete with membrane and shell -- was key to vertebrates leaving the oceans and colonizing the land and air but how bird eggs evolved into so many different shapes and sizes... 3 days
Lab grown human colons change study of GI disease
SCIENCE DAILY Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to new research. The... 3 days
How bacterial organelles assemble
SCIENCE DAILY Scientists are providing the clearest view yet of an intact bacterial microcompartment, revealing at atomic-level resolution the structure and assembly of the organelle's protein shell. This work could benefit research in bioenergy and pathogenesis, and it could lead to new... 3 days
Human genes for coronary artery disease make them more prolific parents
SCIENCE DAILY Coronary artery disease may have persisted in human populations because the genes that cause this late-striking disease also contribute to having a greater numbers of children. 3 days
How do genes get new jobs? Wasp venom offers new insights
SCIENCE DAILY A new study describes how four closely related species of parasitic wasps change their venoms rapidly in order to adapt to new hosts, and proposes that... 3 days
Better use of current drugs to target cancer
SCIENCE DAILY Researchers worked backwards, employing a series of drugs used in the clinic to understand a new way that cancer stem cells can be killed. 3 days
How eggs got their shapes: Adaptations for flight may have driven egg-shape variety in birds
PHYS.ORG The evolution of the amniotic egg—complete with membrane and shell—was key to vertebrates leaving the oceans and colonizing... 3 days
Simulated honeybees can use simple brain circuits for complex learning
PHYS.ORG Honeybees may not need key brain structures known as mushroom bodies in order to learn complex associations between odors and rewards, according to new research published in PLOS... 3 days
New efficient, low-temperature catalyst for hydrogen production
PHYS.ORG Scientists have developed a new low-temperature catalyst for producing high-purity hydrogen gas while simultaneously using up carbon monoxide (CO). The discovery-described in a paper set to publish online in the journal Science on Thursday,... 3 days
Switchable DNA mini-machines store information
PHYS.ORG Biomedical engineers have built simple machines out of DNA, consisting of arrays whose units switch reversibly between two different shapes. 3 days
wasp venom holds clues on how genes get new jobs Wasp venom holds clues on how genes get new jobs
PHYS.ORG VIDEO Amid the incredible diversity of living things on our planet, there is a common theme. Organisms need to acquire new genes, or change the functions of existing genes,... 3 days
Researchers find way to better use current drugs to target cancer
SCIENCE DAILY Researchers worked backwards, employing a series of drugs used in the clinic to understand a new way that cancer stem cells can be killed. 3 days
High fat diet reduces gut bacteria, Crohn's disease symptoms
SCIENCE DAILY A high fat diet may lead to specific changes in gut bacteria that could fight harmful inflammation -- a major discovery for patients suffering from Crohn's disease, research indicates. Crohn's... 3 days
Rare cells are 'window into the gut' for the nervous system
SCIENCE DAILY Specialized cells in the gut sense potentially noxious chemicals and trigger electrical impulses in nearby nerve fibers, according to a new study, report scientists. 3 days
Scientists spy on the secret inner life of bacteria
SCIENCE-NEWS New images reveal the inner workings of bacteria. 3 days
Memories stored in same neuron can be selectively erased, study suggests
NEWS MEDICAL Different types of memories stored in the same neuron of the marine snail Aplysia can be selectively erased, according to a new study by researchers at... 3 days
ISU entomologist urges summertime precautions against mosquitoes and ticks
NEWS MEDICAL Ryan Smith, an assistant professor of entomology at Iowa State University is encouraging Iowans to take precautions this summer when spending time outdoors in areas commonly populated by mosquitoes and ticks, which... 3 days
Reconfiguration of DNA molecular arrays driven by information relay
Science Magazine Information relay at the molecular level is an essential phenomenon in numerous chemical and biological processes, such as intricate signaling cascades. One key challenge in synthetic molecular self-assembly is to... 3 days
Atomic-layered Au clusters on {alpha}-MoC as catalysts for the low-temperature water-gas shift reaction
Science Magazine The water-gas shift (WGS) reaction (CO+H2O=H2+CO2) is an essential process for hydrogen generation and CO removal in various energy-related chemical operations. This... 3 days
Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell
Science Magazine Many bacteria contain primitive organelles composed entirely of protein. These bacterial microcompartments share a common architecture of an enzymatic core encapsulated in a selectively permeable protein shell; prominent... 3 days
Building chromosomes without bricks
Science Magazine 3 days
A catalytic fluoride-rebound mechanism for C(sp3)-CF3 bond formation
Science Magazine The biological properties of trifluoromethyl compounds have led to their ubiquity in pharmaceuticals, yet their chemical properties have made their preparation a substantial challenge, necessitating innovative chemical solutions. We report the serendipitous... 3 days
How much does a virus cost?
