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A biomarker in the brain's circulation system may be Alzheimer's earliest warning
SCIENCE DAILY Leaks in the blood-brain barrier can provide early detection for Alzheimer's and diseases. 1 hour
Organs are not just bystanders, may be active participants in fighting autoimmune disease
SCIENCE DAILY Findings from mouse study suggest organs affected by autoimmune disease suppress immune cells using methods similar to those used by cancer cells... 1 hour
Cryo-EM reveals structure of protein responsible for regulating body temperature
PHYS.ORG A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising... 2 hours
Cryo-EM reveals structure of protein responsible for regulating body temperature
SCIENCE DAILY Scientists have revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and... 5 hours
Challenge continues in developing effective drug treatment for Alzheimer's disease
SCIENCE DAILY Nilvadipine shows no benefit for the treatment of Alzheimer's disease in mild and moderate stages of the disease, but further studies targeting the early phase of the disease... 5 hours
How nature, nurture shape the sleeping brain
SCIENCE DAILY Some patterns of electrical activity generated by the brain during sleep are inherited, according to a study of teenage twins. Pinpointing the relative contributions of biology and experience to sleep neurophysiology could inform therapies... 5 hours
Physical activity necessary to maintain heart-healthy lifestyle
SCIENCE DAILY Exercise and physical activity are of vast global importance to prevent and control the increasing problem of heart disease and stroke, according to a review article. 5 hours
Your Vision Matters: How to Protect Your Eyesight
NEWS MEDICAL VIDEO Dr. Neil Ebenezer from the charity Fight for Sight discusses the steps you can take to protect your eyesight into old age, and why research into ophthalmic diseases is desperately needed. 8 hours
Medical News Today: How the smell of disease can affect healthy people
MNT Disease can affect an individual's bodily odor. New research investigates to what extent this change in smell may impact groups that share a living... 8 hours
Study sheds light on how brain protein may be involved neurodevelopmental disorders
NEWS MEDICAL A study by researchers at Rockefeller University has shown that defects in a brain protein may underlie a number of neurodevelopmental disorders. 9 hours
TU Wien develops new remedy for celiac disease
NEWS MEDICAL Celiac disease is a fairly common disease, affecting one to two percent of the European population. It is expressed as a hypersensitivity to gluten, a protein found in cereals such as wheat,... 9 hours
Gene therapy approach could help treat mitochondrial diseases
NEWS MEDICAL Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people. 9 hours
Zapping mutant DNA in mitochondria could treat major class of genetic disease
Science Magazine Mouse studies show gene editing can reduce abundance of mutated mitochondrial DNA 9 hours
Eradicating Helicobacter pylori infections may be a key treatment for Parkinson's disease
SCIENCE DAILY While human genetic mutations are involved in a small number of Parkinson's disease (PD) cases, the vast majority of cases are of unknown environmental... 10 hours
Lumos acquires license for LUM-201 drug that promotes secretion of growth hormone
NEWS MEDICAL Lumos Pharma, Inc., a clinical stage biopharmaceutical company focused on development and commercialization of therapeutics for rare and neglected diseases, today announced that it... 11 hours
Quicker and simpler test to detect infectious disease in dogs
PHYS.ORG A team of researchers have proposed a new test that rapidly examines dogs for exposure to a parasite transmitted by sand flies. The test could be used in... 11 hours
Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD
NEWS MEDICAL Alexion Pharmaceuticals, Inc. today announced positive topline results from the Phase 3 PREVENT study of Soliris in patients... 12 hours
Number of people with respiratory diseases likely to increase if UK air pollution remains unchecked
NEWS MEDICAL The number of people suffering from respiratory indications and the severity of those already suffering from the various... 14 hours
Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI
NEWS MEDICAL Biogen and Eisai Co., Ltd. announced results from a recent analysis of the ongoing long-term extension Phase 1b... 16 hours
