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Research provides better understanding of how some cancer cells resist treatment
NEWS MEDICAL An international team of researchers led by Lucio Miele, MD, PhD, Professor and Chair of Genetics at LSU Health New Orleans School of Medicine, and Justin... 7 hours
New innovations in cell-free biotechnology
SCIENCE DAILY A new platform to conduct cell-free protein synthesis could lead to improved quality of manufactured protein therapeutics and biomaterials. 15 hours
Whale Murder Was Sexually Motivated, Whale Detectives Say
LIVE SCIENCE Biologists have accused a killer whale of murdering another whale's child. Here are the facts of the case. 15 hours
Bystander T cells can steal the show in resolving inflammation
SCIENCE DAILY New research reveals that bystander cell accumulation antagonizes rather than abets cell-killing by specific CTLs, curbing inflammation. The finding is noteworthy because that chief anti-inflammatory role has been... 15 hours
Gene boosts rice growth and yield in salty soil
PHYS.ORG Soil salinity poses a major threat to food security, greatly reducing the yield of agricultural crops. Rising global temperatures are expected to accelerate the buildup of salt in soil, placing... 16 hours
Team discovers a significant role for nitrate in the Arctic landscape
PHYS.ORG Nitrogen, an essential plant nutrient, is most readily absorbed by plants in its ammonium and nitrate forms. Because of the very low nitrate levels found in... 16 hours
Oriented chiral water wires in artificial transmembrane channels
Science Magazine Aquaporins (AQPs) feature highly selective water transport through cell membranes, where the dipolar orientation of structured water wires spanning the AQP pore is of considerable importance for the selective translocation of water... 16 hours
Critical advancements in achieving high power and stable nonprecious metal catalyst-based MEAs for real-world proton exchange membrane fuel cell applications
Science Magazine Despite great progress in the development of nonprecious... 16 hours
Stabilizing electrochemical interfaces in viscoelastic liquid electrolytes
Science Magazine Electrodeposition is a widely practiced method for creating metal, colloidal, and polymer coatings on conductive substrates. In the Newtonian liquid electrolytes typically used, the process is fundamentally unstable. The underlying instabilities have been linked... 16 hours
Unique genetic cassettes in a Thermoanaerobacterium contribute to simultaneous conversion of cellulose and monosugars into butanol
Science Magazine The demand for cellulosic biofuels is on the rise because of the anticipation for sustainable energy... 16 hours
Stretchable ultrasonic transducer arrays for three-dimensional imaging on complex surfaces
Science Magazine Ultrasonic imaging has been implemented as a powerful tool for noninvasive subsurface inspections of both structural and biological media. Current ultrasound probes are rigid and bulky and cannot... 16 hours
New innovations in cell-free biotechnology
PHYS.ORG A Northwestern University-led team has developed a new way to manufacture proteins outside of a cell that could have important implications in therapeutics and biomaterials. 16 hours
Mutations found in bassoon gene may help explain cause of rare brain disorder
NEWS MEDICAL Newly discovered gene mutations may help explain the cause of a disease that drastically impairs walking and thinking. 16 hours
Suppression of diabetes by accumulation of non-islet-specific CD8+ effector T cells in pancreatic islets
Science Magazine The inflammatory lesion at the pancreatic islet in type 1 diabetes (T1D) contains a heterogeneous infiltrate of T cells. In... 17 hours
Medical News Today: What to know about adenomyosis
MNT Adenomyosis is a condition where cells from the uterus lining grow into the uterus muscle. It is related to endometriosis and has similar symptoms, such as heavy, painful periods. Diagnosis involves ultrasound,... 17 hours
20-year-old assumptions in solar cell production refuted
SCIENCE DAILY Researchers have investigated the manufacturing process of solar cells. The researchers proved that assumptions on chemical processes that were commonplace among researchers and producers for the past 20 years are, in fact, inaccurate. 17 hours
Mutations of the bassoon gene causing new brain disorder
SCIENCE DAILY Newly discovered gene mutations may help explain the cause of a disease that drastically impairs walking and thinking. 18 hours