Science Magazine 3 days
Quantum and isotope effects in lithium metal
Science Magazine The crystal structure of elements at zero pressure and temperature is the most fundamental information in condensed matter physics. For decades it has been believed that lithium, the simplest metallic element, has a complicated... 3 days
A global brain state underlies C. elegans sleep behavior
Science Magazine How the brain effectively switches between and maintains global states, such as sleep and wakefulness, is not yet understood. We used brainwide functional imaging at single-cell resolution to show that... 3 days
Avian egg shape: Form, function, and evolution
Science Magazine Avian egg shape is generally explained as an adaptation to life history, yet we currently lack a global synthesis of how egg-shape differences arise and evolve. Here, we apply morphometric, mechanistic, and macroevolutionary analyses... 3 days
Small RNA retunes photosynthesis
Science Magazine 3 days
Chemical transformation of xenobiotics by the human gut microbiota
Science Magazine The human gut microbiota makes key contributions to the metabolism of ingested compounds (xenobiotics), transforming hundreds of dietary components, industrial chemicals, and pharmaceuticals into metabolites with altered activities, toxicities, and... 3 days
UV-sensing protein in brain of marine annelid zooplankton
SCIENCE DAILY Larvae of a marine ragworm Platynereis dumerilii have been studied as a zooplankton model, and possess photoreceptor cells in the brain to regulate circadian swimming behavior. This study revealed that a photoreceptive... 3 days
Cells in fish's spinal discs repair themselves
SCIENCE DAILY A unique repair mechanism has been discovered in the developing backbone of zebrafish that could give insight into why spinal discs of longer-lived organisms like humans degenerate with age. The repair mechanism protects fluid-filled... 3 days
Study shows how high fat diets can alter gut bacteria to combat harmful inflammation
NEWS MEDICAL Researchers at Case Western Reserve University School of Medicine have shown a high fat diet may lead to specific changes in gut bacteria that... 3 days
Researchers use supercomputers to study snake evolution, unique traits
PHYS.ORG Evolution takes eons, but it leaves marks on the genomes of organisms that can be detected with DNA sequencing and analysis. 3 days
Ecology insights improve plant biomass degradation by microorganisms
PHYS.ORG Microbes are widely used to break down plant biomass into sugars, which can be used as sustainable building blocks for novel biocompounds. Getting the right microbial community for this process is still... 3 days
How pythons regenerate their organs and other secrets of the snake genome
SCIENCE DAILY Snakes exhibit incredible evolutionary adaptations, including the ability to rapidly regenerate their organs and produce venom. Scientists studied these adaptations using genetic sequencing and... 3 days
HIV-positive women with cytomegalovirus likelier to pass virus that causes AIDS to infant
SCIENCE DAILY HIV-positive women with CMV in their urine at the time of labor and delivery are more than five times likelier than HIV-positive... 3 days
Holey pattern boosts coherence of nanomechanical membrane vibrations
SCIENCE DAILY Researchers have introduced a new type of nanomechanical resonator, in which a pattern of holes localizes vibrations to a small region in a 30 nm thick membrane. The pattern dramatically suppresses coupling... 3 days
Rare cells are 'window into the gut' for the nervous system
PHYS.ORG Specialized cells in the gut sense potentially noxious chemicals and trigger electrical impulses in nearby nerve fibers, according to a new study led by UC San... 3 days
Cells in fish's spinal discs repair themselves
PHYS.ORG Duke researchers have discovered a unique repair mechanism in the developing backbone of zebrafish that could give insight into why spinal discs of longer-lived organisms like humans degenerate with age. 3 days
Pathogen that causes sleeping sickness: Promising new target
SCIENCE DAILY The life-threatening African trypanosomiasis, also called sleeping sickness, is caused by protozoa of the species Trypanosoma brucei. A team of researchers has studied the pathogens and reported exciting news: The trypanosomes have... 3 days
Holey pattern boosts coherence of nanomechanical membrane vibrations
PHYS.ORG Researchers at the Niels Bohr Institute have introduced a new type of nanomechanical resonator, in which a pattern of holes localizes vibrations to a small region in a 30 nm thick membrane.... 3 days
Newly identified protection mechanism serves as first responder to cellular stress
SCIENCE DAILY A new type of rapid-response defense mechanism has been discovered that helps protect cells from environmental stress while giving slower, well-known protection systems time to act. 3 days
New insight into a central biological dogma on ion transport
PHYS.ORG New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a membrane protein complex that has roots in... 3 days
UV-sensing protein in the brain of a marine annelid zooplankton
PHYS.ORG Researchers at Institute for Molecular Sciences reported that a photoreceptive protein expressed in the brain a marine annelid zooplankton (Platynereis dumerilii) is UV-sensitive. This work was carried out... 3 days
Cheeeeese
From strands to droplets—new insights into DNA control
PHYS.ORG
Discovery of a new mechanism involved in the migration of cancer cells
PHYS.ORG
Ultra-thin camera creates images without lenses
PHYS.ORG
Wasp venom holds clues on how genes get new jobs
PHYS.ORG
Spectrin proteins spring into action to restore nucleus
PHYS.ORG
Unlock molecular secrets with mobile game BioBlox2-D
PHYS.ORG
Pre-clinical study suggests Parkinson's could start in gut endocrine cells
MNT
Ancient DNA reveals role of Near East and Egypt in cat domestication
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