Cytox, AIBL announce expanded agreement to assess genetic risk for Alzheimer’s
NEWS MEDICAL Cytox, a precision medicine company which today is commercializing polygenic risk scoring approaches for assessing genetic risk for developing Alzheimer's disease and other neurological diseases, has... 17 hours
Researchers propose mechanism by which ASTN2 protein defects lead to brain disorders
NEWS MEDICAL In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular... 17 hours
Researchers highlight potential therapy for treating rare, deadly blood-clotting disorder
NEWS MEDICAL In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. 18 hours
Recent study helps predict probability of pregnant mothers to have child with autism
NEWS MEDICAL Researchers at Rensselaer Polytechnic Institute--led by Juergen Hahn, professor and head of biomedical engineering--are continuing to make remarkable progress with their research... 18 hours
Study of protein 'trafficker' provides insight into autism and other brain disorders
SCIENCE DAILY Researchers have discovered that the protein ASTN2 shuttles receptors away from the surface of neurons, a process that facilitates efficient brain activity. 22 hours
Stress-regulating brain area larger in depression, bipolar
MNT New research finds that the hypothalamus, the brain area that controls the stress response, is larger in people with affective disorders. 2 days
Medical News Today: Stress-regulating brain area larger in depression, bipolar
MNT New research finds that the hypothalamus, the brain area that controls the stress response, is larger in people with affective disorders. 2 days
A Trojan Horse delivery for treating a rare, potentially deadly, blood-clotting disorder
SCIENCE DAILY In proof-of-concept experiments, researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. The researchers deliver this therapeutic enzyme... 2 days
Latest research hints at predicting autism risk for pregnant mothers
SCIENCE DAILY Researchers are continuing to make remarkable progress with research focused on autism spectrum disorder (ASD). 2 days
Study sheds light on molecular mechanisms underlying progression of prion diseases
NEWS MEDICAL A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment. 3 days
Family history in blacks, Latinos associated with higher risk of AFib
NEWS MEDICAL Despite being the most common heart arrhythmia disorder in the U.S., there is not much research on the causes of atrial fibrillation in minority populations. 3 days
Researchers identify new genetic disorder in a human patient
NEWS MEDICAL Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described... 3 days
USC research uncovers previously unknown genetic risk factor for Alzheimer's disease
NEWS MEDICAL New research from USC has uncovered a previously unknown genetic risk factor for Alzheimer's disease and related dementias. The study provides insights on how these conditions,... 3 days
Insulin treatment shows great potential against chronic bowel inflammation
NEWS MEDICAL Millions of people take insulin every day to treat their diabetes. But diabetes is not the only disease on which insulin has an effect, it appears. 3 days
Study opens new avenues for treatment of Laing distal myopathy
NEWS MEDICAL New avenues are now being opened for future treatment of Laing distal myopathy, a rare disorder that causes muscles in the feet, hands and elsewhere to atrophy. In... 3 days
Scientists use mice to study transmission of Lyme disease bacteria by infected ticks
NEWS MEDICAL Lyme borreliosis is a disease caused by bacteria of the genus Borrelia that are transmitted by a bite from a tick of... 3 days
Cooking with wood or coal is linked to increased risk of respiratory illness and death
SCIENCE DAILY Burning wood or coal to cook food is associated with increased risk of hospitalization or dying from respiratory... 3 days
Gut fungus exacerbates asthma in antibiotic-treated mice
SCIENCE DAILY A non-pathogenic fungus can expand in the intestines of antibiotic-treated mice and enhance the severity of allergic airways disease, according to a new study. The findings suggest that alterations in gut microbiota induced by... 3 days
Study explores connection between sexuality and cognitive status in older adults
NEWS MEDICAL The number of people who live at home with Alzheimer's Disease (AD), a brain disease that causes abnormal changes that kill brain cells, is expected to... 3 days