Staphylococcus aureus: A new mechanism involved in virulence and antibiotic resistance
SCIENCE DAILY A research team has characterized a Staphylococcus aureus gene involved in virulence, biofilm formation and resistance to certain antibiotics. These results open up new avenues for... 18 hours
How a genetic mutation can interfere with the powerhouses of cells
SCIENCE DAILY Scientists have identified the molecular consequences of a previously undefined genetic mutation. This mutation interferes with the functioning of the mitochondria, known as the powerhouses of... 18 hours
New Genetic Cause of Posterior Polymorphous Corneal Dystrophy Discovered
SCI-NEWS.COM A new genetic cause of an autosomal-dominant corneal endothelial dystrophy has been discovered in a study led by... 19 hours
Metastatic cancer cells modify bone remodeling with small RNA secretion in bone metastasis
SCIENCE DAILY Prostate cancer frequently metastasizes and spreads to bone, causing severe pain, fractures, and other complications. The mechanisms that allow cancer cells to... 19 hours
Growing and surviving: How proteins regulate the cell cycle
SCIENCE DAILY Cell division is the basis of all life. Even the smallest errors in this complex process can lead to grave diseases like cancer. Certain proteins have to be switched on... 19 hours
Breast cancer: New mechanism discovered for dissemination of metastatic tumor cells
SCIENCE DAILY Malignant tumor cells from a primary tumor have to pass into the bloodstream in order to form metastases in other organs. It is accepted in medical... 19 hours
Molecule discovered in dirt could help against multi-resistant bacteria
PHYS.ORG Mom always said you could get germs from playing in the dirt. Now, scientists have taken that advice a step further: a Rockefeller University team collected more than 2,000 soil... 20 hours
Researchers make breakthrough in light trapping technology for industrial multicrystalline silicon solar cells
PHYS.ORG Scientists from the Solar Energy Research Institute of Singapore (SERIS) at the National University of Singapore (NUS) have developed a low-cost and... 20 hours
Consuming a large meal temporarily costs dominant animals their leadership position
PHYS.ORG New research, led by the University of Glasgow and published today in Current Biology, found that fish who consumed a large meal had to move to... 20 hours
Researchers refute 20-year-old assumptions in solar cell production
PHYS.ORG Research led by the University of Luxembourg investigated the manufacturing process of solar cells. The researchers proved that assumptions on chemical processes that were commonplace among researchers and producers for the past... 20 hours
In a severe childhood neurodegeneration, novel mechanism found
SCIENCE DAILY Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells. The specific disease... 20 hours
Freezing frog cells for conservation
PHYS.ORG For the first time, Australian frog cells have been successfully frozen and re-grown in culture, offering hope of a new technique to safeguard endangered amphibians. 20 hours
Genetic switch activates transformation of stem cells into heart muscle cells
PHYS.ORG The discovery of a genetic switch that triggers stem cells to turn into heart cells is a major step in finding treatment for damaged hearts. 20 hours
Chemists develop new method to identify proteins
PHYS.ORG roteins are the worker bees of the cell, mainly ganging up to form macromolecular, multicomponent complexes to perform intricate cellular tasks. 21 hours
Microscopy trifecta examines how cells engulf nutrients, viruses
PHYS.ORG Scientists have a better understanding of a mechanism that allows cells to internalize beneficial nutrients and not-so-beneficial viruses, thanks to collaboration among researchers from two South Dakota universities and the National Institutes... 21 hours
Study tracks protein's role in stem cell function
PHYS.ORG MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body's effort to kill them by overexpressing... 21 hours
Want to discover truly alien life? Pack a genome sequencer
Science Magazine Scientists propose techniques to fingerprint nonterran biology 21 hours
NASA ‘clean’ room is contaminated with fungus
Science Magazine Microbes could spoil samples from Mars—and be mistaken for extraterrestrial life 22 hours
Medical News Today: Epithelial cells in urine: What does it mean?