Detecting epigenetic signature may help people stay ahead of IBD
SCIENCE DAILY Researchers have found an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of inflammatory bowel disease (IBD) called Crohn's disease. 3 days
Genomic dark matter activity connects Parkinson's and psychiatric diseases
SCIENCE DAILY Using a new technique known as laser-capture RNA seq, that involves cutting out dopamine neurons from a human brain section with a laser, investigators have cataloged more than 70,000 novel... 3 days
CHMP issues positive opinion supporting use of Trelegy Ellipta in broader group of COPD patients
NEWS MEDICAL GlaxoSmithKline plc and Innoviva, Inc. announced that the European Medicines Agency's Committee for Medicinal Products for Human Use... 3 days
EMA and CHMP issues positive opinion supporting use of Trelegy Ellipta in COPD patients
NEWS MEDICAL GlaxoSmithKline plc and Innoviva, Inc. announced that the European Medicines Agency's Committee for Medicinal Products for Human Use has issued... 3 days
Mediterranean-style diet may lower women's stroke risk
SCIENCE DAILY Following a Mediterranean-style diet (high in fish, fruits and nuts, vegetables and beans and lower in meat and dairy) reduced stroke risk in women over 40, but not in men. The Mediterranean-style diet reduced... 3 days
Mediterranean Diet Reduces Risk of Incident Stroke: Study
SCI-NEWS.COM A new study reveals that a traditional Mediterranean-style diet reduces stroke risk among white adults who are at high risk... 4 days
New outbreak of rare eye disease identified in contact lens wearers
NEWS MEDICAL A new outbreak of a rare but preventable eye infection that can cause blindness, has been identified in contact lens wearers in a new study led... 4 days
Neutrons produce first direct 3-D maps of water during cell membrane fusion
PHYS.ORG New 3-D maps of water distribution during cellular membrane fusion are accelerating scientific understanding of cell development, which could lead to new treatments for... 4 days
Researchers use neutrons to make first direct observations of water in lipid bilayers
NEWS MEDICAL New 3D maps of water distribution during cellular membrane fusion are accelerating scientific understanding of cell development, which could lead to new... 4 days
Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia
NEWS MEDICAL Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and... 4 days
Novel biomarker found in ovarian cancer patients can predict response to therapy
SCIENCE DAILY Researchers have identified an independent prognostic factor, cancer/testis antigen 45, that is associated with extended disease-free survival for women with advanced ovarian cancer. Patients... 4 days
Preventing a dengue outbreak at the 2020 Summer Olympics
SCIENCE DAILY New controls and frameworks are recommended to detect dengue and other infectious diseases and help prevent their spread during the 2020 summer Olympics and Paralympics being held in Tokyo, researchers... 4 days
Neutrons produce first direct 3-D maps of water during cell membrane fusion
SCIENCE DAILY New 3-D maps of water distribution during cellular membrane fusion are accelerating scientific understanding of cell development, which could lead to new treatments for... 4 days
Discovery could explain failed clinical trials for Alzheimer's, and provide a solution
SCIENCE DAILY A vicious feedback loop underlying brain degeneration in Alzheimer's disease may explain why so many drug trials have failed, according to researchers. Their study... 4 days
WATCH: Puppies to blame for sickening hundreds of people: CDC
ABC NEWS The Center for Disease Control says puppies from six different pet stores spread infectious bacteria in several states from 2016 to 2018. 4 days
First evaluation of benefits, harms of Alzheimer's screening for family members of older adults
NEWS MEDICAL With the support of a new $3 million, five-year National Institute on Aging grant, researchers from the Regenstrief Institute and... 4 days
Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes
NEWS MEDICAL Researchers at Case Western Reserve University have discovered how to quickly and accurately predict which lung cancer patients... 4 days
CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer
NEWS MEDICAL Certain genes that code for proteins have long been known to contribute to cancer progression. But in a... 4 days
Medical News Today: What are the early signs of COPD?
MNT Chronic obstructive pulmonary disease (COPD) refers to a group of lung diseases that cause breathing difficulties. COPD tends to get worse over time, so early detection and treatment... 4 days
Finding epigenetic signature appears to predict inflammation risk in serious type of IBD
NEWS MEDICAL With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling... 4 days
Progenitor cells for human bone and cartilage have been identified
NEWS MEDICAL Research published today describes for the first time the identification of human skeletal stem cells. The discovery may enable the development of novel therapeutic strategies for diseases that... 4 days
In depression the brain region for stress control is larger
SCIENCE DAILY Although depression is one of the leading psychiatric disorders, its cause remains unclear. A recent study found that those affected by depressive disorder have a larger hypothalamus compared... 4 days
Medical News Today: Signs and symptoms of STDs in men
MNT Sexually transmitted diseases (STDs), or sexually transmitted infections (STIs), can affect anyone, but some symptoms are different for men and women. In this article, we look at the... 4 days
New method enables accurate diagnosis of Alzheimer's disease
SCIENCE DAILY A new brain imaging method can show the spread of specific tau protein depositions, which are unique to cases with Alzheimer's. 4 days
Analysis of sea squirt embryo reveals key molecules in dopaminergic neuron differentiation
SCIENCE DAILY Researchers have used a novel approach for analyzing the central nervous system of a proto-vertebrate to identify a regulatory cocktail that induces the creation... 4 days
Fatty acids can slow down an overheated immune system
SCIENCE DAILY The STING protein is normally an important part of our immune system, but in some autoimmune diseases it is itself the source of the disease. The pharmaceutical industry is therefore... 4 days
Solving real-world problems
PHYS.ORG Tools developed by Håvard Rue have transformed data analysis, interpretation and communication, and are applied broadly: from modeling the spread of infectious diseases to mapping fish stocks. 4 days
Pfizer’s 20vPnC vaccine receives Breakthrough Therapy designation from FDA
NEWS MEDICAL Pfizer Inc. announced today that its 20-Valent Pneumococcal Conjugate Vaccine candidate, PF-06482077, received Breakthrough Therapy designation from the US Food and Drug Administration for the prevention of invasive disease and... 4 days
Survey: 91% of people around the world believe medical research will result in dementia cure
NEWS MEDICAL A new survey from Novartis, Amgen and Banner Alzheimer’s Institute, along with Alzheimer’s Disease International, shows that 91%... 4 days
AMSBIO launches circulating tumor DNA Reference Standards
NEWS MEDICAL AMSBIO announce the launch of a new range of circulating tumor DNA Reference Standards for cancer disease management research. 5 days
Restoring cells to an uninfected state once a virus is destroyed
PHYS.ORG New research, pioneered by a first year Ph.D. student and researchers at the University of St Andrews' School of Biology, has identified an important new component... 5 days
Emergex signs MoU with Brazil’s Fiocruz for development of viral vaccines
NEWS MEDICAL Emergex Vaccines Holding Limited, a biotechnology company pioneering a new approach to synthetic vaccine development in the field of infectious diseases, today announces that it has... 5 days
New guidance for treatment of bone loss in hematologic stem cell transplant Recipients
NEWS MEDICAL Hematopoietic stem cell transplantation is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and... 5 days
Geroscience takes center stage in Journal of the American Medical Association
NEWS MEDICAL Geroscience--the burgeoning research field that focuses on the genetic, molecular, and cellular mechanisms that make aging a major risk factor for most chronic diseases as we... 5 days
Detection of BFD virus in parrots in 8 new countries raises concerns for threatened species
NEWS MEDICAL Beak and feather disease virus in wild parrot populations has been detected in eight new countries, raising concerns... 5 days
Alzheimer’s diagnosis might become simpler with new brain imaging method
NEWS MEDICAL Accurate diagnosis of Alzheimer’s disease may be difficult in most patients as similar symptoms can be seen in several other disease conditions as well. 5 days
Medical News Today: Is carrageenan safe to eat?
MNT Carrageenan is a controversial food additive. It is FDA-approved, but some scientists believe that it can cause inflammation, bowel disorders, and even certain cancers. In this article, we look at the research... 5 days
Twitter Chat » NIMH Twitter Chat: Depression
NIMH In recognition of National Depression Screening Day, NIMH is hosting a Twitter chat on depression, a common but serious mood disorder. The event will be held on Thursday, October 11, 2018, 11:00AM―12:00 PM ET.... 5 days
Medical News Today: What are the stages of Crohn's disease?
MNT Crohn's disease causes chronic inflammation in the digestive tract. Although Crohn's disease tends to get worse over time, symptoms can vary considerably and may sometimes disappear for weeks... 5 days
What are the stages of Crohn's disease?