MNT This article explains how and why urine tested for epithelial cells, what the results mean, and which conditions cause an increase in epithelial cells. 23 hours
Antimicrobial used in toiletries could become option against malaria
PHYS.ORG A study conducted at the University of Campinas (UNICAMP) in Brazil shows that triclosan, an antimicrobial compound used in soap, toothpaste, deodorant and many other products, can inhibit target genes... 23 hours
Researchers uncover cause of rare childhood neurodegenerative disease
NEWS MEDICAL Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells. 1 day
New test for urothelial cancers offers less invasive, more accurate detection
NEWS MEDICAL A new test for urothelial cancers could detect mutations in DNA that have been identified for those cancers earlier than traditional tests. The earlier detection of... 1 day
Restoring enzyme may help reverse effects of vascular aging, study shows
NEWS MEDICAL As people age, their blood-vessel density and blood flow decrease, which is why it's harder to maintain muscle mass after 40 and endurance in the later... 1 day
What gives the curl to curly hair? Sheep wool provides clues
NEWS MEDICAL There has been no research that explains what gives the curl to curly hair. To understand this, the researchers looked at the microscopic structure of the... 1 day
New computational method helps to identify tumor cell mutations with greater accuracy
NEWS MEDICAL A new computational method developed by researchers at the New York Genome Center allows scientists to identify rare gene mutations in cancer cells with... 1 day
Specific immune cells may help slow progression of ALS, research shows
NEWS MEDICAL New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the... 1 day
Secrets to curly hair found in New Zealand sheep
Science Magazine The key lies at the microscopic level—in the length of individual hair cells 1 day
Using light to turn yeast into biochemical factories
SCIENCE DAILY Researchers have used a combination of light and genetic engineering to controlling the metabolism, or basic chemical process, of a living cell. Building on techniques that already have transformed the field of... 1 day
New ALS gene points to common role of cytoskeleton in disease
SCIENCE DAILY Researchers have identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis (ALS). The discovery further implicates the role of cytoskeletal defects... 1 day
Gene-based test for urine detects, monitors bladder cancer
SCIENCE DAILY Researchers have developed a test for urine, gathered during a routine procedure, to detect DNA mutations identified with urothelial cancers. 1 day
Pap test fluids used in gene-based screening test for two gyn cancers
SCIENCE DAILY Cervical fluid samples gathered during routine Papanicolaou (Pap) tests are the basis of a new screening test for endometrial and ovarian cancers. 1 day
Early life experiences influence DNA in the adult brain
SCIENCE DAILY In the perennial question of nature versus nurture, a new study suggests an intriguing connection between the two. Scientists report that the type of mothering a female mouse provides her... 2 days
Antimicrobial used in toiletries could become option against malaria
SCIENCE DAILY Not only it inhibits enzymes essential to Plasmodium's survival in two key stages of its lifecycle in humans, but triclosan also performed well in tests against resistant parasites, an international... 2 days
Bacteria eat greenhouse gas with a side of protein
SCIENCE DAILY With the ability to leech heavy metals from the environment and digest a potent greenhouse gas, methanotrophic bacteria pull double duty when it comes to cleaning up the environment. But... 2 days
A possible cause for severe morning sickness, and linking mouse moms’ caretaking to brain changes in baby mice
Science Magazine Researchers are converging on which genes are linked to morning sickness—the nausea... 2 days
Bacteria eats greenhouse gas with a side of protein
PHYS.ORG With the ability to leech heavy metals from the environment and digest a potent greenhouse gas, methanotrophic bacteria pull double duty when it comes to cleaning up the environment. 2 days
Atacama mummy’s deformities were unduly sensationalized
SCIENCE-NEWS A malformed human mummy known as Ata has been sensationalized as alien. A DNA analysis helps overturn that misconception. 2 days
How bees defend against some controversial insecticides
SCIENCE-NEWS Some bees have enzymes that allow them to resist toxic compounds in some neonicotinoid pesticides. 2 days
Locally translated mTOR controls axonal local translation in nerve injury
Science Magazine How is protein synthesis initiated locally in neurons? We found that mTOR (mechanistic target of rapamycin) was activated and then up-regulated in injured axons, owing to local translation... 2 days
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
Science Magazine During metastasis, malignant cells escape the primary tumor, intravasate lymphatic vessels, and reach draining sentinel lymph nodes before they colonize... 2 days
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice
Science Magazine Lymph node metastases in cancer patients are associated with tumor aggressiveness, poorer prognoses, and... 2 days
The biosynthesis of methanobactin
Science Magazine Metal homeostasis poses a major challenge to microbes, which must acquire scarce elements for core metabolic processes. Methanobactin, an extensively modified copper-chelating peptide, was one of the earliest natural products shown to enable microbial acquisition of a metal other than... 2 days
Early life experience drives structural variation of neural genomes in mice
Science Magazine The brain is a genomic mosaic owing to somatic mutations that arise throughout development. Mobile genetic elements, including retrotransposons, are one source of somatic mosaicism in... 2 days
A single fungal MAP kinase controls plant cell-to-cell invasion by the rice blast fungus
Science Magazine Blast disease destroys up to 30% of the rice crop annually and threatens global food security. The blast fungus Magnaporthe... 2 days
Bioinspired spring origami
Science Magazine Origami enables folding of objects into a variety of shapes in arts, engineering, and biological systems. In contrast to well-known paper-folded objects, the wing of the earwig has an exquisite natural folding system that cannot be sufficiently described by current... 2 days
Cell geometry regulates differentiation
Science Magazine 2 days
The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies
Science Magazine The fine line between human health and disease can be driven by the interplay between host and microbial factors. This "metagenome" regulates cancer initiation, progression, and response to... 2 days
An alternate route for metastatic cells
Science Magazine 2 days
CAR T cell immunotherapy for human cancer
Science Magazine Adoptive T cell transfer (ACT) is a new area of transfusion medicine involving the infusion of lymphocytes to mediate antitumor, antiviral, or anti-inflammatory effects. The field has rapidly advanced from a promising form of... 2 days
Personalized vaccines for cancer immunotherapy
Science Magazine Cancer is characterized by an accumulation of genetic alterations. Somatic mutations can generate cancer-specific neoepitopes that are recognized by autologous T cells as foreign and constitute ideal cancer vaccine targets. Every tumor has its own unique composition of... 2 days
Cancer immunotherapy using checkpoint blockade
Science Magazine The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses in patients with a variety of cancers. This can be achieved by antibodies blocking the... 2 days
RNA targeting and translation in axons
Science Magazine 2 days
Researchers propose alternative treatment to target lymphoma signaling at its root
NEWS MEDICAL Non-Hodgkin lymphomas are cancers that affect white blood cells of the immune system called B-lymphocytes or B cells. Like cells in all cancers, the B cells... 2 days
Structure of a prehandover mammalian ribosomal SRPbulletSRP receptor targeting complex
Science Magazine Signal recognition particle (SRP) targets proteins to the endoplasmic reticulum (ER). SRP recognizes the ribosome synthesizing a signal sequence and delivers it to the SRP receptor (SR) on... 2 days
Genetic cause of deadly skin condition afflicting bull terriers discovered
PHYS.ORG In a new study published March 22nd, 2018 in PLOS Genetics, Anina Bauer of the University of Bern and a large international research team, report the discovery of... 2 days
Compound to prevent breast cancer cells from activating in brain
SCIENCE DAILY Researchers have used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain. 2 days
Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia
SCIENCE DAILY A research team has begun to unravel the role of RNA epigenetics and chromatin structure in the regulation of 5-azacytidine, a DNA hypomethylating agent... 2 days
Novel genomics tool enables more accurate identification of rare mutations in cancer cells
SCIENCE DAILY A new computational method allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity than currently available... 2 days
Gut bacteria determine speed of tumor growth in pancreatic cancer
SCIENCE DAILY The population of bacteria in the pancreas increases more than a thousand fold in patients with pancreatic cancer, and becomes dominated by species that prevent the immune system... 2 days
Gut microbiome may promote pancreatic cancer by inducing immune suppression
NEWS MEDICAL Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating... 2 days
This strange ‘alien’ skeleton is actually a human fetus with genetic bone defects
Science Magazine Extensive DNA sequencing reveals mutations which may explain skeleton’s odd appearance 2 days
Plants really do feed their friends
SCIENCE DAILY Researchers have discovered that as plants develop they craft their root microbiome, favoring microbes that consume very specific metabolites. Their study could help scientists identify ways to enhance the soil microbiome for improved carbon storage and... 2 days
Soybean genomes unmasked
PHYS.ORG Approximately 340 million metric tons of soybeans are produced globally each year, with the market for soybeans worth $40 billion in the U.S. alone. Having a map of soybean genes is key for breeders, who work to develop varieties that... 2 days
The universal language of hormones