MNT Crohn's disease causes chronic inflammation in the digestive tract. Although Crohn's disease tends to get worse over time, symptoms can vary considerably and may sometimes disappear for weeks or even years. For this reason,... 5 days
Anti-inflammatory protein promotes healthy gut bacteria to curb obesity
SCIENCE DAILY Scientists have discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the... 5 days
Multi-directional activity control of cellular processes as a new tool
SCIENCE DAILY The spatial and temporal dynamics of proteins or organelles plays a crucial role in controlling various cellular processes and in development of diseases. Yet, acute control of activity... 5 days
Zombie cells found in brains of mice prior to cognitive loss
SCIENCE DAILY Zombie cells are the ones that can't die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are... 5 days
Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10
Science Magazine Coxsackievirus A10 (CVA10) recently emerged as a major pathogen of hand, foot, and mouth disease and herpangina in children worldwide, and lack of a vaccine or... 5 days
[Editors' Choice] Identifying and targeting residual leukemic cells
Science Magazine Targeting leukemia regenerating cells following chemotherapy can prevent relapse of the disease. 5 days
[Research Articles] Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice
Science Magazine β-Site APP (amyloid precursor protein) cleaving enzyme 1 (BACE1) is the β-secretase enzyme that initiates production of the toxic amyloid-β... 5 days
[Research Articles] Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria
Science Magazine Congenital erythropoietic porphyria is a rare autosomal recessive disease produced by deficient activity of uroporphyrinogen III synthase, the... 5 days
[Research Articles] Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome
Science Magazine Severe fever with thrombocytopenia syndrome (SFTS) caused by a recently identified bunyavirus, SFTSV, is an emerging... 5 days
Deadly plant disease threatens $250M rose business
PHYS.ORG The outlook for American-grown roses is becoming a bit less rosy, with the spread of an incurable virus that's causing major damage to the nation's $250-million-a-year rose business. 5 days
Green tea compound helps siRNA slip inside cells
PHYS.ORG Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. Although many of these claims still need to be verified in the clinic, an antioxidant... 5 days
Seeing pesticides spread through insect bodies
PHYS.ORG Pesticides have been linked with declining honey bee numbers, raising questions about how we might replace the many essential uses of these chemicals in agriculture and for control of insect-borne diseases. As many governments seek to... 5 days
Antioxidant in green tea helps sneak therapeutic RNAs into cells
NEWS MEDICAL Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. 5 days
Body support device helps people learn to walk again after a stroke, trauma
PHYS.ORG A Purdue University researcher with a passion to use engineering technology to improve health care has created a weight support system to... 5 days
Green tea compound helps siRNA slip inside cells
SCIENCE DAILY Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. Although many of these claims still need to be verified in the clinic, an antioxidant... 5 days
Chemicals linked to endocrine disorder in older pet cats
SCIENCE DAILY New research suggests that there may be a link between higher levels of per- and polyfluoroalkyl substances (PFAS) in the environment and higher levels of hyperthyroidism in pet cats as... 6 days
Despite studies, health effects of coal-burning power plants remain unknown
PHYS.ORG A review of studies over the past 30 years provides a body of evidence that people living near coal-fired power plants have higher death rates and at earlier... 6 days
Study finds why some human genes are more popular with biomedical researchers
NEWS MEDICAL Historical bias is a key reason why biomedical researchers continue to study the same 10 percent of all human genes while ignoring many genes... 6 days
New tau-PET method shows superior accuracy in diagnosing Alzheimer's disease
NEWS MEDICAL Diagnosing Alzheimer's disease can be difficult, as several other conditions can cause similar symptoms. Now a new brain imaging method can show the spread of specific tau protein... 6 days
From Syria to Southern California: Refugees seek care for wounds of war
NEWS MEDICAL In his native Syria, Mahmoud spent months in captivity in a crowded room three floors underground, never seeing the sun. Disease spread quickly among... 6 days
TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal
NEWS MEDICAL As part of a national initiative to solve children's diseases, the Translational Genomics Research Institute and the Pacific Pediatric Neuro-Oncology... 6 days
Experts to present research on prevention, management of dysphagia at international conference
NEWS MEDICAL Over 800 delegates from 46 countries will attend the 8th annual European Society for Swallowing Disorders Congress taking place in Dublin next week to... 6 days
New fungus found to cause cankers and declines in pistachio trees in Sicily, Italy
PHYS.ORG Starting in the spring of 2010, farmers from Sicily—the major pistachio production area of Italy—have been reporting a previously unknown... 6 days
Your Vision Matters: How to Protect Your Eyesight
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Escape from the heat island
PHYS.ORG
The Digital Health Platform That’s Tackling Chronic Health Conditions
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Zimbabwe declares cholera emergency
NEWS MEDICAL