SCIENCE DAILY Bioinformatics specialists have studied a specific class of hormones which is relevant for plants, bacteria and indirectly for humans, too. Their results challenge previous scientific assumptions. 2 days
Unique communication strategy discovered in stem cell pathway controlling plant growth
PHYS.ORG A team of plant geneticists at Cold Spring Harbor Laboratory (CSHL) has identified a protein receptor on stem cells involved in plant development that can issue... 2 days
Long thought to only cause a rare disease, this mutation may ward off malaria
PHYS.ORG A genetic mutation that may protect people from malaria, but was thought to be rare, is surprisingly common, suggest the... 2 days
The circadian clock controls the cell cycle and tumor growth in plants
PHYS.ORG Biological rhythms are ubiquitous in nature, from the beating of the heart to the rhythms of flowering plants. This rhythmicity is in some instances... 2 days
Toward precision medicine: First comprehensive look at human retinal cell diversity
PHYS.ORG In work that brings researchers closer to the goal of precision medicine approaches to treating glaucoma and other neurodegenerative vision diseases, a new IUPUI study has,... 2 days
Breakthrough in photonic biosensors could lead to super-accurate diagnostic and detectors
PHYS.ORG University Professor of Applied Physics Stephen Arnold and his team at the New York University Tandon School of Engineering have made a discovery that could lead... 2 days
Two genes likely play key role in extreme nausea and vomiting during pregnancy
SCIENCE DAILY A new study has identified two genes associated with hyperemesis gravidarum, whose cause has not been determined in previous studies. The genes,... 2 days
Brewing hoppy beer without the hops
SCIENCE DAILY Synthetic biology has created microbes that produce drugs, flavors, aromas and fuels. Now scientists have used the same tricks, with the help of CRISPR-Cas9, to get yeast to produce the flavor of hops. They added genes... 2 days
Targeting immune cells to slow progression of ALS
SCIENCE DAILY New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the disease, an important step towards developing... 2 days
Blackbirds in the city: Bad health, longer life
SCIENCE DAILY Blackbirds live longer in cities than in forests. But their telomeres, the repetitive stretches of DNA at the ends of the chromosomes, show that these city birds have a much poorer health... 2 days
Mitochondria mutation mystery solved: Random sorting helps get rid of duds
PHYS.ORG You probably know about the 23 pairs of chromosomes safely stowed in your cells' nuclei. That's where the vast majority of your genes can be found.... 2 days
Researchers prove complex connection between plants and what soil microbes eat
PHYS.ORG Researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and UC Berkeley have discovered that as plants develop they craft their root microbiome,... 2 days
Researchers Uncover Genetic History of Late Neanderthals
SCI-NEWS.COM An international team of scientists has sequenced the genomes of five Neanderthals who lived around 47,000 to 39,000 years ago (that is,... 2 days
Exclusive: ‘I’ve never seen anything like it’. Video of mating deep-sea anglerfish stuns biologists
Science Magazine VIDEO The rare observation was captured at a depth of 800 meters around Portugal’s Azores islands 2 days
Gut bacteria can mean life or death for birds
PHYS.ORG In her upcoming thesis at Lund University in Sweden, biologist Elin Videvall shows that the composition of gut bacteria in birds has a major impact on whether their offspring will... 2 days
The universal language of hormones
PHYS.ORG Bioinformatics specialists from the University of Würzburg have studied a specific class of hormones which is relevant for plants, bacteria and indirectly for humans, too. Their results challenge previous scientific assumptions. 2 days
Study reveals genes that cause extreme nausea and vomiting in pregnancy
NEWS MEDICAL Researchers have identified two genes that are associated with severe nausea and vomiting during pregnancy, a condition known of as hyperemesis gravidarum. 2 days
Medical News Today: How cats could help to treat HIV
MNT A study has unraveled the structure of a protein that fuels drug resistance in feline immunodeficiency virus. The finding may lead to new HIV treatments. 2 days
Researchers discover new accuracies in cancer-fighting, nano drug delivery
PHYS.ORG A promising discovery for advanced cancer therapy reveals that the efficiency of drug delivery in DNA nanostructures depends on their shapes, say researchers at Missouri University of Science and Technology... 2 days
Here's Why Cockroaches Can Survive Just About Anything
LIVE SCIENCE Their genes let them essentially eat insecticides for breakfast. 2 days
Exclusive: ‘I’ve never seen anything like it’. Video of mating deep-sea anglerfish stuns biologists
Science Magazine
Synthetic carbohydrate wards off pneumococcal infections
Researchers measure gene activity in single cells
Mutating DNA caught on film
Science Magazine
Brain genes related to innovation revealed in birds
You are not just you—you are a chimera
Will Smith hosts National Geographic's "One Strange Rock"
Parallel State